{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:36:27Z","timestamp":1792614987690,"version":"4.5.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100011619","name":"Society for Immunotherapy of Cancer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007812","name":"University of Washington","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007812","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005895","name":"Fred Hutchinson Cancer Research Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005895","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.jaad.2020.07.065","type":"journal-article","created":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T11:14:07Z","timestamp":1595330047000},"page":"330-339","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"title":["Clinical benefit of baseline imaging in Merkel cell carcinoma: Analysis of 584 patients"],"prefix":"10.1016","volume":"84","author":[{"given":"Neha","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nora A.","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Lachance","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher W.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aubriana","family":"McEvoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gensuke","family":"Akaike","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Byrd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanaz","family":"Behnia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shailender","family":"Bhatia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly G.","family":"Paulson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Nghiem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jaad.2020.07.065_bib1","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.jaad.2017.10.028","article-title":"Merkel cell carcinoma: current US incidence and projected increases based on changing demographics","volume":"78","author":"Paulson","year":"2018","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2020.07.065_bib2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ejca.2018.02.003","article-title":"The association between geographic location and incidence of Merkel cell carcinoma in comparison to melanoma: an international assessment","volume":"94","author":"Stang","year":"2018","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.jaad.2020.07.065_bib3","doi-asserted-by":"crossref","first-page":"17077","DOI":"10.1038\/nrdp.2017.77","article-title":"Merkel cell carcinoma","volume":"3","author":"Becker","year":"2017","journal-title":"Nat Rev Dis Primers"},{"issue":"3","key":"10.1016\/j.jaad.2020.07.065_bib4","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.jaad.2007.11.020","article-title":"Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features","volume":"58","author":"Heath","year":"2008","journal-title":"J Am Acad Dermatol"},{"issue":"3","key":"10.1016\/j.jaad.2020.07.065_bib5","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1097\/SLA.0b013e31822c5fc1","article-title":"Five hundred patients with Merkel cell carcinoma evaluated at a single institution","volume":"254","author":"Fields","year":"2011","journal-title":"Ann Surg"},{"issue":"10","key":"10.1016\/j.jaad.2020.07.065_bib6","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1016\/S1470-2045(16)30364-3","article-title":"Avelumab in patients with chemotherapy-refractory metastatic Merkel cell carcinoma: a multicentre, single-group, open-label, phase 2 trial","volume":"17","author":"Kaufman","year":"2016","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.jaad.2020.07.065_bib7","doi-asserted-by":"crossref","first-page":"255","DOI":"10.2217\/fon-2017-0470","article-title":"Nonprogression with avelumab treatment associated with gains in quality of life in metastatic Merkel cell carcinoma","volume":"14","author":"Kaufman","year":"2017","journal-title":"Future Oncol"},{"issue":"26","key":"10.1016\/j.jaad.2020.07.065_bib8","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1056\/NEJMoa1603702","article-title":"PD-1 blockade with pembrolizumab in advanced Merkel cell carcinoma","volume":"374","author":"Nghiem","year":"2016","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1016\/j.jaad.2020.07.065_bib9","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1200\/JCO.18.01896","article-title":"Durable tumor regression and overall survival in patients with advanced merkel cell carcinoma receiving pembrolizumab as first-line therapy","volume":"37","author":"Nghiem","year":"2019","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jaad.2020.07.065_bib10","doi-asserted-by":"crossref","first-page":"2476","DOI":"10.1200\/JCO.20.00201","article-title":"Neoadjuvant nivolumab for patients with resectable Merkel cell carcinoma in the CheckMate 358 Trial","volume":"38","author":"Topalian","year":"2020","journal-title":"J Clin Oncol"},{"issue":"4","key":"10.1016\/j.jaad.2020.07.065_bib11","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1007\/s00262-018-02295-4","article-title":"Early objective response to avelumab treatment is associated with improved overall survival in patients with metastatic