{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T01:52:13Z","timestamp":1789523533692,"version":"build-2803163510"},"reference-count":48,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100010345","name":"B Braun Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010345","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaacap.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Child & Adolescent Psychiatry"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.jaac.2021.02.014","type":"journal-article","created":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T19:00:44Z","timestamp":1614625244000},"page":"1479-1490","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Adverse Effects of Refeeding on the Plasma Lipidome in\u00a0Young Individuals With Anorexia Nervosa?"],"prefix":"10.1016","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8333-867X","authenticated-orcid":false,"given":"Friederike I.","family":"Tam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8074-7221","authenticated-orcid":false,"given":"Mathias J.","family":"Gerl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Klose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7833-2214","authenticated-orcid":false,"given":"Michal A.","family":"Surma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2864-5578","authenticated-orcid":false,"given":"Joseph A.","family":"King","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8995-6401","authenticated-orcid":false,"given":"Maria","family":"Seidel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1109-7990","authenticated-orcid":false,"given":"Kerstin","family":"Weidner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1873-7081","authenticated-orcid":false,"given":"Veit","family":"Roessner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Simons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2132-4445","authenticated-orcid":false,"given":"Stefan","family":"Ehrlich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaac.2021.02.014_bib1","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1176\/appi.ajp.159.8.1284","article-title":"The outcome of anorexia nervosa in the 20th century","volume":"159","author":"Steinhausen","year":"2002","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2021.02.014_bib2","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s00431-018-3295-7","article-title":"Refeeding in anorexia nervosa","volume":"178","author":"Bargiacchi","year":"2019","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jaac.2021.02.014_bib4","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/eat.22482","article-title":"A\u00a0systematic review of approaches to refeeding in patients with anorexia nervosa","volume":"49","author":"Garber","year":"2016","journal-title":"Int J Eat Disord"},{"key":"10.1016\/j.jaac.2021.02.014_bib5","series-title":"MARSIPAN: Management of Really Sick Patients with Anorexia Nervosa (College Report CR189)","year":"2014"},{"issue":"7 Suppl","key":"10.1016\/j.jaac.2021.02.014_bib6","first-page":"4","article-title":"Practice guideline for the treatment of patients with eating disorders, third edition","volume":"163","year":"2006","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.jaac.2021.02.014_bib7","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/eat.20634","article-title":"Rate of inpatient weight restoration predicts outcome in anorexia nervosa","volume":"42","author":"Lund","year":"2009","journal-title":"Int J Eat Disord"},{"key":"10.1016\/j.jaac.2021.02.014_bib8","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1016\/j.jand.2018.01.023","article-title":"A\u00a0higher-calorie refeeding protocol does not increase adverse outcomes in adult patients with eating disorders","volume":"118","author":"Matthews","year":"2018","journal-title":"J\u00a0Acad Nutr Diet"},{"key":"10.1016\/j.jaac.2021.02.014_bib9","doi-asserted-by":"crossref","unstructured":"Haas V, Kohn M, K\u00f6rner T, et\u00a0al. Practice-based evidence and clinical guidance to support accelerated re-nutrition of patients with anorexia nervosa [published online ahead of print September 27, 2020]. J Am Acad Child Adolesc Psychiatry. https:\/\/doi.org\/10.1016\/j.jaac.2020.09.010.","DOI":"10.1016\/j.jaac.2020.09.010"},{"key":"10.1016\/j.jaac.2021.02.014_bib10","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1161\/CIRCULATIONAHA.109.192644","volume":"120","author":"Alberti","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.jaac.2021.02.014_bib11","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1002\/eat.23051","article-title":"Increased lipid and lipoprotein concentrations in anorexia nervosa: a systematic review and meta-analysis","volume":"52","author":"Hussain","year":"2019","journal-title":"Int J Eat Disord"},{"key":"10.1016\/j.jaac.2021.02.014_bib12","doi-asserted-by":"crossref","first-page":"3895","DOI":"10.3390\/nu6093895","article-title":"Anorexia nervosa and body fat distribution: a systematic review","volume":"6","author":"El Ghoch","year":"2014","journal-title":"Nutrients"},{"key":"10.1016\/j.jaac.2021.02.014_bib13","doi-asserted-by":"crossref","first-page":"E649","DOI":"10.1002\/oby.20508","article-title":"The effect of short-term overfeeding on serum lipids in healthy humans","volume":"21","author":"Heilbronn","year":"2013","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.jaac.2021.02.014_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000443","article-title":"Machine