{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:01:45Z","timestamp":1792173705156,"version":"4.4.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","jaacap.org","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Child & Adolescent Psychiatry"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1016\/j.jaac.2017.10.008","type":"journal-article","created":{"date-parts":[[2017,10,14]],"date-time":"2017-10-14T20:31:49Z","timestamp":1508013109000},"page":"1034-1042.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":89,"title":["Targeted Family Intervention for Complex Cases of Pediatric Obsessive-Compulsive Disorder: A\u00a0Randomized Controlled Trial"],"prefix":"10.1016","volume":"56","author":[{"given":"Tara S.","family":"Peris","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle S.","family":"Rozenman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine A.","family":"Sugar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James T.","family":"McCracken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Piacentini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaac.2017.10.008_bib1","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1080\/15374410701662790","article-title":"Functional impairment in childhood OCD: development and psychometrics properties of the Child Obsessive-Compulsive Impact Scale\u2212Revised (COIS-R)","volume":"36","author":"Piacentini","year":"2007","journal-title":"J\u00a0Clin Child Adolesc Psychol"},{"key":"10.1016\/j.jaac.2017.10.008_bib2","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1001\/archpsyc.55.1.56","article-title":"The risk for early-adulthood anxiety and depressive disorders in adolescents with anxiety and depressive disorders","volume":"55","author":"Pine","year":"1998","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jaac.2017.10.008_bib3","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jaac.2016.12.012","article-title":"A\u00a0multisite study of family functioning impairment in pediatric obsessive-compulsive disorder","volume":"56","author":"Stewart","year":"2017","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2017.10.008_bib4","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1001\/jamapsychiatry.2014.170","article-title":"Family-based treatment of early childhood obsessive-compulsive disorder: the Pediatric Obsessive-Compulsive Disorder Treatment Study for Young Children (POTS Jr)\u2014a randomized clinical trial","volume":"71","author":"Freeman","year":"2014","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jaac.2017.10.008_bib5","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.jaac.2011.09.019","article-title":"Practice parameter for the assessment and treatment of children and adolescents with obsessive-compulsive disorder","volume":"51","author":"Geller","year":"2012","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2017.10.008_bib6","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1001\/jama.292.16.1969","article-title":"Cognitive-behavior therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder: The Pediatric OCD Treatment Study (POTS) randomized controlled trial","volume":"292","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.jaac.2017.10.008_bib7","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.jaac.2010.06.013","article-title":"Predictors and moderators of treatment outcome in the Pediatric Obsessive Compulsive Treatment Study (POTS I)","volume":"49","author":"Garcia","year":"2010","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2017.10.008_bib8","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1097\/CHI.0b013e3181799ebd","article-title":"Predictors of treatment response in pediatric obsessive-compulsive disorder","volume":"47","author":"Ginsburg","year":"2008","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2017.10.008_bib9","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.janxdis.2009.12.004","article-title":"Predictors of functional impairment in pediatric obsessive-compulsive disorder","volume":"24","author":"Storch","year":"2010","journal-title":"J\u00a0Anxiety Disord"},{"key":"10.1016\/j.jaac.2017.10.008_bib10","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1002\/da.20481","article-title":"Correlates and mediators of functional disability in obsessive-compulsive disorder","volume":"26","author":"Storch","year":"2009","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jaac.2017.10.008_bib11","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1080\/07317100802275447","article-title":"Parental attitudes, beliefs, and responses to childhood obsessive compulsive disorder: the Parental Attitudes and Behaviors Scale","volume":"30","author":"Peris","year":"2008","journal-title":"Child Fam Behav Ther"},{"key":"10.1016\/j.jaac.2017.10.008_bib12","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1037\/a0027084","article-title":"Family factors predict treatment outcome for pediatric