{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:19:48Z","timestamp":1790698788795,"version":"4.1.0"},"reference-count":71,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T00:00:00Z","timestamp":1164931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trends in Immunology"],"published-print":{"date-parts":[[2006,12]]},"DOI":"10.1016\/j.it.2006.10.001","type":"journal-article","created":{"date-parts":[[2006,10,15]],"date-time":"2006-10-15T11:37:09Z","timestamp":1160912229000},"page":"545-551","source":"Crossref","is-referenced-by-count":36,"title":["Peptidoglycan: a major aetiological factor for psoriasis?"],"prefix":"10.1016","volume":"27","author":[{"given":"Barbara S.","family":"Baker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Powles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lionel","family":"Fry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.it.2006.10.001_bib1","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.0022-202X.2004.23611.x","article-title":"Psoriasis phenotype at disease outset: clinical characterization of 400 adult cases","volume":"124","author":"Mallbris","year":"2005","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib2","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1038\/nri1689","article-title":"Getting under the skin: the immunogenetics of psoriasis","volume":"5","author":"Bowcock","year":"2005","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.it.2006.10.001_bib3","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3109\/03009745509164855","article-title":"Significance of infections in origin of psoriasis","volume":"1","author":"Norrlind","year":"1955","journal-title":"Acta Rheumatol. Scand."},{"key":"10.1016\/j.it.2006.10.001_bib4","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1084\/jem.57.4.571","article-title":"A serological differentiation of human and other groups of haemolytic streptococci","volume":"57","author":"4 McCarty","year":"1933","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.it.2006.10.001_bib5","series-title":"Recent Advances in Streptococci and Streptococcal Diseases","first-page":"334","article-title":"Beta haemolytic streptococcal types associated with psoriasis","author":"Belew","year":"1985"},{"key":"10.1016\/j.it.2006.10.001_bib6","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1001\/archderm.128.1.39","article-title":"The role of streptococcal infection in the initiation of guttate psoriasis","volume":"128","author":"Telfer","year":"1992","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib7","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1159\/000252565","article-title":"A study of the incidence of haemolytic streptococci in the throat in patients with psoriasis vulgaris, with reference to their role in the pathogenesis of the disease","volume":"140","author":"Tervaert","year":"1970","journal-title":"Dermatologica"},{"key":"10.1016\/j.it.2006.10.001_bib8","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1046\/j.1365-2273.1998.00084.x","article-title":"Tonsillitis and chronic psoriasis","volume":"23","author":"Wardrop","year":"1998","journal-title":"Clin. Otolaryngol."},{"key":"10.1016\/j.it.2006.10.001_bib9","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1046\/j.1365-2133.2003.05552.x","article-title":"Streptococcal throat infections and exacerbation of chronic plaque psoriasis: a prospective study","volume":"149","author":"Gudjonsson","year":"2003","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib10","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1097\/00005537-199705000-00016","article-title":"Intracellular reservoir of Streptococcus pyogenes in vivo: a possible explanation for recurrent pharyngotonsillitis","volume":"107","author":"Osterlund","year":"1997","journal-title":"Laryngoscope"},{"key":"10.1016\/j.it.2006.10.001_bib11","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1016\/S0140-6736(97)12452-7","article-title":"Prevalence of internalisation-associated gene, prtF1, among persisting group A streptococcal strains isolated from asymptomatic carriers","volume":"352","author":"Neeman","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.it.2006.10.001_bib12","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/S1369-5274(99)80010-1","article-title":"Streptococcal invasion","volume":"2","author":"Molinari","year":"1999","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.it.2006.10.001_bib13","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1136\/ard.62.10.976","article-title":"Role of peptidoglycan subtypes in the pathogenesis of bacterial cell wall arthritis","volume":"62","author":"Simelyte","year":"2003","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.it.2006.10.001_bib14","first-page":"399","article-title":"Antibodies to streptococcal cell wall in psoriatic arthritis and cutaneous psoriasis","volume":"15","author":"Rantakokko","year":"1997","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.it.2006.10.001_bib15","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1017\/S0022215100082694","article-title":"Improvement of recalcitrant psoriasis vulgaris after tonsillectomy","volume":"90","author":"Nyfors","year":"1976","journal-title":"J. Laryngol. Otol."},{"key":"10.1016\/j.it.2006.10.001_bib16","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1365-2273.1996.tb01108.x","article-title":"Clearance of recalcitrant psoriasis after tonsillectomy","volume":"21","author":"Hone","year":"1996","journal-title":"Clin. Otolaryngol."},{"key":"10.1016\/j.it.2006.10.001_bib17","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s00403-005-0559-7","article-title":"Incidental detection of S. pyogenes-DNA in psoriatic skin by PCR","volume":"296","author":"Weisenseel","year":"2005","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.it.2006.10.001_bib18","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/S0022-3476(88)80577-8","article-title":"Guttate psoriasis associated with perianal streptococcal disease","volume":"113","author":"Honig","year":"1988","journal-title":"J. Pediatr."