{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:44:13Z","timestamp":1792097053868,"version":"4.4.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T00:00:00Z","timestamp":1701216000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014717","name":"National Natural Science Foundation of China National Outstanding Youth Science Fund Project","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014717","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JACC: Basic to Translational Science"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.jacbts.2023.11.002","type":"journal-article","created":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T14:02:46Z","timestamp":1706104966000},"page":"380-395","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Primate Model Carrying LMNA Mutation Develops Dilated Cardiomyopathy"],"prefix":"10.1016","volume":"9","author":[{"given":"Xiang","family":"Luo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Mo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ningning","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lizhu","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengsheng","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaoyan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shulin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiumeng","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chu","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqiang","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinglong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhigang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weizhi","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengzu","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangping","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuyu","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacbts.2023.11.002_bib1","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/S0140-6736(09)62023-7","article-title":"Dilated cardiomyopathy","volume":"375","author":"Jefferies","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.jacbts.2023.11.002_bib2","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1161\/CIRCEP.111.962050","article-title":"Dilated cardiomyopathy","volume":"6","author":"Lakdawala","year":"2013","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib3","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1136\/heartjnl-2017-312338","article-title":"Lamin and the heart","volume":"104","author":"Captur","year":"2018","journal-title":"Heart"},{"key":"10.1016\/j.jacbts.2023.11.002_bib4","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00392-016-1033-6","article-title":"Genotype-phenotype associations in dilated cardiomyopathy: meta-analysis on more than 8000 individuals","volume":"106","author":"Kayvanpour","year":"2017","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib5","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1016\/j.jacc.2022.08.804","article-title":"Prognostic prediction of genotype vs phenotype in genetic cardiomyopathies","volume":"80","author":"Paldino","year":"2022","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib6","first-page":"451","article-title":"Characteristics of ventricular tachycardia and long-term treatment outcome in patients with dilated cardiomyopathy complicated by lamin A\/C gene mutations","volume":"74","author":"Hasebe","year":"2019","journal-title":"J\u00a0Cardiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib7","doi-asserted-by":"crossref","first-page":"4325","DOI":"10.1093\/hmg\/dds265","article-title":"Abnormal p38\u03b1 mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A\/C gene mutation","volume":"21","author":"Muchir","year":"2012","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jacbts.2023.11.002_bib8","first-page":"131","article-title":"Targeting the histone demethylase LSD1 prevents cardiomyopathy in a mouse model of laminopathy","author":"Gu\u00e9nantin","year":"2021","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jacbts.2023.11.002_bib9","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1093\/hmg\/ddi017","article-title":"Mouse model carrying H222P-lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies","volume":"14","author":"Arimura","year":"2005","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jacbts.2023.11.002_bib10","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/s41586-022-04587-3","article-title":"Cell transcriptomic atlas of the non-human primate macaca fascicularis","volume":"604","author":"Han","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.jacbts.2023.11.002_bib11","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/nbt.4162","article-title":"Human embryonic stem cell-derived cardiomyocytes restore function in infarcted hearts of non-human primates","volume":"36","author":"Liu","year":"2018","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib12","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1093\/eurheartj\/ehv727","article-title":"Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the esc working group on myocardial and pericardial diseases","volume":"37","author":"Pinto","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacbts.2023.11.002_bib13","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1161\/CIRCULATIONAHA.121.055690","article-title":"Multifaceted spatial and functional zonation of cardiac cells in adult human heart","volume":"145","author":"Chen","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.jacbts.2023.11.002_bib14","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/nature15393","article-title":"A\u00a0global reference for human genetic variation","volume":"526","author":"Auton","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.jacbts.2023.11.002_bib15","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/nature19057","article-title":"Analysis of protein-coding genetic variation in 60,706 