{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T02:08:30Z","timestamp":1781057310289,"version":"3.54.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American Academy of Child & Adolescent Psychiatry"],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1016\/j.jaac.2012.07.001","type":"journal-article","created":{"date-parts":[[2012,7,31]],"date-time":"2012-07-31T01:34:39Z","timestamp":1343698479000},"page":"867-878","source":"Crossref","is-referenced-by-count":56,"title":["Treatment Moderators and Predictors of Outcome in the Treatment of Early Age Mania (TEAM) Study"],"prefix":"10.1016","volume":"51","author":[{"given":"Benedetto","family":"Vitiello","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Riddle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gayane","family":"Yenokyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Axelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen D.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paramjit","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John T.","family":"Walkup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Luby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris","family":"Birmaher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neal D.","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham","family":"Emslie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adelaide","family":"Robb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Tillman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaac.2012.07.001_bib1","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/01.chi.0000242240.69678.c4","article-title":"Practice parameter for the assessment and treatment of children and adolescents with bipolar disorder","volume":"46","author":"McClellan","year":"2007","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2012.07.001_bib2","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/j.jaac.2011.05.011","article-title":"Pharmacologic treatments for pediatric bipolar disorder: a review and meta-analysis","volume":"50","author":"Liu","year":"2011","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2012.07.001_bib3","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1111\/j.1399-5618.2010.00798.x","article-title":"Antipsychotic and mood stabilizer efficacy and tolerability in pediatric and adult patients with bipolar I mania: a comparative analysis of acute, randomized, placebo-controlled trials","volume":"12","author":"Correll","year":"2010","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.jaac.2012.07.001_bib4","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1001\/archpsyc.59.10.877","article-title":"Mediators and moderators of treatment effects in randomized clinical trials","volume":"59","author":"Kraemer","year":"2002","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jaac.2012.07.001_bib5","doi-asserted-by":"crossref","first-page":"296","DOI":"10.4088\/JCP.09m05514yel","article-title":"Clinical features associated with poor pharmacologic adherence in bipolar disorder: results from the STEP-BD study","volume":"71","author":"Perlis","year":"2010","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.jaac.2012.07.001_bib6","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1176\/ajp.2007.164.4.582","article-title":"Twelve-month outcome of adolescents with bipolar disorder following first hospitalization for a manic or mixed episode","volume":"164","author":"DelBello","year":"2007","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2012.07.001_bib7","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1176\/appi.ajp.2009.08101569","article-title":"Four-year longitudinal course of children and adolescents with bipolar spectrum disorders: the Course and Outcome of Bipolar Youth (COBY) study","volume":"166","author":"Birmaher","year":"2009","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2012.07.001_bib8","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.psychres.2009.01.022","article-title":"Pharmacological response in juvenile bipolar disorder subtypes: a naturalistic retrospective examination","volume":"177","author":"Masi","year":"2010","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.jaac.2012.07.001_bib9","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/CHI.0b013e31819c55ec","article-title":"Divalproex treatment effect not influenced by age (10\u201313 versus 14\u201317) in placebo controlled trial (4 weeks) in mania","volume":"48","author":"Wagner","year":"2009","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2012.07.001_bib10","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1001\/archgenpsychiatry.2011.1508","article-title":"A randomized controlled trial of risperidone, lithium, or divalproex for initial treatment of bipolar I disorder, manic or mixed phase, in children and adolescents","volume":"69","author":"Geller","year":"2012","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jaac.2012.07.001_bib11","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/S0140-6736(11)60873-8","article-title":"Comparative effectiveness and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysis","volume":"378","author":"Cipriani","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.jaac.2012.07.001_bib12","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1176\/appi.ajp.159.6.927","article-title":"Two-year prospective follow-up of children with a prepubertal and early adolescent bipolar disorder phenotype","volume":"159","author":"Geller","year":"2002","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2012.07.001_bib13","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0165-1781(97)00123-6","article-title":"Modification of the Clinical Global Impressions (CGI) Scale for use in bipolar illness (BP): the CGI-BP","volume":"73","author":"Spearing","year":"1997","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.jaac.2012.07.001_bib14","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1089\/104454603322724850","article-title":"A preliminary study of the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children mania rating scale for children and adolescents","volume":"13","author":"Axelson","year":"2003","journal-title":"J Child Adolesc Psychopharmacol"},{"key":"10.1016\/j.jaac.2012.07.001_bib15","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1542\/peds.66.6.918","article-title":"Adolescents' self-assessment of sexual maturation","volume":"66","author":"Duke","year":"1980","journal-title":"Pediatrics"},{"key":"10.1016\/j.jaac.2012.07.001_bib16","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1001\/archpsyc.1977.01770220111013","article-title":"The family history method using diagnostic criteria","volume":"34","author":"Andreasen","year":"1977","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jaac.2012.07.001_bib17","series-title":"Psychosocial Schedule for School Age Children\u2014Revised","author":"Puigh-Antich","year":"1986"},{"key":"10.1016\/j.jaac.2012.07.001_bib18","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1097\/00004583-200012000-00018","article-title":"Psychosocial functioning in a prepubertal and early adolescent bipolar disorder phenotype","volume":"39","author":"Geller","year":"2000","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2012.07.001_bib19","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/S0197-2456(99)00022-7","article-title":"Worst-rank score analysis with informatively missing observations in clinical trials","volume":"20","author":"Lachin","year":"1999","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.jaac.2012.07.001_bib20","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1093\/aje\/kwh090","article-title":"A modified Poisson regression approach to prospective studies with binary data","volume":"159","author":"Zou","year":"2004","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jaac.2012.07.001_bib21","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1111\/1467-9280.00287","article-title":"Contrasts and correlations in effect-size estimation","volume":"11","author":"Rosnow","year":"2000","journal-title":"Psychol Sci"},{"key":"10.1016\/j.jaac.2012.07.001_bib22","doi-asserted-by":"crossref","first-page":"383","DOI":"10.3109\/00952990.2011.600386","article-title":"Modeling site effects in the design and analysis of multi-site trials","volume":"37","author":"Feaster","year":"2011","journal-title":"Am J Drug Alcohol Abuse"},{"key":"10.1016\/j.jaac.2012.07.001_bib23","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1093\/oxfordjournals.schbul.a033474","article-title":"Pitfalls of multisite randomized clinical trials of efficacy and effectiveness","volume":"26","author":"Kraemer","year":"2000","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.jaac.2012.07.001_bib24","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1037\/a0014834","article-title":"Sources of site differences in the efficacy of a multisite clinical trial: the Treatment of SSRI-Resistant Depression in Adolescents","volume":"77","author":"Spirito","year":"2009","journal-title":"J Consult Clin Psychol"},{"key":"10.1016\/j.jaac.2012.07.001_bib25","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1176\/appi.ajp.2010.10050766","article-title":"Severe mood dysregulation, irritability, and the diagnostic boundaries of bipolar disorder in youths","volume":"168","author":"Leibenluft","year":"2011","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2012.07.001_bib26","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jad.2006.01.020","article-title":"Psychiatrist effects in the psychopharmacological treatment of depression","volume":"92","author":"McKay","year":"2006","journal-title":"J Affect Dis"}],"container-title":["Journal of the American Academy of Child & Adolescent Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890856712004972?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890856712004972?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T22:19:30Z","timestamp":1643062770000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890856712004972"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":26,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["S0890856712004972"],"URL":"https:\/\/doi.org\/10.1016\/j.jaac.2012.07.001","relation":{},"ISSN":["0890-8567"],"issn-type":[{"value":"0890-8567","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9]]}}}