{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:49:33Z","timestamp":1790790573741,"version":"4.1.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaacap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Child &amp; Adolescent Psychiatry"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.jaac.2011.01.021","type":"journal-article","created":{"date-parts":[[2011,4,25]],"date-time":"2011-04-25T05:50:06Z","timestamp":1303710606000},"page":"543-553","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":281,"title":["Does ADHD Predict Substance-Use Disorders? A 10-Year Follow-up Study of Young Adults With ADHD"],"prefix":"10.1016","volume":"50","author":[{"given":"Timothy E.","family":"Wilens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MaryKate","family":"Martelon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gagan","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clancey","family":"Bateman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronna","family":"Fried","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carter","family":"Petty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Biederman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaac.2011.01.021_bib1","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1001\/archpsyc.64.5.566","article-title":"Prevalence, correlates, disability, and comorbidity of DSM-IV drug abuse and dependence in the United States: results from the national epidemiologic survey on alcohol and related conditions","volume":"64","author":"Compton","year":"2007","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib2","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1097\/00004583-199509000-00022","article-title":"Longitudinally predicting late adolescent and young adult drug use: childhood and adolescent precursors","volume":"34","author":"Brook","year":"1995","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1080\/10550490050172191","article-title":"Age of onset as a discriminator between alcoholic subtypes in a treatment-seeking outpatient population","volume":"9","author":"Johnson","year":"2000","journal-title":"Am J Addict"},{"key":"10.1016\/j.jaac.2011.01.021_bib4","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1097\/00004583-199509000-00021","article-title":"Adolescent psychopathology: IV","volume":"34","author":"Lewinsohn","year":"1995","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib5","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1097\/00004583-199612000-00009","article-title":"Young adult drug use and delinquency: childhood antecedents and adolescent mediators","volume":"35","author":"Brook","year":"1996","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib6","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1097\/00004583-199906000-00016","article-title":"Psychiatric comorbidity among adolescents with substance use disorders: findings from the MECA study","volume":"38","author":"Kandel","year":"1999","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib7","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1097\/01.chi.0000159135.33706.37","article-title":"Practice parameter for the assessment and treatment of children and adolescents with substance use disorders","volume":"44","author":"Bukstein","year":"2005","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib8","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1176\/ajp.2007.164.6.942","article-title":"The worldwide prevalence of ADHD: a systematic review and meta-regression analysis","volume":"164","author":"Polanczyk","year":"2007","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib9","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1176\/ajp.2006.163.4.716","article-title":"The prevalence and correlates of adult ADHD in the United States: Results from the national comorbidity survey replication","volume":"163","author":"Kessler","year":"2006","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib10","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1097\/00004583-199007000-00007","article-title":"The adolescent outcome of hyperactive children diagnosed by research criteria: I","volume":"29","author":"Barkley","year":"1990","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib11","first-page":"42","article-title":"The course and outcome of ADHD","volume":"11","author":"Mick","year":"2004","journal-title":"Prim Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib12","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1001\/archpsyc.1993.01820190067007","article-title":"Adult outcome of hyperactive boys: educational achievement, occupational rank, and psychiatric status","volume":"50","author":"Mannuzza","year":"1993","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib13","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/00004583-199701000-00013","article-title":"Is ADHD a risk for psychoactive substance use disorder?","volume":"36","author":"Biederman","year":"1997","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib14","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1037\/0021-843X.112.3.497","article-title":"Childhood predictors of adolescent substance use in a longitudinal study of children with ADHD","volume":"112","author":"Molina","year":"2003","journal-title":"J Abnorm Psychol"},{"key":"10.1016\/j.jaac.2011.01.021_bib15","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1177\/070674378603100614","article-title":"Controlled prospective fifteen year follow-up of hyperactives as adults: Non-medical drug and alcohol use and anti-social behaviour","volume":"31","author":"Hechtman","year":"1986","journal-title":"Can J Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib16","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1176\/ajp.155.4.493","article-title":"Adult psychiatric status of hyperactive boys grown up","volume":"155","author":"Mannuzza","year":"1998","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib17","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1097\/chi.0b013e3180686d96","article-title":"Delinquent behavior and emerging substance use in the MTA at 36 months: prevalence, course, and treatment effects","volume":"46","author":"Molina","year":"2007","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib18","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1176\/ajp.139.6.795","article-title":"A prospective study of delinquency