{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T23:23:49Z","timestamp":1783466629515,"version":"3.55.0"},"reference-count":15,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1016\/j.jaad.2005.07.021","type":"journal-article","created":{"date-parts":[[2005,10,24]],"date-time":"2005-10-24T14:12:38Z","timestamp":1130163158000},"page":"881-884","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["Symptomatic treatment of idiopathic and rosacea-associated cutaneous flushing with propranolol"],"prefix":"10.1016","volume":"53","author":[{"given":"Helen","family":"Craige","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack B.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaad.2005.07.021_bib1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1159\/000247849","article-title":"Idiopathic recalcitrant facial flushing syndrome","volume":"181","author":"Tur","year":"1990","journal-title":"Dermatologica"},{"key":"10.1016\/j.jaad.2005.07.021_bib2","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0091-6749(94)90232-1","article-title":"A clinicopathologic study of ten patients with recurrent unexplained flushing","volume":"93","author":"Friedman","year":"1994","journal-title":"J Allergy Clin Immnunol"},{"key":"10.1016\/j.jaad.2005.07.021_bib3","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/S0190-9622(89)70022-0","article-title":"Effect of nadolol on flushing reactions in rosacea","volume":"20","author":"Wilkin","year":"1989","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2005.07.021_bib4","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1469-8986.1997.tb02127.x","article-title":"The effect of adrenergic blockade on blushing and facial flushing","volume":"34","author":"Drummond","year":"1997","journal-title":"Psychophysiology"},{"key":"10.1016\/j.jaad.2005.07.021_bib5","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1001\/archderm.1983.01650270029012","article-title":"Effect of subdepressor clonidine on flushing of reactions in rosacea","volume":"119","author":"Wilkin","year":"1983","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2005.07.021_bib6","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1097\/00019509-200010000-00011","article-title":"Thoracoscopic sympathectomy","volume":"10","author":"Krasna","year":"2000","journal-title":"Surg Laprosc Endosc Percutan Tech"},{"key":"10.1016\/j.jaad.2005.07.021_bib7","first-page":"102","article-title":"Botulinum toxin for the treatment of facial flushing","volume":"30","author":"Yuraitis","year":"2004","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.jaad.2005.07.021_bib8","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1046\/j.1365-2230.2003.01379.x","article-title":"Successful use of botulinum toxin-A for the treatment of neck and anterior chest wall flushing","volume":"28","author":"Sterodimas","year":"2003","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.jaad.2005.07.021_bib9","first-page":"74","article-title":"Biofeedback training in the therapy of flushing","volume":"31","author":"Wilkin","year":"1983","journal-title":"Cutis"},{"key":"10.1016\/j.jaad.2005.07.021_bib10","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/00004714-199004000-00010","article-title":"Treatment of panic-like attacks with long-acting analogue of somatostatin","volume":"10","author":"Abelson","year":"1990","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/j.jaad.2005.07.021_bib11","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1056\/NEJM198202183060705","article-title":"The drug treatment of anxiety","volume":"306","author":"Rosenbaum","year":"1982","journal-title":"N Engl J Med"},{"issue":"Suppl 2","key":"10.1016\/j.jaad.2005.07.021_bib12","first-page":"16","article-title":"Beta blockade in anxiety","volume":"60","author":"Peat","year":"1984","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.jaad.2005.07.021_bib13","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/BF01541742","article-title":"Beta-blocker effects on sexual function in normal males","volume":"17","author":"Rosen","year":"1988","journal-title":"Arch Sex Behav"},{"key":"10.1016\/j.jaad.2005.07.021_bib14","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1136\/thx.38.2.108","article-title":"Beta-blockade in bronchial asthma; effect of propranolol and pindolol on large and small airways","volume":"38","author":"Patakas","year":"1983","journal-title":"Thorax"},{"key":"10.1016\/j.jaad.2005.07.021_bib15","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/S0190-9622(86)70265-X","article-title":"Drugs in exacerbation of psoriasis","volume":"15","author":"Abel","year":"1986","journal-title":"J Am Acad Dermatol"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962205022966?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962205022966?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T21:39:43Z","timestamp":1759268383000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962205022966"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S0190962205022966"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2005.07.021","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Symptomatic treatment of idiopathic and rosacea-associated cutaneous flushing with propranolol","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2005.07.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}