{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T12:44:40Z","timestamp":1760100280494,"version":"build-2065373602"},"reference-count":46,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.1016\/j.jaad.2009.10.011","type":"journal-article","created":{"date-parts":[[2010,7,3]],"date-time":"2010-07-03T04:34:40Z","timestamp":1278131680000},"page":"430-439","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effect of hair color and sun sensitivity on nevus counts in white children in Colorado"],"prefix":"10.1016","volume":"63","author":[{"given":"Jenny","family":"Aalborg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph G.","family":"Morelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim E.","family":"Byers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan T.","family":"Mokrohisky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lori A.","family":"Crane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaad.2009.10.011_bib1","unstructured":"American Cancer Society. Detailed guide: skin cancer\u2013melanoma. Available from: URL:http:\/\/www.cancer.org\/docroot\/CRI\/content\/CRI_2_4_1X_What_are_the_key_statistics_for_melanoma_50.asp?sitearea=. Accessed April 1, 2009."},{"key":"10.1016\/j.jaad.2009.10.011_bib2","first-page":"71","article-title":"Cancer statistics, 2008","volume":"58","author":"Jemal","year":"2008","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.jaad.2009.10.011_bib3","unstructured":"Ries LAG, Melbert D, Krapcho M, Stinchcomb DG, Howlader N, Horner MJ, et al, editors. Surveillance Epidemiology and End Results (SEER), Cancer Stat Fact Sheets, Melanoma of the Skin. National Cancer Institute. Bethesda, MD. Available from: URL:http:\/\/seer.cancer.gov\/csr\/1975_2005\/, based on November 2007 SEER data submission, posted to the SEER web site, 2008. Accessed August 1, 2009"},{"key":"10.1016\/j.jaad.2009.10.011_bib4","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1002\/ijc.2910420210","article-title":"The Danish case-control study of cutaneous malignant melanoma, I: importance of host factors","volume":"42","author":"Osterlind","year":"1988","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jaad.2009.10.011_bib5","first-page":"257","article-title":"Pigmentary traits, ethnic origin, benign nevi, and family history as risk factors for cutaneous malignant melanoma","volume":"72","author":"Holman","year":"1984","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.jaad.2009.10.011_bib6","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1034\/j.1600-0749.2003.00047.x","article-title":"Acquired melanocytic nevi as risk factor for melanoma development: a comprehensive review of epidemiological data","volume":"16","author":"Bauer","year":"2003","journal-title":"Pigment Cell Res"},{"key":"10.1016\/j.jaad.2009.10.011_bib7","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/0190-9622(95)90294-5","article-title":"Benign melanocytic lesions: risk markers or precursors of cutaneous melanoma?","volume":"33","author":"Skender-Kalnenas","year":"1995","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib8","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1056\/NEJM193904202201601","article-title":"Malignant melanomas: a clinical study","volume":"230","author":"Daland","year":"1939","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaad.2009.10.011_bib9","first-page":"233","article-title":"Melanoma of skin: clinical account of a series of 209 malignant neoplasms of the skin","volume":"13","author":"Cameron","year":"1968","journal-title":"J R Coll Surg Edinb"},{"key":"10.1016\/j.jaad.2009.10.011_bib10","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/ijc.2910620402","article-title":"Risk of cutaneous melanoma associated with pigmentation characteristics and freckling: systematic overview of 10 case-control studies; the international melanoma analysis group (IMAGE)","volume":"62","author":"Bliss","year":"1995","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jaad.2009.10.011_bib11","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.2741\/1877","article-title":"The current epidemiology of cutaneous malignant melanoma","volume":"11","author":"Berwick","year":"2006","journal-title":"Front Biosci"},{"key":"10.1016\/j.jaad.2009.10.011_bib12","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1001\/archderm.1992.01680190057006","article-title":"Benign pigmented nevi in children: prevalence and associated factors; the West Midlands, United Kingdom mole study","volume":"128","author":"Pope","year":"1992","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib13","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1001\/archderm.1990.01670300070010","article-title":"Suntan, sunburn, and pigmentation factors and the frequency of acquired melanocytic nevi in children: similarities to melanoma; the Vancouver mole study","volume":"126","author":"Gallagher","year":"1990","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib14","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1001\/archderm.1990.01670280050008","article-title":"Anatomic distribution of acquired melanocytic nevi in white children: a comparison with melanoma; the Vancouver mole study","volume":"126","author":"Gallagher","year":"1990","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib15","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/S0895-4356(02)00484-5","article-title":"Sun