{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:03:27Z","timestamp":1790096607321,"version":"4.0.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.jaad.2023.07.008","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T02:48:48Z","timestamp":1689302928000},"page":"959-966","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Histologic margin status is a predictor of relapse in lentigo maligna melanoma"],"prefix":"10.1016","volume":"89","author":[{"given":"Mai P.","family":"Hoang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawel","family":"Karpinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Z\u00fa\u00f1iga-Castillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth K.","family":"Foreman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin S.","family":"Emerick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur J.","family":"Sober","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jaad.2023.07.008_bib1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.jaad.2015.04.014","article-title":"Melanoma in situ: part I. Epidemiology, screening, and clinical features","volume":"73","author":"Higgins","year":"2015","journal-title":"J Am Acad Dermatol"},{"issue":"4","key":"10.1016\/j.jaad.2023.07.008_bib2","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1111\/j.0022-202X.2005.23852.x","article-title":"Increasing incidence of lentigo maligna melanoma subtypes: northern California and national trends 1990-2000","volume":"125","author":"Swetter","year":"2005","journal-title":"J Invest Dermatol"},{"issue":"8","key":"10.1016\/j.jaad.2023.07.008_bib4","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1054\/bjps.2002.3967","article-title":"A follow-up study to investigate the efficacy of initial treatment of lentigo maligna with surgical excision","volume":"55","author":"Osborne","year":"2002","journal-title":"Br J Plast Surg"},{"issue":"3","key":"10.1016\/j.jaad.2023.07.008_bib5","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1111\/bjd.14325","article-title":"Recurrence rate of lentigo maligna after micrographically controlled staged surgical excision","volume":"174","author":"De Vries","year":"2016","journal-title":"Br J Dermatol"},{"issue":"1","key":"10.1016\/j.jaad.2023.07.008_bib6","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.jaad.2018.08.055","article-title":"Guidelines of care for the management of primary cutaneous melanoma","volume":"80","author":"Swetter","year":"2019","journal-title":"J Am Acad Dermatol"},{"issue":"1","key":"10.1016\/j.jaad.2023.07.008_bib7","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.jaad.2019.01.051","article-title":"Comparison of surgical margins for lentigo maligna versus melanoma in situ","volume":"81","author":"Kunishige","year":"2019","journal-title":"J Am Acad Dermatol"},{"issue":"5","key":"10.1016\/j.jaad.2023.07.008_bib8","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1067\/mjd.2002.124085","article-title":"Histologic evaluation of lentigo maligna with permanent sections: implications regarding current guidelines","volume":"47","author":"Agarwal-Antal","year":"2002","journal-title":"J Am Acad Dermatol"},{"issue":"1","key":"10.1016\/j.jaad.2023.07.008_bib9","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.jaad.2004.08.038","article-title":"Cutaneous head and neck melanoma treated with Mohs micrographic surgery","volume":"52","author":"Bricca","year":"2005","journal-title":"J Am Acad Dermatol"},{"issue":"1","key":"10.1016\/j.jaad.2023.07.008_bib10","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.jaad.2007.09.023","article-title":"Staged excision for lentigo maligna and lentigo maligna melanoma: a retrospective analysis of 117 cases","volume":"58","author":"Hazan","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jaad.2023.07.008_bib11","series-title":"AJCC Cancer Staging Manual","article-title":"Melanoma of the skin","author":"Gershenwald","year":"2017"},{"issue":"3","key":"10.1016\/j.jaad.2023.07.008_bib12","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/sj.bjc.6601119","article-title":"Survival analysis part II: multivariate data analysis\u2013an introduction to concepts and methods","volume":"89","author":"Bradburn","year":"2003","journal-title":"Br J Cancer"},{"key":"10.1016\/j.jaad.2023.07.008_bib13","series-title":"Modeling Survival Data: Extending the Cox Model","author":"Therneau","year":"2000"},{"key":"10.1016\/j.jaad.2023.07.008_bib14","series-title":"R: a language and environment for statistical computing","year":"2023"},{"issue":"5","key":"10.1016\/j.jaad.2023.07.008_bib15","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.ad.2023.02.019","article-title":"Update on lentigo maligna: diagnostic