{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:29:01Z","timestamp":1790357341176,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.jaad.2015.08.034","type":"journal-article","created":{"date-parts":[[2015,10,2]],"date-time":"2015-10-02T05:10:12Z","timestamp":1443762612000},"page":"108-119.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Can oral nonsteroidal antiinflammatory drugs play a role in the prevention of basal cell carcinoma? A systematic review and metaanalysis"],"prefix":"10.1016","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6186-533X","authenticated-orcid":false,"given":"Chiho","family":"Muranushi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine M.","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ad\u00e8le C.","family":"Green","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirmala","family":"Pandeya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaad.2015.08.034_bib1","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1111\/j.1365-2133.2012.10830.x","article-title":"A systematic review of worldwide incidence of nonmelanoma skin cancer","volume":"166","author":"Lomas","year":"2012","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2015.08.034_bib2","doi-asserted-by":"crossref","first-page":"565","DOI":"10.5694\/mja12.10654","article-title":"Non-melanoma skin cancer in Australia","volume":"197","author":"Fransen","year":"2012","journal-title":"Med J Aust"},{"key":"10.1016\/j.jaad.2015.08.034_bib3","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1158\/1055-9965.EPI-08-1211","article-title":"Serum antioxidants and skin cancer risk: an 8-year community-based follow-up study","volume":"18","author":"van der Pols","year":"2009","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.jaad.2015.08.034_bib4","first-page":"559","article-title":"Aspirin, ibuprofen, and other non-steroidal anti-inflammatory drugs in cancer prevention: a critical review of non-selective COX-2 blockade (review)","volume":"13","author":"Harris","year":"2005","journal-title":"Oncol Rep"},{"key":"10.1016\/j.jaad.2015.08.034_bib5","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/s10549-011-1747-0","article-title":"Aspirin use and breast cancer risk: a meta-analysis","volume":"131","author":"Luo","year":"2012","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.jaad.2015.08.034_bib6","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1093\/jnci\/djq442","article-title":"Chemoprevention of nonmelanoma skin cancer with celecoxib: a randomized, double-blind, placebo-controlled trial","volume":"102","author":"Elmets","year":"2010","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.jaad.2015.08.034_bib7","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1002\/pds.2142","article-title":"Association between non-steroidal anti-inflammatory drugs and keratinocyte carcinomas of the skin among participants in the Veterans Affairs Topical Tretinoin Chemoprevention Trial","volume":"20","author":"Nunes","year":"2011","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1016\/j.jaad.2015.08.034_bib8","doi-asserted-by":"crossref","first-page":"e96887","DOI":"10.1371\/journal.pone.0096887","article-title":"No chemopreventive effect of nonsteroidal anti-inflammatory drugs on nonmelanoma skin cancer: evidence from meta-analysis","volume":"9","author":"Zhang","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jaad.2015.08.034_bib9","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.3892\/ol.2015.2853","article-title":"Aspirin for the primary prevention of skin cancer: A meta-analysis","volume":"9","author":"Zhu","year":"2015","journal-title":"Oncol Lett"},{"key":"10.1016\/j.jaad.2015.08.034_bib10","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ypmed.2014.08.024","article-title":"Non-melanoma skin cancer and NSAID use in women with a history of skin cancer in the Women\u2019s Health Initiative","volume":"69","author":"Wysong","year":"2014","journal-title":"Prev Med"},{"key":"10.1016\/j.jaad.2015.08.034_bib11","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1001\/jama.283.15.2008","article-title":"Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group","volume":"283","author":"Stroup","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.jaad.2015.08.034_bib12","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1742-7622-5-23","article-title":"Development of a quality assessment tool for systematic reviews of observational studies (QATSO) of HIV prevalence in men having sex with men and associated risk behaviours","volume":"5","author":"Wong","year":"2008","journal-title":"Emerg Themes Epidemiol"},{"key":"10.1016\/j.jaad.2015.08.034_bib13","doi-asserted-by":"crossref","first-page":"W163","DOI":"10.7326\/0003-4819-147-8-200710160-00010-w1","article-title":"Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration","volume":"147","author":"Vandenbroucke","year":"2007","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jaad.2015.08.034_bib14","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.jaad.2015.08.034_bib15","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2307\/3001666","article-title":"The combination of estimates from different experiments","volume":"10","author":"Cochran","year":"1954","journal-title":"Biometrics"},{"key":"10.1016\/j.jaad.2015.08.034_bib16","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.jaad.2015.08.034_bib17","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.2307\/2533446","article-title":"Operating characteristics of a rank correlation test for publication bias","volume":"50","author":"Begg","year":"1994","journal-title":"Biometrics"},{"key":"10.1016\/j.jaad.2015.08.034_bib18","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.jaad.2015.08.034_bib19","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1002\/sim.3013","article-title":"Facilitating meta-analyses by deriving relative effect and precision estimates for alternative comparisons from a set of estimates presented by exposure level or disease category","volume":"27","author":"Hamling","year":"2008","journal-title":"Stat Med"},{"key":"10.1016\/j.jaad.2015.08.034_bib20","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1002\/ijc.26286","article-title":"Use of nonsteroidal anti-inflammatory drugs and risk of basal cell carcinoma in the United States radiologic technologists study","volume":"130","author":"Cahoon","year":"2012","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jaad.2015.08.034_bib21","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1002\/pds.1718","article-title":"Effect of non-steroidal anti-inflammatory drugs on non-melanoma skin cancer incidence in the SKICAP-AK trial","volume":"18","author":"Clouser","year":"2009","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1016\/j.jaad.2015.08.034_bib22","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1002\/ijc.21878","article-title":"Effect