exposure and number of nevi in 5- to\u00a06-year-old European children","volume":"55","author":"Dulon","year":"2002","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.jaad.2009.10.011_bib16","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1080\/00015550410025903","article-title":"Frequency and distribution pattern of melanocytic nevi on Swedish 8-9 year-old children","volume":"84","author":"Synnerstad","year":"2004","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jaad.2009.10.011_bib17","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1097\/CMR.0b013e3282f20192","article-title":"Appearance of melanocytic nevi on the backs of young Australian children: a 7-year longitudinal study","volume":"18","author":"Milne","year":"2008","journal-title":"Melanoma Res"},{"key":"10.1016\/j.jaad.2009.10.011_bib18","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/aje\/kwn289","article-title":"Study of nevi in children (SONIC): baseline findings and predictors of nevus count","volume":"169","author":"Oliveria","year":"2009","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jaad.2009.10.011_bib19","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1158\/1055-9965.EPI-07-0453","article-title":"Melanocytic nevi and sun exposure in a cohort of Colorado children: anatomic distribution and site-specific sunburn","volume":"16","author":"Dodd","year":"2007","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.jaad.2009.10.011_bib20","first-page":"453","article-title":"Number and size of nevi are influenced by different sun exposure components: implications for the etiology of cutaneous melanoma (Belgium, Germany, France, Italy)","volume":"14","author":"Autier","year":"2003","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.jaad.2009.10.011_bib21","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1067\/mjd.2002.120931","article-title":"Longitudinal study of melanocytic nevi on adolescents","volume":"46","author":"Darlington","year":"2002","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib22","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1001\/archdermatol.2008.571","article-title":"Melanocytic nevus development in Colorado children born in 1998: a longitudinal study","volume":"145","author":"Crane","year":"2009","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib23","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1158\/1055-9965.EPI-06-0273","article-title":"The simultaneous assessment of constitutional, behavioral, and environmental factors in the development of large nevi","volume":"16","author":"Cockburn","year":"2007","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.jaad.2009.10.011_bib24","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0190-9622(89)70131-6","article-title":"Melanocytic nevi in schoolchildren in Queensland","volume":"20","author":"Green","year":"1989","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib25","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1001\/archderm.1996.03890360063011","article-title":"Increase of melanocytic nevus counts in children during 5 years of follow-up and analysis of associated factors","volume":"132","author":"Luther","year":"1996","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib26","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1001\/archdermatol.2009.193","article-title":"Tanning increases nevus development in light-skinned children without red hair","volume":"145","author":"Aalborg","year":"2009","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib27","first-page":"1042","article-title":"Children with red hair have more freckles but fewer melanocytic nevi: results from a cohort study of 280 three-year-olds","volume":"141","author":"Dellavalle","year":"2005","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib28","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/hmg\/ddh043","article-title":"Interactive effects of MC1R and OCA2 on melanoma risk phenotypes","volume":"13","author":"Duffy","year":"2004","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jaad.2009.10.011_bib29","unstructured":"Surveillance, Epidemiology, and End Results (SEER) Program, National Cancer Institute (NCI) 1975-1991\u00a0= SEER 9; 1992\u20132005\u00a0= SEER 13. Available from: URL:http:\/\/www.cdc.gov\/cancer\/skin\/statistics\/race.htm. Accessed May 11, 2009."},{"key":"10.1016\/j.jaad.2009.10.011_bib30","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jaad.2004.07.053","article-title":"Melanocytic nevi in very young children: the role of phenotype, sun exposure, and sun protection","volume":"52","author":"Whiteman","year":"2005","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib31","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.2105\/AJPH.86.12.1802","article-title":"Assessing children's ultraviolet radiation exposure: the potential usefulness of a colorimeter","volume":"86","author":"Eckhardt","year":"1996","journal-title":"Am J Public Health"},{"key":"10.1016\/j.jaad.2009.10.011_bib32","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1034\/j.1600-0846.2000.006004230.x","article-title":"Skin color measurements: comparison between three instruments; the Chromameter\u00ae, the