{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:34:38Z","timestamp":1790735678966,"version":"4.1.0"},"reference-count":58,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T00:00:00Z","timestamp":1685059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002347","name":"BMBF Bonn","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002428","name":"FWF","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002428","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010109","name":"Medizinische Universit\u00e4t Graz","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010109","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"NHMRC","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000970","name":"Stem Cells Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000970","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001081","name":"University of Newcastle Hunter Medical Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001081","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"DFG","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001674","name":"Fondation Leducq","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001674","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Basic to Translational Science"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.jacbts.2023.05.010","type":"journal-article","created":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T14:31:06Z","timestamp":1692196266000},"page":"1539-1554","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction"],"prefix":"10.1016","volume":"8","author":[{"given":"Sean A.","family":"Hardy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Liesinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph","family":"Patrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Poettler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lavinia","family":"Rech","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juergen","family":"Gindlhuber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishani S.","family":"Mabotuwana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DiyaaEldin","family":"Ashour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena","family":"Stangl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Bigland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy A.","family":"Murtha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm R.","family":"Starkey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Scherr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip M.","family":"Hansbro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Hoefler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"Campos Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clement","family":"Cochain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard P.","family":"Harvey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Birner-Gruenberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3919-5269","authenticated-orcid":false,"given":"Andrew J.","family":"Boyle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2840-6454","authenticated-orcid":false,"given":"Peter P.","family":"Rainer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacbts.2023.05.010_bib1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0212230","article-title":"Novel role of extracellular matrix protein 1 (ECM1) in cardiac aging and myocardial infarction","volume":"14","author":"Hardy","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.jacbts.2023.05.010_bib2","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1161\/CIRCHEARTFAILURE.114.001151","article-title":"Metabolomic analysis of pressure-overloaded and infarcted mouse hearts","volume":"7","author":"Sansbury","year":"2014","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jacbts.2023.05.010_bib3","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/s41569-018-0077-x","article-title":"The interstitium in cardiac repair: role of the immune\u2013stromal cell interplay","volume":"15","author":"Forte","year":"2018","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jacbts.2023.05.010_bib4","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.1805829115","article-title":"Profiling proliferative cells and their progeny in damaged murine hearts","volume":"115","author":"Kretzschmar","year":"2018","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jacbts.2023.05.010_bib5","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.stem.2019.12.004","article-title":"Toward the goal of human heart regeneration","volume":"26","author":"Sadek","year":"2020","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.jacbts.2023.05.010_bib6","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.bbamcr.2012.08.023","article-title":"Fibroblasts in post-infarction inflammation and cardiac repair","volume":"1833","author":"Chen","year":"2013","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.jacbts.2023.05.010_bib7","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1093\/cvr\/cvu062","article-title":"Crosstalk between fibroblasts and inflammatory cells","volume":"102","author":"Van Linthout","year":"2014","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jacbts.2023.05.010_bib8","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2020.00301","article-title":"Leukocyte-dependent regulation of cardiac