Merkel cell carcinoma","volume":"68","author":"D\u2019Angelo","year":"2019","journal-title":"Cancer Immunol Immunother"},{"issue":"4","key":"10.1016\/j.jaad.2020.07.065_bib14","doi-asserted-by":"crossref","first-page":"367","DOI":"10.6004\/jnccn.2019.0018","article-title":"Cutaneous melanoma, version 2.2019, NCCN clinical practice guidelines in oncology","volume":"17","author":"Coit","year":"2019","journal-title":"J Natl Compr Canc Netw"},{"issue":"5","key":"10.1016\/j.jaad.2020.07.065_bib16","doi-asserted-by":"crossref","first-page":"e000382","DOI":"10.1136\/esmoopen-2018-000382","article-title":"Choosing wisely in oncology: necessity and obstacles","volume":"3","author":"Saletti","year":"2018","journal-title":"ESMO Open"},{"issue":"5","key":"10.1016\/j.jaad.2020.07.065_bib17","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1002\/cncr.22868","article-title":"Role of radiologic imaging at the time of initial diagnosis of stage T1b-T3b melanoma","volume":"110","author":"Yancovitz","year":"2007","journal-title":"Cancer"},{"issue":"Suppl 6","key":"10.1016\/j.jaad.2020.07.065_bib18","doi-asserted-by":"crossref","first-page":"vi14","DOI":"10.1093\/annonc\/mdp256","article-title":"Staging of cutaneous melanoma","volume":"20","author":"Mohr","year":"2009","journal-title":"Ann Oncol"},{"issue":"7","key":"10.1016\/j.jaad.2020.07.065_bib20","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1001\/jamadermatol.2013.8116","article-title":"Effect of host, tumor, diagnostic, and treatment variables on outcomes in a large cohort with Merkel cell carcinoma","volume":"150","author":"Asgari","year":"2014","journal-title":"JAMA Dermatol"},{"issue":"3","key":"10.1016\/j.jaad.2020.07.065_bib21","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1097\/MNM.0000000000000039","article-title":"The impact of (18)F-FDG-PET\/CT on Merkel cell carcinoma management: a retrospective study of 66 scans from a single institution","volume":"35","author":"George","year":"2014","journal-title":"Nucl Med Commun"},{"issue":"4","key":"10.1016\/j.jaad.2020.07.065_bib22","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.jaad.2012.08.042","article-title":"Positron emission tomography\/computed tomography imaging in Merkel cell carcinoma: a study of 270 scans in 97 patients at the Dana-Farber\/Brigham and Women\u2019s Cancer Center","volume":"68","author":"Hawryluk","year":"2013","journal-title":"J Am Acad Dermatol"},{"issue":"8","key":"10.1016\/j.jaad.2020.07.065_bib23","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.2967\/jnumed.112.116814","article-title":"18F-FDG PET provides high-impact and powerful prognostic stratification in the staging of Merkel cell carcinoma: a 15-year institutional experience","volume":"54","author":"Siva","year":"2013","journal-title":"J Nucl Med"},{"issue":"3","key":"10.1016\/j.jaad.2020.07.065_bib24","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/1754-9485.12705","article-title":"Prospective analysis of the utility of 18-FDG PET in Merkel cell carcinoma of the skin: a Trans Tasman Radiation Oncology Group Study, TROG 09:03","volume":"62","author":"Poulsen","year":"2018","journal-title":"J Med Imaging Radiat Oncol"},{"issue":"1","key":"10.1016\/j.jaad.2020.07.065_bib25","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.ijrobp.2017.08.029","article-title":"Primary radiation therapy for Merkel cell carcinoma","volume":"100","author":"Tseng","year":"2018","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"3","key":"10.1016\/j.jaad.2020.07.065_bib26","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/jid.2012.388","article-title":"Systemic immune suppression predicts diminished Merkel cell carcinoma-specific survival independent of stage","volume":"133","author":"Paulson","year":"2013","journal-title":"J Invest Dermatol"},{"issue":"6","key":"10.1016\/j.jaad.2020.07.065_bib27","doi-asserted-by":"crossref","first-page":"782","DOI":"10.6004\/jnccn.2018.7049","article-title":"Advances in immunotherapy for metastatic Merkel cell carcinoma: a clinician\u2019s guide","volume":"16","author":"Paulson","year":"2018","journal-title":"J Natl Compr Canc Netw"},{"issue":"3","key":"10.1016\/j.jaad.2020.07.065_bib28","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s00262-017-2099-3","article-title":"Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC","volume":"67","author":"Becker","year":"2018","journal-title":"Cancer Immunol Immunother"},{"issue":"Suppl 3","key":"10.1016\/j.jaad.2020.07.065_bib29","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1245\/s10434-018-6855-1","article-title":"ASO author reflections: the sentinel lymph node in melanoma: now more important than ever","volume":"25","author":"Egger","year":"2018","journal-title":"Ann Surg Oncol"},{"issue":"6","key":"10.1016\/j.jaad.2020.07.065_bib30","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1001\/archderm.142.6.685","article-title":"Sentinel lymph node biopsy for evaluation and treatment of patients with Merkel cell carcinoma: the Dana-Farber experience and meta-analysis of the literature","volume":"142","author":"Gupta","year":"2006","journal-title":"Arch