{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T00:25:50Z","timestamp":1793924750329,"version":"4.8.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T00:00:00Z","timestamp":1740614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["24CDA1257995"],"award-info":[{"award-number":["24CDA1257995"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["1R01HL154744"],"award-info":[{"award-number":["1R01HL154744"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["1R01HL129185"],"award-info":[{"award-number":["1R01HL129185"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["1R01HL129157"],"award-info":[{"award-number":["1R01HL129157"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["1R01HL127015"],"award-info":[{"award-number":["1R01HL127015"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Advances"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.jacadv.2025.101684","type":"journal-article","created":{"date-parts":[[2025,3,23]],"date-time":"2025-03-23T14:12:52Z","timestamp":1742739172000},"page":"101684","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Radiomic Cardiac MRI Signatures for\u00a0Predicting Ventricular Arrhythmias in\u00a0Patients With Nonischemic Dilated\u00a0Cardiomyopathy"],"prefix":"10.1016","volume":"4","author":[{"given":"Amine","family":"Amyar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danah","family":"Al-Deiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2490-5106","authenticated-orcid":false,"given":"Jakub","family":"Sroubek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Kiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahime","family":"Ghanbari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiro","family":"Nakamori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel B.","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren J.","family":"Manning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2191-4111","authenticated-orcid":false,"given":"Deborah","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Nezafat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacadv.2025.101684_bib1","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1161\/CIRCULATIONAHA.113.007149","article-title":"Risk stratification for sudden cardiac death: a plan for the future","volume":"129","author":"Goldberger","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.jacadv.2025.101684_bib2","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1016\/j.jacc.2017.10.053","volume":"72","author":"Al-Khatib","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacadv.2025.101684_bib3","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1161\/CIRCULATIONAHA.116.027134","article-title":"Personalizing risk stratification for sudden death in dilated cardiomyopathy: the past, present, and future","volume":"136","author":"Halliday","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.jacadv.2025.101684_bib4","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1161\/CIRCULATIONAHA.116.026056","article-title":"Implantable cardioverter-defibrillator for nonischemic cardiomyopathy: an updated meta-analysis","volume":"135","author":"Golwala","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.jacadv.2025.101684_bib5","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.jacep.2017.02.006","article-title":"Efficacy of implantable cardioverter-defibrillator therapy in patients with nonischemic cardiomyopathy: a systematic review and meta-analysis of randomized controlled trials","volume":"3","author":"Anantha Narayanan","year":"2017","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.jacadv.2025.101684_bib6","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1056\/NEJMoa1608029","article-title":"Defibrillator implantation in patients with nonischemic systolic heart failure","volume":"375","author":"K\u00f8ber","year":"2016","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacadv.2025.101684_bib7","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.223008","article-title":"Cardiac MRI: state of the art","volume":"307","author":"Rajiah","year":"2023","journal-title":"Radiology"},{"key":"10.1016\/j.jacadv.2025.101684_bib8","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1161\/01.CIR.100.19.1992","article-title":"Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function","volume":"100","author":"Kim","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.jacadv.2025.101684_bib9","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.222239","article-title":"AI cardiac MRI scar analysis aids prediction of major arrhythmic events in the multicenter DERIVATE registry","volume":"307","author":"Ghanbari","year":"2023","journal-title":"Radiology"},{"key":"10.1016\/j.jacadv.2025.101684_bib10","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1001\/jama.2013.1363","article-title":"Association of fibrosis with mortality and sudden cardiac death in patients with nonischemic dilated cardiomyopathy","volume":"309","author":"Gulati","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.jacadv.2025.101684_bib11","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1161\/CIRCIMAGING.113.001144","article-title":"Late gadolinium enhancement on cardiac magnetic resonance predicts adverse cardiovascular outcomes in nonischemic cardiomyopathy: a systematic review and meta-analysis","volume":"7","author":"Kuruvilla","year":"2014","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.jacadv.2025.101684_bib12","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/j.jcmg.2013.05.013","article-title":"CMR