{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T13:27:03Z","timestamp":1782912423945,"version":"3.54.5"},"reference-count":39,"publisher":"Elsevier BV","issue":"21","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":1718,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1016\/j.jacc.2008.07.061","type":"journal-article","created":{"date-parts":[[2008,11,18]],"date-time":"2008-11-18T11:57:23Z","timestamp":1227009443000},"page":"1718-1723","source":"Crossref","is-referenced-by-count":72,"title":["Implantable Cardioverter-Defibrillator Therapy for Primary Prevention of Sudden Death After Alcohol Septal Ablation of Hypertrophic Cardiomyopathy"],"prefix":"10.1016","volume":"52","author":[{"given":"Frank A.","family":"Cuoco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"William H.","family":"Spencer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerian L.","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher D.","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherif","family":"Nagueh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Lacy","family":"Sturdivant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert B.","family":"Leman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Marcus","family":"Wharton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Gold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2008.07.061_bib1","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1016\/S0735-1097(03)00941-0","volume":"42","author":"Maron","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2008.07.061_bib2","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1161\/01.CIR.37.5.759","article-title":"Idiopathic hypertrophic subaortic stenosis: clinical analysis of 126 patients with emphasis on the natural history","volume":"37","author":"Frank","year":"1968","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2008.07.061_bib3","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1161\/01.CIR.102.8.858","article-title":"Epidemiology of hypertrophic cardiomyopathy-related death: revisited in a large non-referral based patient population","volume":"102","author":"Maron","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2008.07.061_bib4","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1056\/NEJM199703133361107","article-title":"The management of hypertrophic cardiomyopathy","volume":"336","author":"Spirito","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2008.07.061_bib5","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0140-6736(97)01282-8","article-title":"Hypertrophic cardiomyopathy","volume":"350","author":"Maron","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2008.07.061_bib6","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1001\/jama.287.10.1308","article-title":"Hypertrophic cardiomyopathy: a systematic review","volume":"287","author":"Maron","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2008.07.061_bib7","first-page":"V10","article-title":"Results of surgery for hypertrophic obstructive cardiomyopathy","volume":"76","author":"Williams","year":"1987","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2008.07.061_bib8","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/S0022-5223(19)34512-X","article-title":"The outcome of surgical treatment of hypertrophic obstructive cardiomyopathy: experience over 15 years","volume":"97","author":"Mohr","year":"1990","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jacc.2008.07.061_bib9","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S0735-1097(10)80176-7","article-title":"Long term follow-up of medical versus surgical therapy for hypertrophic cardiomyopathy: a retrospective study","volume":"17","author":"Seiler","year":"1991","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2008.07.061_bib10","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1161\/01.CIR.90.4.1781","article-title":"Hypertrophic obstructive cardiomyopathy: initial results and long term follow-up after Morrow septal myectomy","volume":"90","author":"ten Berg","year":"1994","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2008.07.061_bib11","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0022-5223(05)80026-1","article-title":"Surgical management of hypertrophic obstructive cardiomyopathy: early and late results","volume":"110","author":"Heric","year":"1995","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jacc.2008.07.061_bib12","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.jacc.2005.02.090","article-title":"Long-term effects of surgical septal myectomy on survival in patients with obstructive hypertrophic cardiomyopathy","volume":"46","author":"Ommen","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2008.07.061_bib13","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0140-6736(95)91267-3","article-title":"Non-surgical myocardial reduction for hypertrophic obstructive cardiomyopathy","volume":"346","author":"Sigwart","year":"1995","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2008.07.061_bib14","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1161\/01.CIR.95.8.2075","article-title":"Non-surgical septal reduction for hypertrophic obstructive cardiomyopathy: outcome in the first series of patients","volume":"95","author":"Knight","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2008.07.061_bib15","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/S0735-1097(97)00508-1","article-title":"Percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy: acute results and 3-month follow-up in 25 patients","volume":"31","author":"Seggewiss","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2008.07.061_bib16","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1161\/01.CIR.98.17.1750","article-title":"Echocardiography guided ethanol septal reduction for hypertrophic obstructive cardiomyopathy","volume":"98","author":"Lakkis","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2008.07.061_bib17","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1016\/S0735-1097(01)01614-X","article-title":"Comparison of ethanol septal reduction therapy with surgical myectomy for the treatment of hypertrophic obstructive cardiomyopathy","volume":"38","author":"Nagueh","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2008.07.061_bib18","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/S0735-1097(00)00767-1","article-title":"Nonsurgical septal reduction therapy for hypertrophic obstructive cardiomyopathy: one-year follow-up","volume":"36","author":"Lakkis","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2008.07.061_bib19","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S0140-6736(99)00444-4","article-title":"Role of alcohol septal ablation in the treatment of obstructive hypertrophic cardiomyopathy","volume":"355","author":"Maron","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2008.07.061_bib20","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1161\/01.CIR.103.11.1492","article-title":"Regression of left ventricular hypertrophy after