{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T03:36:20Z","timestamp":1791948980593,"version":"4.3.4"},"reference-count":77,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1016\/j.jaad.2019.02.047","type":"journal-article","created":{"date-parts":[[2019,2,22]],"date-time":"2019-02-22T14:43:07Z","timestamp":1550846587000},"page":"558-567","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":182,"title":["Management of acute radiation dermatitis: A review of the literature and proposal for treatment algorithm"],"prefix":"10.1016","volume":"81","author":[{"given":"Amanda","family":"Rosenthal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Israilevich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald","family":"Moy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.jaad.2019.02.047_bib1","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/S0360-3016(00)00782-3","article-title":"Randomized phase III study comparing best supportive care to Biafine as a prophylactic agent for radiation-induced skin toxicity for women undergoing breast irradiation","volume":"48","author":"Fisher","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"4","key":"10.1016\/j.jaad.2019.02.047_bib2","doi-asserted-by":"crossref","first-page":"94","DOI":"10.3747\/co.v17i4.493","article-title":"Prophylaxis and\u00a0management of acute radiation-induced skin reactions: a systematic review of the literature","volume":"17","author":"Salvo","year":"2010","journal-title":"Curr Oncol"},{"issue":"4","key":"10.1016\/j.jaad.2019.02.047_bib3","first-page":"16","article-title":"Managing radiotherapy induced skin reactions in the community","volume":"27","author":"Trueman","year":"2013","journal-title":"J Community Nurs"},{"key":"10.1016\/j.jaad.2019.02.047_bib4","series-title":"Principles and Practice of Radiation Oncology","first-page":"320","article-title":"Late effects of cancer treatment on normal tissues","author":"Constine","year":"2007"},{"key":"10.1016\/j.jaad.2019.02.047_bib5","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jaad.2005.08.054","article-title":"Radiation dermatitis: clinical presentation, pathophysiology, and treatment 2006","volume":"54","author":"Hymes","year":"2006","journal-title":"J Am Acad Dermatol"},{"issue":"8","key":"10.1016\/j.jaad.2019.02.047_bib6","first-page":"802","article-title":"Supportive Care Guidelines Group of Cancer Care Ontario Program in Evidence-Based Care. The prevention and management of acute skin reactions related to radiation therapy: a systematic review and practice guideline","volume":"14","author":"Bolderston","year":"2006","journal-title":"Support Care Cancer"},{"issue":"3","key":"10.1016\/j.jaad.2019.02.047_bib7","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.soncn.2006.04.004","article-title":"Evidence-based skin care management in radiation therapy","volume":"22","author":"McQuestion","year":"2006","journal-title":"Semin Oncol Nurs"},{"issue":"2","key":"10.1016\/j.jaad.2019.02.047_bib8","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S0936-6555(05)80971-9","article-title":"Can patients wash during radiotherapy to the breast or chest wall? A randomized controlled trial","volume":"4","author":"Campbell","year":"1992","journal-title":"Clin Oncol"},{"issue":"3","key":"10.1016\/j.jaad.2019.02.047_bib9","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0167-8140(00)00322-4","article-title":"The impact of skin washing with water and soap during breast irradiation: a randomized study","volume":"58","author":"Roy","year":"2001","journal-title":"Radiother Oncol"},{"issue":"3","key":"10.1016\/j.jaad.2019.02.047_bib10","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.clindermatol.2018.03.008","article-title":"Traditional and ethnobotanical dermatology practices in Romania and other Eastern European countries","volume":"36","author":"Gilca","year":"2018","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.jaad.2019.02.047_bib11","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/ptr.2931","article-title":"Evaluation of healing and antimicrobiological effects of herbal therapy on venous leg ulcer: pilot study","volume":"24","author":"Binic","year":"2010","journal-title":"Phytother Res"},{"key":"10.1016\/j.jaad.2019.02.047_bib12","first-page":"126","article-title":"Determination of the wound healing effect of calendula extracts using