obsessive compulsive disorder","volume":"80","author":"Peris","year":"2012","journal-title":"J\u00a0Consult Clin Psychol"},{"key":"10.1016\/j.jaac.2017.10.008_bib13","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1089\/104454603322126359","article-title":"Functional impairment in children and adolescent with obsessive-compulsive disorder","volume":"13","author":"Piacentini","year":"2003","journal-title":"J\u00a0Child Adolesc Psychopharmacol"},{"key":"10.1016\/j.jaac.2017.10.008_bib14","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1080\/15374410701277929","article-title":"Family accommodation in pediatric obsessive-compulsive disorder","volume":"36","author":"Storch","year":"2007","journal-title":"J\u00a0Clin Child Adolesc Psychol"},{"key":"10.1016\/j.jaac.2017.10.008_bib15","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.jocrd.2014.05.003","article-title":"Phenomenological considerations of family accommodation: related clinical characteristics and family factors in pediatric obsessive-compulsive disorder","volume":"3","author":"Wu","year":"2014","journal-title":"J\u00a0Obsessive Compuls Relat Disord"},{"key":"10.1016\/j.jaac.2017.10.008_bib16","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s10802-011-9549-8","article-title":"A\u00a0structural equation analysis of family accommodation in pediatric obsessive-compulsive disorder","volume":"40","author":"Caporino","year":"2012","journal-title":"J\u00a0Abnorm Child Psychol"},{"key":"10.1016\/j.jaac.2017.10.008_bib17","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1002\/da.22251","article-title":"Comparing family accommodation in pediatric obsessive-compulsive disorder, anxiety disorders, and nonanxious children","volume":"31","author":"Lebowitz","year":"2014","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.jaac.2017.10.008_bib18","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1037\/a0012652","article-title":"Decreased family accommodation associated with improved therapy outcome in pediatric obsessive-compulsive disorder","volume":"77","author":"Merlo","year":"2009","journal-title":"J\u00a0Consult Clin Psychol"},{"key":"10.1016\/j.jaac.2017.10.008_bib19","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.jaac.2011.08.003","article-title":"Controlled comparison of family cognitive behavioral therapy and psychoeducation\/relaxation training for child OCD","volume":"50","author":"Piacentini","year":"2011","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2017.10.008_bib20","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.beth.2014.11.001","article-title":"A\u00a0randomized clinical trial of a brief family intervention to reduce accommodation in obsessive-compulsive disorder: a preliminary study","volume":"46","author":"Thompson-Hollands","year":"2015","journal-title":"Behav Ther"},{"key":"10.1016\/j.jaac.2017.10.008_bib21","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1097\/CHI.0b013e3181825a91","article-title":"Correlates of family accommodation of childhood obsessive compulsive disorder: parent, child, and family characteristics","volume":"47","author":"Peris","year":"2008","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2017.10.008_bib22","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1080\/16506070510043732","article-title":"Involving family members in the treatment of OCD","volume":"34","author":"Renshaw","year":"2005","journal-title":"Cogn Behav Ther"},{"key":"10.1016\/j.jaac.2017.10.008_bib23","series-title":"Treatment of Obsessive Compulsive Disorder","author":"Steketee","year":"1993"},{"key":"10.1016\/j.jaac.2017.10.008_bib24","series-title":"Helping Families Manage Childhood OCD: Decreasing Conflict and Increasing Positive Interaction: Therapist Guide","author":"Peris","year":"2016"},{"key":"10.1016\/j.jaac.2017.10.008_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15374416.2012.673162","article-title":"Optimizing treatment for complex cases of childhood obsessive compulsive disorder: a preliminary trial","volume":"42","author":"Peris","year":"2013","journal-title":"J\u00a0Clin Child Adolesc Psychol"},{"key":"10.1016\/j.jaac.2017.10.008_bib26","first-page":"708","article-title":"Defining treatment response and remission in obsessive compulsive disorder: a signal detection analysis of the Children\u2019s Yale-Brown Obsessive Compulsive Scale","volume":"49","author":"Storch","year":"2010","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2017.10.008_bib27","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.psc.2014.05.002","article-title":"Cognitive behavior therapy for obsessive-compulsive and related disorders","volume":"37","author":"Lewin","year":"2014","journal-title":"Psychiatr Clin North Am"},{"key":"10.1016\/j.jaac.2017.10.008_bib28","series-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"2000"},{"key":"10.1016\/j.jaac.2017.10.008_bib29","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1097\/00004583-199706000-00023","article-title":"Children\u2019s