{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T01:09:03Z","timestamp":1789693743620,"version":"4.0.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.jaad.2016.02.1220","type":"journal-article","created":{"date-parts":[[2016,4,7]],"date-time":"2016-04-07T06:05:39Z","timestamp":1460009139000},"page":"155-162","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":90,"title":["Dietary glycemic factors, insulin resistance, and adiponectin levels in acne vulgaris"],"prefix":"10.1016","volume":"75","author":[{"given":"Asl\u0131 Aksu","family":"\u00c7erman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ezgi","family":"Akta\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130lknur K\u0131van\u00e7","family":"Altunay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janset Erkul","family":"Ar\u0131c\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ays\u0131n","family":"Tulunay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feyza Yener","family":"Ozturk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaad.2016.02.1220_bib1","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.jaad.2009.01.019","article-title":"New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne Group","volume":"60","author":"Thiboutot","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib2","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1111\/j.1365-4632.2009.04002.x","article-title":"Diet and acne: a review of the evidence","volume":"48","author":"Spencer","year":"2009","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib3","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.clindermatol.2010.03.017","article-title":"Nutrition and acne","volume":"28","author":"Danby","year":"2010","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib4","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.jaad.2009.07.043","article-title":"Diet and acne","volume":"63","author":"Bowe","year":"2010","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib5","doi-asserted-by":"crossref","first-page":"20","DOI":"10.4161\/derm.19828","article-title":"Dietary intervention in acne: attenuation of increased mTORC1 signaling promoted by Western diet","volume":"4","author":"Melnik","year":"2012","journal-title":"Dermatoendocrinol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib6","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.sder.2005.04.002","article-title":"Implications for the role of diet in acne","volume":"24","author":"Cordain","year":"2005","journal-title":"Semin Cutan Med Surg"},{"key":"10.1016\/j.jaad.2016.02.1220_bib7","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S1095-6433(03)00011-4","article-title":"Hyperinsulinemic diseases of civilization: more than just syndrome X","volume":"136","author":"Cordain","year":"2003","journal-title":"Comp Biochem Physiol\u00a0A Mol Integr Physiol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib8","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1001\/archderm.138.12.1584","article-title":"Acne vulgaris: a disease of Western civilization","volume":"138","author":"Cordain","year":"2002","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib9","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1111\/j.1600-0625.2009.00924.x","article-title":"Role of insulin, insulin-like growth factor-1, hyperglycemic food and milk consumption in the pathogenesis of acne vulgaris","volume":"18","author":"Melnik","year":"2009","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib10","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1093\/ajcn\/86.1.107","article-title":"A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial","volume":"86","author":"Smith","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jaad.2016.02.1220_bib11","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1056\/NEJM199509283331307","article-title":"Polycystic ovary syndrome","volume":"333","author":"Franks","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaad.2016.02.1220_bib12","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.atherosclerosis.2014.01.051","article-title":"Modulation of adiponectin as a potential therapeutic strategy","volume":"233","author":"Lim","year":"2014","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jaad.2016.02.1220_bib13","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.cca.2007.01.026","article-title":"Adiponectin as an anti-inflammatory factor","volume":"380","author":"Ouchi","year":"2007","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.jaad.2016.02.1220_bib14","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1093\/ajcn\/81.4.780","article-title":"Association between dietary factors and plasma adiponectin concentrations in men","volume":"81","author":"Pischon","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jaad.2016.02.1220_bib15","first-page":"241","article-title":"Plasma adiponectin concentrations are associated with dietary glycemic index in Malaysian patients with type 2 diabetes","volume":"22","author":"Loh","year":"2013","journal-title":"Asia Pac J Clin Nutr"},{"key":"10.1016\/j.jaad.2016.02.1220_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cyto.2013.06.317","article-title":"Adiponectin in inflammatory and immune-mediated diseases","volume":"64","author":"Fantuzzi","year":"2013","journal-title":"Cytokine"},{"key":"10.1016\/j.jaad.2016.02.1220_bib17","doi-asserted-by":"crossref","first-page":"371","DOI":"10.2147\/CCID.S69135","article-title":"Linking diet to acne metabolomics, inflammation, and comedogenesis: an update","volume":"8","author":"Melnik","year":"2015","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib18","series-title":"Acne: causes and practical management","first-page":"49","author":"Danby","year":"2015"},{"key":"10.1016\/j.jaad.2016.02.1220_bib19","doi-asserted-by":"crossref","first-page":"644","DOI":"10.2340\/00015555-1677","article-title":"Acne: risk indicator for increased body mass index and insulin resistance","volume":"93","author":"Melnik","year":"2013","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib20","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/exd.12142","article-title":"Potential role of FoxO1 and mTORC1 in the pathogenesis of Western diet-induced acne","volume":"22","author":"Melnik","year":"2013","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib21","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.jaad.2007.01.046","article-title":"The effect of a high-protein, low glycemic-load diet versus a conventional, high glycemic-load diet on biochemical parameters associated with acne vulgaris: a randomized, investigator-masked, controlled trial","volume":"57","author":"Smith","year":"2007","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib22","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.jand.2013.11.010","article-title":"Relationships of self-reported dietary factors and perceived acne severity in a cohort of\u00a0New\u00a0York young adults","volume":"114","author":"Burris","year":"2014","journal-title":"J Acad Nutr Diet"},{"key":"10.1016\/j.jaad.2016.02.1220_bib23","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.3390\/nu2101060","article-title":"Effect of the glycemic index of carbohydrates on acne vulgaris","volume":"2","author":"Reynolds","year":"2010","journal-title":"Nutrients"},{"key":"10.1016\/j.jaad.2016.02.1220_bib24","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.jaad.2007.06.028","article-title":"Dietary glycemic index and glucose, insulin, insulin-like growth factor-1, insulin like growth factor binding protein-3, and leptin levels in patients with acne","volume":"57","author":"Kaymak","year":"2007","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2016.02.1220_bib25","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.phrs.2014.03.003","article-title":"Back to the heart: the protective role of adiponectin","volume":"82","author":"Caselli","year":"2014","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.jaad.2016.02.1220_bib26","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1186\/2193-1801-3-735","article-title":"Diminished mTOR signaling: a common mode\u00a0of action for endocrine longevity factors","volume":"3","author":"Lamming","year":"2014","journal-title":"Springerplus"},{"key":"10.1016\/j.jaad.2016.02.1220_bib27","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/j.1753-4887.2011.00414.x","article-title":"Effect of diet on adiponectin levels in blood","volume":"69","author":"Silva","year":"2011","journal-title":"Nutr Rev"},{"key":"10.1016\/j.jaad.2016.02.1220_bib28","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s12020-012-9647-6","article-title":"Insulin resistance and acne: a new risk factor for men?","volume":"42","author":"Del Prete","year":"2012","journal-title":"Endocrine"},{"key":"10.1016\/j.jaad.2016.02.1220_bib29","first-page":"1","article-title":"Insulin resistance and metabolic syndrome in young men with acne","volume":"23","author":"Nagpal","year":"2015","journal-title":"JAMA Dermatol"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962216014857?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962216014857?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:38:16Z","timestamp":1759271896000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962216014857"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["S0190962216014857"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2016.02.1220","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dietary glycemic factors, insulin resistance, and adiponectin levels in acne vulgaris","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2016.02.1220","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 by the American Academy of Dermatology, Inc.","name":"copyright","label":"Copyright"}]}}