{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T03:16:41Z","timestamp":1782962201761,"version":"3.54.5"},"reference-count":33,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:00:00Z","timestamp":1745539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Advances"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.jacadv.2025.101832","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T17:40:02Z","timestamp":1748281202000},"page":"101832","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"P1","title":["Association of Tricuspid Regurgitation With Mortality in Heart Failure With Left-Sided Heart Disease"],"prefix":"10.1016","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7573-7176","authenticated-orcid":false,"given":"Mitsunobu","family":"Kitamura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuaki","family":"Amami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Yaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7470-2863","authenticated-orcid":false,"given":"Kouya","family":"Okabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuyuki","family":"Shiraishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0129-7219","authenticated-orcid":false,"given":"Ryo","family":"Nakamaru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3430-4614","authenticated-orcid":false,"given":"Yuji","family":"Nagatomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayumi","family":"Goda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiru","family":"Nomoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7596-7633","authenticated-orcid":false,"given":"Atsushi","family":"Mizuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munehisa","family":"Sakamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumiko K.","family":"Ichihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kohno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun","family":"Kohsaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsutomu","family":"Yoshikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacadv.2025.101832_bib1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.jacc.2003.09.036","article-title":"Impact of tricuspid regurgitation on long-term survival","volume":"43","author":"Nath","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacadv.2025.101832_bib2","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/j.jcmg.2014.07.018","article-title":"Clinical outcome of isolated tricuspid regurgitation","volume":"7","author":"Topilsky","year":"2014","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.jacadv.2025.101832_bib3","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.122.011958","article-title":"Atrial functional tricuspid regurgitation: novel definition and impact on prognosis","volume":"15","author":"Schlotter","year":"2022","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jacadv.2025.101832_bib4","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1093\/ehjci\/jead016","article-title":"Prognostic implications of atrial vs. ventricular functional tricuspid regurgitation","volume":"24","author":"Galloo","year":"2023","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jacadv.2025.101832_bib5","doi-asserted-by":"crossref","first-page":"e578","DOI":"10.1161\/CIR.0000000000000560","article-title":"Evaluation and management of right-sided heart failure: a scientific statement from the American Heart Association","volume":"137","author":"Konstam","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.jacadv.2025.101832_bib6","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.jcin.2019.10.023","article-title":"Combined tricuspid and mitral versus isolated mitral valve repair for severe MR and TR: an analysis from the TriValve and TRAMI registries","volume":"13","author":"Mehr","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jacadv.2025.101832_bib7","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1056\/NEJMoa2115961","article-title":"Concomitant tricuspid repair in patients with degenerative mitral regurgitation","volume":"386","author":"Gammie","year":"2022","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacadv.2025.101832_bib8","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1056\/NEJMoa2300525","article-title":"Transcatheter repair for patients with tricuspid regurgitation","volume":"388","author":"Sorajja","year":"2023","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.jacadv.2025.101832_bib9","doi-asserted-by":"crossref","first-page":"e25","DOI":"10.1016\/j.jacc.2020.11.018","article-title":"2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Joint Committee on clinical practice guidelines","volume":"77","author":"Otto","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacadv.2025.101832_bib10","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1093\/eurheartj\/ehx391","article-title":"2017 ESC\/EACTS guidelines for the management of valvular heart disease","volume":"38","author":"Baumgartner","year":"2017","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacadv.2025.101832_bib11","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.jacc.2019.04.028","article-title":"Surgery does not improve survival in patients with isolated severe tricuspid regurgitation","volume":"74","author":"Axtell","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacadv.2025.101832_bib12","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1016\/j.jcin.2021.09.021","article-title":"Health status after transcatheter tricuspid valve repair in patients with functional tricuspid regurgitation","volume":"14","author":"Kitamura","year":"2021","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jacadv.2025.101832_bib13","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.ijcard.2017.02.070","article-title":"Current use of guideline-based medical therapy in elderly patients admitted with acute heart failure with reduced ejection fraction and its impact on event-free survival","volume":"235","author":"Akita","year":"2017","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jacadv.2025.101832_bib14","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ejim.2019.01.014","article-title":"Association of renin-angiotensin system inhibitors with long-term outcomes in patients with systolic heart failure and moderate-to-severe kidney function impairment","volume":"62","author":"Higuchi","year":"2019","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.jacadv.2025.101832_bib15","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-20892-3","article-title":"Association between class of foundational medication for heart failure and prognosis in heart failure with reduced\/mildly reduced ejection fraction","volume":"12","author":"Ito","year":"2022","journal-title":"Sci Rep"},{"key":"10.1016\/j.jacadv.2025.101832_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijcard.2023.131161","article-title":"Association of