{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T16:00:41Z","timestamp":1792684841146,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.jaad.2011.11.937","type":"journal-article","created":{"date-parts":[[2012,3,4]],"date-time":"2012-03-04T00:23:50Z","timestamp":1330820630000},"page":"582-586","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":65,"title":["The natural history of halo nevi: A retrospective case series"],"prefix":"10.1016","volume":"67","author":[{"given":"Mouhammad","family":"Aouthmany","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mara","family":"Weinstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Zirwas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert T.","family":"Brodell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaad.2011.11.937_bib1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1001\/archderm.1965.01600130020003","article-title":"Broad spectrum of leukoderma acquisitum centrifugum","volume":"92","author":"Kopf","year":"1965","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2011.11.937_bib2","first-page":"139","article-title":"Halo phenomenon with regression of acquired melanocytic nevi: a case report","volume":"17","author":"Rados","year":"2009","journal-title":"Acta Dermatovenerol Croat"},{"key":"10.1016\/j.jaad.2011.11.937_bib3","doi-asserted-by":"crossref","first-page":"415","DOI":"10.2340\/0001555560415423","article-title":"Prevalence of skin diseases among adolescents 12-16 years of age","volume":"60","author":"Larsson","year":"1980","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jaad.2011.11.937_bib4","first-page":"797","article-title":"An unusual variety of vitiligo (leukoderma acquisitum centrifugum)","volume":"34","author":"Sutton","year":"1916","journal-title":"J Cutan Dis"},{"key":"10.1016\/j.jaad.2011.11.937_bib5","series-title":"Fitzpatrick\u2019s dermatology in general medicine","first-page":"1105","article-title":"Melanocytic tumors","author":"Grichnik","year":"2008"},{"key":"10.1016\/j.jaad.2011.11.937_bib6","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1001\/archderm.1964.01590270053012","article-title":"The halo nevus","volume":"89","author":"Frank","year":"1964","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2011.11.937_bib7","series-title":"Dermatology","first-page":"1725","article-title":"Benign melanocytic neoplasms","author":"Barnhill","year":"2008"},{"key":"10.1016\/j.jaad.2011.11.937_bib8","series-title":"Lever\u2019s histopathology of the skin","first-page":"747","article-title":"Benign pigmented lesions and malignant melanoma","author":"Elder","year":"1997"},{"key":"10.1016\/j.jaad.2011.11.937_bib9","series-title":"Pathology of the skin","first-page":"1122","article-title":"Chapter 56: Melanocytic tumors","author":"Farmer","year":"2000"},{"key":"10.1016\/j.jaad.2011.11.937_bib10","series-title":"Dermatopathology","first-page":"620","article-title":"Tumors of melanocytes","author":"Barnhill","year":"2010"},{"key":"10.1016\/j.jaad.2011.11.937_bib11","series-title":"Andrews\u2019 diseases of the skin: clinical dermatology","first-page":"680","article-title":"Melanocytic nevi and neoplasms","author":"James","year":"2011"},{"key":"10.1016\/j.jaad.2011.11.937_bib12","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0190-9622(97)70181-6","article-title":"The immune response in halo nevi","volume":"37","author":"Zeff","year":"1997","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2011.11.937_bib13","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3121\/cmr.2.2.89","article-title":"The immunopathology of regression in benign lichenoid keratosis, keratoacanthoma and halo nevus","volume":"2","author":"Bayer-Garner","year":"2004","journal-title":"Clin Med Res"},{"key":"10.1016\/j.jaad.2011.11.937_bib14","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/j.1600-0560.1994.tb00704.x","article-title":"Characterization of the mononuclear infiltrate involved in regression of halo nevi","volume":"21","author":"Akasu","year":"1994","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.jaad.2011.11.937_bib15","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1111\/j.1600-0560.1997.tb01092.x","article-title":"Spitz\u2019s nevi with halo reaction: a histopathologic study of 17 cases","volume":"24","author":"Harvell","year":"1997","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.jaad.2011.11.937_bib16","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/S0190-9622(83)70183-0","article-title":"Malignant melanoma and vitiligo-like leukoderma: an electron microscopic study","volume":"9","author":"Koh","year":"1983","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2011.11.937_bib17","series-title":"Pathology of the skin with clinical correlation","author":"McKee","year":"2005"},{"key":"10.1016\/j.jaad.2011.11.937_bib18","series-title":"Rook\u2019s textbook of dermatology","first-page":"49","article-title":"Disorders of skin color","author":"Anstey","year":"2010"},{"key":"10.1016\/j.jaad.2011.11.937_bib19","doi-asserted-by":"crossref","first-page":"55","DOI":"10.2340\/00015555725557","article-title":"Birthmarks in 4346 Finnish