the scratch assay with 3T3 fibroblasts","volume":"10","author":"Fronza","year":"2009","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.jaad.2019.02.047_bib13","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1200\/JCO.2004.07.063","article-title":"Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer","volume":"22","author":"Pommier","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jaad.2019.02.047_bib14","doi-asserted-by":"crossref","first-page":"574","DOI":"10.3390\/molecules18010574","article-title":"Comparative evaluation of different co-antioxidants on the photochemical- and functional-stability of epigallocatechin-3-gallate in topical creams exposed to simulated sunlight","volume":"18","author":"Scalia","year":"2013","journal-title":"Molecules"},{"key":"10.1016\/j.jaad.2019.02.047_bib15","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1093\/jrr\/rru047","article-title":"Epigallocatechin-3-gallate (EGCG) protects skin cells from ionizing radiation via heme oxygenase-1 (HO-1) overexpression","volume":"55","author":"Zhu","year":"2014","journal-title":"Radiat Res"},{"key":"10.1016\/j.jaad.2019.02.047_bib16","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1002\/ptr.3483","article-title":"Protective role of tea polyphenols in combination against radiation-induced haematopoietic and biochemical alterations in mice","volume":"25","author":"Hu","year":"2011","journal-title":"Phytother Res"},{"key":"10.1016\/j.jaad.2019.02.047_bib17","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1271\/bbb.61.1560","article-title":"Beta ray-induced scission of DNA in tritiated water and protection by a green tea percolate and (-)-epigallocatechin gallate","volume":"61","author":"Yoshioka","year":"1997","journal-title":"Biosci Biotechnol Biochem"},{"key":"10.1016\/j.jaad.2019.02.047_bib18","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.mrgentox.2012.04.002","article-title":"Radio- modulatory effects of green tea catechin EGCG on pBR322 plasmid DNA and murine splenocytes against gamma-radiation induced damage","volume":"747","author":"Richi","year":"2012","journal-title":"Mutat Res"},{"key":"10.1016\/j.jaad.2019.02.047_bib19","doi-asserted-by":"crossref","first-page":"10355","DOI":"10.3390\/molecules170910355","article-title":"The dual action of epigallocatechin gallate (EGCG), the main constituent of green tea, against the deleterious effects of visible light and singlet oxygen-generating conditions as seen in yeast cells","volume":"17","author":"Mitrica","year":"2012","journal-title":"Molecules"},{"issue":"1058","key":"10.1016\/j.jaad.2019.02.047_bib20","doi-asserted-by":"crossref","first-page":"20150665","DOI":"10.1259\/bjr.20150665","article-title":"Phase I study of topical epigallocatechin-3-gallate (EGCG) in patients with breast cancer receiving adjuvant radiotherapy","volume":"89","author":"Zhao","year":"2015","journal-title":"Br J Radiol"},{"issue":"30","key":"10.1016\/j.jaad.2019.02.047_bib21","doi-asserted-by":"crossref","first-page":"48607","DOI":"10.18632\/oncotarget.9495","article-title":"Epigallocatechin-3-gallate ameliorates radiation-induced acute skin damage in breast cancer patients undergoing adjuvant radiotherapy","volume":"7","author":"Zhu","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.jaad.2019.02.047_bib22","doi-asserted-by":"crossref","first-page":"163","DOI":"10.4103\/0019-5154.44785","article-title":"Aloe vera: a short review","volume":"53","author":"Surjushe","year":"2008","journal-title":"Indian J Dermatol"},{"issue":"2","key":"10.1016\/j.jaad.2019.02.047_bib23","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0360-3016(96)00320-3","article-title":"Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity","volume":"36","author":"Williams","year":"1996","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"6","key":"10.1016\/j.jaad.2019.02.047_bib24","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1097\/00002820-200212000-00007","article-title":"A phase III study on the efficacy of topical aloe vera gel on irradiated breast tissue","volume":"25","author":"Heggie","year":"2002","journal-title":"Cancer Nurs"},{"key":"10.1016\/j.jaad.2019.02.047_bib25","series-title":"General Radiation Therapy","first-page":"290","article-title":"Carcinoma of the