{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T22:34:19Z","timestamp":1771022059894,"version":"3.50.1"},"reference-count":42,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,7,8]],"date-time":"2015-07-08T00:00:00Z","timestamp":1436313600000},"content-version":"vor","delay-in-days":372,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1016\/j.jacc.2014.04.022","type":"journal-article","created":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T15:45:30Z","timestamp":1404315930000},"page":"16-24","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":104,"title":["Stent Thrombosis in New-Generation Drug-Eluting Stents in Patients With STEMI Undergoing Primary PCI"],"prefix":"10.1016","volume":"64","author":[{"given":"Giovanna","family":"Sarno","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Lagerqvist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan","family":"Nilsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ole","family":"Frobert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina","family":"Hambraeus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Varenhorst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf J.","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"T\u00f6dt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"G\u00f6tberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan K.","family":"James","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2014.04.022_bib1","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1056\/NEJMoa012843","article-title":"A\u00a0randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization","volume":"346","author":"Morice","year":"2002","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2014.04.022_bib2","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.jacc.2007.06.029","article-title":"Long-term clinical outcomes with sirolimus-eluting coronary stents: five-year results of the RAVEL trial","volume":"50","author":"Morice","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2014.04.022_bib3","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.jacc.2008.09.067","article-title":"Outcome of drug-eluting versus bare-metal stenting used according to on- and off-label criteria","volume":"53","author":"Carlsson","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2014.04.022_bib4","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.jcin.2009.09.014","article-title":"Clinical outcomes after unrestricted implantation of everolimus-eluting stents","volume":"2","author":"Latib","year":"2009","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2014.04.022_bib5","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/j.jcin.2010.08.003","volume":"3","author":"Simsek","year":"2010","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2014.04.022_bib6","first-page":"336","volume":"23","author":"Simsek","year":"2011","journal-title":"J\u00a0Invasive Cardiol"},{"key":"10.1016\/j.jacc.2014.04.022_bib7","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1160\/TH10-08-0528","article-title":"The relationship between platelet reactivity and\u00a0infarct-related artery patency in patients presenting with a ST-elevation myocardial infarction","volume":"106","author":"Breet","year":"2011","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jacc.2014.04.022_bib8","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1016\/j.jacc.2005.12.085","article-title":"Value of platelet reactivity in predicting response to treatment and clinical outcome in patients undergoing primary coronary intervention: insights into the STRATEGY Study","volume":"48","author":"Campo","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2014.04.022_bib9","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1161\/CIRCULATIONAHA.107.762047","article-title":"Delayed arterial healing and increased late stent thrombosis at culprit sites after drug-eluting stent placement for acute myocardial infarction patients: an autopsy study","volume":"118","author":"Nakazawa","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2014.04.022_bib10","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1161\/CIRCULATIONAHA.106.675934","article-title":"Drug-eluting stent and coronary thrombosis: biological mechanisms and clinical implications","volume":"115","author":"Luscher","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2014.04.022_bib11","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.1161\/CIRCULATIONAHA.106.618066","article-title":"Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: results from the PREMIER registry","volume":"113","author":"Spertus","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2014.04.022_bib12","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.amjcard.2006.11.070","article-title":"Comparison of three-year clinical outcome of sirolimus- and paclitaxel-eluting stents versus bare metal stents in patients with ST-segment elevation myocardial infarction (from the RESEARCH and T-SEARCH Registries)","volume":"99","author":"Daemen","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2014.04.022_bib13","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.jacc.2010.05.009","article-title":"Long-term outcome after drug-eluting versus bare-metal stent implantation in patients with ST-segment elevation myocardial infarction: 3-year follow-up of the randomized DEDICATION (Drug Elution and Distal Protection in Acute Myocardial