{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T22:23:40Z","timestamp":1794349420110,"version":"4.9.0"},"reference-count":70,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002241","name":"CREST","doi-asserted-by":"publisher","award":["JPMJCR21P1"],"award-info":[{"award-number":["JPMJCR21P1"]}],"id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["25zf0127010"],"award-info":[{"award-number":["25zf0127010"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["25wm0625324"],"award-info":[{"award-number":["25wm0625324"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["25zf0127012"],"award-info":[{"award-number":["25zf0127012"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP24ym0126815"],"award-info":[{"award-number":["JP24ym0126815"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["25KJ2028"],"award-info":[{"award-number":["25KJ2028"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24K22086"],"award-info":[{"award-number":["24K22086"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009029","name":"JST Adaptable and Seamless Technology Transfer Program Through Target-driven R and D","doi-asserted-by":"publisher","award":["JPMJTR20UT"],"award-info":[{"award-number":["JPMJTR20UT"]}],"id":[{"id":"10.13039\/501100009029","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005927","name":"Daiichi Sankyo Foundation of Life Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005927","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020963","name":"Japan Science and Technology Agency Moonshot Research and Development Program","doi-asserted-by":"publisher","award":["JPMJMS239F"],"award-info":[{"award-number":["JPMJMS239F"]}],"id":[{"id":"10.13039\/501100020963","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["iScience"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.isci.2026.117713","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T21:00:36Z","timestamp":1790110836000},"page":"117713","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lateralized vagal oxytocin receptor signaling separately controls feeding and socioemotional functions via hypothalamic oxytocin neurons"],"prefix":"10.1016","volume":"29","author":[{"given":"Kengo","family":"Iba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Masuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rika","family":"Kitano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kento","family":"Ohbayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukio","family":"Ago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Nagai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Furuyashiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chikara","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0655-4384","authenticated-orcid":false,"given":"Yusaku","family":"Iwasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.isci.2026.117713_bib1","first-page":"97","article-title":"Oxytocin--anatomy and functional assignments: a minireview","volume":"39","author":"Kiss","year":"2005","journal-title":"Endocr. Regul."},{"key":"10.1016\/j.isci.2026.117713_bib2","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.neuron.2023.12.022","article-title":"Single-neuron projectomes of mouse paraventricular hypothalamic nucleus oxytocin neurons reveal mutually exclusive projection patterns","volume":"112","author":"Li","year":"2024","journal-title":"Neuron"},{"key":"10.1016\/j.isci.2026.117713_bib3","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/nrendo.2017.115","article-title":"The effects of oxytocin on eating behaviour and metabolism in humans","volume":"13","author":"Lawson","year":"2017","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.isci.2026.117713_bib4","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12700","article-title":"Role of oxytocin in the control of stress and food intake","volume":"31","author":"Onaka","year":"2019","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.isci.2026.117713_bib5","doi-asserted-by":"crossref","DOI":"10.1002\/cph4.70010","article-title":"Vagal Sensory Gut-Brain Pathways That Control Eating-Satiety and Beyond","volume":"15","author":"Mendez-Hernandez","year":"2025","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.isci.2026.117713_bib6","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/j.cell.2019.10.031","article-title":"Genetic Identification of Vagal Sensory Neurons That Control Feeding","volume":"179","author":"Bai","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.isci.2026.117713_bib7","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1016\/j.celrep.2019.04.096","article-title":"An Atlas of Vagal Sensory Neurons and Their Molecular Specialization","volume":"27","author":"Kupari","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.isci.2026.117713_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.conb.2025.103058","article-title":"Gut-brain communication: Functional anatomy of vagal afferents","volume":"93","author":"Berthoud","year":"2025","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.isci.2026.117713_bib9","doi-asserted-by":"crossref","DOI":"10.14814\/phy2.70636","article-title":"Gut sensing of food ingredients and interoception-mediated regulation of feeding and glucose metabolism","volume":"13","author":"Iba","year":"2025","journal-title":"Physiol. Rep."