learning of human plasma lipidomes for obesity estimation in a large population cohort","volume":"17","author":"Gerl","year":"2019","journal-title":"PLoS Biol"},{"key":"10.1016\/j.jaac.2021.02.014_bib15","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/nrendo.2016.169","article-title":"Sphingolipids and phospholipids in insulin resistance and related metabolic disorders","volume":"13","author":"Meikle","year":"2017","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.jaac.2021.02.014_bib16","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1002\/ejlt.201500145","article-title":"An automated shotgun lipidomics platform for high throughput, comprehensive, and quantitative analysis of blood plasma intact lipids","volume":"117","author":"Surma","year":"2015","journal-title":"Eur J Lipid Sci Technol"},{"key":"10.1016\/j.jaac.2021.02.014_bib17","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1172\/JCI44442","article-title":"Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans","volume":"121","author":"Rhee","year":"2011","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jaac.2021.02.014_bib18","doi-asserted-by":"crossref","first-page":"337","DOI":"10.2337\/db08-1228","article-title":"Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance","volume":"58","author":"Haus","year":"2009","journal-title":"Diabetes"},{"key":"10.1016\/j.jaac.2021.02.014_bib19","doi-asserted-by":"crossref","unstructured":"Monteleone P, Monteleone AM, Troisi J, et\u00a0al. Metabolomics signatures of acutely ill and short-term weight recovered women with anorexia nervosa [published online ahead of print November 7, 2019]. Mol Psychiatry. https:\/\/doi.org\/10.1038\/s41380-019-0573-3.","DOI":"10.1038\/s41380-019-0573-3"},{"key":"10.1016\/j.jaac.2021.02.014_bib20","series-title":"Strukturiertes Inventar f\u00fcr anorektische und bulimische Esst\u00f6rungen (SIAB); Fragebogen (SIAB-S) und Interview (SIAB-EX) nach DSM-IV und ICD-10; Handanweisung","author":"Fichter","year":"1999"},{"key":"10.1016\/j.jaac.2021.02.014_bib21","first-page":"365","article-title":"Eine deutschsprachige Version des Eating Disorder Inventory EDI-2 [A German version of the Eating Disorder Inventory EDI-2]","volume":"47","author":"Thiel","year":"1997","journal-title":"Psychother Psychosom Med Psychol"},{"key":"10.1016\/j.jaac.2021.02.014_bib22","series-title":"Beck Depressions-Inventar (BDI-II)","author":"Hautzinger","year":"2009"},{"key":"10.1016\/j.jaac.2021.02.014_bib23","series-title":"Symptom-Checkliste von LR Derogatis: SCL-90-R; Deutsche Version","author":"Franke","year":"2002"},{"key":"10.1016\/j.jaac.2021.02.014_bib24","series-title":"WIE\u2500Wechsler Intelligenztest f\u00fcr Erwachsene","author":"von Aster","year":"2006"},{"key":"10.1016\/j.jaac.2021.02.014_bib25","series-title":"HAWIK IV. Hamburg-Wechsler-Intelligenztest f\u00fcr Kinder IV. \u00dcbersetzung und Adaptation der WISC-IV von David Wechsler","author":"Petermann","year":"2010"},{"key":"10.1016\/j.jaac.2021.02.014_bib26","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1055\/s-0030-1253666","article-title":"[Percentiles of body mass index of 18-80-year-old German adults based on data from the Second National Nutrition Survey]","volume":"135","author":"Hemmelmann","year":"2010","journal-title":"Dtsch Med Wochenschr"},{"key":"10.1016\/j.jaac.2021.02.014_bib27","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s001120170107","article-title":"Perzentile f\u00fcr den Body-mass-Index f\u00fcr das Kindes- und Jugendalter unter Heranziehung verschiedener deutscher Stichproben","volume":"149","author":"Kromeyer-Hauschild","year":"2001","journal-title":"Monatsschr Kinderheilkd"},{"key":"10.1016\/j.jaac.2021.02.014_bib28","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2014a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J\u00a0Biomed Inform"},{"key":"10.1016\/j.jaac.2021.02.014_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0029851","article-title":"LipidXplorer: a software for consensual cross-platform lipidomics","volume":"7","author":"Herzog","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jaac.2021.02.014_bib30","doi-asserted-by":"crossref","first-page":"R8","DOI":"10.1186\/gb-2011-12-1-r8","article-title":"A\u00a0novel informatics concept for high-throughput shotgun lipidomics based on the molecular fragmentation query language","volume":"12","author":"Herzog","year":"2011","journal-title":"Genome Biol"},{"key":"10.1016\/j.jaac.2021.02.014_bib31","doi-asserted-by":"crossref","first-page":"2860","DOI":"10.1093\/bioinformatics\/btv285","article-title":"The SwissLipids knowledgebase for lipid biology","volume":"31","author":"Aimo","year":"2015","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaac.2021.02.014_bib33","author":"Wickham"},{"key":"10.1016\/j.jaac.2021.02.014_bib34","article-title":"Coronary artery disease risk and lipidomic profiles are similar in hyperlipidemias with family history and population-ascertained hyperlipidemias","volume":"8","author":"R\u00e4m\u00f6","year":"2019","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jaac.2021.02.014_bib35","article-title":"Large-scale lipidomics identifies associations between plasma sphingolipids and T2DM