{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T18:52:23Z","timestamp":1791139943886,"version":"4.1.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":2207,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2007,7]]},"DOI":"10.1016\/j.jacc.2007.03.029","type":"journal-article","created":{"date-parts":[[2007,6,19]],"date-time":"2007-06-19T11:09:18Z","timestamp":1182251358000},"page":"48-55","source":"Crossref","is-referenced-by-count":147,"title":["Retinal Arteriolar Narrowing and Left Ventricular Remodeling"],"prefix":"10.1016","volume":"50","author":[{"given":"Ning","family":"Cheung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Bluemke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Richey","family":"Sharrett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.M. Amirul","family":"Islam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Frances","family":"Cotch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara E.K.","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael H.","family":"Criqui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tien Yin","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2007.03.029_bib1","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1016\/S0140-6736(05)66621-4","article-title":"Heart failure","volume":"365","author":"McMurray","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2007.03.029_bib2","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1056\/NEJMra021498","article-title":"Heart failure","volume":"348","author":"Jessup","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2007.03.029_bib3","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1056\/NEJM199005313222203","article-title":"Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study","volume":"322","author":"Levy","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2007.03.029_bib4","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1161\/01.CIR.0000036014.90197.FA","article-title":"Left ventricular remodeling after primary coronary angioplasty: patterns of left ventricular dilation and long-term prognostic implications","volume":"106","author":"Bolognese","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.03.029_bib5","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1161\/01.CIR.81.4.1161","article-title":"Ventricular remodeling after myocardial infarction","volume":"81","author":"Pfeffer","year":"1990","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.03.029_bib6","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/0735-1097(94)00424-O","article-title":"Adverse prognostic significance of concentric remodeling of the left ventricle in hypertensive patients with normal left ventricular mass","volume":"25","author":"Verdecchia","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2007.03.029_bib7","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1161\/01.CIR.86.2.431","article-title":"Effects of the angiotensin converting enzyme inhibitor enalapril on the long-term progression of left ventricular dysfunction in patients with heart failure","volume":"86","author":"Konstam","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.03.029_bib8","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1161\/01.CIR.91.10.2573","article-title":"Effects of long-term enalapril therapy on cardiac structure and function in patients with left ventricular dysfunction","volume":"91","author":"Greenberg","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.03.029_bib9","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/S0735-1097(97)00012-0","article-title":"Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease","volume":"29","author":"Doughty","year":"1997","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2007.03.029_bib10","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1016\/S0735-1097(00)01006-8","article-title":"Antiremodeling effects on the left ventricle during beta-blockade with metoprolol in the treatment of chronic heart failure","volume":"36","author":"Groenning","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2007.03.029_bib11","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/S0140-6736(06)68074-4","article-title":"Controversies in ventricular remodelling","volume":"367","author":"Opie","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2007.03.029_bib12","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0735-1097(99)00630-0","article-title":"Cardiac remodeling\u2014concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling","volume":"35","author":"Cohn","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2007.03.029_bib13","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1161\/01.CIR.93.2.223","article-title":"Clinical implications of the \u2018no reflow\u2019 phenomenon","volume":"93","author":"Ito","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.03.029_bib14","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1056\/NEJMoa025050","article-title":"Coronary microvascular dysfunction and prognosis in hypertrophic cardiomyopathy","volume":"349","author":"Cecchi","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2007.03.029_bib15","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.jacc.2005.10.050","article-title":"Relevance of coronary microvascular flow impairment to long-term remodeling and systolic dysfunction in hypertrophic cardiomyopathy","volume":"47","author":"Olivotto","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2007.03.029_bib16","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1161\/01.CIR.97.8.765","article-title":"Prognostic significance of microvascular obstruction by magnetic resonance imaging in patients with acute myocardial infarction","volume":"97","author":"Wu","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.03.029_bib17","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1161\/01.CIR.101.23.2734","article-title":"Microvascular obstruction and left ventricular remodeling early after acute myocardial infarction","volume":"101","author":"Gerber","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.03.029_bib18","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1161\/01.CIR.0000118496.44135.A7","article-title":"Impact of microvascular dysfunction on left ventricular remodeling and long-term clinical outcome after primary coronary angioplasty for acute myocardial infarction","volume":"109","author":"Bolognese","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.03.029_bib19","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1001\/jama.293.1.63","article-title":"Retinopathy and risk of congestive heart failure","volume":"293","author":"Wong","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2007.03.029_bib20","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/S0735-1097(02)01983-6","article-title":"The impact of diabetic retinopathy on long-term outcome following coronary artery bypass graft surgery","volume":"40","author":"Ono","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2007.03.029_bib21","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.athoracsur.2005.07.057","article-title":"Impact of diabetic retinopathy on cardiac outcome after coronary artery bypass graft surgery: prospective observational study","volume":"81","author":"Ono","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jacc.2007.03.029_bib22","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1093\/aje\/kwf113","article-title":"Multi-ethnic