in 110 adolescent boys with attention deficit disorder and 88 normal adolescent boys","volume":"139","author":"Satterfield","year":"1982","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib19","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1111\/j.1360-0443.2007.01850.x","article-title":"Is attention-deficit\/hyperactivity disorder associated with illicit substance use disorders in male adolescents?","volume":"102","author":"Szobot","year":"2007","journal-title":"Addiction"},{"key":"10.1016\/j.jaac.2011.01.021_bib20","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1207\/S15374424jccp280304","article-title":"Developmental aspects of delinquency and internalizing problems and their association with persistent juvenile substance use between ages 7 and 18","volume":"28","author":"Loeber","year":"1999","journal-title":"J Clin Child Psychol"},{"key":"10.1016\/j.jaac.2011.01.021_bib21","doi-asserted-by":"crossref","first-page":"673","DOI":"10.3109\/00048679309075830","article-title":"Conduct problems and attention deficit behaviour in middle childhood and cannabis use by age 15","volume":"27","author":"Fergusson","year":"1993","journal-title":"Aust N Z J Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib22","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1001\/archpediatrics.2010.180","article-title":"Association between attention-deficit\/hyperactivity disorder in adolescence and substance use disorders in adulthood","volume":"164","author":"Brook","year":"2010","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.jaac.2011.01.021_bib23","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1093\/oxfordjournals.aje.a116411","article-title":"The risk of alcohol abuse and dependence in adulthood: the association with educational level","volume":"135","author":"Crum","year":"1992","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jaac.2011.01.021_bib24","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/S1054-139X(01)00395-0","article-title":"Drug use and neurobehavioral, respiratory, and cognitive problems: precursors and mediators","volume":"30","author":"Brook","year":"2002","journal-title":"J Adolesc Health"},{"key":"10.1016\/j.jaac.2011.01.021_bib25","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1176\/appi.ajp.160.6.1078","article-title":"Neurobehavioral disinhibition in childhood predicts early age at onset of substance use disorder","volume":"160","author":"Tarter","year":"2003","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib26","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1017\/S0033291705006410","article-title":"Young adult outcome of attention deficit hyperactivity disorder: a controlled 10 year follow-up study","volume":"36","author":"Biederman","year":"2006","journal-title":"Psychol Med"},{"key":"10.1016\/j.jaac.2011.01.021_bib27","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1176\/appi.ajp.2009.09050736","article-title":"Adult psychiatric outcomes of girls with attention deficit hyperactivity disorder: 11-year follow-up in a longitudinal case-control study","volume":"167","author":"Biederman","year":"2010","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib28","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1176\/appi.ps.53.9.1103","article-title":"Correlates of ADHD among children in pediatric and psychiatric clinics","volume":"53","author":"Busch","year":"2002","journal-title":"Psychiatr Serv"},{"key":"10.1016\/j.jaac.2011.01.021_bib29","series-title":"Schedule for Affective Disorder and Schizophrenia for School-Age Children Epidemiologic Version","author":"Orvaschel","year":"1994"},{"key":"10.1016\/j.jaac.2011.01.021_bib30","series-title":"Structured Clinical Interview for DSM-IV Axis I Disorders","author":"First","year":"1997"},{"key":"10.1016\/j.jaac.2011.01.021_bib31","series-title":"Structured Clinical Interview for DSM-III-R-Non-Patient Edition (SCID-NP, Version 1.0)","author":"Spitzer","year":"1990"},{"key":"10.1016\/j.jaac.2011.01.021_bib32","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1001\/archpsyc.1982.04290100031006","article-title":"A family study of schizoaffective, bipolar I, bipolar II, unipolar, and normal control probands","volume":"39","author":"Gershon","year":"1982","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib33","series-title":"Four Factor Index of Social Status","author":"Hollingshead","year":"1975"},{"key":"10.1016\/j.jaac.2011.01.021_bib34","series-title":"Assessment of Adaptive Functioning in Children: A Review of Existing Measures Suitable for Epidemiological and Clinical Services Research","author":"Orvaschel","year":"1984"},{"key":"10.1016\/j.jaac.2011.01.021_bib35","series-title":"Manual for the Family Environment Scale","author":"Moos","year":"1974"},{"key":"10.1016\/j.jaac.2011.01.021_bib36","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1097\/00004583-199712000-00016","article-title":"Correspondence between DSM-III-R and DSM-IV attention deficit hyperactivity disorder (ADHD)","volume":"36","author":"Biederman","year":"1997","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib37","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1097\/00005053-199708000-00001","article-title":"Attention deficit hyperactivity disorder (ADHD) is associated with early onset substance use disorders","volume":"185","author":"Wilens","year":"1997","journal-title":"J Nerv Ment Dis"},{"key":"10.1016\/j.jaac.2011.01.021_bib38","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0376-8716(98)00016-7","article-title":"Substance-dependent, conduct-disordered adolescent males: severity of diagnosis predicts 2-year outcome","volume":"49","author":"Crowley","year":"1998","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.jaac.2011.01.021_bib39","first-page":"19","article-title":"Substance abuse in adolescents: diagnostic issues derived from studies of attention deficit disorder with hyperactivity","volume":"77","author":"Loney","year":"1988","journal-title":"NIDA Res Monogr"},{"key":"10.1016\/j.jaac.2011.01.021_bib40","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1176\/ajp.152.11.1652","article-title":"Psychoactive substance use disorders in adults with attention deficit hyperactivity disorder (ADHD): effects of ADHD and psychiatric comorbidity","volume":"152","author":"Biederman","year":"1995","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib41","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.drugalcdep.2007.12.016","article-title":"Further