{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T01:50:37Z","timestamp":1791597037702,"version":"4.3.4"},"reference-count":57,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82302592"],"award-info":[{"award-number":["82302592"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["iScience"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.isci.2026.117291","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T15:54:54Z","timestamp":1787932494000},"page":"117291","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pan-Ras-In-1 triggers cell wall lysis to eradicate Staphylococcus aureus"],"prefix":"10.1016","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3285-3905","authenticated-orcid":false,"given":"Weihua","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinjuan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinru","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingjie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Can","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongrong","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongpeng","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangyou","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.isci.2026.117291_bib1","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1007\/s00277-024-06154-4","article-title":"Trends in the epidemiology of intravascular device-associated bacteremia among French hematology patients: insights from the SPIADI prospective multicenter study, 2020-2024","volume":"104","author":"van der Mee-Marquet","year":"2025","journal-title":"Ann. Hematol."},{"key":"10.1016\/j.isci.2026.117291_bib2","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1093\/annonc\/mds468","article-title":"Predictors of bloodstream infection associated with permanently implantable venous port in solid cancer patients","volume":"24","author":"Chen","year":"2013","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.isci.2026.117291_bib3","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1007\/s00134-005-2621-5","article-title":"Indwelling time and risk of infection of dialysis catheters in critically ill cancer patients","volume":"31","author":"Harb","year":"2005","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.isci.2026.117291_bib4","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0140-6736(21)02724-0","article-title":"Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis","volume":"399","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.isci.2026.117291_bib5","doi-asserted-by":"crossref","first-page":"325","DOI":"10.7326\/0003-4819-97-3-325","article-title":"Community-acquired methicillin-resistant Staphylococcus aureus infections: a new source for nosocomial outbreaks","volume":"97","author":"Saravolatz","year":"1982","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.isci.2026.117291_bib6","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1097\/MD.0b013e318030d344","article-title":"Catheter-related Staphylococcus aureus bacteremia in cancer patients: high rate of complications with therapeutic implications","volume":"86","author":"Ghanem","year":"2007","journal-title":"Medicine (Baltim.)"},{"key":"10.1016\/j.isci.2026.117291_bib7","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1634\/theoncologist.2012-0029","article-title":"Characteristics and outcomes of methicillin-resistant staphylococcus aureus bloodstream infections in patients with cancer treated with vancomycin: 9-year experience at a comprehensive cancer center","volume":"17","author":"Mahajan","year":"2012","journal-title":"Oncologist"},{"key":"10.1016\/j.isci.2026.117291_bib8","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1080\/14787210.2020.1752665","article-title":"Repurposed anti-cancer drugs: the future for anti-infective therapy?","volume":"18","author":"Quezada","year":"2020","journal-title":"Expert Rev. Anti Infect. Ther."},{"key":"10.1016\/j.isci.2026.117291_bib9","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.cell.2017.02.006","article-title":"Multivalent Small-Molecule Pan-RAS Inhibitors","volume":"168","author":"Welsch","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.isci.2026.117291_bib10","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.049093","article-title":"Ras signaling and RREB1 are required for the dissociation of medial edge epithelial cells in murine palatogenesis","volume":"15","author":"Inubushi","year":"2022","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.isci.2026.117291_bib11","first-page":"1","article-title":"Envelope Structures of Gram-Positive Bacteria","volume":"404","author":"Rajagopal","year":"2017","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.isci.2026.117291_bib12","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1039\/D2NP00084A","article-title":"Natural products acting against S. aureus through membrane and cell wall disruption","volume":"40","author":"Kumar","year":"2023","journal-title":"Nat. Prod. Rep."