},{"key":"10.1016\/j.it.2006.10.001_bib19","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1056\/NEJMoa021481","article-title":"Endogenous antimicrobial peptides and skin infections in atopic dermatitis","volume":"347","author":"Ong","year":"2002","journal-title":"New Engl. J. Med."},{"key":"10.1016\/j.it.2006.10.001_bib20","doi-asserted-by":"crossref","first-page":"3262","DOI":"10.4049\/jimmunol.171.6.3262","article-title":"Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes","volume":"171","author":"Nomura","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.it.2006.10.001_bib21","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1046\/j.1523-1747.2000.00919.x","article-title":"Skin CD4+ T cells produce interferon-\u03b3 in vitro in response to streptococcal antigens in chronic plaque psoriasis","volume":"114","author":"Brown","year":"2000","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib22","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s004030100218","article-title":"Non-M protein on the cell wall and membrane of group A streptococci induces IFN-\u03b3 production by dermal CD4+ T cells in psoriasis","volume":"293","author":"Brown","year":"2001","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.it.2006.10.001_bib23","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1046\/j.1365-3083.2003.01309.x","article-title":"Selective response of dermal Th-1 cells to 20\u201350kDa streptococcal cell wall proteins in chronic plaque psoriasis","volume":"58","author":"Baker","year":"2003","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.it.2006.10.001_bib24","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1002\/path.1954","article-title":"Peptidoglycan and peptidoglycan-specific Th-1 cells in psoriasis lesions","volume":"209","author":"Baker","year":"2006","journal-title":"J. Pathol."},{"key":"10.1016\/j.it.2006.10.001_bib25","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1111\/j.1346-8138.2002.tb00179.x","article-title":"Increased microorganisms DNA levels in peripheral blood monocytes from psoriatic patients using PCR with universal ribosomal RNA primers","volume":"29","author":"Okubo","year":"2002","journal-title":"J. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib26","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1093\/brain\/124.8.1544","article-title":"Bacterial peptidoglycan and immune reactivity in the central nervous system in multiple sclerosis","volume":"124","author":"Schrijver","year":"2001","journal-title":"Brain"},{"key":"10.1016\/j.it.2006.10.001_bib27","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S1096-2190(00)00010-X","article-title":"Systemic aspects of psoriasis: an integrative model based on intestinal etiology","volume":"2","author":"McMillin","year":"1999","journal-title":"Integr. Med."},{"key":"10.1016\/j.it.2006.10.001_bib28","doi-asserted-by":"crossref","first-page":"808","DOI":"10.4049\/jimmunol.174.2.808","article-title":"Proinflammatory bacterial peptidoglycan as a cofactor for the development of central nervous system autoimmune disease","volume":"174","author":"Visser","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.it.2006.10.001_bib29","doi-asserted-by":"crossref","first-page":"20260","DOI":"10.1074\/jbc.M909168199","article-title":"Human monocytes activated by Staphylococcus aureus, peptidoglycan, and endotoxin","volume":"275","author":"Wang","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.it.2006.10.001_bib30","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1177\/42.11.7930525","article-title":"Detection of intestinal flora-derived bacterial antigen complexes in splenic macrophages of rats","volume":"42","author":"Kool","year":"1994","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.it.2006.10.001_bib31","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1002\/1529-0131(200010)43:10<2160::AID-ANR3>3.0.CO;2-T","article-title":"Antigen-presenting cells containing bacterial peptidoglycan in synovial tissues of rheumatoid arthritis patients coexpress costimulatory molecules and cytokines","volume":"43","author":"Schrijver","year":"2000","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.it.2006.10.001_bib32","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1006\/clin.1994.1090","article-title":"The presence of peptidoglycan\u2013polysaccharide complexes in the bowel wall and the cellular responses to these complexes in Crohn's disease","volume":"71","author":"Klasen","year":"1994","journal-title":"Clin. Immunol. Immunopathol."},{"key":"10.1016\/j.it.2006.10.001_bib33","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1046\/j.1365-2249.2001.01563.x","article-title":"Skin T cell proliferative response to M protein and other cell wall and membrane proteins of group A streptococci in chronic plaque psoriasis","volume":"124","author":"Baker","year":"2001","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.it.2006.10.001_bib34","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1023\/A:1025377702283","article-title":"Reduced IFN-\u03b3 responses associated with HLA-DR15 presentation of streptococcal cell wall proteins to dermal Th-1 cells in psoriasis","volume":"23","author":"Baker","year":"2003","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.it.2006.10.001_bib35","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.it.2003.10.007","article-title":"Lessons from Nod2 studies: towards a link between Crohn's disease and bacterial sensing","volume":"24","author":"Girardin","year":"2003","journal-title":"Trends Immunol."