{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:45:22Z","timestamp":1788871522668,"version":"build-2803163510"},"reference-count":39,"publisher":"Elsevier BV","issue":"15","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T00:00:00Z","timestamp":1397606400000},"content-version":"vor","delay-in-days":380,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"crossref","award":["1R01DK078106-01"],"award-info":[{"award-number":["1R01DK078106-01"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Abbott"},{"name":"Abbott"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1016\/j.jacc.2012.11.071","type":"journal-article","created":{"date-parts":[[2013,4,9]],"date-time":"2013-04-09T03:35:17Z","timestamp":1365478517000},"page":"1626-1633","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Outcomes Associated With Microalbuminuria"],"prefix":"10.1016","volume":"61","author":[{"given":"Csaba P.","family":"Kovesdy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan H.","family":"Lott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Ling","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra M.","family":"Malakauskas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennie Z.","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miklos Z.","family":"Molnar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamyar","family":"Kalantar-Zadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2012.11.071_bib1","first-page":"e46","article-title":"Heart disease and stroke statistics\u20142010 update: a report from the American Heart Association","volume":"121","author":"Lloyd-Jones","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2012.11.071_bib2","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1161\/01.CIR.0000031732.78052.81","article-title":"Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population","volume":"106","author":"Hillege","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2012.11.071_bib3","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1161\/01.CIR.0000133312.96477.48","article-title":"Very low levels of microalbuminuria are associated with increased risk of coronary heart disease and death independently of renal function, hypertension, and diabetes","volume":"110","author":"Klausen","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2012.11.071_bib4","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/S0272-6386(03)00742-X","article-title":"Microalbuminuria and all-cause mortality in 2,089 apparently healthy individuals: a 4.4-year follow-up study","volume":"42","author":"Romundstad","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.jacc.2012.11.071_bib5","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1093\/ije\/dyh008","article-title":"Microalbuminuria independently predicts all-cause and cardiovascular mortality in a British population: the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study","volume":"33","author":"Yuyun","year":"2004","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.jacc.2012.11.071_bib6","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1001\/jama.286.4.421","article-title":"Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals","volume":"286","author":"Gerstein","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2012.11.071_bib7","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1016\/S0140-6736(10)60674-5","article-title":"Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis","volume":"375","author":"Matsushita","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2012.11.071_bib8","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1038\/ki.2010.550","article-title":"Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease","volume":"79","author":"Astor","year":"2011","journal-title":"Kidney Int"},{"key":"10.1016\/j.jacc.2012.11.071_bib9","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.2215\/CJN.09741110","article-title":"Associations among estimated glomerular filtration rate, proteinuria, and adverse cardiovascular outcomes","volume":"6","author":"Bello","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.jacc.2012.11.071_bib10","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/ki.2010.531","article-title":"Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes","volume":"80","author":"Gansevoort","year":"2011","journal-title":"Kidney Int"},{"key":"10.1016\/j.jacc.2012.11.071_bib11","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1001\/jama.2010.39","article-title":"Relation between kidney function, proteinuria, and adverse outcomes","volume":"303","author":"Hemmelgarn","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2012.11.071_bib12","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1001\/archinternmed.2010.129","article-title":"Prognostic implications of the urinary albumin to creatinine ratio in veterans of different ages with diabetes","volume":"170","author":"O'Hare","year":"2010","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jacc.2012.11.071_bib13","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1053\/j.ajkd.2010.05.017","article-title":"Kidney function, albuminuria, and all-cause mortality in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) study","volume":"56","author":"Warnock","year":"2010","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.jacc.2012.11.071_bib14","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1681\/ASN.2006010097","article-title":"Screening, monitoring, and treatment of albuminuria: public health perspectives","volume":"17","author":"de Jong","year":"2006","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.jacc.2012.11.071_bib15","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1161\/CIRCULATIONAHA.105.538132","article-title":"Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study","volume":"112","author":"Arnlov","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2012.11.071_bib16","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1161\/CIRCULATIONAHA.111.065391","article-title":"Hyponatremia, hypernatremia, and mortality in patients with chronic kidney disease with and without congestive heart failure","volume":"125","author":"Kovesdy","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2012.11.071_bib17","series-title":"VIReC Research User Guide. Veterans Health Administration Decision Support System Clinical