{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:20:30Z","timestamp":1792603230962,"version":"4.5.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T00:00:00Z","timestamp":1628553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","award":["UL1 TR001414"],"award-info":[{"award-number":["UL1 TR001414"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1 TR001414"],"award-info":[{"award-number":["UL1 TR001414"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UL1 TR001414"],"award-info":[{"award-number":["UL1 TR001414"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.jaad.2021.08.007","type":"journal-article","created":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T13:55:45Z","timestamp":1628690145000},"page":"1537-1543","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Vascular characteristics of port wine birthmarks as measured by dynamic optical coherence tomography"],"prefix":"10.1016","volume":"85","author":[{"given":"Joseph N.","family":"Mehrabi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon","family":"Holmes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Abrouk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan V.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyemin","family":"Pomerantz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton M.","family":"Palma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher B.","family":"Zachary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy G.","family":"Geronemus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill S.","family":"Waibel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen M.","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jaad.2021.08.007_bib1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jaad.2011.11.938","article-title":"An overview of clinical and experimental treatment modalities for port wine stains","volume":"67","author":"Chen","year":"2012","journal-title":"J Am Acad Dermatol"},{"issue":"2","key":"10.1016\/j.jaad.2021.08.007_bib2","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1067\/mjd.2001.111353","article-title":"Thickening and nodules in port-wine stains","volume":"44","author":"Klapman","year":"2001","journal-title":"J Am Acad Dermatol"},{"issue":"6","key":"10.1016\/j.jaad.2021.08.007_bib3","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1002\/lsm.20788","article-title":"Port wine stain progression: a potential consequence of delayed and inadequate treatment?","volume":"41","author":"Minkis","year":"2009","journal-title":"Lasers Surg Med"},{"issue":"6","key":"10.1016\/j.jaad.2021.08.007_bib4","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1111\/j.1365-2133.1996.tb07939.x","article-title":"Laser treatment of port wine stains: therapeutic outcome in relation to morphological parameters","volume":"134","author":"Fiskerstrand","year":"1996","journal-title":"Br J Dermatol"},{"issue":"3","key":"10.1016\/j.jaad.2021.08.007_bib5","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/1523-1747.ep12535052","article-title":"The nature and evolution of port wine stains: a computer-assisted study","volume":"74","author":"Barsky","year":"1980","journal-title":"J Invest Dermatol"},{"issue":"5","key":"10.1016\/j.jaad.2021.08.007_bib6","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1111\/1523-1747.ep12365566","article-title":"Photothermally induced vessel-wall necrosis after pulsed dye laser treatment: lack of response in port-wine stains with small sized or deeply located vessels","volume":"107","author":"Fiskerstrand","year":"1996","journal-title":"J Invest Dermatol"},{"issue":"4596","key":"10.1016\/j.jaad.2021.08.007_bib7","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1126\/science.6836297","article-title":"Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation","volume":"220","author":"Anderson","year":"1983","journal-title":"Science"},{"issue":"10","key":"10.1016\/j.jaad.2021.08.007_bib8","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1002\/lsm.23134","article-title":"Characterization of laser-resistant port wine stain blood vessels using in\u00a0vivo reflectance confocal microscopy","volume":"51","author":"Fu","year":"2019","journal-title":"Lasers Surg Med"},{"issue":"7","key":"10.1016\/j.jaad.2021.08.007_bib9","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1002\/lsm.22816","article-title":"Angiographic optical coherence tomography imaging of hemangiomas and port wine birthmarks","volume":"50","author":"Waibel","year":"2018","journal-title":"Lasers Surg Med"},{"issue":"2","key":"10.1016\/j.jaad.2021.08.007_bib10","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/srt.12253","article-title":"Characterization of skin port-wine stain and hemangioma vascular lesions using Doppler OCT","volume":"22","author":"Latrive","year":"2016","journal-title":"Skin Res Technol"},{"issue":"10","key":"10.1016\/j.jaad.2021.08.007_bib11","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1002\/lsm.22194","article-title":"In\u00a0vivo, high-resolution, three-dimensional