{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T12:52:31Z","timestamp":1780404751210,"version":"3.54.1"},"reference-count":7,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","jaad.org","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.jaad.2019.01.065","type":"journal-article","created":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T11:19:07Z","timestamp":1549019947000},"page":"e185-e186","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comment on \u201cAnti-aging effects of ingenol mebutate for patients with actinic keratosis\u201d and phenol-croton oil peelings"],"prefix":"10.1016","volume":"80","author":[{"given":"Carlos Gustavo","family":"Wambier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kachiu Cecilia","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas Michael","family":"Bertolini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter P.","family":"Rullan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio Luis","family":"Beltrame","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.jaad.2019.01.065_bib1","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.jaad.2018.05.1244","article-title":"Anti-aging effects of ingenol mebutate for patients with actinic keratosis","volume":"79","author":"Kim","year":"2018","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2019.01.065_bib2","doi-asserted-by":"crossref","unstructured":"Wambier CG, Lee KC, Soon SL, et al. Advanced chemical peels: phenol-croton oil peel. J Am Acad Dermatol. doi: https:\/\/doi.org\/10.1016\/j.jaad.2018.11.060. Accessed February 18, 2019.","DOI":"10.1016\/j.jaad.2018.11.060"},{"issue":"26","key":"10.1016\/j.jaad.2019.01.065_bib3","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1056\/NEJM183308070082602","article-title":"Croton oil","volume":"8","author":"Hutchinson","year":"1833","journal-title":"Boston Med Surg J"},{"issue":"1","key":"10.1016\/j.jaad.2019.01.065_bib4","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/BF01972119","article-title":"\u00dcber den Giftstoff im Kroton\u00f6l","volume":"157","author":"B\u00f6hm","year":"1930","journal-title":"Naunyn Schmiedebergs Arch Exp Pathol Pharmakol"},{"issue":"9","key":"10.1016\/j.jaad.2019.01.065_bib5","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1351\/pac197749091423","article-title":"New toxic, irritant and cocarcinogenic diterpene esters from euphorbiaceae and from thymelaeaceae","volume":"49","author":"Hecker","year":"1977","journal-title":"Pure Appl Chem"},{"key":"10.1016\/j.jaad.2019.01.065_bib6","series-title":"Naturally Occurring Phorbol Esters","author":"Evans","year":"2018"},{"issue":"8","key":"10.1016\/j.jaad.2019.01.065_bib7","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1021\/cr0002801","article-title":"Protein kinase C: Structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions","volume":"101","author":"Newton","year":"2001","journal-title":"Chem Rev"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962219301768?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962219301768?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T22:01:20Z","timestamp":1557957680000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962219301768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S0190962219301768"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2019.01.065","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comment on \u201cAnti-aging effects of ingenol mebutate for patients with actinic keratosis\u201d and phenol-croton oil peelings","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2019.01.065","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2018.05.1244","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 by the American Academy of Dermatology, Inc.","name":"copyright","label":"Copyright"}]}}