{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:45:18Z","timestamp":1792543518296,"version":"4.5.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"13","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":1932,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1016\/j.jacc.2007.12.024","type":"journal-article","created":{"date-parts":[[2008,3,25]],"date-time":"2008-03-25T17:53:32Z","timestamp":1206467612000},"page":"1237-1246","source":"Crossref","is-referenced-by-count":875,"title":["Psychological Stress and Cardiovascular Disease"],"prefix":"10.1016","volume":"51","author":[{"given":"Joel E.","family":"Dimsdale","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2007.12.024_bib1","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0002-9149(00)01331-X","article-title":"Sudden changes in heart rate variability during the 1999 Taiwan earthquake","volume":"87","author":"Huang","year":"2001","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2007.12.024_bib2","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1097\/00006842-200107000-00003","article-title":"Effects of psychological stress and psychiatric disorders on blood coagulation and fibrinolysis: a biobehavioral pathway to coronary artery disease?","volume":"63","author":"von Kanel","year":"2001","journal-title":"Psychosomatic Med"},{"key":"10.1016\/j.jacc.2007.12.024_bib3","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0925-5710(97)00118-7","article-title":"Hemostatic activation and cardiac events after the 1995 Hanshin-Awaji Earthquake","volume":"67","author":"Matsuo","year":"1998","journal-title":"Int J Hematol"},{"key":"10.1016\/j.jacc.2007.12.024_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijcard.2007.06.039","article-title":"Impact of earthquakes on risk for pulmonary embolism","author":"Watanabe","year":"2008","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jacc.2007.12.024_bib5","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1056\/NEJM199602153340701","article-title":"Sudden cardiac death triggered by an earthquake","volume":"334","author":"Leor","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2007.12.024_bib6","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/S0002-8703(99)70406-0","article-title":"Disparate effects of the 1989 Loma Prieta and 1994 Northridge earthquakes on hospital admissions for acute myocardial infarction: importance of superimposition of triggers","volume":"137","author":"Brown","year":"1999","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacc.2007.12.024_bib7","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1097\/00006842-198009000-00003","article-title":"Short term catecholamine response to psychological stress","volume":"42","author":"Dimsdale","year":"1980","journal-title":"Psychosom Med"},{"key":"10.1016\/j.jacc.2007.12.024_bib8","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/0002-8703(94)90268-2","article-title":"Triggers of angina and ST-segment depression in ambulatory patients with coronary artery disease: evidence for an uncoupling of angina and ischemia","volume":"128","author":"Krantz","year":"1994","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacc.2007.12.024_bib9","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/S0140-6736(84)91106-1","article-title":"Silent myocardial ischaemia due to mental stress","volume":"2","author":"Deanfield","year":"1984","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2007.12.024_bib10","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1056\/NEJM198804213181601","article-title":"Mental stress and the induction of silent myocardial ischemia in patients with coronary artery disease","volume":"318","author":"Rozanski","year":"1988","journal-title":"N Engl J Med"},{"issue":"Suppl II","key":"10.1016\/j.jacc.2007.12.024_bib11","first-page":"II71","article-title":"Stress and sudden death: the case of the long QT syndrome","volume":"83","author":"Schwartz","year":"1991","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.12.024_bib12","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1001\/jama.1996.03530450041030","article-title":"Mental stress-induced myocardial ischemia and cardiac events","volume":"275","author":"Jiang","year":"1996","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2007.12.024_bib13","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1161\/01.CIR.0000014491.90666.06","article-title":"Mental stress-induced ischemia and all-cause mortality in patients with coronary artery disease: results from the psychophysiological investigations of myocardial ischemia study","volume":"105","author":"Sheps","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.12.024_bib14","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1056\/NEJMoa043046","article-title":"Neurohumoral features of myocardial stunning due to sudden emotional stress","volume":"352","author":"Wittstein","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2007.12.024_bib15","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0046-8177(80)80129-8","article-title":"Human stress cardiomyopathy","volume":"11","author":"Cebelin","year":"1980","journal-title":"Hum Pathol"},{"key":"10.1016\/j.jacc.2007.12.024_bib16","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1161\/01.CIR.0000153801.51470.EB","article-title":"Acute and reversible cardiomyopathy provoked by stress in women from the United States","volume":"111","author":"Sharkey","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.12.024_bib17","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1161\/01.CIR.101.2.158","article-title":"Destabilizing effects of mental stress on ventricular arrhythmias in patients with implantable cardioverter-defibrillators","volume":"101","author":"Lampert","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.12.024_bib18","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/j.jacc.2004.06.032","article-title":"Increased incidence of life-threatening ventricular arrhythmias in implantable defibrillator patients after the World Trade Center attack","volume":"44","author":"Steinberg","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2007.12.024_bib19","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0022-3999(98)00088-9","article-title":"Changes in daily hassles and life events and the relationship with coronary heart disease risk factors: a 2-year longitudinal study in 27\u201329 year old males and females","volume":"46","author":"Twisk","year":"1999","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.jacc.2007.12.024_bib20","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1469-8986.2006.00480.x","article-title":"Effects of perceived stress