{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:39:46Z","timestamp":1790419186924,"version":"4.1.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"16","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,8,25]],"date-time":"2015-08-25T00:00:00Z","timestamp":1440460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.jacc.2015.07.075","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T00:46:05Z","timestamp":1444697165000},"page":"1747-1761","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":304,"title":["Risk Assessment and Comparative Effectiveness of Left Ventricular Assist\u00a0Device and Medical Management in\u00a0Ambulatory Heart Failure Patients"],"prefix":"10.1016","volume":"66","author":[{"given":"Jerry D.","family":"Estep","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randall C.","family":"Starling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas A.","family":"Horstmanshof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmelo A.","family":"Milano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig H.","family":"Selzman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keyur B.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Loebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nader","family":"Moazami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James W.","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josef","family":"Stehlik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vigneshwar","family":"Kasirajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald C.","family":"Haas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John B.","family":"O'Connell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Boyle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Farrar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph G.","family":"Rogers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2015.07.075_bib1","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1056\/NEJMoa012175","article-title":"Long-term use of a left ventricular assist device for end-stage heart failure","volume":"345","author":"Rose","year":"2001","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2015.07.075_bib2","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1056\/NEJMoa067758","article-title":"Use of a continuous-flow device in patients awaiting heart transplantation","volume":"357","author":"Miller","year":"2007","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2015.07.075_bib3","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1056\/NEJMoa0909938","article-title":"Advanced heart failure treated with continuous-flow left ventricular assist device","volume":"361","author":"Slaughter","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2015.07.075_bib4","doi-asserted-by":"crossref","first-page":"e147","DOI":"10.1016\/j.jacc.2013.05.019","article-title":"2013 ACCF\/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"62","author":"Yancy","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.07.075_bib5","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.healun.2014.04.010","article-title":"Sixth INTERMACS annual report: a 10,000-patient database","volume":"33","author":"Kirklin","year":"2014","journal-title":"J\u00a0Heart Lung Transplant"},{"key":"10.1016\/j.jacc.2015.07.075_bib6","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.healun.2010.10.016","article-title":"Clinical outcomes for continuous-flow left ventricular assist device patients stratified by pre-operative INTERMACS classification","volume":"30","author":"Boyle","year":"2011","journal-title":"J\u00a0Heart Lung Transplant"},{"key":"10.1016\/j.jacc.2015.07.075_bib7","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1016\/j.jacc.2014.01.053","article-title":"Results of the destination therapy post-Food and Drug Administration approval study with a continuous flow left ventricular assist device: a prospective study using the INTERMACS registry (Interagency Registry for Mechanically Assisted Circulatory Support)","volume":"63","author":"Jorde","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.07.075_bib8","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.healun.2013.10.017","article-title":"Overall quality of life improves to similar levels\u00a0after mechanical circulatory support regardless of severity of heart failure before implantation","volume":"33","author":"Grady","year":"2014","journal-title":"J\u00a0Heart Lung Transplant"},{"key":"10.1016\/j.jacc.2015.07.075_bib9","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.ahj.2014.11.004","article-title":"Risk assessment and comparative effectiveness of left ventricular assist device and medical management in ambulatory heart failure patients: design and rationale of the ROADMAP clinical trial","volume":"169","author":"Rogers","year":"2015","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacc.2015.07.075_bib10","doi-asserted-by":"crossref","first-page":"337","DOI":"10.3109\/07853890109002087","article-title":"EQ-5D: a measure of health status from the EuroQol Group","volume":"33","author":"Rabin","year":"2001","journal-title":"Ann Med"},{"key":"10.1016\/j.jacc.2015.07.075_bib11","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9: validity of a brief depression severity measure","volume":"16","author":"Kroenke","year":"2001","journal-title":"J\u00a0Gen Intern Med"},{"key":"10.1016\/j.jacc.2015.07.075_bib12","doi-asserted-by":"crossref","first-page":"3191","DOI":"10.1161\/CIRCULATIONAHA.111.058412","article-title":"Use of an intrapericardial, continuous-flow, centrifugal pump in patients awaiting heart transplantation","volume":"125","author":"Aaronson","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2015.07.075_bib13","doi-asserted-by":"crossref","unstructured":"Stewart GC, Teuteberg JJ, Kittleson M, et\u00a0al. INTERMACS Profiling Identifies Risk of Death or VAD among Medically-Managed Advanced Heart Failure Patients. Paper presented at: ISHLT 33rd Annual Meeting & Scientific Sessions; April 24-27, 2013; Montreal, Quebec, Canada.","DOI":"10.1016\/j.healun.2013.01.296"},{"key":"10.1016\/j.jacc.2015.07.075_bib14","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/S0022-5223(99)70052-8","article-title":"Impact of the maze procedure on the stroke rate in patients with atrial fibrillation","volume":"118","author":"Cox","year":"1999","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jacc.2015.07.075_bib15","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1212\/WNL.54.2.288","article-title":"Stroke in patients with heart failure and reduced left ventricular ejection fraction","volume":"54","author":"Pullicino","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.jacc.2015.07.075_bib16","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1161\/CIRCHEARTFAILURE.111.963991","article-title":"Outcomes in advanced heart failure patients with left ventricular assist devices for destination therapy","volume":"5","author":"Park","year":"2012","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jacc.2015.07.075_bib17","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1056\/NEJMoa1313385","article-title":"Unexpected abrupt increase in left ventricular assist device thrombosis","volume":"370","author":"Starling","year":"2014","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2015.07.075_bib18","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.healun.2013.11.001","article-title":"Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) analysis of pump\u00a0thrombosis in the HeartMate II left ventricular assist device","volume":"33","author":"Kirklin","year":"2014","journal-title":"J\u00a0Heart Lung Transplant"},{"key":"10.1016\/j.jacc.2015.07.075_bib19","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/j.healun.2014.11.021","article-title":"Reduction in driveline infection rates: results from the HeartMate II Multicenter Driveline Silicone Skin Interface (SSI) Registry","volume":"34","author":"Dean","year":"2015","journal-title":"J\u00a0Heart Lung Transplant"},{"key":"10.1016\/j.jacc.2015.07.075_bib20","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1161\/CIRCULATIONAHA.106.629261","article-title":"Effects of cardiac resynchronization therapy with or without a defibrillator on survival and hospitalizations in patients with New York Heart Association class IV heart failure","volume":"115","author":"Lindenfeld","year":"2007","journal-title":"Circulation"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109715048779?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109715048779?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T00:32:44Z","timestamp":1653265964000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109715048779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":20,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["S0735109715048779"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2015.07.075","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk Assessment and Comparative Effectiveness of Left Ventricular Assist\u00a0Device and Medical Management in\u00a0Ambulatory Heart Failure Patients","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2015.07.075","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2015 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}