pre-hospital precipitating factors with short- and long-term outcomes of acute heart failure patients: a report from the WET-HF2 registry","volume":"389","author":"Ichihara","year":"2023","journal-title":"Int J Cardiol"},{"issue":"2","key":"10.1016\/j.jacadv.2025.101832_bib17","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1002\/ehf2.14635","article-title":"Treatment patterns and trajectories in patients after acute heart failure hospitalization","volume":"11","author":"Nakamaru","year":"2023","journal-title":"ESC Heart Fail"},{"key":"10.1016\/j.jacadv.2025.101832_bib18","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.122.027689","article-title":"Phenotyping of elderly patients with heart failure focused on noncardiac conditions: a latent class analysis from a multicenter registry of patients hospitalized with heart failure","volume":"12","author":"Nakamaru","year":"2023","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.jacadv.2025.101832_bib19","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1002\/ejhf.2115","volume":"23","author":"Bozkurt","year":"2021","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jacadv.2025.101832_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2018.06.004","article-title":"Guidelines for performing a comprehensive transthoracic echocardiographic examination in adults: recommendations from the American Society of Echocardiography","volume":"32","author":"Mitchell","year":"2019","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.jacadv.2025.101832_bib21","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.echo.2017.01.007","article-title":"Recommendations for noninvasive evaluation of native valvular regurgitation: a report from the American Society of Echocardiography developed in collaboration with the society for cardiovascular magnetic resonance","volume":"30","author":"Zoghbi","year":"2017","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.jacadv.2025.101832_bib22","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.jacc.2008.09.048","article-title":"Tricuspid regurgitation in mitral valve disease incidence, prognostic implications, mechanism, and management","volume":"53","author":"Shiran","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacadv.2025.101832_bib23","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1093\/eurheartj\/ehaa192","article-title":"Functional tricuspid regurgitation of degenerative mitral valve disease: a crucial determinant of survival","volume":"41","author":"Essayagh","year":"2020","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacadv.2025.101832_bib24","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1093\/ehjci\/jey105","article-title":"Impact of concomitant tricuspid regurgitation on long-term outcomes in severe aortic stenosis","volume":"20","author":"Amano","year":"2019","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jacadv.2025.101832_bib25","doi-asserted-by":"crossref","first-page":"e002073","DOI":"10.1161\/CIRCINTERVENTIONS.114.002073","article-title":"Effect of tricuspid regurgitation and the right heart on survival after transcatheter aortic valve replacement: insights from the Placement of Aortic Transcatheter Valves II inoperable cohort","volume":"8","author":"Lindman","year":"2015","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jacadv.2025.101832_bib26","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/j.jacc.2020.07.035","article-title":"Impact of tricuspid regurgitation on clinical outcomes: the COAPT trial","volume":"76","author":"Hahn","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacadv.2025.101832_bib27","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1161\/CIRCIMAGING.122.014988","article-title":"Association of tricuspid regurgitation with outcome in acute heart failure","volume":"16","author":"Cocianni","year":"2023","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.jacadv.2025.101832_bib28","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/0735-1097(94)90017-5","article-title":"Significant tricuspid regurgitation is a marker for adverse outcome in patients undergoing percutaneous balloon mitral valvuloplasty","volume":"24","author":"Sagie","year":"1994","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacadv.2025.101832_bib29","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1093\/ehjci\/jeu114","article-title":"Association of tricuspid regurgitation with clinical and echocardiographic outcomes after percutaneous mitral valve repair with the MitraClip System: 30-day and 12-month follow-up from the GRASP Registry","volume":"15","author":"Ohno","year":"2014","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jacadv.2025.101832_bib30","doi-asserted-by":"crossref","first-page":"e57","DOI":"10.1016\/j.jacc.2014.02.536","article-title":"2014 AHA\/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association task force on practice guidelines","volume":"63","author":"Nishimura","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacadv.2025.101832_bib31","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1002\/ejhf.2637","article-title":"Evolution of tricuspid regurgitation after transcatheter edge-to-edge mitral valve repair for secondary mitral regurgitation and its impact on mortality","volume":"24","author":"Adamo","year":"2022","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jacadv.2025.101832_bib32","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1016\/j.jacc.2023.08.008","article-title":"Tricuspid valve academic research consortium definitions for tricuspid regurgitation and trial endpoints","volume":"82","author":"Hahn","year":"2023","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacadv.2025.101832_bib33","doi-asserted-by":"crossref","first-page":"I453","DOI":"10.1161\/CIRCULATIONAHA.104.524421","article-title":"Progression of tricuspid regurgitation after repaired functional ischemic mitral regurgitation","volume":"112","author":"Matsunaga","year":"2005","journal-title":"Circulation"}],"container-title":["JACC: Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772963X25002510?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772963X25002510?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T03:57:52Z","timestamp":1750910272000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772963X25002510"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S2772963X25002510"],"URL":"https:\/\/doi.org\/10.1016\/j.jacadv.2025.101832","relation":{},"ISSN":["2772-963X"],"issn-type":[{"value":"2772-963X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of Tricuspid Regurgitation With Mortality in Heart Failure With Left-Sided Heart Disease","name":"articletitle","label":"Article Title"},{"value":"JACC: Advances","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacadv.2025.101832","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}],"article-number":"101832"}}