{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T20:56:46Z","timestamp":1783976206002,"version":"3.55.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2006,3]]},"DOI":"10.1016\/j.jaad.2005.10.017","type":"journal-article","created":{"date-parts":[[2006,2,20]],"date-time":"2006-02-20T10:57:23Z","timestamp":1140433043000},"page":"499-504","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":82,"title":["Angiosarcoma after conservation treatment for breast carcinoma: Our experience and a review of the literature"],"prefix":"10.1016","volume":"54","author":[{"given":"J\u00e1nos","family":"Fodor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsolt","family":"Orosz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c9va","family":"Szab\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"Sulyok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Csaba","family":"Polg\u00e1r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"Zaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tibor","family":"Major","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaad.2005.10.017_bib1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1023\/A:1005997017102","article-title":"Angiosarcoma of the breast after conservation therapy for invasive cancer, the incidence and outcome. An unforeseen sequela","volume":"47","author":"Strobbe","year":"1998","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.jaad.2005.10.017_bib2","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1002\/1097-0142(20010701)92:1<172::AID-CNCR1306>3.0.CO;2-K","article-title":"Increased risk of soft tissue sarcoma after radiotherapy in women with breast carcinoma","volume":"92","author":"Huang","year":"2001","journal-title":"Cancer"},{"key":"10.1016\/j.jaad.2005.10.017_bib3","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0360-3016(01)02799-7","article-title":"Sarcoma as a second malignancy after treatment for breast cancer","volume":"52","author":"Yap","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jaad.2005.10.017_bib4","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1002\/cncr.11277","article-title":"Angiosarcoma after breast-conserving therapy","volume":"97","author":"Monroe","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.jaad.2005.10.017_bib5","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/1097-0142(194805)1:1<64::AID-CNCR2820010105>3.0.CO;2-W","article-title":"Lymphangiosarcoma in postmastectomy lymphedema. A report of six cases in elephantiasis chirurgica","volume":"1","author":"Stewart","year":"1948","journal-title":"Cancer"},{"key":"10.1016\/j.jaad.2005.10.017_bib6","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1093\/oxfordjournals.annonc.a058770","article-title":"Angiosarcoma of the residual breast after conservative surgery and radiotherapy for primary carcinoma","volume":"5","author":"Del Mastro","year":"1994","journal-title":"Ann Oncol"},{"key":"10.1016\/j.jaad.2005.10.017_bib7","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0360-3016(98)00537-9","article-title":"Nine breast angiosarcomas after conservative treatment for breast carcinoma: a survey from French Comprehensive Cancer Centers","volume":"44","author":"Marchal","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jaad.2005.10.017_bib8","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1002\/1096-9098(200007)74:3<208::AID-JSO10>3.0.CO;2-2","article-title":"Cutaneous angiosarcoma in an irradiated breast after breast conservation therapy for cancer: association with chronic breast lymphedema","volume":"74","author":"Majeski","year":"2000","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.jaad.2005.10.017_bib9","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1053\/ejso.2000.1073","article-title":"Angiosarcoma after conservative treatment and radiation therapy for adenocarcinoma of the breast","volume":"27","author":"Lamblin","year":"2001","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.jaad.2005.10.017_bib10","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/S1072-7515(01)00863-8","article-title":"The spectrum of vascular lesions in the mammary skin, including angiosarcoma, after breast conservation treatment for breast cancer","volume":"193","author":"Sener","year":"2001","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.jaad.2005.10.017_bib11","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0360-3016(01)02669-4","article-title":"Angiosarcoma after breast-conserving therapy: experience with hyperfractionated radiotherapy","volume":"52","author":"Feigenberg","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jaad.2005.10.017_bib12","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1002\/1097-0142(19820601)49:11<2295::AID-CNCR2820491116>3.0.CO;2-G","article-title":"Breast edema following staging axillary node dissection in patients with breast carcinoma treated by radical