humans","volume":"536","author":"Lek","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.jacbts.2023.11.002_bib16","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1038\/nprot.2009.86","article-title":"Predicting the effects of coding non-synonymous variants on protein function using the sift algorithm","volume":"4","author":"Kumar","year":"2009","journal-title":"Nat Protoc"},{"key":"10.1016\/j.jacbts.2023.11.002_bib17","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nmeth0410-248","article-title":"A\u00a0method and server for predicting damaging missense mutations","volume":"7","author":"Adzhubei","year":"2010","journal-title":"Nat Methods"},{"key":"10.1016\/j.jacbts.2023.11.002_bib18","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1038\/nmeth0810-575","article-title":"Mutationtaster evaluates disease-causing potential of sequence alterations","volume":"7","author":"Schwarz","year":"2010","journal-title":"Nat Methods"},{"key":"10.1016\/j.jacbts.2023.11.002_bib19","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/ng.2892","article-title":"A\u00a0general framework for estimating the relative pathogenicity of human genetic variants","volume":"46","author":"Kircher","year":"2014","journal-title":"Nat Genet"},{"key":"10.1016\/j.jacbts.2023.11.002_bib20","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/ng.3144","article-title":"A\u00a0recurrent de novo mutation in KCNC1 causes progressive myoclonus epilepsy","volume":"47","author":"Muona","year":"2015","journal-title":"Nat Genet"},{"key":"10.1016\/j.jacbts.2023.11.002_bib21","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/gim.2015.30","article-title":"Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology","volume":"17","author":"Richards","year":"2015","journal-title":"Genet Med"},{"key":"10.1016\/j.jacbts.2023.11.002_bib22","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1016\/j.amjcard.2014.02.031","article-title":"Usefulness of electrocardiographic parameters for risk prediction in arrhythmogenic right ventricular dysplasia","volume":"113","author":"Saguner","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib23","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1016\/j.jacc.2021.03.008","article-title":"Myocardial histopathology in patients with obstructive hypertrophic cardiomyopathy","volume":"77","author":"Cui","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib24","doi-asserted-by":"crossref","first-page":"17663","DOI":"10.1073\/pnas.1006563107","article-title":"Transgenic rhesus monkeys produced by gene transfer into early-cleavage-stage embryos using a simian immunodeficiency virus-based vector","volume":"107","author":"Niu","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jacbts.2023.11.002_bib25","first-page":"483","article-title":"The influence of anesthesia on cardiac repolarization","volume":"78","author":"Owczuk","year":"2012","journal-title":"Minerva Anestesiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib26","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1056\/NEJMoa1110186","article-title":"Truncations of titin causing dilated cardiomyopathy","volume":"366","author":"Herman","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacbts.2023.11.002_bib27","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1046\/j.1540-8167.2004.40096.x","article-title":"Electrophysiological and histopathological characteristics of progressive atrioventricular block accompanied by familial dilated cardiomyopathy caused by a novel mutation of lamin A\/C gene","volume":"16","author":"Otomo","year":"2005","journal-title":"J\u00a0Cardiovasc Electrophysiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib28","doi-asserted-by":"crossref","first-page":"4722","DOI":"10.1038\/s41467-021-24849-4","article-title":"Disrupting the linc complex by AAV mediated gene transduction prevents progression of lamin induced cardiomyopathy","volume":"12","author":"Chai","year":"2021","journal-title":"Nat Commun"},{"key":"10.1016\/j.jacbts.2023.11.002_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0155421","article-title":"Exome sequencing identifies a novel lmna splice-site mutation and multigenic heterozygosity of potential modifiers in a family with sick sinus syndrome, dilated cardiomyopathy, and sudden cardiac death","volume":"11","author":"Zaragoza","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jacbts.2023.11.002_bib30","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.carpath.2017.06.012","article-title":"Ultrastructural aspects of vacuolar degeneration of cardiomyocytes in human endomyocardial biopsies","volume":"30","author":"Takemura","year":"2017","journal-title":"Cardiovasc Pathol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib31","doi-asserted-by":"crossref","first-page":"761","DOI":"10.3389\/fphys.2020.00761","article-title":"The broad spectrum of LMNA cardiac diseases: from molecular mechanisms to clinical phenotype","volume":"11","author":"Crasto","year":"2020","journal-title":"Front Physiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib32","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.778982","article-title":"Phenotypic variability in iPSC-induced cardiomyocytes and cardiac fibroblasts carrying diverse lmna mutations","volume":"12","author":"Yang","year":"2021","journal-title":"Front Physiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib33","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/s41586-019-1406-x","article-title":"Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy","volume":"572","author":"Lee","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.jacbts.2023.11.002_bib34","doi-asserted-by":"crossref","first-page":"7886","DOI":"10.1038\/s41467-022-35639-x","article-title":"Actin-microtubule cytoskeletal interplay mediated BY MRTF-A\/SRF signaling promotes dilated cardiomyopathy caused by LMNA mutations","volume":"13","author":"Le