quantification of myocardial scar provides additive prognostic information in nonischemic cardiomyopathy","volume":"6","author":"Neilan","year":"2013","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.jacadv.2025.101684_bib13","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1161\/CIRCEP.113.000537","article-title":"Contrast-enhanced MRI\u2013derived scar patterns and associated ventricular tachycardias in nonischemic cardiomyopathy: implications for the ablation strategy","volume":"6","author":"Piers","year":"2013","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.jacadv.2025.101684_bib14","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1016\/j.jcmg.2018.03.006","article-title":"The prognostic value of late gadolinium-enhanced cardiac magnetic resonance imaging in nonischemic dilated cardiomyopathy: a review and meta-analysis","volume":"11","author":"Becker","year":"2018","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.jacadv.2025.101684_bib15","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2021.766287","article-title":"Radiomics analysis derived from LGE-MRI predict sudden cardiac death in participants with hypertrophic cardiomyopathy","volume":"8","author":"Wang","year":"2021","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.jacadv.2025.101684_bib16","first-page":"16","article-title":"Radiomics of late gadolinium enhancement reveals prognostic value of myocardial scar heterogeneity in hypertrophic cardiomyopathy","volume":"17","author":"Fahmy","year":"2024","journal-title":"Cardiovasc Imaging"},{"key":"10.1016\/j.jacadv.2025.101684_bib17","series-title":"Clinical Cardiac Electrophysiology: Techniques and Interpretations","author":"Josephson","year":"2008"},{"key":"10.1016\/j.jacadv.2025.101684_bib18","doi-asserted-by":"crossref","first-page":"e104","DOI":"10.1158\/0008-5472.CAN-17-0339","article-title":"Computational radiomics system to decode the radiographic phenotype","volume":"77","author":"Van Griethuysen","year":"2017","journal-title":"Cancer Res"},{"key":"10.1016\/j.jacadv.2025.101684_bib19","doi-asserted-by":"crossref","first-page":"R150","DOI":"10.1088\/0031-9155\/61\/13\/R150","article-title":"Applications and limitations of radiomics","volume":"61","author":"Yip","year":"2016","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.jacadv.2025.101684_bib20","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1023\/A:1023949509487","article-title":"Consensus clustering: a resampling-based method for class discovery and visualization of gene expression microarray data","volume":"52","author":"Monti","year":"2003","journal-title":"Mach Learn"},{"key":"10.1016\/j.jacadv.2025.101684_bib21","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1093\/bioinformatics\/btq170","article-title":"ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking","volume":"26","author":"Wilkerson","year":"2010","journal-title":"Bioinform"},{"key":"10.1016\/j.jacadv.2025.101684_bib22","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1161\/CIRCHEARTFAILURE.115.002414","article-title":"Clinical risk stratification for primary prevention implantable cardioverter defibrillators","volume":"8","author":"Lee","year":"2015","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jacadv.2025.101684_bib23","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1136\/hrt.2005.085761","article-title":"Management of patients with non-ischaemic cardiomyopathy","volume":"93","author":"Wu","year":"2007","journal-title":"Heart"},{"key":"10.1016\/j.jacadv.2025.101684_bib24","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.jacc.2023.05.064","article-title":"Risk of arrhythmic death in patients with nonischemic cardiomyopathy: JACC Review Topic of the Week","volume":"82","author":"Chrispin","year":"2023","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacadv.2025.101684_bib25","first-page":"1976","article-title":"MRI assessment of myocardial deformation for risk stratification of major arrhythmic events in patients with non-ischemic cardiomyopathy eligible for primary prevention implantable cardioverter defibrillators","volume":"60","author":"Ghanbari","year":"2024","journal-title":"J\u00a0Magn Reson Imaging"},{"key":"10.1016\/j.jacadv.2025.101684_bib26","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1161\/01.CIR.0000078641.19365.4C","article-title":"Differentiation of heart failure related to dilated cardiomyopathy and coronary artery disease using gadolinium-enhanced cardiovascular magnetic resonance","volume":"108","author":"McCrohon","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jacadv.2025.101684_bib27","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1093\/eurheartj\/ehi258","article-title":"Delayed enhancement cardiovascular magnetic resonance assessment of non-ischaemic cardiomyopathies","volume":"26","author":"Mahrholdt","year":"2005","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacadv.2025.101684_bib28","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1161\/CIRCULATIONAHA.123.067107","article-title":"Cardiovascular magnetic resonance radiomics to identify components of the extracellular matrix in dilated cardiomyopathy","volume":"150","author":"Nakamori","year":"2024","journal-title":"Circulation"},{"key":"10.1016\/j.jacadv.2025.101684_bib29","doi-asserted-by":"crossref","DOI":"10.1038\/srep11044","article-title":"Radiomic