{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:48:24Z","timestamp":1759333704249,"version":"build-2065373602"},"reference-count":37,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1016\/j.jaad.2013.08.017","type":"journal-article","created":{"date-parts":[[2013,10,2]],"date-time":"2013-10-02T01:20:07Z","timestamp":1380676807000},"page":"947-953","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Frequency of melanocytic nevi in psoriatic patients is\u00a0related to treatment and not to disease severity"],"prefix":"10.1016","volume":"69","author":[{"given":"Antonella","family":"Di Cesare","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Assunta","family":"Riitano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariano","family":"Suppa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosaria","family":"Fidanza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arianna","family":"Zangrilli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Esposito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Concetta","family":"Fargnoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Chimenti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ketty","family":"Peris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaad.2013.08.017_bib1","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1056\/NEJMra0804595","article-title":"Psoriasis","volume":"361","author":"Nestle","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaad.2013.08.017_bib2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1365-2133.2012.11208.x","article-title":"Long-term safety of biologics in the treatment of moderate-to-severe plaque psoriasis: review of current data","volume":"167","author":"Rustin","year":"2012","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib3","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.2165\/11634980-000000000-00000","article-title":"Current and emerging systemic treatment strategies for psoriasis","volume":"72","author":"Laws","year":"2012","journal-title":"Drugs"},{"key":"10.1016\/j.jaad.2013.08.017_bib4","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1177\/039463201002300212","article-title":"Continuous treatment of plaque-type psoriasis with etanercept: an observational long-term experience","volume":"23","author":"Esposito","year":"2010","journal-title":"Int J Immunopathol Pharmacol"},{"key":"10.1016\/j.jaad.2013.08.017_bib5","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.1158\/1055-9965.EPI-07-2801","article-title":"Sun exposure and the incidence of melanocytic nevi in young Australian children","volume":"17","author":"Harrison","year":"2008","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.jaad.2013.08.017_bib6","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1046\/j.1523-1747.2003.12246.x","article-title":"The influence of painful sunburns and lifetime sun exposure on the risk of actinic keratoses, seborrheic warts, melanocytic nevi, atypical nevi and skin cancer","volume":"120","author":"Kennedy","year":"2003","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib7","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1001\/archdermatol.2010.145","article-title":"Eruptive nevi in patient receiving cyclosporine A for psoriasis treatment","volume":"146","author":"Lopez","year":"2010","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib8","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1159\/000246050","article-title":"Excess melanocytic nevi in renal transplant recipients","volume":"194","author":"Szepietowski","year":"1997","journal-title":"Dermatology"},{"key":"10.1016\/j.jaad.2013.08.017_bib9","first-page":"880","article-title":"Induction of eruptive benign melanocytic nevi by immune suppressive agents, including biologicals","volume":"154","author":"Bovenschen","year":"2006","journal-title":"Br\u00a0J\u00a0Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib10","first-page":"563","article-title":"Psoriasis and the metabolic syndrome","volume":"7","author":"Gottlieb","year":"2008","journal-title":"J Drugs Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib11","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1159\/000342180","article-title":"Psoriasis comorbidities: result from the National Psoriasis Foundation surveys 2003 to 2011","volume":"225","author":"Armstrong","year":"2012","journal-title":"Dermatology"},{"key":"10.1016\/j.jaad.2013.08.017_bib12","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2165\/00128071-200506060-00005","article-title":"The psychosocial burden of psoriasis","volume":"6","author":"Kimball","year":"2005","journal-title":"Am J Clin Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib13","doi-asserted-by":"crossref","first-page":"2604","DOI":"10.1038\/jid.2009.113","article-title":"Psoriasis and risk of incident cancer: an inception cohort study with a nested case-control analysis","volume":"129","author":"Brauchli","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib14","first-page":"1003","article-title":"Association between psoriasis and incident cancer: the Iowa's women's health study","volume":"22","author":"Prizment","year":"2011","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.jaad.2013.08.017_bib15","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1001\/archderm.140.12.1471","article-title":"Fewer melanocytic nevi found in children with active atopic dermatitis than in children without dermatitis","volume":"140","author":"Synnerstad","year":"2004","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib16","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.1468-3083.2005.01379.x","article-title":"Frequency and distribution pattern of melanocytic nevi in Estonian children and the influence of atopic dermatitis","volume":"20","author":"Kallas","year":"2006","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.jaad.2013.08.017_bib17","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1111\/j.1468-3083.2008.02888.x","article-title":"Low risk of melanoma in patients with atopic dermatitis","volume":"22","author":"Synnerstad","year":"2008","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.jaad.2013.08.017_bib18","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1046\/j.1365-2133.2000.03302.x","article-title":"Atopic dermatitis and melanocytic nevi","volume":"142","author":"Broberg","year":"2000","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib19","first-page":"1262","article-title":"Psoriasis and melanocytic nevi: does the first confer a\u00a0protective role against melanocyte progression to