{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T21:13:56Z","timestamp":1772745236036,"version":"3.50.1"},"reference-count":14,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jaapos.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of American Association for Pediatric Ophthalmology and Strabismus"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.jaapos.2020.11.008","type":"journal-article","created":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T11:31:16Z","timestamp":1613561476000},"page":"109-112.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Isolated bilateral congenital lacrimal gland agenesis\u2014a case series"],"prefix":"10.1016","volume":"25","author":[{"given":"Nebras","family":"Alghazawi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milad","family":"Modabber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rami","family":"Darwich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avi","family":"Saskin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Russell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Saint-Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayesha","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaapos.2020.11.008_bib1","first-page":"7542929","article-title":"Review: the lacrimal gland and its role in dry eye","volume":"2016","author":"Conrady","year":"2016","journal-title":"J\u00a0Ophthalmol"},{"key":"10.1016\/j.jaapos.2020.11.008_bib2","first-page":"e35","article-title":"Isolated bilateral lacrimal gland agenesis","volume":"53","author":"Al-Ryalat","year":"2016","journal-title":"J\u00a0Pediatr Ophthalmol Strabismus"},{"key":"10.1016\/j.jaapos.2020.11.008_bib3","first-page":"72","article-title":"Bilateral congenital agenesis of lacrimal glands in a Tunisian family","volume":"94","author":"Chebil","year":"2016","journal-title":"Tunis Med"},{"key":"10.1016\/j.jaapos.2020.11.008_bib4","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/ICO.0b013e3181814ca9","article-title":"Isolated unilateral congenital lacrimal gland agenesis presenting as filamentary keratopathy in a child","volume":"28","author":"Demetriades","year":"2009","journal-title":"Cornea"},{"key":"10.1016\/j.jaapos.2020.11.008_bib5","first-page":"e52","article-title":"Unilateral congenital lacrimal gland agenesis with contralateral lacrimal gland hypoplasia","volume":"52","author":"Talsania","year":"2015","journal-title":"J\u00a0Pediatr Ophthalmol Strabismus"},{"key":"10.1016\/j.jaapos.2020.11.008_bib6","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1001\/archopht.118.2.246","article-title":"Tear production after unilateral removal of the main lacrimal gland in squirrel monkeys","volume":"118","author":"Maitchouk","year":"2000","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jaapos.2020.11.008_bib7","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.ajhg.2016.04.003","article-title":"Consideration of cosegregation in the pathogenicity classification of genomic variants","volume":"98","author":"Jarvik","year":"2016","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jaapos.2020.11.008_bib8","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.sjopt.2017.04.008","article-title":"Isolated bilateral congenital lacrimal gland agenesis\u2014report of two cases","volume":"31","author":"Alwohaib","year":"2017","journal-title":"Saudi J Ophthalmol"},{"key":"10.1016\/j.jaapos.2020.11.008_bib9","doi-asserted-by":"crossref","first-page":"88","DOI":"10.5966\/sctm.2016-0191","article-title":"Lacrimal gland repair using progenitor cells","volume":"6","author":"Gromova","year":"2017","journal-title":"Stem Cells Transl Med"},{"key":"10.1016\/j.jaapos.2020.11.008_bib10","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/978-1-4939-6949-4_11","article-title":"Generation of a bioengineered lacrimal gland by using the organ germ method","volume":"1597","author":"Hirayama","year":"2017","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.jaapos.2020.11.008_bib11","doi-asserted-by":"crossref","first-page":"522","DOI":"10.4103\/0301-4738.86333","article-title":"Isolated form of congenital bilateral lacrimal gland agenesis","volume":"59","author":"Sahinoglu","year":"2011","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.jaapos.2020.11.008_bib12","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0008-4182(05)80124-3","article-title":"Alacrima presenting in the third decade","volume":"40","author":"Al-Muammar","year":"2005","journal-title":"Can J Ophthalmol"},{"key":"10.1016\/j.jaapos.2020.11.008_bib13","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/0002-9394(86)90416-2","article-title":"Congenital absence of the lacrimal gland","volume":"102","author":"Keith","year":"1986","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jaapos.2020.11.008_bib14","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1001\/archopht.1968.03850040047013","article-title":"Congenital alacrima","volume":"79","author":"Smith","year":"1968","journal-title":"Arch Ophthalmol"}],"container-title":["Journal of American Association for Pediatric Ophthalmology and Strabismus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109185312100032X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109185312100032X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T20:24:52Z","timestamp":1761078292000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S109185312100032X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["S109185312100032X"],"URL":"https:\/\/doi.org\/10.1016\/j.jaapos.2020.11.008","relation":{},"ISSN":["1091-8531"],"issn-type":[{"value":"1091-8531","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Isolated bilateral congenital lacrimal gland agenesis\u2014a case series","name":"articletitle","label":"Article Title"},{"value":"Journal of American Association for Pediatric Ophthalmology and Strabismus","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaapos.2020.11.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}