feature clusters and prognostic signatures specific for lung and head & neck cancer","volume":"5","author":"Parmar","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.jacadv.2025.101684_bib30","doi-asserted-by":"crossref","DOI":"10.1148\/ryct.2020190216","article-title":"Reproducibility of segmentation-based myocardial radiomic features with cardiac MRI","volume":"2","author":"Jang","year":"2020","journal-title":"Radiol Cardiothorac Imaging"},{"key":"10.1016\/j.jacadv.2025.101684_bib31","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1148\/radiol.2021202553","article-title":"The biological meaning of radiomic features","volume":"298","author":"Tomaszewski","year":"2021","journal-title":"Radiology"},{"key":"10.1016\/j.jacadv.2025.101684_bib32","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1161\/CIRCULATIONAHA.113.002518","article-title":"The prevalence and prognostic significance of right ventricular systolic dysfunction in nonischemic dilated cardiomyopathy","volume":"128","author":"Gulati","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.jacadv.2025.101684_bib33","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.jacc.2018.12.076","article-title":"Anatomy, function, and dysfunction of the right ventricle: JACC state-of-the-art review","volume":"73","author":"Sanz","year":"2019","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacadv.2025.101684_bib34","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.116.004067","article-title":"Right ventricular ejection fraction is incremental to left ventricular ejection fraction for the prediction of future arrhythmic events in patients with systolic dysfunction","volume":"10","author":"Mikami","year":"2017","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.jacadv.2025.101684_bib35","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.118.007022","article-title":"Right ventricular dysfunction and the effect of defibrillator implantation in patients with nonischemic systolic heart failure","volume":"12","author":"Elming","year":"2019","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.jacadv.2025.101684_bib36","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1148\/radiol.2021210246","article-title":"Right ventricular function at cardiac MRI predicts cardiovascular events in patients with an implantable cardioverter-defibrillator","volume":"301","author":"Jimenez-Juan","year":"2021","journal-title":"Radiology"},{"key":"10.1016\/j.jacadv.2025.101684_bib37","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.jcmg.2021.11.029","article-title":"An explainable machine learning approach reveals prognostic significance of right ventricular dysfunction in nonischemic cardiomyopathy","volume":"15","author":"Fahmy","year":"2022","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.jacadv.2025.101684_bib38","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.jacc.2012.05.005","article-title":"Where genome meets phenome: rationale for integrating genetic and protein biomarkers in the diagnosis and management of dilated cardiomyopathy and heart failure","volume":"60","author":"Piran","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacadv.2025.101684_bib39","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1161\/CIRCIMAGING.111.968024","article-title":"Combined cardiac magnetic resonance imaging and C-reactive protein levels identify a cohort at low risk for defibrillator firings and death","volume":"5","author":"Wu","year":"2012","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.jacadv.2025.101684_bib40","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1161\/CIRCEP.111.968057","article-title":"Plasma biomarkers for prediction of sudden cardiac death: another piece of the risk stratification puzzle?","volume":"5","author":"Havm\u00f6ller","year":"2012","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.jacadv.2025.101684_bib41","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1038\/s44161-022-00041-9","article-title":"Arrhythmic sudden death survival prediction using deep learning analysis of scarring in the heart","volume":"1","author":"Popescu","year":"2022","journal-title":"Nat Cardiovasc Res"},{"key":"10.1016\/j.jacadv.2025.101684_bib42","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1056\/NEJMoa1211107","article-title":"Reduction in inappropriate therapy and mortality through ICD programming","volume":"367","author":"Moss","year":"2012","journal-title":"N\u00a0Engl J Med"}],"container-title":["JACC: Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772963X25001012?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772963X25001012?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T06:35:51Z","timestamp":1745476551000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772963X25001012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["S2772963X25001012"],"URL":"https:\/\/doi.org\/10.1016\/j.jacadv.2025.101684","relation":{},"ISSN":["2772-963X"],"issn-type":[{"value":"2772-963X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Radiomic Cardiac MRI Signatures for\u00a0Predicting Ventricular Arrhythmias in\u00a0Patients With Nonischemic Dilated\u00a0Cardiomyopathy","name":"articletitle","label":"Article Title"},{"value":"JACC: Advances","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacadv.2025.101684","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}],"article-number":"101684"}}