fibrosis","volume":"11","author":"Okyere","year":"2020","journal-title":"Front Physiol"},{"key":"10.1016\/j.jacbts.2023.05.010_bib9","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.3389\/fphys.2020.529075","article-title":"The dynamic interplay between cardiac inflammation and fibrosis","volume":"11","author":"Thomas","year":"2020","journal-title":"Front Physiol"},{"key":"10.1016\/j.jacbts.2023.05.010_bib10","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00395-017-0622-5","article-title":"IL-10 improves cardiac remodeling after myocardial infarction by stimulating M2 macrophage polarization and fibroblast activation","volume":"112","author":"Jung","year":"2017","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.jacbts.2023.05.010_bib11","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1016\/j.clinthera.2020.09.006","article-title":"The cardiac injury immune response as a target for regenerative and cellular therapies","volume":"42","author":"Hume","year":"2020","journal-title":"Clin Ther"},{"key":"10.1016\/j.jacbts.2023.05.010_bib12","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s11897-017-0343-y","article-title":"From inflammation to fibrosis\u2014molecular and cellular mechanisms of myocardial tissue remodelling and perspectives on differential treatment opportunities","volume":"14","author":"Suthahar","year":"2017","journal-title":"Curr Heart Fail Rep"},{"key":"10.1016\/j.jacbts.2023.05.010_bib13","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/s41467-019-14263-2","article-title":"Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair","volume":"11","author":"Sim\u00f5es","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.jacbts.2023.05.010_bib14","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s00395-018-0686-x","article-title":"Mapping macrophage polarization over the myocardial infarction time continuum","volume":"113","author":"Mouton","year":"2018","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.jacbts.2023.05.010_bib15","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1006\/geno.1997.4918","article-title":"The human extracellular matrix gene 1 (ECM1): genomic structure, cDNA cloning, expression pattern, and chromosomal localization","volume":"45","author":"Smits","year":"1997","journal-title":"Genomics"},{"key":"10.1016\/j.jacbts.2023.05.010_bib16","series-title":"Textbook of Aging Skin","first-page":"91","article-title":"The extracellular matrix protein 1 (ECM1) in molecular-based skin biology","author":"Oyama","year":"2017"},{"key":"10.1016\/j.jacbts.2023.05.010_bib17","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/ni.1983","article-title":"ECM1 controls TH2 cell egress from lymph nodes through re-expression of S1P","volume":"12","author":"Li","year":"2011","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jacbts.2023.05.010_bib18","doi-asserted-by":"crossref","first-page":"8621","DOI":"10.1073\/pnas.1801196115","article-title":"Extracellular matrix protein 1 promotes follicular helper T cell differentiation and antibody production","volume":"115","author":"He","year":"2018","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jacbts.2023.05.010_bib19","doi-asserted-by":"crossref","first-page":"3083","DOI":"10.1073\/pnas.1912774117","article-title":"ECM1 is an essential factor for the determination of M1 macrophage polarization in IBD in response to LPS stimulation","volume":"117","author":"Zhang","year":"2020","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jacbts.2023.05.010_bib20","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.43882","article-title":"Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury","volume":"8","author":"Farbehi","year":"2019","journal-title":"eLife"},{"key":"10.1016\/j.jacbts.2023.05.010_bib21","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1038\/s41586-021-03674-1","article-title":"A\u00a0transcriptional switch governs fibroblast activation in heart disease","volume":"595","author":"Alexanian","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.jacbts.2023.05.010_bib22","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/s41586-020-2797-4","article-title":"Cells of the adult human heart","volume":"588","author":"Litvi\u0148ukov\u00e1","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.jacbts.2023.05.010_bib23","doi-asserted-by":"crossref","first-page":"D442","DOI":"10.1093\/nar\/gky1106","article-title":"The PRIDE database and related tools and resources in 2019: improving support for quantification data","volume":"47","author":"Perez-Riverol","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jacbts.2023.05.010_bib24","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1164\/rccm.201609-1830OC","article-title":"Role for NLRP3 inflammasome-mediated, IL-1\u03b2-dependent responses in severe, steroid-resistant asthma","volume":"196","author":"Kim","year":"2017","journal-title":"Am J Resp Crit Care Med"},{"key":"10.1016\/j.jacbts.2023.05.010_bib25","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1093\/cvr\/cvab112","article-title":"Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling","volume":"118","author":"Ljubojevi\u0107-Holzer","year":"2022","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jacbts.2023.05.010_bib26","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.immuni.2018.06.008","article-title":"Hyaluronan receptor