signs and treatment","volume":"114","author":"Requena","year":"2023","journal-title":"Actas Dermosifiliogr"},{"issue":"4","key":"10.1016\/j.jaad.2023.07.008_bib16","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.annder.2022.03.008","article-title":"Clinical features associated with the invasive component in lentigo maligna of the head and neck: a retrospective study of 175 cases","volume":"149","author":"G\u00e9rard","year":"2022","journal-title":"Ann Dermatol Venereol"},{"issue":"6","key":"10.1016\/j.jaad.2023.07.008_bib17","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1111\/jdv.17135","article-title":"Lentiginous melanoma (lentigo maligna and lentigo maligna melanoma) in Australia: clinicopathological characteristics, management and recurrence rates after 10-year follow-up at a tertiary center","volume":"35","author":"Collgros","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"3","key":"10.1016\/j.jaad.2023.07.008_bib18","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.jaad.2021.04.090","article-title":"Systematic review and meta-analysis of local recurrence rates of head and neck cutaneous melanomas after wide local excision, Mohs micrographic surgery, or staged excision","volume":"85","author":"Bittar","year":"2021","journal-title":"J Am Acad Dermatol"},{"issue":"5","key":"10.1016\/j.jaad.2023.07.008_bib19","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.ejso.2020.09.028","article-title":"Clinical outcomes following surgical treatment of lentigo maligna of the head and neck","volume":"47","author":"Crouch","year":"2021","journal-title":"Eur J Surg Oncol"},{"issue":"5","key":"10.1016\/j.jaad.2023.07.008_bib20","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1158\/1078-0432.CCR-09-2721","article-title":"Melanoma microRNA signature predicts post-recurrence survival","volume":"16","author":"Segura","year":"2010","journal-title":"Clin Cancer Res"},{"issue":"3","key":"10.1016\/j.jaad.2023.07.008_bib21","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1111\/pcmr.12343","article-title":"MicroRNA and mRNA expression profiling in metastatic melanoma reveal associations with BRAF mutation and patient prognosis","volume":"28","author":"Tembe","year":"2015","journal-title":"Pigment Cell Melanoma Res"},{"issue":"1","key":"10.1016\/j.jaad.2023.07.008_bib22","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/s41698-022-00321-4","article-title":"Prediction of early-stage melanoma recurrence using clinical and histopathologic features","volume":"6","author":"Wan","year":"2022","journal-title":"NPJ Precis Oncol"},{"issue":"6","key":"10.1016\/j.jaad.2023.07.008_bib23","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1002\/1097-0142(19850315)55:6<1398::AID-CNCR2820550639>3.0.CO;2-A","article-title":"The influence of surgical margins and prognostic factors predicting the risk of local recurrence in 3445 patients with primary cutaneous melanoma","volume":"55","author":"Urist","year":"1985","journal-title":"Cancer"},{"issue":"4","key":"10.1016\/j.jaad.2023.07.008_bib24","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.cps.2021.06.007","article-title":"Lentigo maligna","volume":"48","author":"Franke","year":"2021","journal-title":"Clin Plast Surg"},{"issue":"3","key":"10.1016\/j.jaad.2023.07.008_bib25","doi-asserted-by":"crossref","first-page":"346","DOI":"10.36849\/JDD.5660","article-title":"Topical Imiquimod for lentigo maligna: survival analysis of 103 cases with 17 years of follow-up","volume":"20","author":"Chambers","year":"2021","journal-title":"J Drugs Dermatol"},{"issue":"8","key":"10.1016\/j.jaad.2023.07.008_bib26","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1001\/jamadermatol.2018.0530","article-title":"Rate of recurrence of lentigo maligna treated with off-label neoadjuvant topical imiquimod, 5%, cream prior to conservatively staged excision","volume":"154","author":"Donigan","year":"2018","journal-title":"JAMA Dermatol"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S019096222301349X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S019096222301349X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T23:28:15Z","timestamp":1759274895000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S019096222301349X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S019096222301349X"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2023.07.008","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Histologic margin status is a predictor of relapse in lentigo maligna melanoma","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2023.07.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 by the American Academy of Dermatology, Inc.","name":"copyright","label":"Copyright"}]}}