{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T04:16:59Z","timestamp":1790223419903,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1016\/j.jaad.2015.12.018","type":"journal-article","created":{"date-parts":[[2016,2,12]],"date-time":"2016-02-12T10:43:28Z","timestamp":1455273808000},"page":"870-877","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"title":["Cutaneous T-cell lymphoma (CTCL): Current practices in blood assessment and the utility of T-cell receptor (TCR)-V\u03b2 chain restriction"],"prefix":"10.1016","volume":"74","author":[{"given":"Juliet F.","family":"Gibson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina J.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kacie R.","family":"Carlson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francine","family":"Foss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaehyuk","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Edelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerry W.","family":"Hussong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramsey","family":"Mohl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally","family":"Hill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Girardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jaad.2015.12.018_bib1","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1172\/JCI24826","article-title":"Immunopathogenesis and therapy of cutaneous T cell lymphoma","volume":"115","author":"Kim","year":"2005","journal-title":"J Clin Invest"},{"issue":"7","key":"10.1016\/j.jaad.2015.12.018_bib2","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1001\/archderm.139.7.857","article-title":"Long-term outcome of 525 patients with mycosis fungoides and S\u00e9zary syndrome: clinical prognostic factors and risk for disease progression","volume":"139","author":"Kim","year":"2003","journal-title":"Arch Dermatol"},{"issue":"3","key":"10.1016\/j.jaad.2015.12.018_bib3","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1182\/blood.V97.3.624","article-title":"Prognostic significance of tumor burden in the blood of patients with erythrodermic primary cutaneous T-cell lymphoma","volume":"97","author":"Scarisbrick","year":"2001","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.jaad.2015.12.018_bib4","first-page":"571","article-title":"Blood and lymph node T lymphocytes in cutaneous T cell lymphoma: evaluation by light microscopy","volume":"63","author":"Schechter","year":"1979","journal-title":"Cancer Treat Rep"},{"issue":"6","key":"10.1016\/j.jaad.2015.12.018_bib5","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1182\/blood-2007-03-055749","volume":"110","author":"Olsen","year":"2007","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.jaad.2015.12.018_bib6","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1111\/j.1365-2133.2008.08739.x","article-title":"The diagnosis of S\u00e9zary syndrome on peripheral blood by flow cytometry requires the use of multiple markers","volume":"159","author":"Klemke","year":"2008","journal-title":"Br J Dermatol"},{"issue":"2","key":"10.1016\/j.jaad.2015.12.018_bib7","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1001\/archderm.1994.01690020064010","article-title":"Profound deficiency in normal\u00a0circulating T cells in erythrodermic cutaneous T-cell lymphoma","volume":"130","author":"Heald","year":"1994","journal-title":"Arch Dermatol"},{"issue":"3 Pt 1","key":"10.1016\/j.jaad.2015.12.018_bib8","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/S0190-9622(96)90605-2","article-title":"Detection\u00a0of circulating T cells with CD4+ CD7\u2013 immunophenotype in patients with benign and malignant lymphoproliferative dermatoses","volume":"35","author":"Harmon","year":"1996","journal-title":"J Am Acad Dermatol"},{"issue":"3","key":"10.1016\/j.jaad.2015.12.018_bib9","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1172\/JCI112393","article-title":"Defective expression of T cell-associated glycoprotein in severe combined immunodeficiency","volume":"77","author":"Jung","year":"1986","journal-title":"J Clin Invest"},{"issue":"5","key":"10.1016\/j.jaad.2015.12.018_bib10","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.4049\/jimmunol.150.5.2081","article-title":"CD7\u2013 T cells represent a subset of normal human blood lymphocytes","volume":"150","author":"Reinhold","year":"1993","journal-title":"J Immunol"},{"issue":"4","key":"10.1016\/j.jaad.2015.12.018_bib11","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1046\/j.1365-2133.2003.05224.x","article-title":"The relevance of peripheral blood T-helper 1 and 2 cytokine pattern in the evaluation of patients with mycosis fungoides and S\u00e9zary syndrome","volume":"148","author":"Papadavid","year":"2003","journal-title":"Br J Dermatol"},{"issue":"6","key":"10.1016\/j.jaad.2015.12.018_bib12","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/S0889-8588(03)00120-5","article-title":"The S\u00e9zary syndrome: hematologic criteria","volume":"17","author":"Vonderheid","year":"2003","journal-title":"Hematol Oncol Clin North Am"},{"issue":"9","key":"10.1016\/j.jaad.2015.12.018_bib13","doi-asserted-by":"crossref","first-page":"2987","DOI":"10.1182\/blood.V96.9.2987","article-title":"Diagnostic value of dominant T-cell clones in peripheral blood in 363 patients presenting consecutively with a