},{"key":"10.1016\/j.isci.2026.117713_bib10","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.18632\/aging.100408","article-title":"Peripheral oxytocin treatment ameliorates obesity by reducing food intake and visceral fat mass","volume":"3","author":"Maejima","year":"2011","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.isci.2026.117713_bib11","doi-asserted-by":"crossref","first-page":"R360","DOI":"10.1152\/ajpregu.00344.2014","article-title":"Peripheral oxytocin activates vagal afferent neurons to suppress feeding in normal and leptin-resistant mice: a route for ameliorating hyperphagia and obesity","volume":"308","author":"Iwasaki","year":"2015","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.isci.2026.117713_bib12","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.bbrc.2019.09.039","article-title":"Relay of peripheral oxytocin to central oxytocin neurons via vagal afferents for regulating feeding","volume":"519","author":"Iwasaki","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.isci.2026.117713_bib13","doi-asserted-by":"crossref","first-page":"3493","DOI":"10.1111\/cns.14282","article-title":"Paraventricular nucleus-central amygdala oxytocinergic projection modulates pain-related anxiety-like behaviors in mice","volume":"29","author":"Li","year":"2023","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.isci.2026.117713_bib14","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1126\/science.aan4994","article-title":"Gating of social reward by oxytocin in the ventral tegmental area","volume":"357","author":"Hung","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.isci.2026.117713_bib15","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1016\/S0165-0327(12)70004-6","article-title":"Epidemiology of depression and diabetes: a systematic review","volume":"142","author":"Roy","year":"2012","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.isci.2026.117713_bib16","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jcjd.2014.11.006","article-title":"Depression and Risk for Diabetes: A Meta-Analysis","volume":"39","author":"Yu","year":"2015","journal-title":"Can. J. Diabetes"},{"key":"10.1016\/j.isci.2026.117713_bib17","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1001\/archgenpsychiatry.2010.2","article-title":"Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies","volume":"67","author":"Luppino","year":"2010","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.isci.2026.117713_bib18","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/s41467-017-02488-y","article-title":"GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose","volume":"9","author":"Iwasaki","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.isci.2026.117713_bib19","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1038\/s41586-020-2425-3","article-title":"The liver-brain-gut neural arc maintains the T(reg) cell niche in the gut","volume":"585","author":"Teratani","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.isci.2026.117713_bib20","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.cell.2018.08.049","article-title":"A Neural Circuit for Gut-Induced Reward","volume":"175","author":"Han","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.isci.2026.117713_bib21","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1007\/s00213-005-0293-z","article-title":"Anxiolytic-like activity of oxytocin in male mice: behavioral and autonomic evidence, therapeutic implications","volume":"185","author":"Ring","year":"2006","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.isci.2026.117713_bib22","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.2006421","article-title":"Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala","volume":"17","author":"Tunstall","year":"2019","journal-title":"PLoS Biol."},{"key":"10.1016\/j.isci.2026.117713_bib23","doi-asserted-by":"crossref","first-page":"3464","DOI":"10.1038\/s41596-020-0382-9","article-title":"A standardized social preference protocol for measuring social deficits in mouse models of autism","volume":"15","author":"Rein","year":"2020","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.isci.2026.117713_bib24","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.cell.2011.08.040","article-title":"Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits","volume":"147","author":"Pe\u00f1agarikano","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.isci.2026.117713_bib25","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0134572","article-title":"Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder","volume":"10","author":"Brunner","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.isci.2026.117713_bib26","doi-asserted-by":"crossref","first-page":"7582","DOI":"10.1038\/s41380-021-01227-6","article-title":"Oxytocin administration in neonates shapes hippocampal circuitry and restores social behavior in a mouse model of autism","volume":"26","author":"Bertoni","year":"2021","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.isci.2026.117713_bib27","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.jnutbio.2018.03.009","article-title":"Short-chain fatty acids suppress food intake by activating vagal afferent neurons","volume":"57","author":"Goswami","year":"2018","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.isci.2026.117713_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0285589","article-title":"Dynamic modulation of pulsatile activities of oxytocin neurons in lactating wild-type mice","volume":"18","author":"Yaguchi","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.isci.2026.117713_bib29","doi-asserted-by":"crossref","first-page":"4651","DOI":"10.1113\/JP290717","article-title":"Peripheral cholecystokinin promotes thermogenesis via vagal afferent signalling, hypothalamic oxytocin and sympathetic outflow to brown adipose tissue","volume":"604","author":"Masuda","year":"2026","journal-title":"J. Physiol."},{"key":"10.1016\/j.isci.2026.117713_bib30","doi-asserted-by":"crossref","first-page":"5021","DOI":"10.1523\/JNEUROSCI.0307-22.2022","article-title":"Whole-Brain Wiring Diagram of Oxytocin System in Adult Mice","volume":"42","author":"Son","year":"2022","journal-title":"J. Neurosci."