nonsurgical septal reduction therapy for hypertrophic obstructive cardiomyopathy","volume":"103","author":"Mazur","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2008.07.061_bib21","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1053\/euhj.1999.1520","article-title":"Acute and long-term results after transcoronary ablation of septal hypertrophy (TASH): catheter interventional treatment for hypertrophic obstructive cardiomyopathy","volume":"20","author":"Gietzen","year":"1999","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2008.07.061_bib22","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1540-8159.2005.09327.x","article-title":"Transcoronary ablation of septal hypertrophy does not alter ICD intervention rates in high risk patients with hypertrophic obstructive cardiomyopathy","volume":"28","author":"Lawrenz","year":"2005","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.jacc.2008.07.061_bib23","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1136\/hrt.80.3.257","article-title":"Electrocardiographic changes after alcohol septal ablation in hypertrophic obstructive cardiomyopathy","volume":"80","author":"Kazmierczak","year":"1998","journal-title":"Heart"},{"key":"10.1016\/j.jacc.2008.07.061_bib24","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/00000441-200409000-00011","article-title":"Monomorphic ventricular tachycardia: a late complication of percutaneous alcohol septal ablation for hypertrophic cardiomyopathy","volume":"328","author":"McGregor","year":"2004","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.jacc.2008.07.061_bib25","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1056\/NEJM200410283511824","article-title":"Ventricular tachycardia complicating alcohol septal ablation","volume":"351","author":"Boltwood","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2008.07.061_bib26","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1111\/j.1540-8159.2005.00278.x","article-title":"Sustained ventricular tachycardia following alcohol septal ablation for hypertrophic obstructive cardiomyopathy","volume":"28","author":"Simon","year":"2005","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.jacc.2008.07.061_bib27","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1001\/jama.298.4.405","article-title":"Implantable cardioverter-defibrillators and prevention of sudden cardiac death in hypertrophic cardiomyopathy","volume":"298","author":"Maron","year":"2007","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2008.07.061_bib28","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1056\/NEJM200002103420601","article-title":"Efficacy of implantable cardioverter-defibrillators for the prevention of sudden death in patients with hypertrophic cardiomyopathy","volume":"342","author":"Maron","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2008.07.061_bib29","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.jacc.2004.11.043","article-title":"Spectrum and prognostic significance of arrhythmias on ambulatory Holter electrocardiogram in hypertrophic cardiomyopathy","volume":"45","author":"Adabag","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2008.07.061_bib30","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1056\/NEJM198703263161305","article-title":"Hypertrophic cardiomyopathy: interrelation of clinical manifestations, pathophysiology, and therapy","volume":"316","author":"Maron","year":"1987","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2008.07.061_bib31","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1053\/euhj.2000.2238","article-title":"Hypertrophic cardiomyopathy and sudden death: new perspectives on risk stratification and prevention with the implantable cardioverter-defibrillator","volume":"21","author":"Maron","year":"2000","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2008.07.061_bib32","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1093\/eurheartj\/ehl041","article-title":"Left ventricular outflow tract obstruction and sudden death risk in patients with hypertrophic cardiomyopathy","volume":"27","author":"Elliot","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2008.07.061_bib33","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jacc.2003.08.031","article-title":"Myocardial infarction after percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy: evaluation by contrast-enhanced magnetic resonance imaging","volume":"43","author":"van Dockum","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2008.07.061_bib34","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S1071-3581(97)90029-5","article-title":"Relationship of scar and ischemia to the results of programmed electrophysiological stimulation in patients with coronary artery disease","volume":"4","author":"Gradel","year":"1997","journal-title":"J Nucl Cardiol"},{"key":"10.1016\/j.jacc.2008.07.061_bib35","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1056\/NEJM200006153422403","article-title":"Magnitude of left ventricular hypertrophy and risk of sudden death in hypertrophic cardiomyopathy","volume":"342","author":"Spirito","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2008.07.061_bib36","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/clc.4960280305","article-title":"A prospective follow-up of alcohol septal ablation for symptomatic hypertrophic obstructive cardiomyopathy\u2014the Baylor experience (1996\u20132002)","volume":"28","author":"Fernandes","year":"2005","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.jacc.2008.07.061_bib37","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1161\/01.CIR.0000117089.99918.5A","article-title":"Predictors of outcome after alcohol septal ablation therapy in patients with hypertrophic obstructive cardiomyopathy","volume":"109","author":"Chang","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2008.07.061_bib38","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.1093\/eurheartj\/ehm117","article-title":"Surgical septal myectomy decreases the risk for appropriate implantable cardioverter defibrillator discharge in obstructive hypertrophic cardiomyopathy","volume":"28","author":"McLeod","year":"2007","journal-title":"Eur Hear J"},{"key":"10.1016\/j.jacc.2008.07.061_bib39","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1056\/NEJMoa021332","article-title":"Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy","volume":"348","author":"Maron","year":"2003","journal-title":"N Engl J Med"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109708029604?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109708029604?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,10]],"date-time":"2020-05-10T10:18:37Z","timestamp":1589105917000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109708029604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":39,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["S0735109708029604"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2008.07.061","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2008,11]]}}}