incidence","volume":"5","author":"Chew","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.jaac.2021.02.014_bib36","author":"Zou"},{"key":"10.1016\/j.jaac.2021.02.014_bib37","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1093\/ije\/dyx239","article-title":"Cohort profile: the National FINRISK Study","volume":"47","author":"Borodulin","year":"2018","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.jaac.2021.02.014_bib38","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1515\/jpem-2012-0407","article-title":"Plasma ceramides are elevated in female children and adolescents with type 2 diabetes","volume":"26","author":"Lopez","year":"2013","journal-title":"J\u00a0Pediatr Endocrinol Metab"},{"key":"10.1016\/j.jaac.2021.02.014_bib39","doi-asserted-by":"crossref","first-page":"2424","DOI":"10.1161\/ATVBAHA.116.307497","article-title":"Circulating ceramides predict cardiovascular outcomes in the population-based FINRISK 2002 cohort","volume":"36","author":"Havulinna","year":"2016","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jaac.2021.02.014_bib40","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1126\/science.aav3722","article-title":"Targeting a ceramide double bond improves insulin resistance and hepatic steatosis","volume":"365","author":"Chaurasia","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.jaac.2021.02.014_bib41","doi-asserted-by":"crossref","first-page":"4222","DOI":"10.1172\/JCI57144","article-title":"Ceramides as modulators of cellular and whole-body metabolism","volume":"121","author":"Bikman","year":"2011","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jaac.2021.02.014_bib42","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.jpsychires.2018.06.002","article-title":"A\u00a0meta-analysis of cytokine concentrations in eating disorders","volume":"103","author":"Dalton","year":"2018","journal-title":"J\u00a0Psychiatr Res"},{"key":"10.1016\/j.jaac.2021.02.014_bib43","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.cmet.2017.12.003","article-title":"Could ceramides become the new cholesterol?","volume":"27","author":"Summers","year":"2018","journal-title":"Cell Metab"},{"key":"10.1016\/j.jaac.2021.02.014_bib44","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0002630","article-title":"Triacylglycerol fatty acid composition in diet-induced weight loss in subjects with abnormal glucose metabolism\u2500the GENOBIN study","volume":"3","author":"Schwab","year":"2008","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jaac.2021.02.014_bib45","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.tem.2019.02.008","article-title":"Common fatty markers in diseases with dysregulated lipogenesis","volume":"30","author":"Balgoma","year":"2019","journal-title":"Trends Endocrinol Metab"},{"key":"10.1016\/j.jaac.2021.02.014_bib46","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.cmet.2018.09.022","article-title":"Profound perturbation of the metabolome in obesity is associated with health risk","volume":"29","author":"Cirulli","year":"2019","journal-title":"Cell Metab"},{"key":"10.1016\/j.jaac.2021.02.014_bib47","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1002\/eat.22964","article-title":"A\u00a0pilot randomized controlled trial of omega-3 fatty acid supplementation for the treatment of anxiety in adolescents with anorexia nervosa","volume":"51","author":"Manos","year":"2018","journal-title":"Int J Eat Disord"},{"key":"10.1016\/j.jaac.2021.02.014_bib48","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.2337\/db12-0363","article-title":"A\u00a0lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults","volume":"62","author":"Kien","year":"2013","journal-title":"Diabetes"},{"key":"10.1016\/j.jaac.2021.02.014_bib49","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.2337\/dc18-0071","article-title":"Saturated fat is more metabolically harmful for the human liver than unsaturated fat or simple sugars","volume":"41","author":"Luukkonen","year":"2018","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jaac.2021.02.014_bib50","first-page":"662","article-title":"A\u00a0healthy nordic diet\u00a0alters the plasma lipidomic profile in adults with features of metabolic syndrome in a multicenter randomized dietary intervention","volume":"146","author":"Lankinen","year":"2016","journal-title":"J\u00a0Nutr"}],"container-title":["Journal of the American Academy of Child & Adolescent Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890856721001374?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890856721001374?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T14:30:54Z","timestamp":1760193054000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890856721001374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":48,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["S0890856721001374"],"URL":"https:\/\/doi.org\/10.1016\/j.jaac.2021.02.014","relation":{},"ISSN":["0890-8567"],"issn-type":[{"value":"0890-8567","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adverse Effects of Refeeding on the Plasma Lipidome in\u00a0Young Individuals With Anorexia Nervosa?","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Child & Adolescent Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaac.2021.02.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a92021 American Academy of Child and Adolescent Psychiatry","name":"copyright","label":"Copyright"}]}}