radiotherapy","volume":"49","author":"Clarke","year":"1982","journal-title":"Cancer"},{"key":"10.1016\/j.jaad.2005.10.017_bib13","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/1097-0142(194805)1:1<3::AID-CNCR2820010103>3.0.CO;2-7","article-title":"Sarcoma arising in irradiated bone: report of eleven cases","volume":"1","author":"Cahan","year":"1948","journal-title":"Cancer"},{"key":"10.1016\/j.jaad.2005.10.017_bib14","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/0360-3016(91)90783-Z","article-title":"Long-term risk of sarcoma following radiation treatment for breast cancer","volume":"21","author":"Taghian","year":"1991","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jaad.2005.10.017_bib15","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1016\/0959-8049(96)00180-3","article-title":"Angiosarcoma of the breast after conservative surgery and radiation therapy for breast carcinoma: three new cases","volume":"32A","author":"Molitor","year":"1996","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.jaad.2005.10.017_bib16","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1148\/radiology.216.1.r00jl02197","article-title":"Sarcoma after radiation therapy: retrospective multiinstitutional study of 80 histologically confirmed cases","volume":"216","author":"Lagrange","year":"2000","journal-title":"Radiology"},{"key":"10.1016\/j.jaad.2005.10.017_bib17","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1097\/01.pas.0000126055.33916.0b","article-title":"Cutaneous angiosarcoma following breast-conserving surgery and radiation: an analysis of 27 cases","volume":"28","author":"Billings","year":"2004","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.jaad.2005.10.017_bib18","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1093\/ajcp\/87.5.651","article-title":"Angiosarcoma of the breast following segmental mastectomy complicated by lymphedema","volume":"87","author":"Benda","year":"1987","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.jaad.2005.10.017_bib19","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/0360-3016(95)00060-C","article-title":"Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC)","volume":"31","author":"Cox","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jaad.2005.10.017_bib20","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0360-3016(93)90184-W","article-title":"Angiosarcoma of the breast following lumpectomy, axillary lymph node dissection, and radiotherapy for primary breast cancer: three case reports and review of the literature","volume":"26","author":"Wijnmaalen","year":"1993","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jaad.2005.10.017_bib21","doi-asserted-by":"crossref","first-page":"2965","DOI":"10.1002\/1097-0142(19920615)69:12<2965::AID-CNCR2820691216>3.0.CO;2-H","article-title":"Angiosarcoma of the breast after lumpectomy and radiation therapy for adenocarcinoma","volume":"69","author":"Stokkel","year":"1992","journal-title":"Cancer"},{"key":"10.1016\/j.jaad.2005.10.017_bib22","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1067\/S0190-9622(03)00428-6","article-title":"Cutaneous angiosarcoma as a delayed complication of radiation therapy for carcinoma of the breast","volume":"49","author":"Rao","year":"2003","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2005.10.017_bib23","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/S0190-9622(96)90444-2","article-title":"Angiogenesis and the skin: a primer","volume":"34","author":"Arbiser","year":"1996","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2005.10.017_bib24","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1067\/mjd.2000.111632","article-title":"Differential expression of active mitogen-activated protein kinase in cutaneous endothelial neoplasms: implications for biologic behavior and response to therapy","volume":"44","author":"Arbiser","year":"2001","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2005.10.017_bib25","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1016\/S0002-9440(10)65729-X","article-title":"MDM-2 oncoprotein overexpression, p53 gene mutation, and VEGF up-regulation in angiosarcomas","volume":"153","author":"Zietz","year":"1998","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jaad.2005.10.017_bib26","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1046\/j.1523-1747.2000.00005-3.x","article-title":"VEGF and its receptors are expressed in a pediatric angiosarcoma in a patient with Aicardi's syndrome","volume":"114","author":"McLaughlin","year":"2000","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaad.2005.10.017_bib27","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/S0190-9622(99)70080-0","article-title":"The antiangiogenic agents TNP-470 and 2-methoxyestradiol inhibit the growth of angiosarcoma in mice","volume":"40","author":"Arbiser","year":"1999","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2005.10.017_bib28","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1016\/S0002-9440(10)64832-8","article-title":"Inhibition of MAP kinase kinase causes