},{"key":"10.1016\/j.isci.2026.117713_bib31","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.95215","article-title":"Single transcript level atlas of oxytocin and the oxytocin receptor in the mouse brain","volume":"15","author":"Ryu","year":"2026","journal-title":"eLife"},{"key":"10.1016\/j.isci.2026.117713_bib32","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12839","article-title":"Endogenous oxytocin inhibits hypothalamic corticotrophin-releasing hormone neurones following acute hypernatraemia","volume":"32","author":"Pati","year":"2020","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.isci.2026.117713_bib33","doi-asserted-by":"crossref","first-page":"3418","DOI":"10.2337\/db13-0663","article-title":"Oxytocin reduces reward-driven food intake in humans","volume":"62","author":"Ott","year":"2013","journal-title":"Diabetes"},{"key":"10.1016\/j.isci.2026.117713_bib34","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1002\/oby.21069","article-title":"Oxytocin reduces caloric intake in men","volume":"23","author":"Lawson","year":"2015","journal-title":"Obesity"},{"key":"10.1016\/j.isci.2026.117713_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.psyneuen.2024.107032","article-title":"A phase II randomised controlled trial of intranasal oxytocin in anorexia nervosa","volume":"164","author":"Maguire","year":"2024","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.isci.2026.117713_bib36","doi-asserted-by":"crossref","first-page":"4389","DOI":"10.1073\/pnas.0910249107","article-title":"Promoting social behavior with oxytocin in high-functioning autism spectrum disorders","volume":"107","author":"Andari","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.isci.2026.117713_bib37","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1038\/npp.2010.123","article-title":"Oxytocin attenuates amygdala reactivity to fear in generalized social anxiety disorder","volume":"35","author":"Labuschagne","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.isci.2026.117713_bib38","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1038\/s41467-020-14845-5","article-title":"Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans","volume":"11","author":"Martins","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.isci.2026.117713_bib39","doi-asserted-by":"crossref","first-page":"3083","DOI":"10.1038\/s41380-023-02075-2","article-title":"Sniffing oxytocin: Nose to brain or nose to blood?","volume":"28","author":"Yao","year":"2023","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.isci.2026.117713_bib40","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics14020323","article-title":"Effects of Intranasal Administration of Oxytocin and Vasopressin on Social Cognition and Potential Routes and Mechanisms of Action","volume":"14","author":"Yao","year":"2022","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.isci.2026.117713_bib41","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1177\/10738584241268754","article-title":"Navigating Central Oxytocin Transport: Known Realms and Uncharted Territories","volume":"31","author":"Parmaksiz","year":"2025","journal-title":"Neuroscientist"},{"key":"10.1016\/j.isci.2026.117713_bib42","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3389\/fnbeh.2015.00245","article-title":"Distinct BOLD Activation Profiles Following Central and Peripheral Oxytocin Administration in Awake Rats","volume":"9","author":"Ferris","year":"2015","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.isci.2026.117713_bib43","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1152\/physrev.2001.81.2.629","article-title":"The oxytocin receptor system: structure, function, and regulation","volume":"81","author":"Gimpl","year":"2001","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.isci.2026.117713_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2021.147625","article-title":"Dedicated C-fiber vagal sensory afferent pathways to the paraventricular nucleus of the hypothalamus","volume":"1769","author":"Fawley","year":"2021","journal-title":"Brain Res."},{"key":"10.1016\/j.isci.2026.117713_bib45","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/jne.12019","article-title":"Involvement of prolactin-releasing peptide in the activation of oxytocin neurones in response to food intake","volume":"25","author":"Yamashita","year":"2013","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.isci.2026.117713_bib46","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0304-3940(99)00831-9","article-title":"Central administration of prolactin-releasing peptide stimulates oxytocin release in rats","volume":"276","author":"Maruyama","year":"1999","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.isci.2026.117713_bib47","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/s42255-024-01205-6","article-title":"Mechanosensation of the heart and gut elicits hypometabolism and vigilance in mice","volume":"7","author":"Scott","year":"2025","journal-title":"Nat. Metab."},{"key":"10.1016\/j.isci.2026.117713_bib48","doi-asserted-by":"crossref","first-page":"4404","DOI":"10.1016\/j.febslet.2014.10.010","article-title":"Oxytocinergic circuit from paraventricular and supraoptic nuclei to arcuate POMC neurons in hypothalamus","volume":"588","author":"Maejima","year":"2014","journal-title":"FEBS Lett."},{"key":"10.1016\/j.isci.2026.117713_bib49","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1146\/annurev-neuro-102320-102847","article-title":"Oxytocin, Neural Plasticity, and Social Behavior","volume":"44","author":"Froemke","year":"2021","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.isci.2026.117713_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.autneu.2021.102887","article-title":"Functional anatomy of the vagus system - Emphasis on the somato-visceral interface","volume":"236","author":"Neuhuber","year":"2021","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.isci.2026.117713_bib51","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26052053","article-title":"Neurons Co-Expressing GLP-1, CCK, and PYY Receptors Particularly in Right Nodose Ganglion and Innervating Entire GI Tract in Mice","volume":"26","author":"Lansbury","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.isci.2026.117713_bib52","doi-asserted-by":"crossref","DOI":"10.3389\/fnana.2024.1422403","article-title":"The parasympathetic and sensory innervation of the proximal and distal colon in male mice","volume":"18","author":"Wang","year":"2024","journal-title":"Front. Neuroanat."