and uplifts on inflammation and coagulability","volume":"44","author":"Jain","year":"2007","journal-title":"Psychophysiology"},{"key":"10.1016\/j.jacc.2007.12.024_bib21","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1136\/bmj.37942.603970.9A","article-title":"Long term mortality after severe starvation during the siege of Leningrad: a prospective cohort study","volume":"328","author":"Sparen","year":"2004","journal-title":"BMJ"},{"key":"10.1016\/j.jacc.2007.12.024_bib22","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/S0140-6736(04)17019-0","article-title":"Association of psychosocial risk factors with risk of acute myocardial infarction in 11,119 cases and 13,646 controls from 52 countries (the INTERHEART study): case-control study","volume":"364","author":"Rosengren","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2007.12.024_bib23","doi-asserted-by":"crossref","first-page":"382","DOI":"10.2105\/AJPH.88.3.382","article-title":"Decision latitude, job strain, and myocardial infarction: a study of working men in Stockholm","volume":"88","author":"Theorell","year":"1998","journal-title":"Am J Public Health"},{"key":"10.1016\/j.jacc.2007.12.024_bib24","doi-asserted-by":"crossref","first-page":"68","DOI":"10.2105\/AJPH.88.1.68","article-title":"Two alternative job stress models and the risk of coronary artery disease","volume":"88","author":"Bosma","year":"1998","journal-title":"Am J Public Health"},{"key":"10.1016\/j.jacc.2007.12.024_bib25","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1161\/01.HYP.0000148499.54730.0d","article-title":"Job strain, ethnicity, and sympathetic nervous system activity","volume":"44","author":"Thomas","year":"2004","journal-title":"Hypertension"},{"key":"10.1016\/j.jacc.2007.12.024_bib26","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1097\/01.PSY.0000039755.23250.A7","article-title":"Influence of socioeconomic status and job control on plasma fibrinogen responses to acute mental stress","volume":"65","author":"Steptoe","year":"2003","journal-title":"Psychosom Med"},{"key":"10.1016\/j.jacc.2007.12.024_bib27","doi-asserted-by":"crossref","first-page":"3008","DOI":"10.1001\/jama.284.23.3008","article-title":"Marital stress worsens prognosis in women with coronary heart disease: the Stockholm female coronary risk study","volume":"284","author":"Orth-Gomer","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2007.12.024_bib28","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1001\/archinte.162.3.309","article-title":"Chronic work stress and marital dissolution increase risk of posttrial mortality in men from the Multiple Risk Factor Intervention trial","volume":"162","author":"Matthews","year":"2002","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jacc.2007.12.024_bib29","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1097\/01.psy.0000238214.80871.e6","article-title":"Ethnicity, perceived discrimination, and vascular reactivity to phenylephrine","volume":"68","author":"Thomas","year":"2006","journal-title":"Psychosom Med"},{"key":"10.1016\/j.jacc.2007.12.024_bib30","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1001\/jama.282.23.2215","article-title":"Caregiving as a risk factor for mortality: the caregiver health effects study","volume":"282","author":"Schulz","year":"1999","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2007.12.024_bib31","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0022-3999(98)00084-1","article-title":"Accelerated risk of hypertensive blood pressure recordings among Alzheimer caregivers","volume":"46","author":"Shaw","year":"1999","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.jacc.2007.12.024_bib32","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1159\/000081428","article-title":"Exaggerated plasma fibrin formation (D-dimer) in elderly Alzheimer caregivers as compared to non-caregiving controls","volume":"51","author":"Von Kanel","year":"2005","journal-title":"Gerontology"},{"key":"10.1016\/j.jacc.2007.12.024_bib33","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1532-5415.2005.00642.x","article-title":"Poor sleep is association with higher plasma proinflammatory cytokine interleukin-6 and procoagulant marker fibrin D-dimer in older Alzheimer caregivers","volume":"54","author":"von Kanel","year":"2006","journal-title":"J Am Geriatrics Soc"},{"key":"10.1016\/j.jacc.2007.12.024_bib34","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1161\/01.CIR.1.2.187","article-title":"Life stress and cardiovascular disease","volume":"1","author":"Wolff","year":"1950","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.12.024_bib35","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1161\/01.CIR.97.18.1837","article-title":"Prediction of coronary heart disease using risk factor categories","volume":"97","author":"Wilson","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2007.12.024_bib36","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1360-0443.2005.01292.x","article-title":"Financial stress, smoking cessation and relapse: results from a prospective study of an Australian national sample","volume":"101","author":"Siahpush","year":"2006","journal-title":"Addiction"},{"key":"10.1016\/j.jacc.2007.12.024_bib37","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD002902.pub2","article-title":"Psychological interventions for coronary heart disease","volume":"2","author":"Rees","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jacc.2007.12.024_bib38","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1001\/jama.293.13.1626","article-title":"Effects of exercise and stress management training on markers of cardiovascular risk in patients with ischemic heart disease: a randomized controlled trial","volume":"293","author":"Blumenthal","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2007.12.024_bib39","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/S0002-9149(02)02726-1","article-title":"An unanticipated effect of meditation on cardiovascular pharmacology and physiology","volume":"90","author":"Dimsdale","year":"2002","journal-title":"Am J Cardiol"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109708002581?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109708002581?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,30]],"date-time":"2018-12-30T14:53:37Z","timestamp":1546181617000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109708002581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":39,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["S0735109708002581"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2007.12.024","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2008,4]]}}}