study of atherosclerosis: objectives and design","volume":"156","author":"Bild","year":"2002","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jacc.2007.03.029_bib23","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.ophtha.2005.12.013","article-title":"Prevalence of age-related macular degeneration in 4 racial\/ethnic groups in the multi-ethnic study of atherosclerosis","volume":"113","author":"Klein","year":"2006","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jacc.2007.03.029_bib24","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.ajo.2005.08.063","article-title":"Diabetic retinopathy in a multi-ethnic cohort in the United States","volume":"141","author":"Wong","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jacc.2007.03.029_bib25","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1016\/S0161-6420(99)90525-0","article-title":"Methods for evaluation of retinal microvascular abnormalities associated with hypertension\/sclerosis in the Atherosclerosis Risk in Communities Study","volume":"106","author":"Hubbard","year":"1999","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jacc.2007.03.029_bib26","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/j.ophtha.2003.09.039","article-title":"Computer-assisted measurement of retinal vessel diameters in the Beaver Dam Eye Study: methodology, correlation between eyes, and effect of refractive errors","volume":"111","author":"Wong","year":"2004","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jacc.2007.03.029_bib27","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1167\/iovs.05-1539","article-title":"Retinal vascular caliber, cardiovascular risk factors, and inflammation: the Multi-Ethnic Study of Atherosclerosis (MESA)","volume":"47","author":"Wong","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jacc.2007.03.029_bib28","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1076\/ceyr.27.3.143.16049","article-title":"Revised formulas for summarizing retinal vessel diameters","volume":"27","author":"Knudtson","year":"2003","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jacc.2007.03.029_bib29","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/S0161-6420(13)38012-9","article-title":"Grading diabetic retinopathy from stereoscopic color fundus photographs\u2014an extension of the modified Airlie House classification. ETDRS report number 10. Early Treatment Diabetic Retinopathy Study Research Group","volume":"98","year":"1991","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jacc.2007.03.029_bib30","doi-asserted-by":"crossref","first-page":"S357","DOI":"10.2214\/AJR.04.1868","article-title":"Cardiovascular function in multi-ethnic study of atherosclerosis: normal values by age, sex, and ethnicity","volume":"186","author":"Natori","year":"2006","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.jacc.2007.03.029_bib31","series-title":"Multi-Ethnic Study of Atherosclerosis Field Center Manual of Operations","year":"2001"},{"key":"10.1016\/j.jacc.2007.03.029_bib32","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1148\/radiol.2362040513","article-title":"Coronary calcium measurements: effect of CT scanner type and calcium measure on rescan reproducibility\u2014MESA study","volume":"236","author":"Detrano","year":"2005","journal-title":"Radiology"},{"key":"10.1016\/j.jacc.2007.03.029_bib33","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0140-6736(04)15544-X","article-title":"Coronary calcification score: the coronary-risk impact factor","volume":"363","author":"Thompson","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2007.03.029_bib34","doi-asserted-by":"crossref","first-page":"e10","DOI":"10.1161\/01.HYP.0000231652.97173.4c","article-title":"Are narrower or wider retinal venules associated with incident hypertension?","volume":"48","author":"Liew","year":"2006","journal-title":"Hypertension"},{"key":"10.1016\/j.jacc.2007.03.029_bib35","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1093\/bmb\/ldh050","article-title":"Hypertensive retinopathy signs as risk indicators of cardiovascular morbidity and mortality","volume":"73-74","author":"Wong","year":"2005","journal-title":"Br Med Bull"},{"key":"10.1016\/j.jacc.2007.03.029_bib36","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1475-1313.2005.00288.x","article-title":"Systemic associations of retinal microvascular signs: a review of recent population-based studies","volume":"25","author":"Wong","year":"2005","journal-title":"Ophthal Physiol Opt"},{"key":"10.1016\/j.jacc.2007.03.029_bib37","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0039-6257(01)00234-X","article-title":"Retinal microvascular abnormalities and their relationship with hypertension, cardiovascular disease, and mortality","volume":"46","author":"Wong","year":"2001","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.jacc.2007.03.029_bib38","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1001\/jama.287.9.1153","article-title":"Retinal arteriolar narrowing and risk of coronary heart disease in men and women","volume":"287","author":"Wong","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2007.03.029_bib39","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/S0140-6736(01)06253-5","article-title":"Retinal microvascular abnormalities and incident stroke: the Atherosclerosis Risk in Communities Study","volume":"358","author":"Wong","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2007.03.029_bib40","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1136\/bmj.38124.682523.55","article-title":"Prospective cohort study of retinal vessel diameters and risk of hypertension","volume":"329","author":"Wong","year":"2004","journal-title":"BMJ"},{"key":"10.1016\/j.jacc.2007.03.029_bib41","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1161\/01.CIR.91.3.635","article-title":"Maximal coronary flow reserve and metabolic coronary vasodilation in patients with diabetes mellitus","volume":"91","author":"Nahser","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.03.029_bib42","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1016\/S0140-6736(04)16509-4","article-title":"Role of MRI in clinical cardiology","volume":"363","author":"Constantine","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2007.03.029_bib43","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.ajo.2005.04.040","article-title":"Effect of axial length on retinal vascular network geometry","volume":"140","author":"Patton","year":"2005","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jacc.2007.03.029_bib44","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.ajo.2004.01.035","article-title":"Does refractive error influence the association of blood pressure and retinal vessel diameters?","volume":"137","author":"Wong","year":"2004","journal-title":"Am J Ophthalmol"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109707012697?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109707012697?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,6]],"date-time":"2019-01-06T15:21:30Z","timestamp":1546788090000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109707012697"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["S0735109707012697"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2007.03.029","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2007,7]]}}}