{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T15:52:03Z","timestamp":1762098723879,"version":"3.44.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T00:00:00Z","timestamp":1642464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Asia"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.jacasi.2021.12.009","type":"journal-article","created":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T14:43:44Z","timestamp":1650984224000},"page":"341-350","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"P2","title":["Incidence, Prediction, and Outcomes of Major Bleeding After Percutaneous Coronary Intervention in Chinese Patients"],"prefix":"10.1016","volume":"2","author":[{"given":"Andrew Kei-Yan","family":"Ng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pauline Yeung","family":"Ng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"April","family":"Ip","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian Wood-Hay","family":"Ling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lap-Tin","family":"Lam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung-Wah","family":"Siu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacasi.2021.12.009_bib1","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1016\/j.jacc.2015.01.047","article-title":"Association of spontaneous bleeding and myocardial infarction with long-term mortality after percutaneous coronary intervention","volume":"65","author":"Kazi","year":"2015","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacasi.2021.12.009_bib2","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.jacc.2015.06.1323","article-title":"Incidence, predictors, and impact of post-discharge bleeding after percutaneous coronary intervention","volume":"66","author":"Genereux","year":"2015","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacasi.2021.12.009_bib3","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1016\/j.jcin.2016.04.037","article-title":"The impact of timing of ischemic and hemorrhagic events on mortality after percutaneous coronary intervention: the ADAPT-DES study","volume":"9","author":"Brener","year":"2016","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacasi.2021.12.009_bib4","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jacc.2020.05.031","article-title":"Post-discharge bleeding and mortality following acute coronary syndromes with or without PCI","volume":"76","author":"Marquis-Gravel","year":"2020","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacasi.2021.12.009_bib5","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.115.003519","article-title":"Postdischarge bleeding after percutaneous coronary intervention and subsequent mortality and myocardial infarction: insights from the HMO Research Network-Stent Registry","volume":"9","author":"Valle","year":"2016","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jacasi.2021.12.009_bib6","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1016\/j.jacc.2015.03.003","article-title":"Benefits and risks of extended duration dual antiplatelet therapy after PCI in patients with and without acute myocardial infarction","volume":"65","author":"Yeh","year":"2015","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacasi.2021.12.009_bib7","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1056\/NEJMoa1500857","article-title":"Long-term use of ticagrelor in patients with prior myocardial infarction","volume":"372","author":"Bonaca","year":"2015","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacasi.2021.12.009_bib8","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/nrcardio.2014.104","article-title":"Expert consensus document: World Heart Federation expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI","volume":"11","author":"Levine","year":"2014","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jacasi.2021.12.009_bib9","doi-asserted-by":"crossref","first-page":"620","DOI":"10.3904\/kjim.2015.30.5.620","article-title":"A\u00a0pharmacodynamic study of the optimal P2Y12 inhibitor regimen for East Asian patients with acute coronary syndrome","volume":"30","author":"Lee","year":"2015","journal-title":"Korean J Intern Med"},{"key":"10.1016\/j.jacasi.2021.12.009_bib10","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s11886-014-0485-4","article-title":"\u201cEast Asian paradox\u201d: challenge for the current antiplatelet strategy of \u201cone-guideline-fits-all races\u201d in acute coronary syndrome","volume":"16","author":"Jeong","year":"2014","journal-title":"Curr Cardiol Rep"},{"key":"10.1016\/j.jacasi.2021.12.009_bib11","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1055\/s-0038-1676545","article-title":"Racial differences in ischaemia\/bleeding risk trade-off during anti-platelet therapy: individual patient level landmark meta-analysis from seven RCTs","volume":"119","author":"Kang","year":"2019","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jacasi.2021.12.009_bib12","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.4244\/EIJ-D-20-00345","article-title":"High bleeding risk and clinical outcomes in East Asian patients undergoing percutaneous coronary intervention: the PENDULUM registry","volume":"16","author":"Nakamura","year":"2021","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jacasi.2021.12.009_bib13","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1161\/CIRCULATIONAHA.119.040167","article-title":"Defining high bleeding risk in patients undergoing percutaneous coronary intervention","volume":"140","author":"Urban","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.jacasi.2021.12.009_bib14","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1056\/NEJMoa1908419","article-title":"Ticagrelor with or without aspirin in high-risk patients after PCI","volume":"381","author":"Mehran","year":"2019","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacasi.2021.12.009_bib15","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1001\/jama.2020.7580","article-title":"Effect of ticagrelor monotherapy vs ticagrelor with aspirin on major bleeding and cardiovascular events in patients with acute coronary syndrome: the TICO randomized clinical trial","volume":"323","author":"Kim","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.jacasi.2021.12.009_bib16","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1056\/NEJMoa1910021","article-title":"Polymer-based or polymer-free stents in patients at high bleeding risk","volume":"382","author":"Windecker","year":"2020","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacasi.2021.12.009_bib17","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1056\/NEJMoa1907096","article-title":"A\u00a0genotype-guided strategy for oral P2Y12 inhibitors in primary PCI","volume":"381","author":"Claassens","year":"2019","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacasi.2021.12.009_bib18","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1056\/NEJMoa1817083","article-title":"Antithrombotic therapy after acute coronary syndrome or PCI in atrial fibrillation","volume":"380","author":"Lopes","year":"2019","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacasi.2021.12.009_bib19","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1111\/j.1538-7836.2005.01204.x","volume":"3","author":"Schulman","year":"2005","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.jacasi.2021.12.009_bib20","first-page":"804","article-title":"Trade-off