skin","author":"Rode","year":"1966"},{"issue":"2","key":"10.1016\/j.jaad.2019.02.047_bib26","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1055\/s-0028-1099596","article-title":"Study of antimicrobial activity of chamomile oil","volume":"22","author":"Aggag","year":"1972","journal-title":"Planta Med"},{"issue":"3","key":"10.1016\/j.jaad.2019.02.047_bib27","first-page":"395","article-title":"Effect of chamomile cream and almond ointment on acute radiation skin reaction","volume":"30","author":"Maiche","year":"1991","journal-title":"Acta Oncol"},{"issue":"8","key":"10.1016\/j.jaad.2019.02.047_bib28","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1111\/jan.12955","article-title":"Gel of chamomile vs. urea cream to prevent acute radiation dermatitis in patients with head and neck cancer: a randomized controlled trial","volume":"72","author":"Ferreira","year":"2016","journal-title":"J Adv Nurs"},{"issue":"7","key":"10.1016\/j.jaad.2019.02.047_bib29","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/S0305-4179(02)00075-X","article-title":"Benefit-cost analysis of moist exposed burn ointment","volume":"28","author":"Atiyeh","year":"2002","journal-title":"Burns"},{"issue":"3","key":"10.1016\/j.jaad.2019.02.047_bib30","first-page":"e610","article-title":"Randomized, prospective, open-label phase III trial comparing MEBO ointment with Biafine cream for the management of acute dermatitis during radiotherapy for breast cancer","volume":"102","author":"Geara","year":"2018","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.jaad.2019.02.047_bib31","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1093\/jnci\/83.6.396","article-title":"Vitamin C: how it may protect against cancer is unclear","volume":"83","author":"Aubertin","year":"1991","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"10.1016\/j.jaad.2019.02.047_bib32","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0891-5849(88)90056-1","article-title":"Light-stimulated formation of hydrogen peroxide and hydroxyl radical in the presence of uroporphyrin and ascorbate","volume":"5","author":"Bachowski","year":"1988","journal-title":"Free Radic Biol Med"},{"issue":"16","key":"10.1016\/j.jaad.2019.02.047_bib33","doi-asserted-by":"crossref","first-page":"6377","DOI":"10.1073\/pnas.86.16.6377","article-title":"Ascorbate is an outstanding antioxidant in human blood plasma","volume":"86","author":"Frei","year":"1989","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jaad.2019.02.047_bib34","series-title":"Principles and Practice of Radiation Oncology","first-page":"2","article-title":"The discipline of radiation oncology","author":"Halperin","year":"2008"},{"key":"10.1016\/j.jaad.2019.02.047_bib35","series-title":"Martindale: The Extra Pharmacopoeia","year":"1993"},{"issue":"4","key":"10.1016\/j.jaad.2019.02.047_bib36","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/j.ijrobp.2011.09.021","article-title":"Topical hyaluronic acid vs. standard of care for the prevention of radiation dermatitis after adjuvant radiotherapy for breast cancer: single-blind randomized phase III clinical trial","volume":"83","author":"Pinnix","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jaad.2019.02.047_bib37","series-title":"RadiaPlexRx gel protects cultured skin cells from oxidative free radical damage induced by hydrogen peroxide and by irradiation: a pilot study","author":"Gracy","year":"2004"},{"issue":"2","key":"10.1016\/j.jaad.2019.02.047_bib38","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0167-8140(96)01882-8","article-title":"Double-blind, randomized clinical study comparing hyaluronic acid cream to placebo in patients treated with radiotherapy","volume":"42","author":"Liguori","year":"1997","journal-title":"Radiother Oncol"},{"issue":"3","key":"10.1016\/j.jaad.2019.02.047_bib39","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1084\/jem.179.3.831","article-title":"Stimulation of all epithelial elements during skin regeneration by keratinocyte growth factor","volume":"179","author":"Pierce","year":"1994","journal-title":"J Exp Med"},{"issue":"1","key":"10.1016\/j.jaad.2019.02.047_bib40","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/1748-717X-7-162","article-title":"Wound healing after radiation therapy: review of the literature","volume":"7","author":"Haubner","year":"2012","journal-title":"Radiat Oncol"},{"issue":"1","key":"10.1016\/j.jaad.2019.02.047_bib41","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1083\/jcb.146.1.243","article-title":"IP-10 