{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:35:32Z","timestamp":1793061332309,"version":"4.5.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Asia"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.jacasi.2026.06.043","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T04:19:35Z","timestamp":1787804375000},"page":"2276-2289","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"P1","title":["Physiological Patterns of Coronary Artery Disease and Drug-Coated Balloon Performance"],"prefix":"10.1016","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2755-2094","authenticated-orcid":false,"given":"Simone","family":"Fezzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo Luca","family":"Gurgoglione","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Gitto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hesham Abu","family":"Abied","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faisal","family":"Sharif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Venturi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi Alberto","family":"Iossa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek","family":"Bezubka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0509-6075","authenticated-orcid":false,"given":"Sylwia","family":"Iwanczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1220-9496","authenticated-orcid":false,"given":"Wojciech","family":"Wanha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micha\u0142","family":"Hawranek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maksymilian","family":"Mielczarek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Wa\u0144czura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilya","family":"Litovchik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0163-6929","authenticated-orcid":false,"given":"Antoinette","family":"Monayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7611-8641","authenticated-orcid":false,"given":"Ettore","family":"Ventura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Galli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuomas T.","family":"Rissanen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"Ribichini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Colombo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Collet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5808-7810","authenticated-orcid":false,"given":"Bernardo","family":"Cortese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"21","key":"10.1016\/j.jacasi.2026.06.043_bib1","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.1016\/j.jcin.2022.07.015","article-title":"Functional patterns of coronary disease: diffuse, focal, and serial lesions","volume":"15","author":"Scarsini","year":"2022","journal-title":"JACC Cardiovasc Interv"},{"issue":"24","key":"10.1016\/j.jacasi.2026.06.043_bib2","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1016\/j.jcin.2022.09.048","article-title":"Differential improvement in angina and health-related quality of life after PCI in focal and diffuse coronary artery disease","volume":"15","author":"Collet","year":"2022","journal-title":"JACC Cardiovasc Interv"},{"issue":"10","key":"10.1016\/j.jacasi.2026.06.043_bib3","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.123.013185","article-title":"Integrated assessment of computational coronary physiology from a single angiographic view in patients undergoing TAVI","volume":"16","author":"Fezzi","year":"2023","journal-title":"Circ Cardiovasc Interv"},{"issue":"3","key":"10.1016\/j.jacasi.2026.06.043_bib4","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s12928-020-00673-3","article-title":"Inter-observer differences in interpretation of coronary pressure-wire pullback data by non-expert interventional cardiologists","volume":"36","author":"Warisawa","year":"2021","journal-title":"Cardiovasc Interv Ther"},{"issue":"4","key":"10.1016\/j.jacasi.2026.06.043_bib5","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1093\/ehjdh\/ztaf031","article-title":"Validation of machine learning angiography-derived physiological pattern of coronary artery disease","volume":"6","author":"Zhu","year":"2025","journal-title":"Eur Heart J Digit Health"},{"issue":"14","key":"10.1016\/j.jacasi.2026.06.043_bib6","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1016\/j.jacc.2019.07.072","article-title":"Measurement of hyperemic pullback pressure gradients to characterize patterns of coronary atherosclerosis","volume":"74","author":"Collet","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"12","key":"10.1016\/j.jacasi.2026.06.043_bib7","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1007\/s00392-024-02500-8","article-title":"Angiography-derived