morphological reversion and dissociation between soft agar growth and in vivo tumorigenesis in angiosarcoma cells","volume":"157","author":"LaMontagne","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jaad.2005.10.017_bib29","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1016\/S0002-9440(10)65015-8","article-title":"Overexpression of VEGF 121 in immortalized endothelial cells causes conversion to slowly growing angiosarcoma and high level expression of the VEGF receptors VEGFR-1 and VEGFR-2 in vivo","volume":"156","author":"Arbiser","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jaad.2005.10.017_bib30","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S0002-9440(10)64237-X","article-title":"Functional tyrosine kinase inhibitor profiling: a generally applicable method points to a novel role of platelet-derived growth factor receptor-beta in tuberous sclerosis","volume":"161","author":"Arbiser","year":"2002","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jaad.2005.10.017_bib31","first-page":"2926","article-title":"Clinicopathologic assessment of postirradiation sarcomas: KIT as a potential treatment target","volume":"9","author":"Komdeur","year":"2003","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.jaad.2005.10.017_bib32","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0167-8140(95)01663-5","article-title":"Soft tissue sarcoma after treatment for breast cancer","volume":"38","author":"Karlsson","year":"1996","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.jaad.2005.10.017_bib33","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1002\/bjs.1800730723","article-title":"Risk of lymphoedema following the treatment of breast cancer","volume":"73","author":"Kissin","year":"1986","journal-title":"Br J Surg"},{"key":"10.1016\/j.jaad.2005.10.017_bib34","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1086\/314021","article-title":"Risk factor analysis for breast cellulitis complicating breast conservation therapy","volume":"31","author":"Brewer","year":"2000","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jaad.2005.10.017_bib35","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1056\/NEJMcp031807","article-title":"Clinical practice","volume":"350","author":"Swartz","year":"2004","journal-title":"Cellulitis. N Engl J Med"},{"key":"10.1016\/j.jaad.2005.10.017_bib36","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0360-3016(94)90239-9","article-title":"Breast cellulitis after conservative surgery and radiotherapy","volume":"29","author":"Rescigno","year":"1994","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jaad.2005.10.017_bib37","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0360-3016(95)90369-0","article-title":"In response to Rescigno et al (Int J Radiat Oncol Biol Phys 1995;29:163-8)","volume":"31","author":"Olivotto","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jaad.2005.10.017_bib38","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1097\/00000421-199708000-00003","article-title":"Cellulitis of the breast as a complication of breast-conserving surgery and irradiation","volume":"20","author":"Hughes","year":"1997","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.jaad.2005.10.017_bib39","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1067\/mjd.2002.120909","article-title":"Lymphedema: an immunologically vulnerable site for development of neoplasms","volume":"47","author":"Ruocco","year":"2002","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2005.10.017_bib40","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1089\/153968503322758076","article-title":"Molecular pathogenesis of vascular anomalies: classification into three categories based upon clinical and biochemical characteristics","volume":"1","author":"Chiller","year":"2003","journal-title":"Lymphat Res Biol"},{"key":"10.1016\/j.jaad.2005.10.017_bib41","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.humpath.2004.02.009","article-title":"Expression of a lymphatic endothelial cell marker in benign and malignant vascular tumors","volume":"35","author":"Xu","year":"2004","journal-title":"Hum Pathol"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962205032494?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962205032494?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:02:25Z","timestamp":1759269745000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962205032494"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3]]},"references-count":41,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["S0190962205032494"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2005.10.017","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2006,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Angiosarcoma after conservation treatment for breast carcinoma: Our experience and a review of the literature","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2005.10.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}