Dermatol"},{"issue":"7","key":"10.1016\/j.jaad.2020.07.065_bib31","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1200\/JOP.2016.014050","article-title":"Importance of sentinel lymph node biopsy in Merkel cell carcinoma","volume":"12","author":"Angeles","year":"2016","journal-title":"J Oncol Pract"},{"issue":"14","key":"10.1016\/j.jaad.2020.07.065_bib32","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1056\/NEJMoa1709684","article-title":"Overall survival with combined nivolumab and ipilimumab in advanced melanoma","volume":"377","author":"Wolchok","year":"2017","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.jaad.2020.07.065_bib33","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1093\/annonc\/mdz011","article-title":"Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001","volume":"30","author":"Hamid","year":"2019","journal-title":"Ann Oncol"},{"key":"10.1016\/j.jaad.2020.07.065_bib34","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1093\/intimm\/dxz012","article-title":"Immunotherapy for skin cancer","volume":"31","author":"Paulson","year":"2019","journal-title":"Int Immunol"},{"issue":"8","key":"10.1016\/j.jaad.2020.07.065_bib35","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1200\/JCO.1995.13.8.2104","article-title":"Role of computed tomography in the staging of patients with local-regional metastases of melanoma","volume":"13","author":"Buzaid","year":"1995","journal-title":"J Clin Oncol"},{"issue":"4","key":"10.1016\/j.jaad.2020.07.065_bib36","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1200\/JCO.1993.11.4.638","article-title":"Role of computed tomography in the staging of primary melanoma","volume":"11","author":"Buzaid","year":"1993","journal-title":"J Clin Oncol"},{"issue":"5","key":"10.1016\/j.jaad.2020.07.065_bib37","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1007\/BF02305552","article-title":"Computed tomography in staging of patients with melanoma metastatic to the regional nodes","volume":"4","author":"Johnson","year":"1997","journal-title":"Ann Surg Oncol"},{"issue":"3","key":"10.1016\/j.jaad.2020.07.065_bib38","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/BF02306618","article-title":"Computed tomography in evaluation of patients with stage III melanoma","volume":"4","author":"Kuvshinoff","year":"1997","journal-title":"Ann Surg Oncol"},{"issue":"11","key":"10.1016\/j.jaad.2020.07.065_bib39","doi-asserted-by":"crossref","first-page":"3564","DOI":"10.1245\/s10434-016-5266-4","article-title":"Analysis of prognostic factors from 9387 Merkel cell carcinoma cases forms the basis for the new 8th edition AJCC staging system","volume":"23","author":"Harms","year":"2016","journal-title":"Ann Surg Oncol"},{"issue":"5","key":"10.1016\/j.jaad.2020.07.065_bib40","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.jaad.2010.02.056","article-title":"Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: analysis of 5823 cases as the basis of the first consensus staging system","volume":"63","author":"Lemos","year":"2010","journal-title":"J Am Acad Dermatol"},{"issue":"1","key":"10.1016\/j.jaad.2020.07.065_bib41","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.jaad.2009.06.021","article-title":"The impact of (18)F-FDG PET-CT scanning for staging and management of Merkel cell carcinoma: results from Westmead Hospital, Sydney, Australia","volume":"62","author":"Concannon","year":"2010","journal-title":"J Am Acad Dermatol"},{"issue":"2","key":"10.1016\/j.jaad.2020.07.065_bib42","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/ajd.12400","volume":"58","author":"Liu","year":"2017","journal-title":"Australas J Dermatol"},{"issue":"3","key":"10.1016\/j.jaad.2020.07.065_bib43","article-title":"Frequency and locations of systemic metastases in Merkel cell carcinoma by imaging","volume":"6","author":"Kouzmina","year":"2017","journal-title":"Acta Radiol Open"},{"issue":"4","key":"10.1016\/j.jaad.2020.07.065_bib44","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1002\/cam4.2781","article-title":"Patterns of distant metastases in 215 Merkel cell carcinoma patients: implications for prognosis and surveillance","volume":"9","author":"Lewis","year":"2020","journal-title":"Cancer Med"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962220322659?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962220322659?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:57:36Z","timestamp":1759273056000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962220322659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":40,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["S0190962220322659"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2020.07.065","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.738386687.793583781","asserted-by":"object"}]},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical benefit of baseline imaging in Merkel cell carcinoma: Analysis of 584 patients","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2020.07.065","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 by the American Academy of Dermatology, Inc.","name":"copyright","label":"Copyright"}]}}