{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:06:15Z","timestamp":1759334775617,"version":"build-2065373602"},"reference-count":13,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2010,1]]},"DOI":"10.1016\/j.jaad.2009.01.032","type":"journal-article","created":{"date-parts":[[2009,9,7]],"date-time":"2009-09-07T04:28:24Z","timestamp":1252297704000},"page":"142-144","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Re-emergence of anti-topoisomerase I antibody with exacerbated development of skin sclerosis in a patient with systemic sclerosis"],"prefix":"10.1016","volume":"62","author":[{"given":"Yasuhito","family":"Hamaguchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manabu","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minoru","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Matsushita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiko","family":"Takehara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaad.2009.01.032_bib1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0065-2776(08)60641-0","article-title":"Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology","volume":"44","author":"Tan","year":"1989","journal-title":"Adv Immunol"},{"key":"10.1016\/j.jaad.2009.01.032_bib2","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/art.1780370111","article-title":"Clinical and prognostic associations based on serum antinuclear antibodies in Japanese patients with systemic sclerosis","volume":"37","author":"Kuwana","year":"1994","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jaad.2009.01.032_bib3","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1111\/j.1365-2133.2007.08392.x","article-title":"The clinical relevance of serum antinuclear antibodies in Japanese patients with systemic sclerosis","volume":"158","author":"Hamaguchi","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2009.01.032_bib4","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1126\/science.3003910","article-title":"High titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patients","volume":"231","author":"Shero","year":"1986","journal-title":"Science"},{"key":"10.1016\/j.jaad.2009.01.032_bib5","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.semarthrit.2005.03.005","article-title":"Autoantibodies in systemic sclerosis","volume":"35","author":"Steen","year":"2005","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.jaad.2009.01.032_bib6","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1002\/1529-0131(199809)41:9<1613::AID-ART11>3.0.CO;2-O","article-title":"Case-control study of corticosteroids and other drugs that either precipitate or protect from the development of scleroderma renal crisis","volume":"41","author":"Steen","year":"1998","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jaad.2009.01.032_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0889-857X(21)00892-9","article-title":"Epidemiology and natural history of systemic sclerosis","volume":"16","author":"Steen","year":"1990","journal-title":"Rheum Dis Clin North Am"},{"key":"10.1016\/j.jaad.2009.01.032_bib8","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1002\/art.11113","article-title":"Evidence-based guidelines for the use of immunologic tests: anticentromere, Scl-70, and nucleolar antibodies","volume":"49","author":"Reveille","year":"2003","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jaad.2009.01.032_bib9","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1006\/clin.1995.1038","article-title":"Longitudinal study of anticentromere and antitopoisomerase-I isotypes","volume":"74","author":"V\u00e1zquez-Abad","year":"1995","journal-title":"Clin Immunol Immunopathol"},{"key":"10.1016\/j.jaad.2009.01.032_bib10","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1002\/art.10977","article-title":"Correlation of serum anti-DNA topoisomerase I antibody levels with disease severity and activity in systemic sclerosis","volume":"48","author":"Hu","year":"2003","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jaad.2009.01.032_bib11","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1093\/rheumatology\/40.10.1135","article-title":"Clinical significance of anti-topoisomerase I antibody levels determined by ELISA in systemic sclerosis","volume":"40","author":"Sato","year":"2001","journal-title":"Rheumatology"},{"key":"10.1016\/j.jaad.2009.01.032_bib12","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1002\/1529-0131(200005)43:5<1074::AID-ANR18>3.0.CO;2-E","article-title":"Longitudinal analysis of autoantibody response to topoisomerase I in systemic sclerosis","volume":"43","author":"Kuwana","year":"2000","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jaad.2009.01.032_bib13","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1002\/art.21646","article-title":"DNA topoisomerase I binding to fibroblasts induces monocyte adhesion and activation in the presence of anti-topoisomerase I autoantibodies from systemic sclerosis patients","volume":"54","author":"H\u00e9nault","year":"2006","journal-title":"Arthritis Rheum"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962209001297?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962209001297?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:15:17Z","timestamp":1759270517000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962209001297"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["S0190962209001297"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2009.01.032","relation":{},"ISSN":["0190-9622"],"issn-type":[{"type":"print","value":"0190-9622"}],"subject":[],"published":{"date-parts":[[2010,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Re-emergence of anti-topoisomerase I antibody with exacerbated development of skin sclerosis in a patient with systemic sclerosis","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2009.01.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}