physiological patterns of coronary artery disease: implications with post-stenting physiology and long-term clinical outcomes","volume":"113","author":"Fezzi","year":"2024","journal-title":"Clin Res Cardiol"},{"issue":"16","key":"10.1016\/j.jacasi.2026.06.043_bib8","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1016\/j.jcin.2021.06.013","article-title":"Physiological distribution and local severity of coronary artery disease and outcomes after percutaneous coronary intervention","volume":"14","author":"Shin","year":"2021","journal-title":"JACC Cardiovasc Interv"},{"issue":"7","key":"10.1016\/j.jacasi.2026.06.043_bib9","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/j.jcin.2022.01.012","article-title":"Treatment of coronary De Novo lesions by a sirolimus- or paclitaxel-coated balloon","volume":"15","author":"Ahmad","year":"2022","journal-title":"JACC Cardiovasc Interv"},{"issue":"17","key":"10.1016\/j.jacasi.2026.06.043_bib10","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1093\/eurheartj\/ehaf002","article-title":"Individual patient data meta-analysis of paclitaxel-coated balloons vs. drug-eluting stents for small-vessel coronary artery disease: the ANDROMEDA study","volume":"46","author":"Fezzi","year":"2025","journal-title":"Eur Heart J"},{"issue":"9","key":"10.1016\/j.jacasi.2026.06.043_bib11","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1038\/s41569-024-01014-0","article-title":"Illusion of revascularization: does anyone achieve optimal revascularization during percutaneous coronary intervention?","volume":"21","author":"Fezzi","year":"2024","journal-title":"Nat Rev Cardiol"},{"issue":"6","key":"10.1016\/j.jacasi.2026.06.043_bib12","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.jacc.2019.11.058","article-title":"Stent-related adverse events >1 year after percutaneous coronary intervention","volume":"75","author":"Madhavan","year":"2020","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"10.1016\/j.jacasi.2026.06.043_bib13","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.jacc.2020.05.026","article-title":"10-Year outcomes from a randomized trial of polymer-free versus durable polymer drug-eluting coronary stents","volume":"76","author":"Kufner","year":"2020","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.jacasi.2026.06.043_bib14","doi-asserted-by":"crossref","first-page":"28","DOI":"10.4244\/AIJ-D-25-00057","article-title":"Angiographic and functional assessment after paclitaxel or sirolimus drug-coated balloons for de novo coronary artery disease in small vessels: PICCOLETO VI study","volume":"12","author":"Fezzi","year":"2026","journal-title":"AsiaIntervention"},{"key":"10.1016\/j.jacasi.2026.06.043_bib15","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.amjcard.2024.12.015","article-title":"Predictors and long-term prognostic significance of bailout stenting during percutaneous coronary interventions with sirolimus-coated balloon: a subanalysis of the eastbourne study","volume":"239","author":"Gurgoglione","year":"2025","journal-title":"Am J Cardiol"},{"issue":"11","key":"10.1016\/j.jacasi.2026.06.043_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/jpm12111798","article-title":"In vivo validation of a novel computational approach to assess microcirculatory resistance based on a single angiographic view","volume":"12","author":"Fan","year":"2022","journal-title":"J Pers Med"},{"issue":"11","key":"10.1016\/j.jacasi.2026.06.043_bib17","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.121.024903","article-title":"Prognostic implications of prestent pullback pressure gradient and poststent quantitative flow ratio in patients undergoing percutaneous coronary intervention","volume":"11","author":"Dai","year":"2022","journal-title":"J Am Heart Assoc"},{"issue":"11","key":"10.1016\/j.jacasi.2026.06.043_bib18","doi-asserted-by":"crossref","first-page":"e891","DOI":"10.4244\/EIJ-D-23-00516","article-title":"Preprocedural physiological assessment of coronary disease patterns to predict haemodynamic outcomes post-PCI","volume":"19","author":"Kotoku","year":"2023","journal-title":"EuroIntervention"},{"issue":"26","key":"10.1016\/j.jacasi.2026.06.043_bib19","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1093\/eurheartj\/ehaf029","article-title":"Definitions and standardized endpoints for the use of drug-coated balloon in coronary artery disease: consensus document of the Drug Coated Balloon Academic Research