Dour","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.jacbts.2023.11.002_bib35","doi-asserted-by":"crossref","first-page":"6663","DOI":"10.1038\/s41467-022-34366-7","article-title":"Lamin A\/C-dependent chromatin architecture safeguards na\u00efve pluripotency to prevent aberrant cardiovascular cell fate and function","volume":"13","author":"Wang","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.jacbts.2023.11.002_bib36","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1161\/CIRCRESAHA.118.314238","article-title":"DNA damage response\/tp53 pathway is activated and contributes to the pathogenesis of dilated cardiomyopathy associated with lmna (lamin A\/C) mutations","volume":"124","author":"Chen","year":"2019","journal-title":"Circ Res"},{"key":"10.1016\/j.jacbts.2023.11.002_bib37","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1161\/CIRCRESAHA.122.320246","article-title":"Large and small animal models of heart failure with reduced ejection fraction","volume":"130","author":"Pilz","year":"2022","journal-title":"Circ Res"},{"key":"10.1016\/j.jacbts.2023.11.002_bib38","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1161\/CIRCRESAHA.122.320258","article-title":"Animal models to study cardiac arrhythmias","volume":"130","author":"Blackwell","year":"2022","journal-title":"Circ Res"},{"key":"10.1016\/j.jacbts.2023.11.002_bib39","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1038\/s41591-020-1087-x","article-title":"Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs","volume":"26","author":"Schneider","year":"2020","journal-title":"Nat Med"},{"key":"10.1016\/j.jacbts.2023.11.002_bib40","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abo3123","article-title":"Cloning and base editing of GFP transgenic rhesus monkey and off-target analysis","volume":"8","author":"Kang","year":"2022","journal-title":"Sci Adv"},{"key":"10.1016\/j.jacbts.2023.11.002_bib41","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jacc.2022.04.035","article-title":"LMNA variants and risk of adult-onset cardiac disease","volume":"80","author":"Lazarte","year":"2022","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib42","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/nrcardio.2017.190","article-title":"Role of titin in cardiomyopathy: from DNA variants to patient stratification","volume":"15","author":"Ware","year":"2018","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib43","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1152\/physrev.00047.2005","article-title":"Nuclear lamins: Laminopathies and their role in premature ageing","volume":"86","author":"Broers","year":"2006","journal-title":"Physiol Rev"},{"key":"10.1016\/j.jacbts.2023.11.002_bib44","doi-asserted-by":"crossref","first-page":"795","DOI":"10.4161\/auto.8901","article-title":"Autophagic degradation of nuclear components in mammalian cells","volume":"5","author":"Park","year":"2009","journal-title":"Autophagy"},{"key":"10.1016\/j.jacbts.2023.11.002_bib45","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1093\/hmg\/ddr592","article-title":"LMNA variants cause cytoplasmic distribution of\u00a0nuclear pore proteins in drosophila and human muscle","volume":"21","author":"Dialynas","year":"2012","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jacbts.2023.11.002_bib46","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1161\/CIRCRESAHA.120.317685","article-title":"Multiscale analysis of extracellular matrix remodeling in the failing heart","volume":"128","author":"Perestrelo","year":"2021","journal-title":"Circ Res"},{"key":"10.1016\/j.jacbts.2023.11.002_bib47","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/nyas.12216","article-title":"The pig as a valuable model for testing the effect of resveratrol to prevent cardiovascular disease","volume":"1290","author":"Elmadhun","year":"2013","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jacbts.2023.11.002_bib48","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1002\/ejhf.2463","article-title":"The response to cardiac resynchronization therapy in LMNA cardiomyopathy","volume":"24","author":"Sidhu","year":"2022","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jacbts.2023.11.002_bib49","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/nrcardio.2016.173","article-title":"Diagnosis, pathophysiology, and management of exercise-induced arrhythmias","volume":"14","author":"Guasch","year":"2017","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jacbts.2023.11.002_bib50","doi-asserted-by":"crossref","first-page":"4740","DOI":"10.1172\/JCI135922","article-title":"Bet bromodomain inhibition attenuates cardiac phenotype in myocyte-specific lamin A\/C-deficient mice","volume":"130","author":"Auguste","year":"2020","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jacbts.2023.11.002_bib51","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.1038\/s41467-022-31770-x","article-title":"A\u00a0reference single-cell regulomic and transcriptomic map of cynomolgus monkeys","volume":"13","author":"Qu","year":"2022","journal-title":"Nat Commun"}],"container-title":["JACC: Basic to Translational Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452302X23005156?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452302X23005156?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:47:45Z","timestamp":1792093665000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452302X23005156"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":51,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["S2452302X23005156"],"URL":"https:\/\/doi.org\/10.1016\/j.jacbts.2023.11.002","relation":{},"ISSN":["2452-302X"],"issn-type":[{"value":"2452-302X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Primate Model Carrying LMNA Mutation Develops Dilated Cardiomyopathy","name":"articletitle","label":"Article Title"},{"value":"JACC: Basic to Translational Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacbts.2023.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}]}}