nevi?","volume":"164","author":"Balato","year":"2011","journal-title":"Br\u00a0J\u00a0Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib20","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jaad.2001.11.001","article-title":"Dermoscopy of pigmented skin lesions","volume":"52","author":"Braun","year":"2005","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib21","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1365-2133.1992.tb14818.x","article-title":"Smoking habits in psoriasis: a case control study","volume":"127","author":"Mills","year":"1992","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib22","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1684\/ejd.2009.0644","article-title":"Risk factors of hypertension, diabetes and\u00a0obesity in Italian psoriasis patients: a survey on socio-demographic characteristics, smoking habits and alcohol consumption","volume":"19","author":"Altobelli","year":"2009","journal-title":"Eur J Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib23","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/1523-1747.ep12460991","article-title":"Interleukins 1 alpha and 6 and tumor necrosis factor-alpha are paracrine inhibitors of human melanocyte proliferation and melanogenesis","volume":"96","author":"Swope","year":"1991","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib24","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1046\/j.1432-1327.1998.2550139.x","article-title":"Mechanisms of melanogenesis inhibition by tumor necrosis factor-B in B16\/F10 mouse melanoma cells","volume":"255","author":"Mart\u00ednez-Esparza","year":"1998","journal-title":"Eur J Biochem"},{"key":"10.1016\/j.jaad.2013.08.017_bib25","first-page":"991","article-title":"Independent regulation of tyrosinase by the hypopigmenting cytokines TGF beta1 and TNF alpha and the melanogenic hormone alpha-MSH in B16 mouse melanocytes","volume":"45","author":"Mart\u00ednez-Esparza","year":"1999","journal-title":"Cell Mol Biol"},{"key":"10.1016\/j.jaad.2013.08.017_bib26","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1365-2133.2010.10149.x","article-title":"Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis","volume":"164","author":"S\u00f8yland","year":"2011","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib27","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.4049\/jimmunol.180.3.1913","article-title":"Identification of cellular pathways of\u00a0\u201ctype 1,\u201d Th17 T cells, and TNF- and inducible nitric oxide\u00a0synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis","volume":"180","author":"Haider","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.jaad.2013.08.017_bib28","doi-asserted-by":"crossref","first-page":"2721","DOI":"10.4049\/jimmunol.175.4.2721","article-title":"TNF inhibition rapidly down-regulates multiple proinflammatory pathways in psoriasis patients","volume":"175","author":"Gottlieb","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.jaad.2013.08.017_bib29","doi-asserted-by":"crossref","first-page":"535","DOI":"10.4161\/mabs.3.6.17815","article-title":"Discovery and mechanism of action of\u00a0ustekinumab: a human monoclonal antibody targeting interleukin-12 and interleukin-23 for treatment of immune-mediated disorders","volume":"3","author":"Benson","year":"2011","journal-title":"MAbs"},{"key":"10.1016\/j.jaad.2013.08.017_bib30","doi-asserted-by":"crossref","first-page":"e48991","DOI":"10.1371\/journal.pone.0048991","article-title":"Cancer risk of anti-TNF\u03b1 at recommended doses in adult rheumatoid arthritis: a meta-analysis with intention to treat and per protocol analyses","volume":"2","author":"Moulis","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jaad.2013.08.017_bib31","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.jaad.2008.12.031","article-title":"Treatments for psoriasis and risk of malignancies","volume":"60","author":"Patel","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib32","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1159\/000300136","article-title":"Development of two primary malignant melanomas after treatment with adalimumab: a case report and review of the possible link between biological therapy with anti-TNF-alpha antagonists and melanocytic proliferation","volume":"221","author":"Katoulis","year":"2010","journal-title":"Dermatology"},{"key":"10.1016\/j.jaad.2013.08.017_bib33","first-page":"12","article-title":"Cutaneous melanoma in patients treated with biologic therapy: review of the literature and case report","volume":"17","author":"Manganoni","year":"2011","journal-title":"Dermatology Online J"},{"key":"10.1016\/j.jaad.2013.08.017_bib34","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s10067-012-2114-1","article-title":"Nodular progression of lentigo malignant melanoma during a treatment with tocilizumab: cause or coincidence?","volume":"32","author":"Finet","year":"2013","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib35","doi-asserted-by":"crossref","first-page":"e78","DOI":"10.1016\/j.jaad.2011.08.033","article-title":"Rapidly progressive malignant melanoma in a patient treated with tocilizumab","volume":"67","author":"Bonny","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2013.08.017_bib36","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/art.37740","article-title":"Tumor necrosis factor \u03b1 inhibitor therapy and cancer risk in chronic immune-mediated diseases","volume":"65","author":"Haynes","year":"2013","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jaad.2013.08.017_bib37","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.jaad.2012.10.055","article-title":"OBSERVE-5 interim analysis: an observational postmarketing safety registry of etanercept for the treatment of psoriasis","volume":"68","author":"Kimball","year":"2013","journal-title":"J Am Acad Dermatol"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962213008906?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962213008906?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:28:03Z","timestamp":1759271283000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962213008906"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S0190962213008906"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2013.08.017","relation":{},"ISSN":["0190-9622"],"issn-type":[{"type":"print","value":"0190-9622"}],"subject":[],"published":{"date-parts":[[2013,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Frequency of melanocytic nevi in psoriatic patients is\u00a0related to treatment and not to disease severity","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2013.08.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}