Consortium","volume":"46","author":"Fezzi","year":"2025","journal-title":"Eur Heart J"},{"issue":"19","key":"10.1016\/j.jacasi.2026.06.043_bib20","doi-asserted-by":"crossref","first-page":"e1116","DOI":"10.4244\/EIJ-E-25-00021","article-title":"Definitions and standardized endpoints for the use of drug-coated balloon in coronary artery disease: consensus document of the Drug Coated Balloon Academic Research Consortium","volume":"21","author":"Fezzi","year":"2025","journal-title":"Eurointervention"},{"key":"10.1016\/j.jacasi.2026.06.043_bib21","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ahj.2016.10.016","article-title":"Clinical and angiographic predictors of persistently ischemic fractional flow reserve after percutaneous revascularization","volume":"184","author":"Agarwal","year":"2017","journal-title":"Am Heart J"},{"issue":"20","key":"10.1016\/j.jacasi.2026.06.043_bib22","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1016\/j.jcin.2019.06.003","article-title":"Prognostic value of QFR measured immediately after successful stent implantation: the international multicenter prospective HAWKEYE study","volume":"12","author":"Biscaglia","year":"2019","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jacasi.2026.06.043_bib23","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.ijcard.2022.01.054","article-title":"Post-PCI outcomes predicted by pre-intervention simulation of residual quantitative flow ratio using augmented reality","volume":"352","author":"Zhang","year":"2022","journal-title":"Int J Cardiol"},{"issue":"6","key":"10.1016\/j.jacasi.2026.06.043_bib24","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1055\/s-0037-1601306","article-title":"Coronary artery bypass surgery in diffuse advanced coronary artery disease: 1-year clinical and angiographic results","volume":"66","author":"Dourado","year":"2018","journal-title":"Thorac Cardiovasc Surg"},{"issue":"8","key":"10.1016\/j.jacasi.2026.06.043_bib25","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.116.005233","article-title":"Prognostic value of fractional flow reserve measured immediately after drug-eluting stent implantation","volume":"10","author":"Piroth","year":"2017","journal-title":"Circ Cardiovasc Interv"},{"issue":"3","key":"10.1016\/j.jacasi.2026.06.043_bib26","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.120.009681","article-title":"Impact of poststenting fractional flow reserve on long-term clinical outcomes: the FFR-SEARCH study","volume":"14","author":"Diletti","year":"2021","journal-title":"Circ Cardiovasc Interv"},{"issue":"1","key":"10.1016\/j.jacasi.2026.06.043_bib27","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jcin.2021.09.042","article-title":"1-Year outcomes of blinded physiological assessment of residual ischemia after successful PCI: DEFINE PCI trial","volume":"15","author":"Patel","year":"2022","journal-title":"JACC Cardiovasc Interv"},{"issue":"20","key":"10.1016\/j.jacasi.2026.06.043_bib28","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1016\/j.jcin.2019.08.009","article-title":"Clinical implication of quantitative flow ratio after percutaneous coronary intervention for 3-Vessel disease","volume":"12","author":"Kogame","year":"2019","journal-title":"JACC Cardiovasc Interv"},{"issue":"12","key":"10.1016\/j.jacasi.2026.06.043_bib29","doi-asserted-by":"crossref","first-page":"e1324","DOI":"10.4244\/EIJ-D-18-00071","article-title":"What are the causes of a suboptimal FFR after coronary stent deployment? Insights from a consecutive series using OCT imaging","volume":"14","author":"Wolfrum","year":"2018","journal-title":"EuroIntervention"},{"issue":"2","key":"10.1016\/j.jacasi.2026.06.043_bib30","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.118.007030","article-title":"Explanation of postprocedural fractional flow reserve below 0.85","volume":"12","author":"van Zandvoort","year":"2019","journal-title":"Circ Cardiovasc Interv"},{"issue":"45","key":"10.1016\/j.jacasi.2026.06.043_bib31","doi-asserted-by":"crossref","first-page":"4656","DOI":"10.1093\/eurheartj\/ehab449","article-title":"Post-stenting fractional flow reserve vs coronary angiography for optimization of percutaneous coronary intervention (TARGET-FFR)","volume":"42","author":"Collison","year":"2021","journal-title":"Eur Heart J"},{"issue":"24","key":"10.1016\/j.jacasi.2026.06.043_bib32","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.1016\/j.jcin.2020.08.035","article-title":"Drug-coated balloon versus drug-eluting stent for small coronary vessel disease: PICCOLETO II randomized clinical