inhibits epidermal growth factor\u2013induced motility by decreasing epidermal growth factor receptor\u2013mediated calpain activity","volume":"146","author":"Shiraha","year":"1999","journal-title":"J Cell Biol"},{"key":"10.1016\/j.jaad.2019.02.047_bib42","doi-asserted-by":"crossref","first-page":"6786","DOI":"10.1073\/pnas.90.14.6786","article-title":"Epidermal growth factor and transforming growth factor alpha specifically induce the activation- and hyperproliferation-associated keratins 6 and 16","volume":"90","author":"Jiang","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jaad.2019.02.047_bib43","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1097\/01.sap.0000198731.12407.0c","article-title":"Recombinant human epidermal growth factor (EGF) to enhance healing for diabetic foot ulcers","volume":"56","author":"Hong","year":"2006","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.jaad.2019.02.047_bib44","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1269\/jrr.10010","article-title":"The preventive effect of recombinant human growth factor (rhEGF) on the recurrence of radiodermatitis","volume":"51","author":"Ryu","year":"2010","journal-title":"J Radiat Res"},{"issue":"3","key":"10.1016\/j.jaad.2019.02.047_bib45","doi-asserted-by":"crossref","first-page":"156","DOI":"10.3857\/roj.2014.32.3.156","article-title":"The safety and efficacy of EGF-based cream for the prevention of radiotherapy-induced skin injury: results from a multicenter observational study","volume":"32","author":"Kang","year":"2014","journal-title":"Rad Oncol J"},{"key":"10.1016\/j.jaad.2019.02.047_bib46","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1001\/archsurg.1991.01410250080013","article-title":"Effects of granulocyte-macrophage colony-stimulating factor in burn patients","volume":"126","author":"Cioffi","year":"1991","journal-title":"Arch Surg"},{"issue":"2","key":"10.1016\/j.jaad.2019.02.047_bib47","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1084\/jem.150.2.231","article-title":"Secretion of plasminogen activator by bone marrow-derived mononuclear phagocytes and its enhancement by colony-stimulating factor","volume":"150","author":"Lin","year":"1978","journal-title":"J Exp Med"},{"issue":"3","key":"10.1016\/j.jaad.2019.02.047_bib48","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.4049\/jimmunol.122.3.1134","article-title":"Stimulation by granulocyte-macrophage colony-stimulating factor of Leishmania tropica killing by macrophages","volume":"122","author":"Handman","year":"1979","journal-title":"J Immunol"},{"issue":"4749","key":"10.1016\/j.jaad.2019.02.047_bib49","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1126\/science.3083507","article-title":"Induction of macrophage tumoricidal activity by granulocyte-macrophage colony-stimulating factor","volume":"232","author":"Grabstein","year":"1986","journal-title":"Science"},{"key":"10.1016\/j.jaad.2019.02.047_bib50","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1046\/j.1365-2133.2001.04115.x","article-title":"Topical granulocyte-macrophage colony-stimulating factor for radiation dermatitis of the vulva","volume":"144","author":"Kouvaris","year":"2001","journal-title":"Br J Dermatol"},{"issue":"10","key":"10.1016\/j.jaad.2019.02.047_bib51","first-page":"5343","article-title":"Topical management of acute radiation dermatitis in breast cancer patients: a systematic review and meta-analysis","volume":"37","author":"Haruna","year":"2017","journal-title":"Anticancer Res"},{"issue":"2","key":"10.1016\/j.jaad.2019.02.047_bib52","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.ijrobp.2018.02.006","article-title":"A randomized trial of mometasone furoate 0.1% to reduce high-grade acute radiation dermatitis in breast cancer patients receiving postmastectomy radiation","volume":"101","author":"Ho","year":"2018","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"10.1016\/j.jaad.2019.02.047_bib53","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1186\/s12885-018-4763-1","article-title":"Topical steroid versus placebo for the prevention of radiation dermatitis in head and neck cancer patients receiving chemoradiotherapy: the study protocol of J-SUPPORT 1602 (TOPICS study), a randomized double-blinded phase 3 trial","volume":"18","author":"Zenda","year":"2018","journal-title":"BMC