{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:20:32Z","timestamp":1792603232824,"version":"4.5.0"},"reference-count":13,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaad.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Academy of Dermatology"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.jaad.2025.12.034","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T16:18:05Z","timestamp":1765556285000},"page":"1447-1453","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Surgical excision versus topical 5% 5-fluorouracil and photodynamic therapy in the treatment of Bowen's disease: Long-term results of a multicenter randomized controlled trial"],"prefix":"10.1016","volume":"94","author":[{"given":"Myrthe M.G.","family":"Moermans","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shima","family":"Ahmady","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patty J.","family":"Nelemans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aim\u00e9e H.M.M.","family":"Arits","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janneke P.H.M.","family":"Kessels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han P.A.","family":"van Pelt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole W.J.","family":"Kelleners-Smeets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klara","family":"Mosterd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.jaad.2025.12.034_bib1","article-title":"Interventions for cutaneous Bowen's disease","volume":"2013","author":"Bath-Hextall","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"issue":"Suppl 5","key":"10.1016\/j.jaad.2025.12.034_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1468-3083.2011.04296.x","article-title":"Guidelines for the diagnosis and treatment of cutaneous squamous cell carcinoma and precursor lesions","volume":"25","author":"Bonerandi","year":"2011","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"2","key":"10.1016\/j.jaad.2025.12.034_bib3","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/bjd.12766","article-title":"British Association of Dermatologists' guidelines for the management of squamous cell carcinoma in situ (Bowen's disease) 2014","volume":"170","author":"Morton","year":"2014","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jaad.2025.12.034_bib4","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1001\/archderm.1961.01580160087015","article-title":"An association between Bowen's disease and internal cancer","volume":"84","author":"Peterka","year":"1961","journal-title":"Arch Dermatol"},{"issue":"10","key":"10.1016\/j.jaad.2025.12.034_bib5","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1001\/archderm.1986.01660220042010","article-title":"Carcinoma arising in Bowen's disease","volume":"122","author":"Kao","year":"1986","journal-title":"Arch Dermatol"},{"issue":"1","key":"10.1016\/j.jaad.2025.12.034_bib6","doi-asserted-by":"crossref","first-page":"64","DOI":"10.2340\/00015555-2175","article-title":"A retrospective study of treatment of squamous cell carcinoma in situ","volume":"96","author":"\u00d6vermark","year":"2016","journal-title":"Acta Derm Venereol"},{"issue":"1","key":"10.1016\/j.jaad.2025.12.034_bib7","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jaad.2023.08.076","article-title":"Surgical excision versus topical 5% 5-fluorouracil and photodynamic therapy in treatment of Bowen's disease: a multicenter randomized controlled trial","volume":"90","author":"Ahmady","year":"2024","journal-title":"J Am Acad Dermatol"},{"issue":"2","key":"10.1016\/j.jaad.2025.12.034_bib8","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1093\/bjd\/ljac042","article-title":"British Association of Dermatologists guidelines for the management of people with cutaneous squamous cell carcinoma in situ (Bowen disease) 2022","volume":"188","author":"Sharma","year":"2023","journal-title":"Br J Dermatol"},{"issue":"3","key":"10.1016\/j.jaad.2025.12.034_bib9","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1111\/jdv.20267","article-title":"Efficacy of interventions for cutaneous squamous cell carcinoma in situ (Bowen's disease): a systematic review and meta-analysis of proportions","volume":"39","author":"Petzold","year":"2025","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"1","key":"10.1016\/j.jaad.2025.12.034_bib10","doi-asserted-by":"crossref","first-page":"114","DOI":"10.2340\/00015555-2777","article-title":"Bowen's disease: long-term results of treatment with 5-fluorouracil cream, photodynamic therapy or surgical excision","volume":"98","author":"Jansen","year":"2018","journal-title":"Acta Derm Venereol"},{"issue":"9","key":"10.1016\/j.jaad.2025.12.034_bib11","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1001\/jamadermatol.2020.1988","article-title":"Assessment of cutaneous squamous cell carcinoma (cSCC) in situ incidence and the risk of developing invasive cSCC in patients with prior cSCC in situ vs the general population in the Netherlands, 1989-2017","volume":"156","author":"Tokez","year":"2020","journal-title":"JAMA Dermatol"},{"issue":"11","key":"10.1016\/j.jaad.2025.12.034_bib12","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1097\/DSS.0000000000001980","article-title":"Trends in the incidence of Bowen disease based on a single-center study in the Netherlands","volume":"45","author":"Jansen","year":"2019","journal-title":"Dermatol Surg"},{"issue":"5-6","key":"10.1016\/j.jaad.2025.12.034_bib13","first-page":"489","article-title":"Cost-effectiveness of photodynamic therapy and 5-fluorouracil cream versus surgical excision in treatment of Bowen\u2019s disease: a trial-based economic evaluation","volume":"241","author":"Ahmady","year":"2025","journal-title":"Dermatology"}],"container-title":["Journal of the American Academy of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962225033808?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0190962225033808?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T06:08:13Z","timestamp":1776406093000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0190962225033808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S0190962225033808"],"URL":"https:\/\/doi.org\/10.1016\/j.jaad.2025.12.034","relation":{},"ISSN":["0190-9622"],"issn-type":[{"value":"0190-9622","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Surgical excision versus topical 5% 5-fluorouracil and photodynamic therapy in the treatment of Bowen's disease: Long-term results of a multicenter randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Academy of Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaad.2025.12.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc. on behalf of the American Academy of Dermatology, Inc.","name":"copyright","label":"Copyright"}]}}