evidence of an association between adolescent bipolar disorder with smoking and substance use disorders: a controlled study","volume":"95","author":"Wilens","year":"2008","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.jaac.2011.01.021_bib42","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.drugalcdep.2006.02.009","article-title":"Memory functioning in polysubstance dependent women","volume":"84","author":"Medina","year":"2006","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.jaac.2011.01.021_bib43","doi-asserted-by":"crossref","first-page":"99","DOI":"10.2174\/1874473710801010099","article-title":"The influence of marijuana use on neurocognitive functioning in adolescents","volume":"1","author":"Schweinsburg","year":"2008","journal-title":"Curr Drug Abuse Rev"},{"key":"10.1016\/j.jaac.2011.01.021_bib44","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1111\/j.1530-0277.2008.00859.x","article-title":"Changes in the episodic memory and executive functions of abstinent and relapsed alcoholics over a 6-month period","volume":"33","author":"Pitel","year":"2009","journal-title":"Alcohol Clin Exp Res"},{"key":"10.1016\/j.jaac.2011.01.021_bib45","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jaac.2010.11.010","article-title":"Do executive function deficits predict later substance use disorders among adolescents and young adults?","volume":"50","author":"Wilens","year":"2011","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib46","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1176\/appi.ajp.2007.07091486","article-title":"Stimulant therapy and risk for subsequent substance use disorders in male adults with ADHD: a naturalistic controlled 10-year follow-up study","volume":"165","author":"Biederman","year":"2008","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib47","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1001\/archpedi.162.10.916","article-title":"Effect of prior stimulant treatment for attention-deficit\/hyperactivity disorder on subsequent risk for cigarette smoking and alcohol and drug use disorders in adolescents","volume":"162","author":"Wilens","year":"2008","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.jaac.2011.01.021_bib48","doi-asserted-by":"crossref","first-page":"e20","DOI":"10.1542\/peds.104.2.e20","article-title":"Pharmacotherapy of attention-deficit\/hyperactivity disorder reduces risk for substance use disorder","volume":"104","author":"Biederman","year":"1999","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaac.2011.01.021_bib49","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1176\/appi.ajp.2007.07030419","article-title":"Familial risk analyses of attention deficit hyperactivity disorder and substance use disorders","volume":"165","author":"Biederman","year":"2008","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib50","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/(SICI)1096-8628(19960920)67:5<473::AID-AJMG6>3.0.CO;2-L","article-title":"Genetic influences on DSM-III-R drug abuse and dependence: a study of 3,372 twin pairs","volume":"67","author":"Tsuang","year":"1996","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.jaac.2011.01.021_bib51","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1001\/archpsyc.1992.01820080007002","article-title":"Types of alcoholics, 1: evidence for an empirically derived typology based on indicators of vulnerability and severity","volume":"49","author":"Babor","year":"1992","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib52","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1001\/archpsyc.1981.01780330019001","article-title":"Inheritance of alcohol abuse: cross-fostering analysis of adopted men","volume":"38","author":"Cloninger","year":"1981","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib53","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1001\/archpsyc.1990.01810160020003","article-title":"Clinical importance of age at onset in type 1 and type 2 primary alcoholics","volume":"47","author":"Irwin","year":"1990","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jaac.2011.01.021_bib54","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1001\/archpedi.162.10.916","article-title":"Impact of prior stimulant treatment for attention-deficit hyperactivity disorder in the subsequent risk for cigarette smoking, alcohol, and drug use disorders in adolescent girls","volume":"162","author":"Wilens","year":"2008","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.jaac.2011.01.021_bib55","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1089\/cap.2005.15.742","article-title":"Assessing cannabis use in adolescents and young adults: what do urine screen and parental report tell you?","volume":"15","author":"Gignac","year":"2005","journal-title":"J Child Adolesc Psychopharmacol"},{"key":"10.1016\/j.jaac.2011.01.021_bib56","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1136\/bmj.316.7139.1236","article-title":"What's wrong with Bonferroni adjustments","volume":"316","author":"Perneger","year":"1998","journal-title":"BMJ"},{"key":"10.1016\/j.jaac.2011.01.021_bib57","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/00001648-199001000-00010","article-title":"No adjustments are needed for multiple comparisons","volume":"1","author":"Rothman","year":"1990","journal-title":"Epidemiology"}],"container-title":["Journal of the American Academy of Child &amp; Adolescent Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890856711000967?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890856711000967?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T14:22:57Z","timestamp":1760192577000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890856711000967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":57,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0890856711000967"],"URL":"https:\/\/doi.org\/10.1016\/j.jaac.2011.01.021","relation":{},"ISSN":["0890-8567"],"issn-type":[{"value":"0890-8567","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Does ADHD Predict Substance-Use Disorders? A 10-Year Follow-up Study of Young Adults With ADHD","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Child & Adolescent Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaac.2011.01.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}