trial","volume":"13","author":"Cortese","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"issue":"10457","key":"10.1016\/j.jacasi.2026.06.043_bib33","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/S0140-6736(24)01594-0","article-title":"Drug-coated balloon angioplasty with rescue stenting versus intended stenting for the treatment of patients with de novo coronary artery lesions (REC-CAGEFREE I): an open-label, randomised, non-inferiority trial","volume":"404","author":"Gao","year":"2024","journal-title":"Lancet"},{"issue":"23","key":"10.1016\/j.jacasi.2026.06.043_bib34","doi-asserted-by":"crossref","first-page":"2884","DOI":"10.1016\/j.jcin.2023.09.026","article-title":"A prospective randomized trial comparing sirolimus-coated balloon with paclitaxel-coated balloon in De Novo small vessels","volume":"16","author":"Ninomiya","year":"2023","journal-title":"JACC Cardiovasc Interv"},{"issue":"21","key":"10.1016\/j.jacasi.2026.06.043_bib35","doi-asserted-by":"crossref","first-page":"e1322","DOI":"10.4244\/EIJ-D-23-00868","article-title":"A randomised trial of sirolimus-versus paclitaxel-coated balloons for de novo coronary lesions","volume":"20","author":"Scheller","year":"2024","journal-title":"EuroIntervention"},{"issue":"3","key":"10.1016\/j.jacasi.2026.06.043_bib36","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.jcin.2022.10.049","article-title":"Clinical impact of drug-coated balloon-based percutaneous coronary intervention in patients with multivessel coronary artery disease","volume":"16","author":"Shin","year":"2023","journal-title":"JACC Cardiovasc Interv"},{"issue":"19","key":"10.1016\/j.jacasi.2026.06.043_bib37","doi-asserted-by":"crossref","first-page":"e1116","DOI":"10.4244\/EIJ-E-25-00021","article-title":"Drug-coated balloons for coronary bifurcation lesions","volume":"21","author":"Fezzi","year":"2025","journal-title":"EuroIntervention"},{"issue":"10194","key":"10.1016\/j.jacasi.2026.06.043_bib38","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/S0140-6736(19)31126-2","article-title":"Drug-coated balloon for treatment of de-novo coronary artery lesions in patients with high bleeding risk (DEBUT): a single-blind, randomised, non-inferiority trial","volume":"394","author":"Rissanen","year":"2019","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.jacasi.2026.06.043_bib39","doi-asserted-by":"crossref","first-page":"591","DOI":"10.4244\/EIJV10I5A102","article-title":"Coronary artery treatment with paclitaxel-coated balloon using a BTHC excipient: clinical results of the international real-world DELUX registry","volume":"10","author":"Toelg","year":"2014","journal-title":"EuroIntervention"},{"issue":"2","key":"10.1016\/j.jacasi.2026.06.043_bib40","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.jcin.2023.10.032","article-title":"Coronary physiology guidance vs conventional angiography for optimization of percutaneous coronary intervention: the AQVA-II trial","volume":"17","author":"Biscaglia","year":"2024","journal-title":"JACC Cardiovasc Interv"},{"issue":"10","key":"10.1016\/j.jacasi.2026.06.043_bib41","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.124.014362","article-title":"Prognostic value of murray law-based QFR (\u03bcQFR)-Guided virtual PCI in patients with physiological ischemia","volume":"17","author":"Chen","year":"2024","journal-title":"Circ Cardiovasc Interv"},{"issue":"13","key":"10.1016\/j.jacasi.2026.06.043_bib42","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/j.jcin.2024.04.014","article-title":"Intravascular ultrasound vs angiography-guided drug-coated balloon angioplasty: the ULTIMATE \u2162 Trial","volume":"17","author":"Gao","year":"2024","journal-title":"JACC Cardiovasc Interv"}],"container-title":["JACC: Asia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772374726006046?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772374726006046?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:22:12Z","timestamp":1793060532000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772374726006046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":42,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S2772374726006046"],"URL":"https:\/\/doi.org\/10.1016\/j.jacasi.2026.06.043","relation":{},"ISSN":["2772-3747"],"issn-type":[{"value":"2772-3747","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Physiological Patterns of Coronary Artery Disease and Drug-Coated Balloon Performance","name":"articletitle","label":"Article Title"},{"value":"JACC: Asia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacasi.2026.06.043","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}]}}