clinical suspicion of cutaneous lymphoma","volume":"96","author":"Delfau-Larue","year":"2000","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.jaad.2015.12.018_bib14","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1182\/blood.V90.4.1636","article-title":"Demonstration of frequent occurrence of clonal T cells in the peripheral blood of patients with primary cutaneous T-cell lymphoma","volume":"90","author":"Muche","year":"1997","journal-title":"Blood"},{"issue":"Suppl 1","key":"10.1016\/j.jaad.2015.12.018_bib15","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.0303-6987.2006.00541.x","article-title":"On the diagnosis of erythrodermic cutaneous T-cell lymphoma","volume":"33","author":"Vonderheid","year":"2006","journal-title":"J Cutan Pathol"},{"issue":"3","key":"10.1016\/j.jaad.2015.12.018_bib16","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1309\/3A32DTVMH640M2QA","article-title":"Flow cytometric assessment of TCR-Vbeta expression in the evaluation of peripheral blood involvement by T-cell lymphoproliferative disorders: a comparison with conventional T-cell immunophenotyping and molecular genetic techniques","volume":"121","author":"Morice","year":"2004","journal-title":"Am J Clin Pathol"},{"issue":"2","key":"10.1016\/j.jaad.2015.12.018_bib17","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1038\/modpathol.2009.175","article-title":"Flow cytometric detection of peripheral blood involvement by mycosis fungoides and S\u00e9zary syndrome using T-cell receptor Vbeta chain antibodies and its application in blood staging","volume":"23","author":"Feng","year":"2010","journal-title":"Mod Pathol"},{"issue":"5","key":"10.1016\/j.jaad.2015.12.018_bib18","first-page":"1477","article-title":"Failure of anti-T-cell receptor V beta antibodies to consistently identify a malignant T-cell clone in S\u00e9zary syndrome","volume":"149","author":"Bigler","year":"1996","journal-title":"Am J Pathol"},{"issue":"3","key":"10.1016\/j.jaad.2015.12.018_bib19","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/j.0022-202X.2004.23586.x","article-title":"Evidence for restricted Vbeta usage in the leukemic phase of cutaneous T cell lymphoma","volume":"124","author":"Vonderheid","year":"2005","journal-title":"J Invest Dermatol"},{"issue":"3","key":"10.1016\/j.jaad.2015.12.018_bib20","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1309\/25E9Y7RRAY84HTAT","article-title":"A comparison of morphologic features, flow cytometry, TCR-Vbeta analysis, and TCR-PCR in qualitative and quantitative assessment of peripheral blood involvement by S\u00e9zary syndrome","volume":"125","author":"Morice","year":"2006","journal-title":"Am J Clin Pathol"},{"issue":"18","key":"10.1016\/j.jaad.2015.12.018_bib21","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1200\/JCO.2010.32.0630","volume":"2","author":"Olsen","year":"2011","journal-title":"J Clin Oncol"},{"issue":"3","key":"10.1016\/j.jaad.2015.12.018_bib22","first-page":"173","article-title":"A simplified method of detection of clonal rearrangements of the T-cell receptor-gamma chain gene","volume":"1","author":"McCarthy","year":"1992","journal-title":"Diagn Mol Pathol"},{"issue":"4","key":"10.1016\/j.jaad.2015.12.018_bib23","first-page":"821","article-title":"The rapid detection of clonal T-cell proliferations in patients with lymphoid disorders","volume":"138","author":"McCarthy","year":"1991","journal-title":"Am J Pathol"},{"issue":"1","key":"10.1016\/j.jaad.2015.12.018_bib24","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1046\/j.1365-2133.2001.04014.x","article-title":"The relevance of the CD4+ CD26\u2013 subset in the identification of circulating S\u00e9zary cells","volume":"144","author":"Bernengo","year":"2001","journal-title":"Br J Dermatol"},{"issue":"7","key":"10.1016\/j.jaad.2015.12.018_bib25","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1001\/archderm.139.7.909","article-title":"Monitoring the decrease of circulating malignant T cells in cutaneous T-cell lymphoma during photopheresis and interferon therapy","volume":"139","author":"Ferenczi","year":"2003","journal-title":"Arch Dermatol"},{"issue":"4","key":"10.1016\/j.jaad.2015.12.018_bib26","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1046\/j.1365-2141.2002.03726.x","article-title":"The use of anti-T-cell receptor-Vbeta antibodies for the estimation of treatment success and phenotypic characterization of clonal T-cell populations in cutaneous T-cell lymphomas","volume":"118","author":"Schwab","year":"2002","journal-title":"Br J Haematol"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962215025694?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962215025694?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:39:42Z","timestamp":1759271982000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962215025694"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["S0190962215025694"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2015.12.018","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2016,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cutaneous T-cell lymphoma (CTCL): Current practices in blood assessment and the utility of T-cell receptor (TCR)-V\u03b2 chain restriction","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2015.12.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}