},{"key":"10.1016\/j.it.2006.10.001_bib36","first-page":"962","article-title":"Increased incidence of psoriasis in patients with Crohn's disease and their relatives","volume":"85","author":"Lee","year":"1990","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.it.2006.10.001_bib37","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1046\/j.1462-5822.2003.00304.x","article-title":"Nods, Nalps, and Naip: intracellular regulators of bacterial-induced inflammation","volume":"5","author":"Chamaillard","year":"2003","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.it.2006.10.001_bib38","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1086\/377159","article-title":"The International Psoriasis Genetics Study: assessing linkage to 14 candidate susceptibility loci in a cohort of 942 affected sib pairs","volume":"73","author":"International Psoriasis Genetics Consortium","year":"2003","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.it.2006.10.001_bib39","first-page":"540","article-title":"Exclusion of CARD15\/NOD2 as a candidate susceptibility gene to psoriasis in the Italian population","volume":"12","author":"Borgiani","year":"2002","journal-title":"Eur. J. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib40","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1136\/ard.2004.029157","article-title":"Lack of genetic association of the three more common polymorphisms of CARD15 with psoriatic arthritis and psoriasis in a German cohort","volume":"64","author":"Lascorz","year":"2005","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.it.2006.10.001_bib41","doi-asserted-by":"crossref","first-page":"3596","DOI":"10.1002\/art.21393","article-title":"Evidence for common genetic control in pathways of inflammation for Crohn's disease and psoriatic arthritis","volume":"52","author":"Ho","year":"2005","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.it.2006.10.001_bib42","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1086\/378076","article-title":"CARD15: a pleiotropic autoimmune gene that confers susceptibility to psoriatic arthritis","volume":"73","author":"Rahman","year":"2003","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.it.2006.10.001_bib43","doi-asserted-by":"crossref","first-page":"34686","DOI":"10.1074\/jbc.M105566200","article-title":"Peptidoglycan recognition proteins. A novel family of four human innate immunity pattern recognition molecules","volume":"276","author":"Liu","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.it.2006.10.001_bib44","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1182\/blood-2005-02-0530","article-title":"Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity","volume":"106","author":"Cho","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.it.2006.10.001_bib45","doi-asserted-by":"crossref","first-page":"49044","DOI":"10.1074\/jbc.M307758200","article-title":"Human peptidoglycan recognition protein-L is an N-acetylmuramoyl-L-alanine amidase","volume":"278","author":"Wang","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.it.2006.10.001_bib46","doi-asserted-by":"crossref","first-page":"5895","DOI":"10.1074\/jbc.M511631200","article-title":"Peptidoglycan recognition proteins are a new class of human bactericidal proteins","volume":"281","author":"Lu","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.it.2006.10.001_bib47","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1046\/j.1523-1747.2001.01311.x","article-title":"Fine mapping of the PSORS4 psoriasis susceptibility region on chromosome 1q21","volume":"116","author":"Capon","year":"2001","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib48","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s00439-005-0115-8","article-title":"Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the Epidermal Differentiation Complex and are candidate genes for the Psors4 locus on chromosome 1q21","volume":"119","author":"Sun","year":"2006","journal-title":"Hum. Genet."},{"key":"10.1016\/j.it.2006.10.001_bib49","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1086\/303075","article-title":"Genomewide scan in German families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13","volume":"67","author":"Lee","year":"2000","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.it.2006.10.001_bib50","first-page":"375","article-title":"Inflammatory properties of peptidoglycan are decreased after degradation with human N-acetylmuramoyl-L-alanine amidase","volume":"8","author":"Hoijer","year":"1997","journal-title":"Eur. Cytokine Netw."},{"key":"10.1016\/j.it.2006.10.001_bib51","doi-asserted-by":"crossref","first-page":"7949","DOI":"10.1128\/MCB.24.18.7949-7957.2004","article-title":"Innate immune responses in peptidoglycan recognition protein L-deficient mice","volume":"24","author":"Xu","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.it.2006.10.001_bib52","doi-asserted-by":"crossref","first-page":"7216","DOI":"10.1128\/IAI.73.11.7216-7225.2005","article-title":"Peptidoglycan recognition protein 2 (N-acetylmuramoyl-L-alanine amidase) is induced in keratinocytes by bacteria through p38 kinase pathway","volume":"73","author":"Wang","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.it.2006.10.001_bib53","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/ng1096-231","article-title":"Evidence that a locus for familial psoriasis maps to chromosome 4q","volume":"14","author":"Matthews","year":"1996","journal-title":"Nat. Genet."