newborns","volume":"72","author":"Karvonen","year":"1991","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jaad.2011.11.937_bib20","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1111\/j.1524-4725.1981.tb00695.x","article-title":"A congenital pigmented nevus associated with leukoderma","volume":"7","author":"Kopf","year":"1981","journal-title":"J Dermatol Surg Oncol"},{"key":"10.1016\/j.jaad.2011.11.937_bib21","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1001\/archderm.1971.04000230057009","article-title":"Multiple congenital giant nevocellular nevi with halo, a clinical and electron microscopic study","volume":"104","author":"Berger","year":"1971","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2011.11.937_bib22","first-page":"866","article-title":"Regression of a congenital giant pigmented nevus of the scalp associated with congenital halo-nevi","volume":"116","author":"Bourgeois-Droin","year":"1989","journal-title":"Ann Dermatol Venereol"},{"key":"10.1016\/j.jaad.2011.11.937_bib23","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1365-2133.1995.tb02512.x","article-title":"Halo congenital nevus","volume":"133","author":"Ridley","year":"1995","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2011.11.937_bib24","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1001\/archderm.1994.01690080102015","article-title":"Halo congenital nevus undergoing spontaneous regression: involvement of T-cell immunity in involution and presence of circulating anti-nevus cell IgM antibodies","volume":"130","author":"Tokura","year":"1994","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2011.11.937_bib25","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1524-4725.1990.tb00051.x","article-title":"Congenital melanocytic nevi with halo phenomenon: report of two cases and a review of the literature","volume":"16","author":"Langer","year":"1990","journal-title":"J Dermatol Surg Oncol"},{"key":"10.1016\/j.jaad.2011.11.937_bib26","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1046\/j.1525-1470.2002.00028.x","article-title":"Acquired leukoderma in congenital pigmented nevus associated with vitiligo-like depigmentation","volume":"19","author":"Itin","year":"2002","journal-title":"Pediatr Dermatol"},{"key":"10.1016\/j.jaad.2011.11.937_bib27","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1001\/jama.1973.03220310013003","article-title":"Halo nevi and melanoma","volume":"225","author":"Epstein","year":"1973","journal-title":"JAMA"},{"key":"10.1016\/j.jaad.2011.11.937_bib28","first-page":"338","article-title":"Halo congenital nevus","volume":"23","author":"Garcia","year":"1979","journal-title":"Cutis"},{"key":"10.1016\/j.jaad.2011.11.937_bib29","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1159\/000247431","article-title":"Leukoderma in association with giant congenital nevi: report of two cases","volume":"185","author":"Albert","year":"1992","journal-title":"Dermatology"},{"key":"10.1016\/j.jaad.2011.11.937_bib30","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1159\/000246823","article-title":"Very late metastasis (27 years) of cutaneous malignant melanoma arising in a halo giant congenital nevus","volume":"189","author":"Bouffard","year":"1994","journal-title":"Dermatology"},{"key":"10.1016\/j.jaad.2011.11.937_bib31","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.4049\/jimmunol.162.3.1789","article-title":"Immune-mediated destruction of melanocytes in halo nevi is associated with the local expansion of a limited number of T cell clones","volume":"162","author":"Musette","year":"1999","journal-title":"J Immunol"},{"key":"10.1016\/j.jaad.2011.11.937_bib32","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s00403-003-0427-2","article-title":"Molecular evidence that halo in Sutton\u2019s nevus is not vitiligo","volume":"295","author":"Schallreuter","year":"2003","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.jaad.2011.11.937_bib33","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1001\/archderm.142.12.1627","article-title":"Dermoscopy patterns of halo nevi","volume":"142","author":"Kolm","year":"2006","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2011.11.937_bib34","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1111\/j.1365-2230.2008.03030.x","article-title":"Melanoma with halo","volume":"34","author":"Rubegni","year":"2009","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.jaad.2011.11.937_bib35","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1159\/000051666","article-title":"Unusual halo nevi\u2013darkening rather than lightening of the central nevus","volume":"202","author":"Huynh","year":"2001","journal-title":"Dermatology"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962211022468?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962211022468?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:22:33Z","timestamp":1759270953000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962211022468"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0190962211022468"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2011.11.937","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The natural history of halo nevi: A retrospective case series","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2011.11.937","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}