{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T04:37:24Z","timestamp":1783485444591,"version":"3.55.0"},"reference-count":19,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1016\/j.jaad.2009.02.037","type":"journal-article","created":{"date-parts":[[2009,8,27]],"date-time":"2009-08-27T02:28:32Z","timestamp":1251340112000},"page":"592.e1-592.e9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Phase I\/II randomized bilateral half-head comparison of topical bexarotene 1% gel for alopecia areata"],"prefix":"10.1016","volume":"61","author":[{"given":"Rakhshandra","family":"Talpur","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Vu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"Bassett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeleine","family":"Duvic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaad.2009.02.037_bib1","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1067\/mjd.2001.114581","article-title":"Evidence based treatment of alopecia areata","volume":"45","author":"Epstein","year":"2001","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2009.02.037_bib2","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.jaad.2003.09.032","article-title":"Alopecia areata investigational assessment guidelines\u2013part II","volume":"51","author":"Olsen","year":"2004","journal-title":"J Am Acad Dermal"},{"key":"10.1016\/j.jaad.2009.02.037_bib3","doi-asserted-by":"crossref","first-page":"29","DOI":"10.4103\/0378-6323.30648","article-title":"Combination of topical garlic gel and betamethasone valerate cream in treatment of localized alopecia areata: a double blind randomized controlled study","volume":"73","author":"Hajheydari","year":"2007","journal-title":"Indian J Dermatol Venereol Leperol"},{"key":"10.1016\/j.jaad.2009.02.037_bib4","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/S0190-9622(98)70499-2","article-title":"Alopecia areata and cytomegalovirus infections in twins: genes vs environment","volume":"38","author":"Jackow","year":"1998","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2009.02.037_bib5","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1001\/archderm.138.7.916","article-title":"Mediation of alopecia areata by cooperation between CD4+ and CD8+ T lymphocytes: transfer to human scalp explants on Prkdc (scid) mice","volume":"138","author":"Gilhar","year":"2002","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2009.02.037_bib6","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1046\/j.1365-2133.1999.02705.x","article-title":"Partial restoration of hair growth in the DEBR model for alopecia areata after in vivo depletion of CD4+ T-cells","volume":"140","author":"McElwee","year":"1999","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2009.02.037_bib7","first-page":"581","article-title":"Phase 2-3 clinical trial of oral Targretin (bexarotene) capsules for the treatment of refractory or persistent early stage cutaneous T-cell lymphoma","volume":"137","author":"Duvic","year":"2001","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2009.02.037_bib8","first-page":"1234","article-title":"Induction of apoptosis by bexarotene in cutaneous T-cell lymphoma (CTCL) cells: relevance to mechanism to therapeutic action","volume":"8","author":"Zhang","year":"2002","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.jaad.2009.02.037_bib9","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1046\/j.1365-2133.2003.05399.x","article-title":"Bexarotene reverses alopecia in cutaneous T-cell lymphoma","volume":"149","author":"Hanson","year":"2003","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2009.02.037_bib10","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1200\/JCO.1996.14.1.296","article-title":"New statistical strategy for monitoring safety and efficacy in single arm clinical trials","volume":"14","author":"Thall","year":"1996","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jaad.2009.02.037_bib11","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1111\/1523-1747.ep12412584","article-title":"Human leukocyte antigen-DQ01\u221703 alleles are associated with alopecia areata","volume":"103","author":"Welsh","year":"1994","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaad.2009.02.037_bib12","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1111\/1523-1747.ep12363352","article-title":"HLA-DR5 and DQB1\u221703 class II alleles are associated with cutaneous T cell lymphoma","volume":"107","author":"Jackow","year":"1996","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaad.2009.02.037_bib13","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1365-4362.1996.tb03281.x","article-title":"Pulsed administration of corticosteroids in the treatment of alopecia areata","volume":"35","author":"Sharma","year":"1996","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.jaad.2009.02.037_bib14","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1001\/archderm.1992.01680210045005","article-title":"Systemic steroids with or without 2% topical minoxidil in the treatment of alopecia areata","volume":"128","author":"Olsen","year":"1992","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2009.02.037_bib15","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1172\/JCI31942","article-title":"Lymphocytes, neuropeptides, and genes involved in alopecia areata","volume":"117","author":"Gilhar","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaad.2009.02.037_bib16","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1001\/archderm.139.12.1555","article-title":"Histopathologic features of alopecia areata: a new look","volume":"139","author":"Whiting","year":"2003","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2009.02.037_bib17","first-page":"1","article-title":"Successful treatment of alopecia areata with efalizumab","author":"Kolde","year":"2008","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.jaad.2009.02.037_bib18","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.jaad.2007.10.645","article-title":"Subcutaneous efalizumab in the treatment of alopecia areata","author":"Price","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2009.02.037_bib19","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0190-9622(94)70066-4","article-title":"Response of psoriasis to a new topical retinoid, AGN 190168","volume":"30","author":"Esgleyes-Ribot","year":"1994","journal-title":"J Am Acad Dermatol"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962209002473?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962209002473?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:15:32Z","timestamp":1759270532000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962209002473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["S0190962209002473"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2009.02.037","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1165671.628696","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.1165671.3011054","asserted-by":"object"}]},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phase I\/II randomized bilateral half-head comparison of topical bexarotene 1% gel for alopecia areata","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2009.02.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}