National Data Extracts","year":"2009"},{"key":"10.1016\/j.jacc.2012.11.071_bib18","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jacc.2012.11.071_bib19","series-title":"US Department of Veterans Affairs, VA Information Resource Center Data Quality Update: Race","year":"2009"},{"key":"10.1016\/j.jacc.2012.11.071_bib20","series-title":"VIReC Research User Guide. VHA Medical SAS Inpatient Datasets FY2006","year":"2007"},{"key":"10.1016\/j.jacc.2012.11.071_bib21","series-title":"VIReC Research User Guide. VHA Medical SAS Outpatient Datasets FY2006","year":"2007"},{"key":"10.1016\/j.jacc.2012.11.071_bib22","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/0895-4356(92)90133-8","article-title":"Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases","volume":"45","author":"Deyo","year":"1992","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.jacc.2012.11.071_bib23","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1080\/00949658808811085","article-title":"Imputation using Markov chains","volume":"30","author":"Li","year":"1988","journal-title":"J Stat Comput Simul"},{"key":"10.1016\/j.jacc.2012.11.071_bib24","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1080\/01621459.1987.10478458","article-title":"The calculation of posterior distributions by data augmentation","volume":"82","author":"Tanner","year":"1987","journal-title":"J Am Stat Assoc"},{"key":"10.1016\/j.jacc.2012.11.071_bib25","series-title":"VIReC Technical Report 2. VA-NDI Mortality Data Merge Project. Edward Hines Jr. VA Hospital","author":"Arnold","year":"2006"},{"key":"10.1016\/j.jacc.2012.11.071_bib26","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.2215\/CJN.00080106","article-title":"Cohort studies: marching forward","volume":"1","author":"Thadhani","year":"2006","journal-title":"Clin J Am Soc Nephrol"},{"issue":"Suppl","key":"10.1016\/j.jacc.2012.11.071_bib27","first-page":"1","article-title":"K\/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification","volume":"39","year":"2002","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.jacc.2012.11.071_bib28","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/BF00285287","article-title":"Albuminuria reflects widespread vascular damage","volume":"32","author":"Deckert","year":"1989","journal-title":"Diabetologia"},{"key":"10.1016\/j.jacc.2012.11.071_bib29","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1056\/NEJMra020676","article-title":"Renal dysfunction complicating the treatment of hypertension","volume":"347","author":"Palmer","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2012.11.071_bib30","doi-asserted-by":"crossref","first-page":"II29","DOI":"10.1161\/01.HYP.7.6_Pt_2.II29","article-title":"Renal histopathology in hypertensive diabetic patients","volume":"7","author":"Ditscherlein","year":"1985","journal-title":"Hypertension"},{"key":"10.1016\/j.jacc.2012.11.071_bib31","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1172\/JCI115264","article-title":"Impaired autoregulation of glomerular capillary hydrostatic pressure in the rat remnant nephron","volume":"88","author":"Pelayo","year":"1991","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jacc.2012.11.071_bib32","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1161\/HYPERTENSIONAHA.109.133777","article-title":"Protective importance of the myogenic response in the renal circulation","volume":"54","author":"Bidani","year":"2009","journal-title":"Hypertension"},{"key":"10.1016\/j.jacc.2012.11.071_bib33","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1056\/NEJMra064398","article-title":"Normotensive ischemic acute renal failure","volume":"357","author":"Abuelo","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jacc.2012.11.071_bib34","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1161\/01.HYP.0000154895.18269.67","article-title":"Reverse epidemiology of hypertension and cardiovascular death in the hemodialysis population: the 58th annual fall conference and scientific sessions","volume":"45","author":"Kalantar-Zadeh","year":"2005","journal-title":"Hypertension"},{"issue":"Suppl","key":"10.1016\/j.jacc.2012.11.071_bib35","first-page":"173","article-title":"Is hypertension a mortality risk factor in dialysis?","volume":"55","author":"Duranti","year":"1996","journal-title":"Kidney Int"},{"key":"10.1016\/j.jacc.2012.11.071_bib36","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0272-6386(99)70188-5","article-title":"Predialysis blood pressure and mortality risk in a national sample of maintenance hemodialysis patients","volume":"33","author":"Port","year":"1999","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.jacc.2012.11.071_bib37","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1046\/j.1523-1755.1998.00005.x","article-title":"\u201cU\u201d curve association of blood pressure and mortality in hemodialysis patients","volume":"54","author":"Zager","year":"1998","journal-title":"Kidney Int"},{"key":"10.1016\/j.jacc.2012.11.071_bib38","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1093\/ndt\/gfk057","article-title":"Association of low blood pressure with increased mortality in patients with moderate to severe chronic kidney disease","volume":"21","author":"Kovesdy","year":"2006","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.jacc.2012.11.071_bib39","doi-asserted-by":"crossref","first-page":"830","DOI":"10.2215\/CJN.06201208","article-title":"Blood pressure components and the risk for end-stage renal disease and death in chronic kidney disease","volume":"4","author":"Agarwal","year":"2009","journal-title":"Clin J Am Soc Nephrol"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109713005895?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109713005895?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T12:57:49Z","timestamp":1760014669000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109713005895"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":39,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["S0735109713005895"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2012.11.071","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2013,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outcomes Associated With Microalbuminuria","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2012.11.071","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}