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Rev."},{"key":"10.1016\/j.it.2025.01.006_bb0390","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1093\/rheumatology\/keaa692","article-title":"Incidence of extra-articular manifestations in ankylosing spondylitis, psoriatic arthritis and undifferentiated spondyloarthritis: results from a national register-based cohort study","volume":"60","author":"Bengtsson","year":"2021","journal-title":"Rheumatology"},{"key":"10.1016\/j.it.2025.01.006_bb0395","doi-asserted-by":"crossref","DOI":"10.1111\/febs.17124","article-title":"A guide to germ-free and gnotobiotic mouse technology to study health and disease","author":"Jans","year":"2024","journal-title":"FEBS J."},{"key":"10.1016\/j.it.2025.01.006_bb0400","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/apt.17049","article-title":"Review article: the future of microbiome-based therapeutics","volume":"56","author":"Gulliver","year":"2022","journal-title":"Aliment. Pharmacol. 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Rheumatol."},{"key":"10.1016\/j.it.2025.01.006_bb0415","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1002\/art.40490","article-title":"Modulation of inflammatory arthritis in mice by gut microbiota through mucosal inflammation and autoantibody generation","volume":"70","author":"Jubair","year":"2018","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.it.2025.01.006_bb0420","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1089\/jir.2016.0057","article-title":"Lactobacillus salivarius isolated from patients with rheumatoid arthritis suppresses collagen-induced arthritis and increases Treg frequency in mice","volume":"36","author":"Liu","year":"2016","journal-title":"J. Interferon. 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Immunopharmacol."},{"key":"10.1016\/j.it.2025.01.006_bb0450","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1038\/nprot.2007.173","article-title":"Collagen-induced arthritis","volume":"2","author":"Brand","year":"2007","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.it.2025.01.006_bb0455","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2020.102913","article-title":"Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells","volume":"58","author":"Takahashi","year":"2020","journal-title":"EBioMedicine"},{"key":"10.1016\/j.it.2025.01.006_bb0460","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1038\/s41551-024-01190-x","article-title":"A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice","volume":"8","author":"Cao","year":"2024","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.it.2025.01.006_bb0465","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/s41368-024-00315-x","article-title":"Caspase-11 mediated inflammasome activation in macrophages by systemic infection of A. actinomycetemcomitans exacerbates arthritis","volume":"16","author":"Okano","year":"2024","journal-title":"Int. J. Oral Sci."},{"key":"10.1016\/j.it.2025.01.006_bb0470","article-title":"Standardized protocol and outcome measurements for the collagen antibody-induced arthritis mouse model","volume":"3","author":"Maleitzke","year":"2022","journal-title":"STAR Protoc."},{"key":"10.1016\/j.it.2025.01.006_bb0475","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1128\/iai.26.3.791-794.1979","article-title":"Susceptibility to adjuvant-induced arthritis among germfree, specific-pathogen-free, and conventional rats","volume":"26","author":"Kohashi","year":"1979","journal-title":"Infect. 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Immunol."},{"key":"10.1016\/j.it.2025.01.006_bb0485","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1186\/s40168-019-0719-1","article-title":"A single bacterium restores the microbiome dysbiosis to protect bones from destruction in a rat model of rheumatoid arthritis","volume":"7","author":"Pan","year":"2019","journal-title":"Microbiome"},{"key":"10.1016\/j.it.2025.01.006_bb0490","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s13075-023-03069-9","article-title":"Increased gut permeability and intestinal inflammation precede arthritis onset in the adjuvant-induced model of arthritis","volume":"25","author":"Hecquet","year":"2023","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.it.2025.01.006_bb0495","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1007\/s00011-006-6026-x","article-title":"Manipulation of the induction of adjuvant arthritis in Sprague\u2013Dawley rats","volume":"55","author":"Cai","year":"2006","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.it.2025.01.006_bb0500","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1084\/jem.191.2.313","article-title":"Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice","volume":"191","author":"Horai","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.it.2025.01.006_bb0505","doi-asserted-by":"crossref","first-page":"7464","DOI":"10.1038\/ncomms8464","article-title":"IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2+V\u03b36+ \u03b3\u03b4 T cells","volume":"6","author":"Akitsu","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.it.2025.01.006_bb0510","doi-asserted-by":"crossref","first-page":"5986","DOI":"10.1073\/pnas.1035999100","article-title":"IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist","volume":"100","author":"Nakae","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.it.2025.01.006_bb0515","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1172\/JCI32639","article-title":"Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis","volume":"118","author":"Abdollahi-Roodsaz","year":"2008","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.it.2025.01.006_bb0520","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.immuni.2010.06.001","article-title":"Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells","volume":"32","author":"Wu","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.it.2025.01.006_bb0525","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.immuni.2016.03.013","article-title":"Gut microbiota drive autoimmune arthritis by promoting differentiation and migration of Peyer\u2019s patch T follicular helper cells","volume":"44","author":"Teng","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.it.2025.01.006_bb0530","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3389\/fimmu.2016.00213","article-title":"K\/BxN serum-transfer arthritis as a model for human inflammatory arthritis","volume":"7","author":"Christensen","year":"2016","journal-title":"Front. Immunol."