LYVE-1-expressing macrophages maintain arterial tone through hyaluronan-mediated regulation of smooth muscle cell collagen","volume":"49","author":"Lim","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.jacbts.2023.05.010_bib27","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/8696543","article-title":"Galectin-1 as an emerging mediator of cardiovascular inflammation: mechanisms and therapeutic opportunities","volume":"2018","author":"Seropian","year":"2018","journal-title":"Mediators of Inflamm"},{"key":"10.1016\/j.jacbts.2023.05.010_bib28","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3389\/fcvm.2019.00051","article-title":"Low density lipoprotein receptor-related protein-1 in cardiac inflammation and infarct healing","volume":"6","author":"Potere","year":"2019","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.jacbts.2023.05.010_bib29","first-page":"561","article-title":"Low-density lipoprotein receptor\u2013related protein-1 is a therapeutic target in acute myocardial infarction","volume":"2","author":"Toldo","year":"2017","journal-title":"J\u00a0Am Coll Cardiol Basic Trans Science"},{"key":"10.1016\/j.jacbts.2023.05.010_bib30","doi-asserted-by":"crossref","first-page":"D523","DOI":"10.1093\/nar\/gkac1052","article-title":"UniProt: the Universal Protein Knowledgebase in 2023","volume":"51","author":"The UniProt","year":"2023","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jacbts.2023.05.010_bib31","doi-asserted-by":"crossref","first-page":"E9280","DOI":"10.1073\/pnas.1712560114","article-title":"Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway","volume":"114","author":"Mizoguchi","year":"2017","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jacbts.2023.05.010_bib32","first-page":"497","article-title":"PTP-PEST targets a novel tyrosine site in p120 catenin to control epithelial cell motility and Rho GTPase activity","volume":"127","author":"Espejo","year":"2014","journal-title":"J\u00a0Cell Sci"},{"key":"10.1016\/j.jacbts.2023.05.010_bib33","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1002\/embr.201337868","article-title":"p120-catenin differentially regulates cell migration by Rho-dependent intracellular and secreted signals","volume":"15","author":"Epifano","year":"2014","journal-title":"EMBO Rep"},{"key":"10.1016\/j.jacbts.2023.05.010_bib34","first-page":"198","article-title":"Neutrophil\u2013macrophage cross-talk in acute myocardial infarction","volume":"38","author":"Frodermann","year":"2017","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacbts.2023.05.010_bib35","article-title":"Fibulin-1c regulates transforming growth factor-\u03b2 activation in pulmonary tissue fibrosis","volume":"5","author":"Liu","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.jacbts.2023.05.010_bib36","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.jdermsci.2020.06.010","article-title":"Gene silencing of extracellular matrix protein 1 (ECM1) results in phenotypic alterations of dermal fibroblasts reminiscent of clinical features of lichen sclerosus","volume":"100","author":"Utsunomiya","year":"2020","journal-title":"J\u00a0Dermatol Sci"},{"key":"10.1016\/j.jacbts.2023.05.010_bib37","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1093\/hmg\/11.7.833","article-title":"Lipoid proteinosis maps to 1q21 and is caused by mutations in the extracellular matrix protein 1 gene (ECM1)","volume":"11","author":"Hamada","year":"2002","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jacbts.2023.05.010_bib38","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1053\/j.gastro.2019.07.036","article-title":"ECM1 prevents activation of transforming growth factor beta, hepatic stellate cells, and fibrogenesis in mice","volume":"157","author":"Fan","year":"2019","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jacbts.2023.05.010_bib39","doi-asserted-by":"crossref","first-page":"777","DOI":"10.14309\/ajg.0000000000000237","article-title":"Serum protein biomarkers of fibrosis aid in risk stratification of future stricturing complications in pediatric Crohn\u2019s disease","volume":"114","author":"Wu","year":"2019","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jacbts.2023.05.010_bib40","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.semcancer.2019.07.020","article-title":"P120 and E-cadherin: double-edged swords in tumor metastasis","volume":"60","author":"Venhuizen","year":"2020","journal-title":"Semin Cancer Biol"},{"key":"10.1016\/j.jacbts.2023.05.010_bib41","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1038\/s41374-020-0415-6","article-title":"ECM1 secreted by HER2-overexpressing breast cancer cells promotes formation of a vascular niche accelerating cancer cell migration and invasion","volume":"100","author":"Steinhaeuser","year":"2020","journal-title":"Lab Invest"},{"key":"10.1016\/j.jacbts.2023.05.010_bib42","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1038\/nature01148","article-title":"Rho GTPases in cell biology","volume":"420","author":"Etienne-Manneville","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.jacbts.2023.05.010_bib43","doi-asserted-by":"crossref","first-page":"9905","DOI":"10.1073\/pnas.1115063109","article-title":"Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA\u2013Myosin II signaling","volume":"109","author":"Itoh","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jacbts.2023.05.010_bib44","article-title":"Human