of NSAIDs on the recurrence of nonmelanoma skin cancer","volume":"119","author":"Grau","year":"2006","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jaad.2015.08.034_bib23","first-page":"1451","article-title":"Non-steroidal anti-inflammatory drugs, acetaminophen, and risk of skin cancer in the Nurses\u2019 Health Study","volume":"23","author":"Jeter","year":"2012","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.jaad.2015.08.034_bib24","doi-asserted-by":"crossref","first-page":"4768","DOI":"10.1002\/cncr.27406","article-title":"Nonsteroidal anti-inflammatory drugs and the risk of skin cancer: a population-based case-control study","volume":"118","author":"Johannesdottir","year":"2012","journal-title":"Cancer"},{"key":"10.1016\/j.jaad.2015.08.034_bib25","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1046\/j.1365-2133.2003.05352.x","article-title":"Lifestyle differences in twin pairs discordant for basal cell carcinoma of the skin","volume":"149","author":"Milan","year":"2003","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2015.08.034_bib26","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.jaad.2010.05.042","article-title":"Analgesic and nonsteroidal anti-inflammatory use in relation to nonmelanoma skin cancer: a population-based case-control study","volume":"65","author":"Torti","year":"2011","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2015.08.034_bib27","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/ijc.28634","article-title":"Incident cancer risk after the start of aspirin use: results from a Dutch population-based cohort study of low dose aspirin users","volume":"135","author":"Hollestein","year":"2014","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jaad.2015.08.034_bib28","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/ijc.29357","article-title":"Nonsteroidal anti-inflammatory drugs and the risk of nonmelanoma skin cancer","volume":"137","author":"Reinau","year":"2015","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jaad.2015.08.034_bib29","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1684\/ejd.2011.1625","article-title":"Effect of non-steroidal anti-inflammatory drugs on the histology of basal cell carcinomas","volume":"22","author":"Husein-El-Ahmed","year":"2012","journal-title":"Eur J Dermatol"},{"key":"10.1016\/j.jaad.2015.08.034_bib30","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1158\/1940-6207.CAPR-09-0200","article-title":"Basal cell carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in genetically predisposed PTCH1+\/\u2212 humans and mice","volume":"3","author":"Tang","year":"2010","journal-title":"Cancer Prev Res"},{"key":"10.1016\/j.jaad.2015.08.034_bib31","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.mrfmmm.2007.01.005","article-title":"Polymorphisms in COX-2, NSAID use and risk of basal cell carcinoma in a prospective study of Danes","volume":"617","author":"Vogel","year":"2007","journal-title":"Mutat Res"},{"key":"10.1016\/j.jaad.2015.08.034_bib32","doi-asserted-by":"crossref","first-page":"2901","DOI":"10.1038\/sj.jid.5700934","article-title":"Reported use of photosensitizing medications and basal cell and squamous cell carcinoma of the skin: results of a population-based case-control study","volume":"127","author":"Karagas","year":"2007","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaad.2015.08.034_bib33","first-page":"13","article-title":"Methodological issues in using prescription and other databases in pharmacoepidemiology","volume":"11","author":"S\u00f8rensen","year":"2001","journal-title":"Norsk Epidemiologi"},{"key":"10.1016\/j.jaad.2015.08.034_bib34","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1093\/oxfordjournals.aje.a117563","article-title":"Recall accuracy for prescription medications: self-report compared with database information","volume":"142","author":"West","year":"1995","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jaad.2015.08.034_bib35","doi-asserted-by":"crossref","first-page":"R216","DOI":"10.1186\/ar3195","article-title":"Vitamin D deficiency in rheumatoid arthritis: prevalence, determinants and associations with disease activity and disability","volume":"12","author":"Rossini","year":"2010","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.jaad.2015.08.034_bib36","first-page":"3147","article-title":"Non-steroidal anti-inflammatory drugs in cancer prevention and therapy","volume":"27","author":"Guadagni","year":"2007","journal-title":"Anticancer Res"},{"key":"10.1016\/j.jaad.2015.08.034_bib37","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1592\/phco.23.1.9.31916","article-title":"Selective cyclooxygenase-2 inhibition: a target in cancer prevention and treatment","volume":"23","author":"Subongkot","year":"2003","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.jaad.2015.08.034_bib38","doi-asserted-by":"crossref","first-page":"380","DOI":"10.3109\/09546634.2012.674191","article-title":"Immunohistochemical study of cyclooxygenase-2 in skin tumors","volume":"25","author":"Amirnia","year":"2014","journal-title":"J Dermatolog Treat"},{"key":"10.1016\/j.jaad.2015.08.034_bib39","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1038\/jid.2014.531","article-title":"Aspirin and nonsteroidal anti-inflammatory drugs can prevent cutaneous squamous cell carcinoma: a systematic review and meta-analysis","volume":"135","author":"Muranushi","year":"2015","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jaad.2015.08.034_bib40","doi-asserted-by":"crossref","first-page":"345","DOI":"10.2165\/00002018-200225050-00004","article-title":"Drug-induced cutaneous photosensitivity: incidence, mechanism, prevention and management","volume":"25","author":"Moore","year":"2002","journal-title":"Drug Saf"},{"key":"10.1016\/j.jaad.2015.08.034_bib41","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0378-4274(98)00237-9","article-title":"Photocarcinogenicity of drugs","volume":"102-103","author":"Stern","year":"1998","journal-title":"Toxicol Lett"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962215020769?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962215020769?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:35:14Z","timestamp":1759271714000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962215020769"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["S0190962215020769"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2015.08.034","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Can oral nonsteroidal antiinflammatory drugs play a role in the prevention of basal cell carcinoma? A systematic review and metaanalysis","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2015.08.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}