Infarction) Trial","volume":"56","author":"Kaltoft","year":"2010","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2014.04.022_bib14","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1016\/S0140-6736(12)61223-9","article-title":"Everolimus-eluting stent versus bare-metal stent in ST-segment elevation myocardial infarction (EXAMINATION): 1 year results of a randomised controlled trial","volume":"380","author":"Sabate","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2014.04.022_bib15","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1001\/jama.2012.10065","article-title":"Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial","volume":"308","author":"Raber","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2014.04.022_bib16","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jcin.2010.10.007","article-title":"Four-year follow-up of TYPHOON (trial to assess the use of the CYPHer sirolimus-eluting coronary stent in acute myocardial infarction treated with BallOON angioplasty)","volume":"4","author":"Spaulding","year":"2011","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2014.04.022_bib17","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1056\/NEJMoa066633","article-title":"A\u00a0pooled analysis of data comparing sirolimus-eluting stents with bare-metal stents","volume":"356","author":"Spaulding","year":"2007","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2014.04.022_bib18","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.jacc.2007.09.056","article-title":"Sirolimus-eluting stents versus bare-metal stents in patients with ST-segment elevation myocardial infarction: 9-month angiographic and intravascular ultrasound results and 12-month clinical outcome results from the MISSION! Intervention Study","volume":"51","author":"van der Hoeven","year":"2008","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2014.04.022_bib19","doi-asserted-by":"crossref","first-page":"e43","DOI":"10.1016\/j.ahj.2009.03.016","article-title":"Benefits of drug-eluting stents as compared to bare metal stent in ST-segment elevation myocardial infarction: four year results of the PaclitAxel or Sirolimus-Eluting stent vs bare metal stent in primary angiOplasty (PASEO) randomized trial","volume":"158","author":"Di Lorenzo","year":"2009","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacc.2014.04.022_bib20","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1161\/CIRCULATIONAHA.107.758698","article-title":"Drug-eluting versus bare metal stents in patients with\u00a0ST-segment-elevation myocardial infarction: eight-month follow-up in the Drug Elution and Distal Protection in Acute Myocardial Infarction (DEDICATION) trial","volume":"118","author":"Kelbaek","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2014.04.022_bib21","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.jacc.2007.04.029","article-title":"Two-year clinical follow-up after sirolimus-eluting versus bare-metal stent implantation assisted by systematic glycoprotein IIb\/IIIa Inhibitor Infusion in patients with myocardial infarction: results from the STRATEGY study","volume":"50","author":"Valgimigli","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2014.04.022_bib22","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1056\/NEJMoa0810116","article-title":"Paclitaxel-eluting stents versus bare-metal stents in acute myocardial infarction","volume":"360","author":"Stone","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2014.04.022_bib23","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1161\/CIRCULATIONAHA.106.685313","article-title":"Clinical end points in coronary stent trials: a case for standardized definitions","volume":"115","author":"Cutlip","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2014.04.022_bib24","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1093\/eurheartj\/ehr479","article-title":"Lower risk of stent thrombosis and restenosis with unrestricted use of 'new-generation' drug-eluting stents: a report from the nationwide Swedish Coronary Angiography and Angioplasty Registry (SCAAR)","volume":"33","author":"Sarno","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2014.04.022_bib25","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1016\/j.jacc.2009.08.009","article-title":"The 5-year clinical outcomes after a randomized comparison of sirolimus-eluting versus bare-metal stent implantation in patients with ST-segment elevation myocardial infarction","volume":"54","author":"Tebaldi","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2014.04.022_bib26","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1056\/NEJMoa062006","article-title":"Sirolimus-eluting versus uncoated stents in acute myocardial infarction","volume":"355","author":"Spaulding","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2014.04.022_bib27","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.jcin.2009.03.012","article-title":"The PASEO (PaclitAxel or Sirolimus-Eluting Stent Versus Bare Metal Stent in Primary Angioplasty) Randomized Trial","volume":"2","author":"Di Lorenzo","year":"2009","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2014.04.022_bib28","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jcin.2010.11.003","volume":"4","author":"Vink","year":"2011","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2014.04.022_bib29","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1161\/CIRCINTERVENTIONS.108.787762","article-title":"Primary