},{"key":"10.1016\/j.isci.2026.117713_bib53","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/cne.21736","article-title":"Distribution and neurochemical identification of pancreatic afferents in the mouse","volume":"509","author":"Fasanella","year":"2008","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.isci.2026.117713_bib54","doi-asserted-by":"crossref","first-page":"C741","DOI":"10.1152\/ajpcell.00932.2025","article-title":"Comparison of receptor expression and cholecystokinin signaling between left and right nodose ganglia","volume":"330","author":"Ritchey","year":"2026","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.isci.2026.117713_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2025.116507","article-title":"Molecular and functional asymmetry in Cckar-expressing vagal sensory neurons","volume":"44","author":"Welch","year":"2025","journal-title":"Cell Rep."},{"key":"10.1016\/j.isci.2026.117713_bib56","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S1474-4422(02)00220-X","article-title":"Vagus-nerve stimulation for the treatment of epilepsy","volume":"1","author":"Ben-Menachem","year":"2002","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.isci.2026.117713_bib57","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.brs.2024.12.1191","article-title":"Vagus nerve stimulation in treatment-resistant depression: A one-year, randomized, sham-controlled trial","volume":"18","author":"Conway","year":"2025","journal-title":"Brain Stimul."},{"key":"10.1016\/j.isci.2026.117713_bib58","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.brs.2008.02.001","article-title":"A pilot study of vagus nerve stimulation (VNS) for treatment-resistant anxiety disorders","volume":"1","author":"George","year":"2008","journal-title":"Brain Stimul."},{"key":"10.1016\/j.isci.2026.117713_bib59","doi-asserted-by":"crossref","DOI":"10.1111\/obr.13309","article-title":"A systematic review on neuromodulation therapies for reducing body weight in patients with obesity","volume":"22","author":"Gouveia","year":"2021","journal-title":"Obes. Rev."},{"key":"10.1016\/j.isci.2026.117713_bib60","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/epi.13678","article-title":"Vagus nerve stimulation: Surgical technique of implantation and revision and related morbidity","volume":"58","author":"Giordano","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.isci.2026.117713_bib61","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.biopsych.2015.05.003","article-title":"Intranasal Oxytocin: Myths and Delusions","volume":"79","author":"Leng","year":"2016","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.isci.2026.117713_bib62","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1172\/JCI78361","article-title":"Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells","volume":"125","author":"Boh\u00f3rquez","year":"2015","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.isci.2026.117713_bib63","article-title":"Limited evidence for anatomical contacts between intestinal GLP-1 cells and vagal neurons in male mice","volume":"14","author":"Cao","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2026.117713_bib64","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-31361-1","article-title":"Vasopressin and oxytocin in sensory neurones: expression, exocytotic release and regulation by lactation","volume":"8","author":"Dayanithi","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.isci.2026.117713_bib65","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.regpep.2006.03.008","article-title":"Oxytocin is expressed throughout the human gastrointestinal tract","volume":"135","author":"Ohlsson","year":"2006","journal-title":"Regul. Pept."},{"key":"10.1016\/j.isci.2026.117713_bib66","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/s41586-023-06830-x","article-title":"Control of lipolysis by a population of oxytocinergic sympathetic neurons","volume":"625","author":"Li","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.isci.2026.117713_bib67","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1152\/physrev.00031.2017","article-title":"The Oxytocin Receptor: From Intracellular Signaling to Behavior","volume":"98","author":"Jurek","year":"2018","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.isci.2026.117713_bib68","article-title":"An obligate role of oxytocin neurons in diet induced energy expenditure","volume":"7","author":"Wu","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.isci.2026.117713_bib69","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0423-21.2022","article-title":"Targeting Neurons with Functional Oxytocin Receptors: A Novel Set of Simple Knock-In Mouse Lines for Oxytocin Receptor Visualization and Manipulation","volume":"9","author":"Inoue","year":"2022","journal-title":"eNeuro"},{"key":"10.1016\/j.isci.2026.117713_bib70","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.1016\/j.cell.2025.03.007","article-title":"Channel synapse mediates neurotransmission of airway protective chemoreflexes","volume":"188","author":"Soma","year":"2025","journal-title":"Cell"}],"container-title":["iScience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004226030944?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589004226030944?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T21:52:39Z","timestamp":1794347559000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589004226030944"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":70,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S2589004226030944"],"URL":"https:\/\/doi.org\/10.1016\/j.isci.2026.117713","relation":{},"ISSN":["2589-0042"],"issn-type":[{"value":"2589-0042","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lateralized vagal oxytocin receptor signaling separately controls feeding and socioemotional functions via hypothalamic oxytocin neurons","name":"articletitle","label":"Article Title"},{"value":"iScience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.isci.2026.117713","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117713"}}