Cancer"},{"issue":"3","key":"10.1016\/j.jaad.2019.02.047_bib54","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/j.1742-481X.2011.00888.x","article-title":"Potential role of statins on wound healing: review of the literature","volume":"9","author":"Farsaei","year":"2012","journal-title":"Int Wound J"},{"issue":"11","key":"10.1016\/j.jaad.2019.02.047_bib55","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1111\/j.1365-4632.2010.04579.x","article-title":"Statins in dermatology","volume":"49","author":"Jowkar","year":"2010","journal-title":"Int J Dermatol"},{"issue":"2\u20133","key":"10.1016\/j.jaad.2019.02.047_bib56","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1007\/s12026-013-8409-8","article-title":"Statins and autoimmunity","volume":"56","author":"Khattri","year":"2013","journal-title":"Immunol Res"},{"issue":"6","key":"10.1016\/j.jaad.2019.02.047_bib57","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1016\/j.ajpath.2012.08.023","article-title":"Topical simvastatin accelerates wound healing in diabetes by enhancing angiogenesis and lymphangiogenesis","volume":"181","author":"Asai","year":"2012","journal-title":"Am J Pathol"},{"issue":"3","key":"10.1016\/j.jaad.2019.02.047_bib58","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1097\/MAJ.0b013e3181aaf209","article-title":"Topical atorvastatin in the treatment of diabetic wounds","volume":"338","author":"Toker","year":"2009","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.jaad.2019.02.047_bib59","first-page":"1","article-title":"Topical atorvastatin 1% for prevention of skin toxicity in patients receiving radiation therapy for breast cancer: a randomized, double-blind, placebo-controlled trial","volume":"6","author":"Ghasemi","year":"2018","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.jaad.2019.02.047_bib60","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1159\/000211516","article-title":"Biafine applied on human epidermal wounds is chemotactic for macrophages and increases the IL-1\/IL-6 ratio","volume":"10","author":"Coulomb","year":"1997","journal-title":"Skin Pharmacol"},{"issue":"13","key":"10.1016\/j.jaad.2019.02.047_bib61","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1200\/JCO.2005.04.9148","article-title":"Phase III trial of an emulsion containing trolamine for the prevention of radiation dermatitis in patients with advanced squamous cell carcinoma of the head and neck: results of Radiation Therapy Oncology Group Trial 99-13","volume":"24","author":"Elliott","year":"2006","journal-title":"J Clin Oncol"},{"issue":"2","key":"10.1016\/j.jaad.2019.02.047_bib62","first-page":"305","article-title":"Topical Biafine and Lipiderm for the prevention of radiation dermatitis: a randomized prospective trial","volume":"8","author":"Fenig","year":"2001","journal-title":"Oncol Rep"},{"issue":"5","key":"10.1016\/j.jaad.2019.02.047_bib63","doi-asserted-by":"crossref","DOI":"10.1188\/10.ONF.619-626","article-title":"A prospective randomized, placebo-controlled skin care study in women diagnosed with breast cancer undergoing radiation therapy","volume":"37","author":"Gosselin","year":"2010","journal-title":"Oncol Nurs Forum"},{"issue":"1","key":"10.1016\/j.jaad.2019.02.047_bib64","first-page":"185","article-title":"Trolamine emulsion for the prevention of radiation dermatitis in patients with squamous cell carcinoma of the head and neck","volume":"20","author":"Abbas","year":"2012","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.jaad.2019.02.047_bib65","doi-asserted-by":"crossref","first-page":"628","DOI":"10.3923\/ijp.2012.628.637","article-title":"A systematic review of the topical drugs for post hemorrhoidectomy pain","volume":"8","author":"Rahimi","year":"2012","journal-title":"Int J Pharmacol"},{"issue":"2","key":"10.1016\/j.jaad.2019.02.047_bib66","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.radonc.2004.07.032","article-title":"Does aqueous or sucralfate cream affect the severity of erythematous radiation skin reactions? A randomised controlled trial","volume":"73","author":"Wells","year":"2004","journal-title":"Radiother Oncol"},{"issue":"1","key":"10.1016\/j.jaad.2019.02.047_bib67","first-page":"57","article-title":"Radiodermatitis prevention with sucralfate in breast cancer: fundamental and clinical studies","volume":"19","author":"Falkowski","year":"2011","journal-title":"Support