},{"key":"10.1016\/j.isci.2026.117291_bib13","doi-asserted-by":"crossref","first-page":"5010","DOI":"10.1038\/s41598-019-41461-1","article-title":"The pentaglycine bridges of Staphylococcus aureus peptidoglycan are essential for cell integrity","volume":"9","author":"Monteiro","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2026.117291_bib14","doi-asserted-by":"crossref","DOI":"10.1093\/femsre\/fuac025","article-title":"Staphylococcus aureus cell wall maintenance - the multifaceted roles of peptidoglycan hydrolases in bacterial growth, fitness, and virulence","volume":"46","author":"Wang","year":"2022","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.isci.2026.117291_bib15","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1128\/JB.185.8.2635-2643.2003","article-title":"The Staphylococcus aureus cidAB operon: evaluation of its role in regulation of murein hydrolase activity and penicillin tolerance","volume":"185","author":"Rice","year":"2003","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.isci.2026.117291_bib16","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/nrmicro3136","article-title":"Bacterial programmed cell death: making sense of a paradox","volume":"12","author":"Bayles","year":"2014","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.isci.2026.117291_bib17","doi-asserted-by":"crossref","first-page":"2468","DOI":"10.1128\/JB.01545-10","article-title":"Staphylococcus aureus CidA and LrgA proteins exhibit holin-like properties","volume":"193","author":"Ranjit","year":"2011","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.isci.2026.117291_bib18","doi-asserted-by":"crossref","first-page":"4030","DOI":"10.1128\/JB.00611-08","article-title":"The N-acetylmannosamine transferase catalyzes the first committed step of teichoic acid assembly in Bacillus subtilis and Staphylococcus aureus","volume":"191","author":"D'Elia","year":"2009","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.isci.2026.117291_bib19","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s44259-025-00098-z","article-title":"Design, synthesis and optimization of TarO inhibitors as multifunctional antibiotics against Methicillin-resistant Staphylococcus aureus","volume":"3","author":"Zhong","year":"2025","journal-title":"npj Antimicrob. Resist."},{"key":"10.1016\/j.isci.2026.117291_bib20","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s40121-017-0146-1","article-title":"Infections in Cancer Patients with Solid Tumors: A Review","volume":"6","author":"Rolston","year":"2017","journal-title":"Infect. Dis. Ther."},{"key":"10.1016\/j.isci.2026.117291_bib21","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1086\/381972","article-title":"Clinical relevance of bacteriostatic versus bactericidal mechanisms of action in the treatment of Gram-positive bacterial infections","volume":"38","author":"Pankey","year":"2004","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.isci.2026.117291_bib22","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/jac\/dkh076","article-title":"Antibiotic-induced persistence of cytotoxic Staphylococcus aureus in non-phagocytic cells","volume":"53","author":"Krut","year":"2004","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.isci.2026.117291_bib23","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1126\/science.284.5418.1318","article-title":"Bacterial biofilms: a common cause of persistent infections","volume":"284","author":"Costerton","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.isci.2026.117291_bib24","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01912-19","article-title":"Subinhibitory Concentrations of Mupirocin Stimulate Staphylococcus aureus Biofilm Formation by Upregulating cidA","volume":"64","author":"Jin","year":"2020","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.isci.2026.117291_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2022.105734","article-title":"The role of bacterial ATP-binding cassette (ABC) transporters in pathogenesis and virulence: Therapeutic and vaccine potential","volume":"171","author":"Akhtar","year":"2022","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.isci.2026.117291_bib26","doi-asserted-by":"crossref","first-page":"4767","DOI":"10.1128\/JB.00348-09","article-title":"The Staphylococcus aureus LytSR two-component regulatory system affects biofilm formation","volume":"191","author":"Sharma-Kuinkel","year":"2009","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.isci.2026.117291_bib27","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1146\/annurev-micro-041222-125931","article-title":"Cell Growth and Division of Staphylococcus aureus","volume":"78","author":"Pinho","year":"2024","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.isci.2026.117291_bib28","doi-asserted-by":"crossref","first-page":"8113","DOI":"10.1073\/pnas.0610226104","article-title":"The cidA murein hydrolase regulator contributes to DNA release and biofilm development in Staphylococcus