Rho guanine nucleotide exchange factor 11 (ARHGEF11) regulates dendritic morphogenesis","volume":"18","author":"Mizuki","year":"2017","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jacbts.2023.05.010_bib45","doi-asserted-by":"crossref","first-page":"3390","DOI":"10.4049\/jimmunol.1302525","article-title":"The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration","volume":"192","author":"Lessey-Morillon","year":"2014","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jacbts.2023.05.010_bib46","first-page":"277","article-title":"PTP-PEST controls EphA3 activation and ephrin-induced cytoskeletal remodelling","volume":"129","author":"Mansour","year":"2016","journal-title":"J\u00a0Cell Sci"},{"key":"10.1016\/j.jacbts.2023.05.010_bib47","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.3390\/cancers12102895","article-title":"CD99-PTPN12 axis suppresses actin cytoskeleton-mediated dimerization of epidermal growth factor receptor","volume":"12","author":"Lee","year":"2020","journal-title":"Cancers"},{"key":"10.1016\/j.jacbts.2023.05.010_bib48","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1042\/BCJ20200511","article-title":"Protein tyrosine phosphatases in cell adhesion","volume":"478","author":"Young","year":"2021","journal-title":"Biochem J"},{"key":"10.1016\/j.jacbts.2023.05.010_bib49","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s10585-016-9827-5","article-title":"Extracellular matrix 1 (ECM1) regulates the actin cytoskeletal architecture of aggressive breast cancer cells in part via S100A4 and Rho-family GTPases","volume":"34","author":"G\u00f3mez-Contreras","year":"2017","journal-title":"Clin Exp Metastasis"},{"key":"10.1016\/j.jacbts.2023.05.010_bib50","doi-asserted-by":"crossref","first-page":"4230","DOI":"10.1038\/s41467-021-24315-1","article-title":"Extracellular matrix protein-1 secretory isoform promotes ovarian cancer through increasing alternative mRNA splicing and stemness","volume":"12","author":"Yin","year":"2021","journal-title":"Nat Commun"},{"key":"10.1016\/j.jacbts.2023.05.010_bib51","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1161\/CIRCRESAHA.119.315088","article-title":"LRP1 deficiency in vascular SMC leads to pulmonary arterial hypertension that is reversed by PPAR\u03b3 activation","volume":"124","author":"Calvier","year":"2019","journal-title":"Circ Res"},{"key":"10.1016\/j.jacbts.2023.05.010_bib52","doi-asserted-by":"crossref","first-page":"e448","DOI":"10.1371\/journal.pone.0000448","article-title":"LRP1 functions as an atheroprotective integrator of TGF\u03b2 and PDFG signals in the vascular wall: implications for Marfan syndrome","volume":"2","author":"Boucher","year":"2007","journal-title":"PLoS One"},{"key":"10.1016\/j.jacbts.2023.05.010_bib53","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.29292","article-title":"LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis","volume":"6","author":"Xian","year":"2017","journal-title":"Elife"},{"key":"10.1016\/j.jacbts.2023.05.010_bib54","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/35023588","article-title":"Inhibition of RhoA by p120 catenin","volume":"2","author":"Anastasiadis","year":"2000","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.jacbts.2023.05.010_bib55","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.cell.2006.09.046","article-title":"p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho","volume":"127","author":"Wildenberg","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.jacbts.2023.05.010_bib56","doi-asserted-by":"crossref","first-page":"23307","DOI":"10.1074\/jbc.M603127200","article-title":"Dual regulation of Rho and Rac by p120 catenin controls adipocyte plasma membrane trafficking","volume":"281","author":"Hou","year":"2006","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jacbts.2023.05.010_bib57","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.bbamcr.2015.10.008","article-title":"Phosphorylation and isoform use in p120-catenin during development and tumorigenesis","volume":"1863","author":"Hong","year":"2016","journal-title":"Biochim Biophys Acta Mol Cell Res"},{"key":"10.1016\/j.jacbts.2023.05.010_bib58","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0235337","article-title":"p120-catenin phosphorylation status alters E-cadherin mediated cell adhesion and ability of tumor cells to metastasize","volume":"15","author":"Mendonsa","year":"2020","journal-title":"PLoS One"}],"container-title":["JACC: Basic to Translational Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452302X23002310?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452302X23002310?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:26:28Z","timestamp":1762820788000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452302X23002310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":58,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S2452302X23002310"],"URL":"https:\/\/doi.org\/10.1016\/j.jacbts.2023.05.010","relation":{},"ISSN":["2452-302X"],"issn-type":[{"value":"2452-302X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction","name":"articletitle","label":"Article Title"},{"value":"JACC: Basic to Translational Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacbts.2023.05.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}]}}