Care Cancer"},{"issue":"2","key":"10.1016\/j.jaad.2019.02.047_bib68","first-page":"126","article-title":"Sucralfate gel as a radioprotector against radiation induced dermatitis in a hypo-fractionated schedule: a non-randomized study","volume":"17","author":"Kouloulias","year":"2013","journal-title":"Hippokratia"},{"key":"10.1016\/j.jaad.2019.02.047_bib69","first-page":"472","article-title":"Efficiency of controlled topical delivery of silver sulfadiazine in infected burn wounds","volume":"89","author":"Shanmugasundaram","year":"2008","journal-title":"J Biomed Mater Res A"},{"key":"10.1016\/j.jaad.2019.02.047_bib70","first-page":"e4","article-title":"Comparative evaluation of transdermal formulations of norfloxacin with silver sulfadiazine cream, USP, for burn wound healing property","volume":"5","author":"Malipeddi","year":"2006","journal-title":"J Burns Wounds"},{"key":"10.1016\/j.jaad.2019.02.047_bib71","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1097\/01.bcr.0000176879.27535.09","article-title":"Comparison of silvercoated dressing (Acticoat), chlorhexidine acetate 0.5% (Bactigrass), and silver sulfadiazine 1% (Silverdin) for topical antibacterial effect in Pseudomonas aeruginosa-contaminated, full-skin thickness burn wounds in rats","volume":"26","author":"Ulkur","year":"2005","journal-title":"J Burn Care Rehabil"},{"key":"10.1016\/j.jaad.2019.02.047_bib72","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1046\/j.1365-2133.1997.19432058.x","article-title":"Silver aids healing in the sterile skin wound: experimental studies in the laboratory rat","volume":"137","author":"Lansdown","year":"1997","journal-title":"Br J Dermatol"},{"issue":"8","key":"10.1016\/j.jaad.2019.02.047_bib73","first-page":"1613","article-title":"Topical silver sulfadiazine for the prevention of acute dermatitis during irradiation for breast cancer","volume":"20","author":"Hemati","year":"2012","journal-title":"Support Care Cancer"},{"issue":"3","key":"10.1016\/j.jaad.2019.02.047_bib74","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.ijrobp.2003.11.031","article-title":"Silver leaf nylon dressing to prevent radiation dermatitis in patients undergoing chemotherapy and external beam radiotherapy to the perineum","volume":"59","author":"Vuong","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10.1016\/j.jaad.2019.02.047_bib75","first-page":"18","article-title":"A phase-III study of the efficacy of silver leaf nylon dressing in the prevention of severe skin reactions in the inframammary skin fold of patients receiving adjuvant whole breast radiotherapy","volume":"84","author":"Graham","year":"2007","journal-title":"Radiother Oncol"},{"issue":"2","key":"10.1016\/j.jaad.2019.02.047_bib76","doi-asserted-by":"crossref","first-page":"S171","DOI":"10.1016\/j.ijrobp.2011.06.1679","article-title":"Silver clear nylon dressing is effective in preventing radiation induced dermatitis in patients with gastrointestinal cancer: results from a phase III study","volume":"81","author":"Niazi","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"4","key":"10.1016\/j.jaad.2019.02.047_bib77","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.jmir.2010.08.005","article-title":"Phase III study of silver leaf nylon dressing vs standard care for reduction of inframammary moist desquamation in patients undergoing adjuvant whole breast radiation therapy","volume":"41","author":"Aquino-Parsons","year":"2010","journal-title":"J Med Imag Rad Sci"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S019096221930338X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S019096221930338X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:52:05Z","timestamp":1759272725000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S019096221930338X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":77,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["S019096221930338X"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2019.02.047","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Management of acute radiation dermatitis: A review of the literature and proposal for treatment algorithm","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2019.02.047","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 by the American Academy of Dermatology, Inc.","name":"copyright","label":"Copyright"}]}}