aureus","volume":"104","author":"Rice","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.isci.2026.117291_bib29","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/s41592-024-02553-7","article-title":"A peptide-centric local stability assay enables proteome-scale identification of the protein targets and binding regions of diverse ligands","volume":"22","author":"Li","year":"2025","journal-title":"Nat. Methods"},{"key":"10.1016\/j.isci.2026.117291_bib30","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1093\/infdis\/156.5.741","article-title":"Virulence studies, in mice, of transposon-induced mutants of Staphylococcus aureus differing in capsule size","volume":"156","author":"Lee","year":"1987","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.isci.2026.117291_bib31","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.00761-22","article-title":"CidA and LrgA: a \u201cHole\u201d Lot More than Programmed Cell Death","volume":"13","author":"Laabei","year":"2022","journal-title":"mBio"},{"key":"10.1016\/j.isci.2026.117291_bib32","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s12275-014-4087-z","article-title":"Phage lysis: three steps, three choices, one outcome","volume":"52","author":"Young","year":"2014","journal-title":"J. Microbiol."},{"key":"10.1016\/j.isci.2026.117291_bib33","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1111\/mmi.13433","article-title":"The LysR-type transcriptional regulator, CidR, regulates stationary phase cell death in Staphylococcus aureus","volume":"101","author":"Chaudhari","year":"2016","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.isci.2026.117291_bib34","article-title":"The Staphylococcus aureus CidA and LrgA Proteins Are Functional Holins Involved in the Transport of By-Products of Carbohydrate Metabolism","volume":"13","author":"Endres","year":"2021","journal-title":"mBio"},{"key":"10.1016\/j.isci.2026.117291_bib35","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1038\/s41589-021-00803-9","article-title":"Modification of cell wall polysaccharide guides cell division in Streptococcus mutans","volume":"17","author":"Zamakhaeva","year":"2021","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.isci.2026.117291_bib36","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.tcsw.2018.05.001","article-title":"Nascent teichoic acids insertion into the cell wall directs the localization and activity of the major pneumococcal autolysin LytA","volume":"2","author":"Bonnet","year":"2018","journal-title":"Cell Surf."},{"key":"10.1016\/j.isci.2026.117291_bib37","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1111\/j.1365-2958.2009.07007.x","article-title":"Role of staphylococcal wall teichoic acid in targeting the major autolysin Atl","volume":"75","author":"Schlag","year":"2010","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.isci.2026.117291_bib38","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00541-21","article-title":"Clemastine Inhibits the Biofilm and Hemolytic of Staphylococcus aureus through the GdpP Protein","volume":"10","author":"Shang","year":"2022","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.isci.2026.117291_bib39","doi-asserted-by":"crossref","DOI":"10.1128\/msphere.00564-23","article-title":"Novel small-molecule compound YH7 inhibits the biofilm formation of Staphylococcus aureus in a sarX-dependent manner","volume":"9","author":"Xiao","year":"2024","journal-title":"mSphere"},{"key":"10.1016\/j.isci.2026.117291_bib40","doi-asserted-by":"crossref","DOI":"10.1002\/ardp.202300656","article-title":"Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents","volume":"357","author":"Khalifa","year":"2024","journal-title":"Arch. Pharm."},{"key":"10.1016\/j.isci.2026.117291_bib41","doi-asserted-by":"crossref","DOI":"10.1128\/genomeA.00855-14","article-title":"Draft Genome Sequence of Staphylococcus aureus subsp. aureus Strain HG003, an NCTC8325 Derivative","volume":"2","author":"Sassi","year":"2014","journal-title":"Genome Announc."},{"key":"10.1016\/j.isci.2026.117291_bib42","doi-asserted-by":"crossref","first-page":"10429","DOI":"10.1021\/acs.jmedchem.1c00858","article-title":"Rational Design of Dipicolylamine-Containing Carbazole Amphiphiles Combined with Zn(2+) as Potent Broad-Spectrum Antibacterial Agents with a Membrane-Disruptive Mechanism","volume":"64","author":"Liu","year":"2021","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.isci.2026.117291_bib43","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1016\/S0140-6736(00)04403-2","article-title":"Whole genome sequencing of meticillin-resistant Staphylococcus aureus","volume":"357","author":"Kuroda","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.isci.2026.117291_bib44","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1056\/NEJMoa055356","article-title":"Methicillin-resistant S. aureus infections among patients in the emergency department","volume":"355","author":"Moran","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.isci.2026.117291_bib45","doi-asserted-by":"crossref","first-page":"4539","DOI":"10.2147\/IDR.S332777","article-title":"Functional Insights of MraZ on the Pathogenicity of Staphylococcus aureus","volume":"14","author":"Wang","year":"2021","journal-title":"Infect. Drug Resist."