{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T21:04:10Z","timestamp":1769115850265,"version":"3.49.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,7,9]],"date-time":"2014-07-09T00:00:00Z","timestamp":1404864000000},"content-version":"vor","delay-in-days":373,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1016\/j.jacc.2013.02.089","type":"journal-article","created":{"date-parts":[[2013,5,9]],"date-time":"2013-05-09T02:16:02Z","timestamp":1368065762000},"page":"96-102","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":220,"title":["Percutaneous Left Atrial Appendage Closure With the AMPLATZER Cardiac Plug Device in Patients With Nonvalvular Atrial Fibrillation and Contraindications to Anticoagulation Therapy"],"prefix":"10.1016","volume":"62","author":[{"given":"Marina","family":"Urena","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep","family":"Rod\u00e9s-Cabau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Freixa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"Saw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John G.","family":"Webb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e9lanie","family":"Freeman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Horlick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Osten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Francois","family":"Marquis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Champagne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00e9da","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2013.02.089_bib1","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1001\/archinte.167.13.1414","article-title":"Bleeding complications with warfarin use: a prevalent adverse effect resulting in regulatory action","volume":"167","author":"Wysowski","year":"2007","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jacc.2013.02.089_bib2","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.amjcard.2005.09.086","article-title":"Patterns and predictors of warfarin use in patients with new-onset atrial fibrillation from the FRACTAL Registry","volume":"97","author":"Reynolds","year":"2006","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2013.02.089_bib3","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/S0140-6736(09)61343-X","article-title":"Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial","volume":"374","author":"Holmes","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2013.02.089_bib4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jacc.2005.03.042","article-title":"Percutaneous left atrial appendage transcatheter occlusion (PLAATO system) to prevent stroke in high-risk patients with non-rheumatic atrial fibrillation: results from the international multi-center feasibility trials","volume":"46","author":"Ostermayer","year":"2005","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2013.02.089_bib5","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.jcin.2009.05.005","article-title":"Percutaneous left atrial appendage occlusion for patients in atrial fibrillation suboptimal for warfarin therapy: 5-year results of the PLAATO (Percutaneous Left Atrial Appendage Transcatheter Occlusion) Study","volume":"2","author":"Block","year":"2009","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2013.02.089_bib6","first-page":"446","article-title":"Percutaneous left atrial appendage transcatheter occlusion (PLAATO) for stroke prevention in atrial fibrillation: 2-year outcomes","volume":"21","author":"Park","year":"2009","journal-title":"J\u00a0Invasive Cardiol"},{"key":"10.1016\/j.jacc.2013.02.089_bib7","first-page":"217","article-title":"Percutaneous closure of left atrial appendage to prevent embolic events in high-risk patients with chronic atrial fibrillation","volume":"74","author":"Ussia","year":"2009","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2013.02.089_bib8","doi-asserted-by":"crossref","first-page":"220","DOI":"10.4244\/EIJV6I2A35","article-title":"PLAATO (Percutaneous Left Atrial Appendage Transcatheter Occlusion) for prevention of cardioembolic stroke in non-anticoagulation eligible atrial fibrillation patients: results from the European PLAATO study","volume":"6","author":"Bayard","year":"2010","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jacc.2013.02.089_bib9","first-page":"794","article-title":"Left atrial appendage closure with Amplatzer cardiac plug for stroke prevention in atrial fibrillation: Initial Asia-Pacific experience","volume":"79","author":"Lam","year":"2011","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2013.02.089_bib10","first-page":"700","article-title":"Left atrial appendage closure with Amplatzer cardiac plug in atrial fibrillation: initial European experience","volume":"77","author":"Park","year":"2011","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2013.02.089_bib11","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1161\/01.CIR.0000145172.55640.93","article-title":"Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin","volume":"110","author":"Gage","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2013.02.089_bib12","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1161\/STROKEAHA.110.590257","article-title":"Identifying patients at high risk for stroke despite anticoagulation: a comparison of contemporary stroke risk stratification schemes in an anticoagulated atrial fibrillation cohort","volume":"41","author":"Lip","year":"2010","journal-title":"Stroke"},{"key":"10.1016\/j.jacc.2013.02.089_bib13","first-page":"186","article-title":"Transcatheter closure of the left atrial appendage: initial experience with the Amplatzer cardiac plug device","volume":"76","author":"Rodes-Cabau","year":"2010","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2013.02.089_bib14","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.jacc.2010.12.005","article-title":"Standardized endpoint definitions for Transcatheter Aortic Valve Implantation clinical trials: a consensus report from the Valve Academic Research Consortium","volume":"57","author":"Leon","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2013.02.089_bib15","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.jacc.2011.11.028","volume":"59","author":"Viles-Gonzalez","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2013.02.089_bib16","first-page":"970","article-title":"Thrombus formation after left atrial appendage exclusion using an Amplatzer cardiac plug device","volume":"78","author":"Cruz-Gonzalez","year":"2011","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2013.02.089_bib17","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1016\/j.jacc.2013.03.035","article-title":"Left atrial appendage closure with the Watchman device in patients with a contraindication for oral anticoagulation: the ASAP study (ASA Plavix Feasibility Study With Watchman Left Atrial Appendage Closure Technology)","volume":"61","author":"Reddy","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2013.02.089_bib18","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.jacc.2012.06.046","article-title":"Percutaneous left atrial appendage suture ligation using the LARIAT device in patients with atrial fibrillation: initial clinical experience","volume":"62","author":"Bartus","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2013.02.089_bib19","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s10840-011-9613-x","article-title":"Incomplete occlusion of the LAA with the PLAATO device is not associated with increased risk of stroke","volume":"33","author":"Viles-Gonzalez","year":"2012","journal-title":"J\u00a0Interv Card Electrophysiol"},{"key":"10.1016\/j.jacc.2013.02.089_bib20","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.1540-8167.2011.02216.x","article-title":"Intraprocedural and long-term incomplete occlusion of the left atrial appendage following placement of the WATCHMAN device: a single center experience","volume":"23","author":"Bai","year":"2012","journal-title":"J\u00a0Cardiovasc Electrophysiol"},{"key":"10.1016\/j.jacc.2013.02.089_bib21","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1093\/eurheartj\/ehr488","article-title":"Evaluation of risk stratification schemes for ischaemic stroke and bleeding in 182 678 patients with atrial fibrillation: the Swedish Atrial Fibrillation cohort study","volume":"33","author":"Friberg","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2013.02.089_bib22","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1378\/chest.10-0134","article-title":"A\u00a0novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey","volume":"138","author":"Pisters","year":"2010","journal-title":"Chest"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073510971301797X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073510971301797X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T12:59:58Z","timestamp":1760014798000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073510971301797X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S073510971301797X"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2013.02.089","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Percutaneous Left Atrial Appendage Closure With the AMPLATZER Cardiac Plug Device in Patients With Nonvalvular Atrial Fibrillation and Contraindications to Anticoagulation Therapy","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2013.02.089","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}