{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T02:06:28Z","timestamp":1791165988914,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2003,12,1]],"date-time":"2003-12-01T00:00:00Z","timestamp":1070236800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":3552,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2003,12]]},"DOI":"10.1016\/j.jacc.2003.06.015","type":"journal-article","created":{"date-parts":[[2003,12,3]],"date-time":"2003-12-03T06:59:35Z","timestamp":1070434775000},"page":"1994-1999","source":"Crossref","is-referenced-by-count":195,"title":["Phospholipid abnormalities in children with Barth syndrome"],"prefix":"10.1016","volume":"42","author":[{"given":"Michael","family":"Schlame","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard I","family":"Kelley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Feigenbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey A","family":"Towbin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul M","family":"Heerdt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Schieble","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald J.A","family":"Wanders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"DiMauro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.J","family":"Blanck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2003.06.015_BIB1","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0022-510X(83)90209-5","article-title":"An X-linked mitochondrial disease affecting cardiac muscle, skeletal muscle and neutrophil leukocytes","volume":"62","author":"Barth","year":"1983","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.jacc.2003.06.015_BIB2","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/S0022-3476(05)80289-6","article-title":"X-linked dilated cardiomyopathy with neutropenia, growth retardation, and 3-methylglutaconic aciduria","volume":"119","author":"Kelley","year":"1991","journal-title":"J Pediatr"},{"key":"10.1016\/j.jacc.2003.06.015_BIB3","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1023\/A:1005568609936","article-title":"X-linked cardioskeletal myopathy and neutropenia (Barth syndrome) (MIM 302060)","volume":"22","author":"Barth","year":"1999","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.jacc.2003.06.015_BIB4","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0022-3476(99)70118-6","article-title":"X-linked cardioskeletal myopathy and neutropenia (Barth syndrome)-MIM 302060","volume":"135","author":"Barth","year":"1999","journal-title":"J Pediatr"},{"key":"10.1016\/j.jacc.2003.06.015_BIB5","doi-asserted-by":"crossref","first-page":"10977","DOI":"10.1073\/pnas.90.23.10977","article-title":"Transcriptional organization of a 450-kb region of the human X chromosome in Xq28","volume":"90","author":"Bione","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jacc.2003.06.015_BIB6","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/ng0496-385","article-title":"A novel X-linked gene, G4.5, is responsible for Barth syndrome","volume":"12","author":"Bione","year":"1996","journal-title":"Nat Genet"},{"key":"10.1016\/j.jacc.2003.06.015_BIB7","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1086\/514886","article-title":"The X-linked gene G4.5 is responsible for different infantile dilated cardiomyopathies","volume":"61","author":"D'Adamo","year":"1997","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jacc.2003.06.015_BIB8","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1161\/01.CIR.103.9.1256","article-title":"Novel gene mutations in patients with left ventricular noncompaction or Barth syndrome","volume":"103","author":"Ichida","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2003.06.015_BIB9","doi-asserted-by":"crossref","first-page":"R465","DOI":"10.1016\/S0960-9822(06)00237-5","article-title":"Barth syndrome may be due to an acyltransferase deficiency","volume":"7","author":"Neuwald","year":"1997","journal-title":"Curr Biol"},{"key":"10.1016\/j.jacc.2003.06.015_BIB10","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1006\/bbrc.2000.3952","article-title":"Defective remodeling of cardiolipin and phosphatidylglycerol in Barth syndrome","volume":"279","author":"Vreken","year":"2000","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jacc.2003.06.015_BIB11","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/ana.10176","article-title":"Deficiency of tetralinoleoyl-cardiolipin in Barth syndrome","volume":"51","author":"Schlame","year":"2002","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jacc.2003.06.015_BIB12","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1093\/clinchem\/48.9.1390","article-title":"Quantitative and compositional study of cardiolipin in platelets by electrospray ionization mass spectrometry","volume":"48","author":"Valianpour","year":"2002","journal-title":"Clin Chem"},{"key":"10.1016\/j.jacc.2003.06.015_BIB13","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1067\/mpd.2002.129174","article-title":"Cardiolipin deficiency in X-linked cardioskeletal myopathy and neutropenia (Barth syndrome, MIM 302060)","volume":"141","author":"Valianpour","year":"2002","journal-title":"J Pediatr"},{"key":"10.1016\/j.jacc.2003.06.015_BIB14","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1136\/jmg.32.5.383","article-title":"X-linked fatal infantile cardiomyopathy maps to Xq28 and is possibly allelic to Barth syndrome","volume":"32","author":"Gedeon","year":"1995","journal-title":"J Med Genet"},{"key":"10.1016\/j.jacc.2003.06.015_BIB15","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1086\/514879","article-title":"Neonatal, lethal noncompaction of the left ventricular myocardium is allelic with Barth syndrome","volume":"61","author":"Bleyl","year":"1997","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jacc.2003.06.015_BIB16","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/1096-8628(2001)9999:9999<::AID-AJMG1136>3.0.CO;2-X","article-title":"Barth's syndrome-like disorder","volume":"99","author":"De Kremer","year":"2001","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.jacc.2003.06.015_BIB17","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jacc.2003.06.015_BIB18","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1139\/o59-099","article-title":"A rapid method of total lipid extraction and purification","volume":"37","author":"Bligh","year":"1959","journal-title":"Can J Biochem Physiol"},{"key":"10.1016\/j.jacc.2003.06.015_BIB19","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1042\/bj2720589","article-title":"Lysocardiolipin formation and reacylation in isolated rat liver mitochondria","volume":"272","author":"Schlame","year":"1990","journal-title":"Biochem J"},{"key":"10.1016\/j.jacc.2003.06.015_BIB20","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/S0021-9258(18)70226-3","article-title":"Phosphorus assay in column chromatography","volume":"234","author":"Bartlett","year":"1959","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jacc.2003.06.015_BIB21","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1016\/S0022-2275(20)33404-0","article-title":"Microanalysis of cardiolipin in small biopsies including skeletal muscle from patients with mitochondrial disease","volume":"40","author":"Schlame","year":"1999","journal-title":"J Lipid Res"},{"key":"10.1016\/j.jacc.2003.06.015_BIB22","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/BF02535701","article-title":"Quantitative analysis of polyenoic phospholipid molecular species by high-performance liquid chromatography","volume":"21","author":"Takamura","year":"1986","journal-title":"Lipids"},{"key":"10.1016\/j.jacc.2003.06.015_BIB23","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1432-1033.1991.tb16144.x","article-title":"Molecular species of cardiolipin in relation to other mitochondrial phospholipids. Is there an acyl specificity of the interaction between cardiolipin and the ADP\/ATP carrier?","volume":"199","author":"Schlame","year":"1991","journal-title":"Eur J Biochem"},{"key":"10.1016\/j.jacc.2003.06.015_BIB24","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0163-7827(00)00005-9","article-title":"The biosynthesis and functional role of cardiolipin","volume":"39","author":"Schlame","year":"2000","journal-title":"Progr Lipid Res"},{"key":"10.1016\/j.jacc.2003.06.015_BIB25","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S1096-7192(02)00195-6","article-title":"Mutation analysis of the G4.5 gene in patients with isolated left ventricular noncompaction","volume":"77","author":"Chen","year":"2002","journal-title":"Mol Genet Metab"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109703012403?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109703012403?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,13]],"date-time":"2021-06-13T05:51:11Z","timestamp":1623563471000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109703012403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,12]]},"references-count":25,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2003,12]]}},"alternative-id":["S0735109703012403"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2003.06.015","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2003,12]]}}}