{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:52:05Z","timestamp":1790319125067,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":1779,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1016\/j.jacc.2008.04.067","type":"journal-article","created":{"date-parts":[[2008,9,10]],"date-time":"2008-09-10T07:23:03Z","timestamp":1221031383000},"page":"979-985","source":"Crossref","is-referenced-by-count":136,"title":["Obesity and Age of First Non\u2013ST-Segment Elevation Myocardial Infarction"],"prefix":"10.1016","volume":"52","author":[{"given":"Mohan C.","family":"Madala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry A.","family":"Franklin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita Y.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron D.","family":"Berman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew T.","family":"Roe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric D.","family":"Peterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Magnus","family":"Ohman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Sidney C.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Brian","family":"Gibler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"McCullough","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2008.04.067_bib1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.amjmed.2006.06.004","article-title":"Increasing trends in incidence of overweight and obesity over 5 decades","volume":"120","author":"Parikh","year":"2007","journal-title":"Am J Med"},{"key":"10.1016\/j.jacc.2008.04.067_bib2","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1001\/jama.295.13.1549","article-title":"Prevalence of overweight and obesity in the United States, 1999\u20132004","volume":"95","author":"Ogden","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2008.04.067_bib3","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.puhe.2007.01.006","article-title":"Increases in morbid obesity in the USA: 2000\u20132005","volume":"121","author":"Sturm","year":"2007","journal-title":"Public Health"},{"issue":"Suppl","key":"10.1016\/j.jacc.2008.04.067_bib4","doi-asserted-by":"crossref","first-page":"68B","DOI":"10.1016\/j.amjcard.2006.11.007","article-title":"Weight management for type 2 diabetes mellitus: global cardiovascular risk reduction","volume":"99","author":"Lee","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2008.04.067_bib5","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1001\/jama.289.1.76","article-title":"Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001","volume":"289","author":"Mokdad","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2008.04.067_bib6","doi-asserted-by":"crossref","first-page":"3Q","DOI":"10.1016\/j.amjcard.2006.09.020","article-title":"Atherosclerosis: disease biology affecting the coronary vasculature","volume":"98","author":"Libby","year":"2006","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2008.04.067_bib7","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1111\/j.1538-7836.2007.02643.x","article-title":"Inter-relationships of interleukin-6, cardiovascular risk factors and the metabolic syndrome among older men","volume":"5","author":"Wannamethee","year":"2007","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jacc.2008.04.067_bib8","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1080\/07853890500401234","article-title":"The metabolic syndrome and cardiovascular disease","volume":"38","author":"Bonora","year":"2006","journal-title":"Ann Med"},{"key":"10.1016\/j.jacc.2008.04.067_bib9","first-page":"9","article-title":"The relationship among risk factor clustering, abdominal obesity, and residual risk for cardiovascular events","volume":"8","author":"Ryan","year":"2007","journal-title":"Rev Card Med"},{"key":"10.1016\/j.jacc.2008.04.067_bib10","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1111\/j.1553-2712.2002.tb01569.x","article-title":"Improving the care of patients with non\u2013ST-elevation acute coronary syndromes in the emergency department: the CRUSADE initiative","volume":"9","author":"Hoekstra","year":"2002","journal-title":"Acad Emerg Med"},{"key":"10.1016\/j.jacc.2008.04.067_bib11","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/biomet\/73.1.13","article-title":"Longitudinal data analysis using generalized linear models","volume":"73","author":"Liang","year":"1986","journal-title":"Biometrika"},{"key":"10.1016\/j.jacc.2008.04.067_bib12","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.ahj.2005.09.024","volume":"152","author":"Diercks","year":"2006","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacc.2008.04.067_bib13","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1002\/clc.4960240804","article-title":"Obesity is associated with premature occurrence of acute myocardial infarction","volume":"24","author":"Suwaidi","year":"2001","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.jacc.2008.04.067_bib14","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.amjcard.2006.11.038","article-title":"Impact of body mass index on outcomes after percutaneous coronary intervention in patients with acute myocardial infarction","volume":"99","author":"Mehta","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2008.04.067_bib15","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1586\/14779072.3.4.761","article-title":"Optimal diabetes management during medical weight loss for cardiovascular risk reduction","volume":"3","author":"Nori Janosz","year":"2005","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"10.1016\/j.jacc.2008.04.067_bib16","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.ahj.2006.12.018","article-title":"Documented traditional cardiovascular risk factors and mortality in non\u2013ST-segment elevation myocardial infarction","volume":"153","author":"Roe","year":"2007","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacc.2008.04.067_bib17","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1001\/archinte.165.18.2063","article-title":"High attributable risk of elevated C-reactive protein level to conventional coronary heart disease risk factors: the Third National Health and Nutrition Examination Survey","volume":"165","author":"Miller","year":"2005","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jacc.2008.04.067_bib18","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1161\/CIRCULATIONAHA.106.171016","article-title":"AHA scientific statement","volume":"113","author":"Poirier","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2008.04.067_bib19","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.amepre.2004.02.001","article-title":"Attempting to lose weight: specific practices among U.S. adults","volume":"26","author":"Kruger","year":"2004","journal-title":"Am J Prev Med"},{"key":"10.1016\/j.jacc.2008.04.067_bib20","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1056\/NEJM199910073411501","article-title":"Body-mass index and mortality in a prospective cohort of U.S. adults","volume":"341","author":"Calle","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2008.04.067_bib21","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1001\/archinte.164.21.2326","article-title":"Body mass index and total and cardiovascular mortality in men with a history of cardiovascular disease","volume":"164","author":"Widlansky","year":"2004","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jacc.2008.04.067_bib22","doi-asserted-by":"crossref","first-page":"749","DOI":"10.7326\/0003-4819-119-7_Part_2-199310011-00024","article-title":"Body weight change, all-cause mortality, and cause-specific mortality in the multiple risk factor intervention trial","volume":"119","author":"Blair","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jacc.2008.04.067_bib23","doi-asserted-by":"crossref","first-page":"758","DOI":"10.7326\/0003-4819-119-7_Part_2-199310011-00025","article-title":"Benefits and adverse effects of weight loss: observations from the Framingham Study","volume":"119","author":"Higgins","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jacc.2008.04.067_bib24","doi-asserted-by":"crossref","first-page":"2755","DOI":"10.1093\/eurheartj\/ehl182","article-title":"Weight-change as a prognostic marker in 12 550 patients following acute myocardial infarction or with stable coronary artery disease","volume":"27","author":"Kennedy","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2008.04.067_bib25","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1016\/S0140-6736(05)67663-5","article-title":"Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study","volume":"366","author":"Yusuf","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2008.04.067_bib26","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.amjcard.2006.08.017","article-title":"Reduction in predicted coronary heart disease risk after substantial weight reduction after bariatric surgery","volume":"99","author":"Vogel","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2008.04.067_bib27","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1161\/01.CIR.0000095270.85646.E8","article-title":"Body mass index: a risk factor for unstable angina and myocardial infarction in patients with angiographically confirmed coronary artery disease","volume":"108","author":"Wolk","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2008.04.067_bib28","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/sj.ijo.0802831","article-title":"Recognition, diagnosis and management of obesity after myocardial infarction","volume":"29","author":"Lopez-Jimenez","year":"2005","journal-title":"Int J Obes (Lond)"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109708022055?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109708022055?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,25]],"date-time":"2018-12-25T19:54:33Z","timestamp":1545767673000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109708022055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":28,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["S0735109708022055"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2008.04.067","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2008,9]]}}}