imaging of port wine stain microvasculature in human skin","volume":"45","author":"Liu","year":"2013","journal-title":"Lasers Surg Med"},{"issue":"6","key":"10.1016\/j.jaad.2021.08.007_bib12","first-page":"741","article-title":"Imaging blood flow in human port-wine stain in situ and in real time using optical Doppler tomography","volume":"137","author":"Nelson","year":"2001","journal-title":"Arch Dermatol"},{"issue":"5","key":"10.1016\/j.jaad.2021.08.007_bib13","first-page":"603","article-title":"Optical coherence tomography in dermatology","volume":"150","author":"Olsen","year":"2015","journal-title":"G Ital Dermatol Venereol"},{"issue":"1","key":"10.1016\/j.jaad.2021.08.007_bib14","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/srt.12399","article-title":"In\u00a0vivo measurements of blood vessels' distribution in non-melanoma skin cancer by dynamic optical coherence tomography: a new quantitative measure?","volume":"24","author":"Sigsgaard","year":"2018","journal-title":"Skin Res Technol"},{"issue":"5","key":"10.1016\/j.jaad.2021.08.007_bib15","doi-asserted-by":"crossref","first-page":"050901","DOI":"10.1117\/1.JBO.18.5.050901","article-title":"Review of speckle and phase variance optical coherence tomography to visualize microvascular networks","volume":"18","author":"Mahmud","year":"2013","journal-title":"J Biomed Opt"},{"issue":"6","key":"10.1016\/j.jaad.2021.08.007_bib16","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1111\/jdv.13596","article-title":"In\u00a0vivo, micro-morphological vascular changes induced by topical brimonidine studied by dynamic optical coherence tomography","volume":"30","author":"Themstrup","year":"2016","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"5","key":"10.1016\/j.jaad.2021.08.007_bib17","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1002\/lsm.10102","article-title":"Comparing the effectiveness of 585-nm vs 595-nm wavelength pulsed dye laser treatment of port wine stains in conjunction with cryogen spray cooling","volume":"31","author":"Chang","year":"2002","journal-title":"Lasers Surg Med"},{"issue":"2","key":"10.1016\/j.jaad.2021.08.007_bib18","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1002\/lsm.20003","article-title":"Prospective study of port wine stain treatment with dye laser: comparison of two wavelengths (585 nm vs. 595 nm) and two pulse durations (0.5 milliseconds vs. 20 milliseconds)","volume":"34","author":"Greve","year":"2004","journal-title":"Lasers Surg Med"},{"issue":"7","key":"10.1016\/j.jaad.2021.08.007_bib19","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1001\/archderm.136.7.942","article-title":"High-fluence modified pulsed dye laser photocoagulation with dynamic cooling of port-wine stains in infancy","volume":"136","author":"Geronemus","year":"2000","journal-title":"Arch Dermatol"},{"issue":"3","key":"10.1016\/j.jaad.2021.08.007_bib20","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1111\/j.1365-2133.2005.06707.x","article-title":"A comparative study of a 595-nm with a 585-nm pulsed dye laser in refractory port wine stains","volume":"153","author":"Yung","year":"2005","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2021.08.007_bib21","series-title":"Optical-Thermal Response of Laser-Irradiated Tissue","year":"2011"},{"issue":"5","key":"10.1016\/j.jaad.2021.08.007_bib22","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1002\/lsm.10234","article-title":"Treatment of resistant port wine stains with the V Beam pulsed dye laser","volume":"33","author":"Laube","year":"2003","journal-title":"Lasers Surg Med"},{"issue":"9","key":"10.1016\/j.jaad.2021.08.007_bib23","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1111\/jdv.13177","article-title":"Guidelines of care for vascular lasers and intense pulse light sources from the European Society for Laser Dermatology","volume":"29","author":"Adami\u010d","year":"2015","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"1","key":"10.1016\/j.jaad.2021.08.007_bib24","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/lsm.22600","article-title":"Reflectance confocal microscopy of skin in\u00a0vivo: from bench to bedside","volume":"49","author":"Rajadhyaksha","year":"2017","journal-title":"Lasers Surg Med"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962221022957?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962221022957?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:59:40Z","timestamp":1759273180000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962221022957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["S0190962221022957"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2021.08.007","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vascular characteristics of port wine birthmarks as measured by dynamic optical coherence tomography","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2021.08.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 by the American Academy of Dermatology, Inc. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}