of myocardial infarction vs. bleeding types on mortality after acute coronary syndrome: lessons from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) randomized trial","volume":"38","author":"Valgimigli","year":"2017","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacasi.2021.12.009_bib21","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s12872-020-01352-0","article-title":"Systematic review and meta-analysis of the prognostic impact of cancer among patients with acute coronary syndrome and\/or percutaneous coronary intervention","volume":"20","author":"Roule","year":"2020","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.jacasi.2021.12.009_bib22","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1186\/s12891-017-1606-1","article-title":"The impact of hip fracture on mortality in Estonia: a retrospective population-based cohort study","volume":"18","author":"Jurisson","year":"2017","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.jacasi.2021.12.009_bib23","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1055\/s-0039-1688792","article-title":"Development and validation of an ischemic and bleeding risk evaluation tool in East Asian patients receiving percutaneous coronary intervention","volume":"119","author":"Kang","year":"2019","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jacasi.2021.12.009_bib24","article-title":"Prediction of thrombotic and bleeding events after percutaneous coronary intervention: CREDO-Kyoto Thrombotic and Bleeding Risk Scores","volume":"7","author":"Natsuaki","year":"2018","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jacasi.2021.12.009_bib25","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1007\/s12325-020-01526-4","article-title":"Real-world bleeding and ischemic events in Asian patients on P2Y12-inhibitors after percutaneous coronary intervention: a national claims data analysis","volume":"38","author":"Lee","year":"2021","journal-title":"Adv Ther"},{"key":"10.1016\/j.jacasi.2021.12.009_bib26","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2013-000021","article-title":"Major bleeding after percutaneous coronary intervention and risk of subsequent mortality: a systematic review and meta-analysis","volume":"1","author":"Kwok","year":"2014","journal-title":"Open Heart"},{"key":"10.1016\/j.jacasi.2021.12.009_bib27","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jcin.2007.12.006","article-title":"Major femoral bleeding complications after percutaneous coronary intervention: incidence, predictors, and impact on long-term survival among 17,901 patients treated at the Mayo Clinic from 1994 to 2005","volume":"1","author":"Doyle","year":"2008","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacasi.2021.12.009_bib28","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1016\/j.jacc.2011.07.021","article-title":"Impact of in-hospital major bleeding on late clinical outcomes after primary percutaneous coronary intervention in acute myocardial infarction the HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) trial","volume":"58","author":"Suh","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacasi.2021.12.009_bib29","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.114.002053","article-title":"Clinical impact of gastrointestinal bleeding in patients undergoing percutaneous coronary interventions","volume":"8","author":"Koskinas","year":"2015","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jacasi.2021.12.009_bib30","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1056\/NEJMoa1007964","article-title":"Clopidogrel with or without omeprazole in coronary artery disease","volume":"363","author":"Bhatt","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacasi.2021.12.009_bib31","doi-asserted-by":"crossref","first-page":"e02","DOI":"10.15420\/ecr.2020.40","article-title":"2020 Asian Pacific Society of Cardiology Consensus Recommendations on the use of P2Y12 receptor antagonists in the Asia-Pacific region","volume":"16","author":"Tan","year":"2021","journal-title":"Eur Cardiol"},{"key":"10.1016\/j.jacasi.2021.12.009_bib32","doi-asserted-by":"crossref","first-page":"e26","DOI":"10.15420\/ecr.2020.45","article-title":"2020 Asian Pacific Society of Cardiology Consensus Recommendations on antithrombotic management for high-risk chronic coronary syndrome","volume":"16","author":"Tan","year":"2021","journal-title":"Eur Cardiol"},{"key":"10.1016\/j.jacasi.2021.12.009_bib33","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1177\/0003319717730168","article-title":"Higher risk of bleeding in Asians presenting with ST-segment elevation myocardial infarction: analysis of the National Inpatient Sample Database","volume":"69","author":"Misumida","year":"2018","journal-title":"Angiology"},{"key":"10.1016\/j.jacasi.2021.12.009_bib34","doi-asserted-by":"crossref","first-page":"21345","DOI":"10.1038\/s41598-020-78400-4","article-title":"Impact of bleeding during dual antiplatelet therapy in patients with coronary artery disease","volume":"10","author":"Tung","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.jacasi.2021.12.009_bib35","doi-asserted-by":"crossref","first-page":"537","DOI":"10.4070\/kcj.2018.0166","article-title":"The evolving concept of dual antiplatelet therapy after percutaneous coronary intervention: focus on unique feature of East Asian and \u201cAsian paradox\u201d","volume":"48","author":"Kang","year":"2018","journal-title":"Korean Circ J"},{"key":"10.1016\/j.jacasi.2021.12.009_bib36","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.ahj.2015.09.017","article-title":"An international comparison of patients undergoing percutaneous coronary intervention: a collaborative study of the National Cardiovascular Data Registry (NCDR) and Japan Cardiovascular Database-Keio interhospital Cardiovascular Studies (JCD-KiCS)","volume":"170","author":"Kohsaka","year":"2015","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacasi.2021.12.009_bib37","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/S0140-6736(17)30397-5","article-title":"Derivation and validation of the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy (PRECISE-DAPT) score: a pooled analysis of individual-patient datasets from clinical trials","volume":"389","author":"Costa","year":"2017","journal-title":"Lancet"}],"container-title":["JACC: Asia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772374722000096?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772374722000096?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T09:57:48Z","timestamp":1757411868000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772374722000096"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["S2772374722000096"],"URL":"https:\/\/doi.org\/10.1016\/j.jacasi.2021.12.009","relation":{},"ISSN":["2772-3747"],"issn-type":[{"type":"print","value":"2772-3747"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Incidence, Prediction, and Outcomes of Major Bleeding After Percutaneous Coronary Intervention in Chinese Patients","name":"articletitle","label":"Article Title"},{"value":"JACC: Asia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacasi.2021.12.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}]}}