Yale-Brown Obsessive Compulsive Scale: reliability and validity","volume":"36","author":"Scahill","year":"1997","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2017.10.008_bib30","series-title":"Cognitive-Behavioral Treatment of Childhood OCD: It\u2019s Only a False Alarm: Therapist Guide","author":"Piacentini","year":"2007"},{"key":"10.1016\/j.jaac.2017.10.008_bib31","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.brat.2014.11.005","article-title":"Effectiveness of cognitive behavior treatment for pediatric obsessive-compulsive disorder: acute outcomes from the Nordic Long-Term OCD Treatment Study (NordLOTS)","volume":"64","author":"Torp","year":"2015","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.jaac.2017.10.008_bib32","series-title":"Anxiety Disorders Interview Schedule for DSM-IV: Parent Version","author":"Silverman","year":"1996"},{"key":"10.1016\/j.jaac.2017.10.008_bib33","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1097\/00004583-200108000-00016","article-title":"Test-retest reliability of anxiety symptoms and diagnoses with Anxiety Disorders Interview Schedule for DSM-IV: Child and Parent Versions","volume":"40","author":"Silverman","year":"2001","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.jaac.2017.10.008_bib34","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.psychres.2004.06.009","article-title":"Psychometric evaluation of the Children\u2019s Yale-Brown Obsessive-Compulsive Scale","volume":"129","author":"Storch","year":"2004","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.jaac.2017.10.008_bib35","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1097\/00005053-199910000-00008","article-title":"Family accommodation of\u00a0obsessive compulsive symptoms: Instrument development and\u00a0assessment of family behavior","volume":"187","author":"Calvocoressi","year":"1999","journal-title":"J\u00a0Nerv Ment Dis"},{"key":"10.1016\/j.jaac.2017.10.008_bib36","series-title":"Family Environment Scale Manual","author":"Moos","year":"1994"},{"key":"10.1016\/j.jaac.2017.10.008_bib37","series-title":"Clinical Global Impressions ECDEU Assessment Manual for Psychopharmacology","author":"Guy","year":"1976"},{"key":"10.1016\/j.jaac.2017.10.008_bib38","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.brat.2009.01.015","article-title":"The diagnostic utility of the Screen for Child Anxiety Related Emotional Disorders\u221271 (SCARED-71)","volume":"47","author":"Bodden","year":"2009","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.jaac.2017.10.008_bib39","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1016\/j.paid.2004.02.014","article-title":"The relationship between child-report, parent self-report, and partner report of perceived parental rearing behaviors and anxiety in children and parents","volume":"37","author":"Bogels","year":"2004","journal-title":"Pers Individ Diff"},{"key":"10.1016\/j.jaac.2017.10.008_bib40","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1007\/BF01664736","article-title":"Family process and child anxiety and aggression: an observational analysis","volume":"24","author":"Dadds","year":"1996","journal-title":"J\u00a0Abnorm Child Psychol"},{"key":"10.1016\/j.jaac.2017.10.008_bib41","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1111\/1467-8624.7402017","article-title":"Parents do matter: trajectories of change in externalizing and internalizing problems in early adolescence","volume":"74","author":"Galambos","year":"2003","journal-title":"Child Dev"},{"key":"10.1016\/j.jaac.2017.10.008_bib42","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1080\/03637750903310360","article-title":"Beyond Baron and Kenny: Statistical Mediation Analysis in the New Millennium","volume":"76","author":"Hayes","year":"2009","journal-title":"Commun Monogr"}],"container-title":["Journal of the American Academy of Child & Adolescent Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890856717317768?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890856717317768?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T03:35:15Z","timestamp":1557372915000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890856717317768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":42,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["S0890856717317768"],"URL":"https:\/\/doi.org\/10.1016\/j.jaac.2017.10.008","relation":{},"ISSN":["0890-8567"],"issn-type":[{"value":"0890-8567","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targeted Family Intervention for Complex Cases of Pediatric Obsessive-Compulsive Disorder: A\u00a0Randomized Controlled Trial","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Child & Adolescent Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaac.2017.10.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a92017 American Academy of Child and Adolescent Psychiatry","name":"copyright","label":"Copyright"}]}}