},{"key":"10.1016\/j.it.2006.10.001_bib54","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1111\/j.0022-202X.2004.22607.x","article-title":"Meta-analysis of genome-wide studies of psoriasis susceptibility reveals linkage to chromosomes 6p21 and 4q28-31 in Caucasian and Chinese Han population","volume":"122","author":"Sagoo","year":"2004","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib55","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.4049\/jimmunol.176.11.7104","article-title":"Identical T-cell receptor \u03b2-chain rearrangements in streptococcal angina and skin lesions of patients with psoriasis vulgaris","volume":"176","author":"Diluvio","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.it.2006.10.001_bib56","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1084\/jem.181.2.747","article-title":"Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin-12 production","volume":"181","author":"Leung","year":"1995","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.it.2006.10.001_bib57","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1111\/j.1365-3083.1988.tb01507.x","article-title":"An altered response by psoriatic keratinocytes to gamma-interferon","volume":"28","author":"Baker","year":"1988","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.it.2006.10.001_bib58","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1365-2133.1989.tb01795.x","article-title":"Decreased growth inhibition by recombinant gamma interferon is associated with increased transforming growth factor-alpha production in keratinocytes cultured from psoriatic lesions","volume":"121","author":"Nickoloff","year":"1989","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib59","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1128\/MMBR.36.4.407-477.1972","article-title":"Peptidoglycan types of bacterial cell walls and their taxonomic implications","volume":"36","author":"Schleifer","year":"1972","journal-title":"Bacteriol. Rev."},{"key":"10.1016\/j.it.2006.10.001_bib60","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1056\/NEJM194509062331003","article-title":"The possible inter-relation of psoriasis and Streptococcus faecalis","volume":"233","author":"Swartz","year":"1945","journal-title":"New Engl. J. Med."},{"key":"10.1016\/j.it.2006.10.001_bib61","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1038\/jid.1953.56","article-title":"The relationship of Streptococcus faecalis to psoriasis","volume":"20","author":"Robinson","year":"1953","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib62","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1172\/JCI118263","article-title":"Evidence for a streptococcal superantigen-driven process in acute guttate psoriasis","volume":"96","author":"Leung","year":"1995","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.it.2006.10.001_bib63","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1111\/j.1365-2133.1984.tb04678.x","article-title":"Epidermal T lymphocytes and HLA-DR expression in psoriasis","volume":"110","author":"Baker","year":"1984","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib64","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0002-9440(10)65109-7","article-title":"Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis","volume":"155","author":"Nickoloff","year":"1999","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.it.2006.10.001_bib65","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/nm0595-442","article-title":"Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis","volume":"1","author":"Gottlieb","year":"1995","journal-title":"Nat. Med."},{"key":"10.1016\/j.it.2006.10.001_bib66","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1365-2249.2004.00600.x","article-title":"Peripheral blood T cell responses to keratin peptides that share sequences with streptococcal M proteins are largely restricted to skin-homing CD8+ T cells","volume":"138","author":"Johnston","year":"2004","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.it.2006.10.001_bib67","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/j.0022-202X.2004.22709.x","article-title":"Identification of autoantigens in psoriatic plaques using expression cloning","volume":"123","author":"Jones","year":"2004","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib68","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jdermsci.2005.01.001","article-title":"HLA-DR B1*04, *07-restricted epitopes on keratin 17 for autoreactive T cells in psoriasis","volume":"38","author":"Shen","year":"2005","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.it.2006.10.001_bib69","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/j.1365-2133.1993.tb00477.x","article-title":"Restricted T-cell receptor V\u03b2 gene usage in the skin of patients with guttate and chronic plaque psoriasis","volume":"129","author":"Lewis","year":"1993","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.it.2006.10.001_bib70","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/S1473-3099(02)00222-0","article-title":"Superantigens: microbial agents that corrupt immunity","volume":"2","author":"Llewelyn","year":"2002","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.it.2006.10.001_bib71","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1046\/j.1365-2133.1998.1390s3017.x","article-title":"The role of superantigens in human diseases: therapeutic implications for the treatment of skin diseases","volume":"139","author":"Leung","year":"1998","journal-title":"Br. J. Dermatol."}],"container-title":["Trends in Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471490606002882?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471490606002882?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,18]],"date-time":"2020-04-18T16:51:09Z","timestamp":1587228669000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1471490606002882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":71,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["S1471490606002882"],"URL":"https:\/\/doi.org\/10.1016\/j.it.2006.10.001","relation":{},"ISSN":["1471-4906"],"issn-type":[{"value":"1471-4906","type":"print"}],"subject":[],"published":{"date-parts":[[2006,12]]}}}