percutaneous coronary intervention for acute myocardial infarction: long-term outcome after bare metal and drug-eluting stent implantation","volume":"1","author":"Kukreja","year":"2008","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2014.04.022_bib30","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1001\/archinternmed.2012.758","article-title":"Drug-eluting vs bare-metal stents in primary angioplasty: a pooled patient-level meta-analysis of randomized trials","volume":"172","author":"De Luca","year":"2012","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jacc.2014.04.022_bib31","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1093\/eurheartj\/ehs215","article-title":"ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation","volume":"33","author":"Steg","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2014.04.022_bib32","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1093\/eurheartj\/ehs036","article-title":"Comparison of drug-eluting stents with bare metal stents in patients with ST-segment elevation myocardial infarction","volume":"33","author":"Kalesan","year":"2012","journal-title":"Eur Heart J"},{"issue":"Suppl","key":"10.1016\/j.jacc.2014.04.022_bib33","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.jacc.2010.06.007","article-title":"Coronary stents: current status","volume":"56","author":"Garg","year":"2010","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2014.04.022_bib34","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1097\/00019501-200409000-00003","article-title":"Drug-eluting stents: caution and concerns for long-term outcome","volume":"15","author":"Virmani","year":"2004","journal-title":"Coron Art Dis"},{"key":"10.1016\/j.jacc.2014.04.022_bib35","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1161\/ATVBAHA.107.144220","article-title":"Vascular responses to drug eluting stents: importance of delayed healing","volume":"27","author":"Finn","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jacc.2014.04.022_bib36","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.jacc.2010.05.066","article-title":"Coronary responses and differential mechanisms of late stent thrombosis attributed to first-generation sirolimus- and paclitaxel-eluting stents","volume":"57","author":"Nakazawa","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2014.04.022_bib37","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1016\/j.jacc.2011.01.011","article-title":"The pathology of neoatherosclerosis in human coronary implants bare-metal and drug-eluting stents","volume":"57","author":"Nakazawa","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2014.04.022_bib38","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1161\/CIRCINTERVENTIONS.113.000415","article-title":"Outcomes with various drug-eluting or bare metal stents in patients with ST-segment-elevation myocardial infarction: a mixed treatment comparison analysis of trial level data from 34 068 patient-years of follow-up from randomized trials","volume":"6","author":"Bangalore","year":"2013","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2014.04.022_bib39","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1161\/01.CIR.85.3.916","article-title":"Intracoronary stenting for acute and threatened closure complicating percutaneous transluminal coronary angioplasty","volume":"85","author":"Roubin","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2014.04.022_bib40","doi-asserted-by":"crossref","first-page":"2716","DOI":"10.1161\/01.CIR.90.6.2716","article-title":"Four-year experience with Palmaz-Schatz stenting in coronary angioplasty complicated by dissection with threatened or present vessel closure","volume":"90","author":"Schomig","year":"1994","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2014.04.022_bib41","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1161\/CIRCULATIONAHA.106.666826","article-title":"Are drug-eluting stents associated with a higher rate of late thrombosis than bare metal stents? Late stent thrombosis: a nuisance in both bare metal and drug-eluting stents","volume":"115","author":"Serruys","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2014.04.022_bib42","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1001\/jama.293.17.2126","article-title":"Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents","volume":"293","author":"Iakovou","year":"2005","journal-title":"JAMA"}],"updated-by":[{"DOI":"10.1016\/j.jacc.2014.07.009","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2014,8,19]],"date-time":"2014-08-19T00:00:00Z","timestamp":1408406400000}}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109714023304?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109714023304?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T19:28:22Z","timestamp":1538422102000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109714023304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S0735109714023304"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2014.04.022","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.jacc.2014.07.009","asserted-by":"object"}]},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stent Thrombosis in New-Generation Drug-Eluting Stents in Patients With STEMI Undergoing Primary PCI","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2014.04.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}