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Invest."},{"key":"10.1016\/j.it.2026.08.014_bb0420","doi-asserted-by":"crossref","first-page":"6052","DOI":"10.1182\/blood-2012-01-406967","article-title":"DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues","volume":"119","author":"Poulin","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.it.2026.08.014_bb0425","doi-asserted-by":"crossref","first-page":"3146","DOI":"10.3389\/fimmu.2019.03146","article-title":"DNGR-1, a dendritic cell-specific sensor of tissue damage that dually modulates immunity and inflammation","volume":"10","author":"Cueto","year":"2019","journal-title":"Front. 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Med."},{"key":"10.1016\/j.it.2026.08.014_bb0460","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/s41571-024-00859-1","article-title":"Dendritic cells as orchestrators of anticancer immunity and immunotherapy","volume":"21","author":"Heras-Murillo","year":"2024","journal-title":"Nat. Rev. Clin. 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Res."},{"key":"10.1016\/j.it.2026.08.014_bb0515","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1016\/j.immuni.2022.05.013","article-title":"Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication","volume":"55","author":"Gargaro","year":"2022","journal-title":"Immunity"},{"key":"10.1016\/j.it.2026.08.014_bb0520","doi-asserted-by":"crossref","DOI":"10.1172\/JCI192811","article-title":"Type 1 classical dendritic cells govern long-term cardiac allograft acceptance","volume":"135","author":"Owen","year":"2025","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.it.2026.08.014_bb0525","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1038\/nri1845","article-title":"Dendritic cells in a mature age","volume":"6","author":"Reis e Sousa","year":"2006","journal-title":"Nat. Rev. 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Rev."},{"key":"10.1016\/j.it.2026.08.014_bb0545","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0092-8674(00)80059-8","article-title":"CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs","volume":"99","author":"Forster","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.it.2026.08.014_bb0550","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1038\/nri2297","article-title":"CCR7 and its ligands: balancing immunity and tolerance","volume":"8","author":"Forster","year":"2008","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.it.2026.08.014_bb0555","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/nri.2016.116","article-title":"Dendritic cell migration in health and disease","volume":"17","author":"Worbs","year":"2017","journal-title":"Nat. Rev. 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Med."},{"key":"10.1016\/j.it.2026.08.014_bb0585","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/nature06110","article-title":"Loss of integrin \u03b1v\u03b28 on dendritic cells causes autoimmunity and colitis in mice","volume":"449","author":"Travis","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.it.2026.08.014_bb0590","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2025.116150","article-title":"Lipid nanoparticles as a tool to dissect dendritic cell maturation pathways","volume":"44","author":"Rennen","year":"2025","journal-title":"Cell Rep."},{"key":"10.1016\/j.it.2026.08.014_bb0595","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.immuni.2015.03.003","article-title":"Homeostatic NF-\u03baB signaling in steady-state migratory dendritic cells regulates immune homeostasis and tolerance","volume":"42","author":"Baratin","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.it.2026.08.014_bb0600","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.immuni.2011.05.013","article-title":"The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity","volume":"35","author":"Kool","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.it.2026.08.014_bb0605","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.immuni.2016.10.008","article-title":"Immunomodulatory functions of BTLA and HVEM govern induction of extrathymic regulatory T cells and tolerance by dendritic cells","volume":"45","author":"Jones","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.it.2026.08.014_bb0610","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1615\/CritRevImmunol.2018026790","article-title":"Immunomodulatory bonds of the partnership between dendritic cells and T cells","volume":"38","author":"Bourque","year":"2018","journal-title":"Crit. Rev. Immunol."},{"key":"10.1016\/j.it.2026.08.014_bb0615","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1038\/s41423-024-01133-1","article-title":"CD4+ T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors","volume":"21","author":"Lei","year":"2024","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.it.2026.08.014_bb0620","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1038\/s41577-018-0044-0","article-title":"CD4+ T cell help in cancer immunology and immunotherapy","volume":"18","author":"Borst","year":"2018","journal-title":"Nat. Rev. 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Rev. Immunol."},{"key":"10.1016\/j.it.2026.08.014_bb0695","first-page":"167","article-title":"Tumour hypoxia in driving genomic instability and tumour evolution","volume":"25","author":"Suvac","year":"2025","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.it.2026.08.014_bb0700","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1038\/s41590-024-01896-9","article-title":"T cell dysfunction and therapeutic intervention in cancer","volume":"25","author":"Zebley","year":"2024","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.it.2026.08.014_bb0705","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1038\/s41590-024-02065-8","article-title":"Cholesterol mobilization regulates dendritic cell maturation and the immunogenic response to cancer","volume":"26","author":"Belabed","year":"2025","journal-title":"Nat. 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