},{"key":"10.1016\/j.isci.2026.117291_bib46","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00045-23","article-title":"Small-Molecule Compound CY-158-11 Inhibits Staphylococcus aureus Biofilm Formation","volume":"11","author":"Shen","year":"2023","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.isci.2026.117291_bib47","doi-asserted-by":"crossref","first-page":"4492","DOI":"10.1128\/JB.00315-09","article-title":"Genome sequencing and comparative analysis of Klebsiella pneumoniae NTUH-K2044, a strain causing liver abscess and meningitis","volume":"191","author":"Wu","year":"2009","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.isci.2026.117291_bib48","doi-asserted-by":"crossref","first-page":"2770","DOI":"10.1093\/jac\/dkv204","article-title":"Mapping the resistance-associated mobilome of a carbapenem-resistant Klebsiella pneumoniae strain reveals insights into factors shaping these regions and facilitates generation of a 'resistance-disarmed' model organism","volume":"70","author":"Bi","year":"2015","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.isci.2026.117291_bib49","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.2147\/IDR.S465699","article-title":"Characteristic of KPC-12, a KPC Variant Conferring Resistance to Ceftazidime-Avibactam in the Carbapenem-Resistant Klebsiella pneumoniae ST11-KL47 Clone Background","volume":"17","author":"Han","year":"2024","journal-title":"Infect. Drug Resist."},{"key":"10.1016\/j.isci.2026.117291_bib50","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1038\/35023079","article-title":"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen","volume":"406","author":"Stover","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.isci.2026.117291_bib51","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.plasmid.2005.05.005","article-title":"Allelic replacement in Staphylococcus aureus with inducible counter-selection","volume":"55","author":"Bae","year":"2006","journal-title":"Plasmid"},{"key":"10.1016\/j.isci.2026.117291_bib52","doi-asserted-by":"crossref","DOI":"10.1080\/21505594.2024.2411540","article-title":"The roles of cell wall inhibition responsive protein CwrA in the pathogenicity of Staphylococcus aureus","volume":"15","author":"Han","year":"2024","journal-title":"Virulence"},{"key":"10.1016\/j.isci.2026.117291_bib53","article-title":"Naturally Derived Malabaricone B as a Promising Bactericidal Candidate Targeting Multidrug-Resistant Staphylococcus aureus also Possess Synergistic Interactions with Clinical","volume":"12","author":"Sivadas","year":"2023","journal-title":"Antibiotics (Basel)."},{"key":"10.1016\/j.isci.2026.117291_bib54","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.1923","article-title":"Fast gapped-read alignment with Bowtie 2","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.isci.2026.117291_bib55","doi-asserted-by":"crossref","first-page":"16858","DOI":"10.1021\/acs.jmedchem.4c01860","article-title":"Membrane-Targeting Amphiphilic Honokiol Derivatives Containing an Oxazole Moiety as Potential Antibacterials against Methicillin-Resistant Staphylococcus aureus","volume":"67","author":"Yang","year":"2024","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.isci.2026.117291_bib56","doi-asserted-by":"crossref","first-page":"4623","DOI":"10.1021\/acs.jproteome.5c00365","article-title":"PELSA-Decipher: A Software Tool for the Processing and Interpretation of Ligand-Protein Interaction Data Sets Acquired by PELSA","volume":"24","author":"Zhu","year":"2025","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.isci.2026.117291_bib57","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/978-1-4939-3676-2_15","article-title":"Analysis of Cell Wall Teichoic Acids in Staphylococcus aureus","volume":"1440","author":"Covas","year":"2016","journal-title":"Methods Mol. Biol."}],"container-title":["iScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004226026696?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004226026696?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T01:16:35Z","timestamp":1791594995000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589004226026696"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":57,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S2589004226026696"],"URL":"https:\/\/doi.org\/10.1016\/j.isci.2026.117291","relation":{},"ISSN":["2589-0042"],"issn-type":[{"value":"2589-0042","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pan-Ras-In-1 triggers cell wall lysis to eradicate Staphylococcus aureus","name":"articletitle","label":"Article Title"},{"value":"iScience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.isci.2026.117291","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117291"}}