},{"key":"10.1016\/j.it.2025.01.006_bb0535","first-page":"2780","article-title":"ZAP-70 genotype disrupts the relationship between microbiota and host, leading to spondyloarthritis and ileitis in SKG mice. Arthritis","volume":"66","author":"Rehaume","year":"2014","journal-title":"Rheumatol"},{"key":"10.1016\/j.it.2025.01.006_bb0540","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1002\/art.39783","article-title":"Dysbiosis contributes to arthritis development via activation of autoreactive T cells in the intestine","volume":"68","author":"Maeda","year":"2016","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.it.2025.01.006_bb0545","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/ar811","article-title":"SKG mice, a new genetic model of rheumatoid arthritis","volume":"5","author":"Sakaguchi","year":"2003","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.it.2025.01.006_bb0550","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1084\/jem.180.6.2359","article-title":"The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats","volume":"180","author":"Taurog","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.it.2025.01.006_bb0555","article-title":"HLA-B27 and human \u03b22-microglobulin affect the gut microbiota of transgenic rats","volume":"9","author":"Lin","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.it.2025.01.006_bb0560","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1002\/art.21740","article-title":"Additional human beta2-microglobulin curbs HLA-B27 misfolding and promotes arthritis and spondylitis without colitis in male HLA-B27-transgenic rats","volume":"54","author":"Tran","year":"2006","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.it.2025.01.006_bb0565","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/S0198-8859(00)00122-1","article-title":"Germ-free mice do not develop ankylosing enthesopathy, a spontaneous joint disease","volume":"61","author":"\u0158eh\u00e1kov\u00e1","year":"2000","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.it.2025.01.006_bb0570","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.humimm.2008.08.296","article-title":"Commensal intestinal bacterial strains trigger ankylosing enthesopathy of the ankle in inbred B10.BR (H-2k) male mice","volume":"69","author":"\u0160inkorov\u00e1","year":"2008","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.it.2025.01.006_bb0575","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1038\/ng.874","article-title":"A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis","volume":"43","author":"Matmati","year":"2011","journal-title":"Nat. Genet."},{"key":"10.1016\/j.it.2025.01.006_bb0580","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1038\/s41556-019-0324-3","article-title":"A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain","volume":"21","author":"Polykratis","year":"2019","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.it.2025.01.006_bb0585","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1136\/gutjnl-2015-309333","article-title":"Dysbiotic gut microbiota causes transmissible Crohn\u2019s disease-like ileitis independent of failure in antimicrobial defence","volume":"65","author":"Schaubeck","year":"2016","journal-title":"Gut"},{"key":"10.1016\/j.it.2025.01.006_bb0590","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.932393","article-title":"Cytokine competent gut\u2013joint migratory T cells contribute to inflammation in the joint","volume":"13","author":"Lefferts","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.it.2025.01.006_bb0595","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1136\/annrheumdis-2013-203643","article-title":"Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells","volume":"73","author":"Jacques","year":"2014","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.it.2025.01.006_bb0600","doi-asserted-by":"crossref","first-page":"469","DOI":"10.4103\/0019-5154.190105","article-title":"Anti-inflammatory and immunomodulatory effects of antibiotics and their use in dermatology","volume":"61","author":"Pradhan","year":"2016","journal-title":"Indian J. Dermatol."},{"key":"10.1016\/j.it.2025.01.006_bb0605","doi-asserted-by":"crossref","first-page":"742","DOI":"10.3390\/antibiotics13080742","article-title":"Immunomodulatory effects and protection in sepsis by the antibiotic moxifloxacin","volume":"13","author":"Velho","year":"2024","journal-title":"Antibiotics"},{"key":"10.1016\/j.it.2025.01.006_bb0610","doi-asserted-by":"crossref","first-page":"4119","DOI":"10.1126\/sciadv.adp4119","article-title":"Antibiotics damage the colonic mucus barrier in a microbiota-independent manner","volume":"10","author":"Sawaed","year":"2024","journal-title":"Sci. Adv."},{"key":"10.1016\/j.it.2025.01.006_bb0615","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.7150\/ijbs.79430","article-title":"The role of gut microbiota in T cell immunity and immune mediated disorders","volume":"19","author":"Shim","year":"2023","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.it.2025.01.006_bb0620","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1080\/19490976.2017.1299311","article-title":"Regulation of humoral immunity by gut microbial products","volume":"8","author":"Kim","year":"2017","journal-title":"Gut Microbes"},{"key":"10.1016\/j.it.2025.01.006_bb0625","doi-asserted-by":"crossref","first-page":"6686","DOI":"10.1038\/s41467-021-26963-9","article-title":"A standardized gnotobiotic mouse model harboring a minimal 15-member mouse gut microbiota recapitulates SOPF\/SPF phenotypes","volume":"12","author":"Darnaud","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.it.2025.01.006_bb0630","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3934\/microbiol.2024007","article-title":"What we need to know about the germ-free animal models","volume":"10","author":"Aghighi","year":"2024","journal-title":"AIMS Microbiol."},{"key":"10.1016\/j.it.2025.01.006_bb0635","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.4014\/jmb.1501.01039","article-title":"Use of germ-free animal models in microbiota-related research","volume":"25","author":"Al-Asmakh","year":"2015","journal-title":"J. Microbiol. Biotechnol."},{"key":"10.1016\/j.it.2025.01.006_bb0640","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/s40168-017-0306-2","article-title":"Stable engraftment of human microbiota into mice with a single oral gavage following antibiotic conditioning","volume":"5","author":"Staley","year":"2017","journal-title":"Microbiome"},{"key":"10.1016\/j.it.2025.01.006_bb0645","doi-asserted-by":"crossref","first-page":"7805","DOI":"10.1038\/s41598-020-64703-z","article-title":"Human microbiota-transplanted C57BL\/6 mice and offspring display reduced establishment of key bacteria and reduced immune stimulation compared to mouse microbiota-transplantation","volume":"10","author":"Lundberg","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.it.2025.01.006_bb0650","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1038\/s42003-020-01477-0","article-title":"Differential longitudinal establishment of human fecal bacterial communities in germ-free porcine and murine models","volume":"3","author":"Aluthge","year":"2020","journal-title":"Commun. 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