DermaSpectrometer\u00ae and the Mexameter\u00ae","volume":"6","author":"Clarys","year":"2000","journal-title":"Skin Res Technol"},{"key":"10.1016\/j.jaad.2009.10.011_bib33","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1001\/archderm.1988.01670060015008","article-title":"The validity and practicality of sun-reactive skin types I through VI","volume":"124","author":"Fitzpatrick","year":"1988","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib34","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1158\/1055-9965.EPI-08-0634","article-title":"Vacations to waterside locations result in nevus development in Colorado children","volume":"18","author":"Pettijohn","year":"2009","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"year":"1991","series-title":"Multiple regressions: testing and interpreting interactions","author":"Aiken","key":"10.1016\/j.jaad.2009.10.011_bib35"},{"key":"10.1016\/j.jaad.2009.10.011_bib36","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1097\/00008390-199506000-00003","article-title":"The incidence of melanocytic nevi in adolescent children in Queensland","volume":"5","author":"Green","year":"1995","journal-title":"Australia. Melanoma Res"},{"key":"10.1016\/j.jaad.2009.10.011_bib37","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/j.1365-2133.1994.tb13106.x","article-title":"Nevi in schoolchildren in Scotland and Australia","volume":"130","author":"Fritschi","year":"1994","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib38","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1002\/ijc.10629","article-title":"The oncology cooperative group of the Italian group for epidemiological research in dermatology: the density of melanocytic nevi correlates with constitutional variables and history of sunburns; a prevalence study among Italian schoolchildren","volume":"101","author":"Carli","year":"2002","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jaad.2009.10.011_bib39","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/ijc.20812","article-title":"Risk factors of incident melanocytic nevi: a longitudinal study in a cohort\u00a0of 1,232 young German children","volume":"115","author":"Bauer","year":"2005","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jaad.2009.10.011_bib40","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1086\/302494","article-title":"A major quantitative-trait locus for mole density is linked to the familial melanoma gene CDKN2A: a maximum-likelihood combined linkage and association analysis in twins and their sibs","volume":"65","author":"Zhu","year":"1999","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jaad.2009.10.011_bib41","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.0022-202X.2004.23548.x","article-title":"The effect of sun exposure in determining nevus density in UK adolescent twins","volume":"124","author":"Wachsmuth","year":"2005","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib42","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1093\/jnci\/95.11.806","article-title":"Melanocytic nevi, solar keratoses, and divergent pathways to cutaneous melanoma","volume":"95","author":"Whiteman","year":"2003","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.jaad.2009.10.011_bib43","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1093\/jnci\/81.12.948","article-title":"Moles and site-specific risk of nonfamilial cutaneous malignant melanoma in women","volume":"81","author":"Weinstock","year":"1989","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.jaad.2009.10.011_bib44","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1038\/jid.2009.182","article-title":"The association between MC1R genotype and BRAF mutation status in cutaneous melanoma: findings from an Australian population","volume":"130","author":"Hacker","year":"2010","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaad.2009.10.011_bib45","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1002\/ijc.24011","article-title":"Nevus density and melanoma risk in women: a pooled analysis to test the divergent pathway hypothesis","volume":"124","author":"Olsen","year":"2009","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jaad.2009.10.011_bib46","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1002\/ijc.24327","article-title":"Genetic variants in pigmentation genes, pigmentary phenotypes, and risk\u00a0of\u00a0skin cancer in Caucasians","volume":"125","author":"Nan","year":"2009","journal-title":"Int J Cancer"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962209012572?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962209012572?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:17:55Z","timestamp":1759270675000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962209012572"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["S0190962209012572"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2009.10.011","relation":{},"ISSN":["0190-9622"],"issn-type":[{"type":"print","value":"0190-9622"}],"subject":[],"published":{"date-parts":[[2010,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of hair color and sun sensitivity on nevus counts in white children in Colorado","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2009.10.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}