{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T08:45:29Z","timestamp":1793090729542,"version":"4.5.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T00:00:00Z","timestamp":1490918400000},"content-version":"vor","delay-in-days":395,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.jacc.2015.12.054","type":"journal-article","created":{"date-parts":[[2016,3,7]],"date-time":"2016-03-07T19:16:44Z","timestamp":1457378204000},"page":"1129-1140","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":170,"title":["Initial Experience With Commercial Transcatheter Mitral Valve Repair in\u00a0the\u00a0United States"],"prefix":"10.1016","volume":"67","author":[{"given":"Paul","family":"Sorajja","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Mack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreekanth","family":"Vemulapalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"David R.","family":"Holmes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Stebbins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saibal","family":"Kar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. Scott","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinod","family":"Thourani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"McCarthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir","family":"Kapadia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Grayburn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wesley A.","family":"Pedersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gorav","family":"Ailawadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2015.12.054_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM199907013410101","article-title":"Prevalence and clinical outcome of mitral-valve prolapse","volume":"341","author":"Freed","year":"1999","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2015.12.054_bib2","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1161\/01.CIR.90.2.830","article-title":"Echocardiographic prediction of survival after surgical correction of organic mitral regurgitation","volume":"90","author":"Enriquez-Sarano","year":"1994","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2015.12.054_bib3","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1056\/NEJM199611073351902","article-title":"Clinical outcome of mitral regurgitation due to flail leaflet","volume":"335","author":"Ling","year":"1996","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2015.12.054_bib4","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1161\/01.CIR.99.3.400","article-title":"Impact of preoperative symptoms on survival after surgical correction of organic mitral regurgitation: rationale for optimizing surgical indications","volume":"99","author":"Tribouilly","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2015.12.054_bib5","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.jcmg.2007.12.005","article-title":"Outcomes in mitral regurgitation due to flail leaflets: a multicenter European study","volume":"1","author":"Grigioni","year":"2008","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jacc.2015.12.054_bib6","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1056\/NEJMoa041451","article-title":"Quantitative determinants of the outcome of asymptomatic mitral regurgitation","volume":"352","author":"Enriquez-Sarano","year":"2005","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2015.12.054_bib7","doi-asserted-by":"crossref","first-page":"e57","DOI":"10.1016\/j.jacc.2014.02.536","article-title":"2014 AHA\/ACC guideline for the management of patients with valvular heart disease. A report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines","volume":"63","author":"Nishimura","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib8","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1093\/eurheartj\/ehm001","article-title":"What are the characteristics of patients with severe, symptomatic mitral regurgitation who are denied surgery?","volume":"28","author":"Mirabel","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2015.12.054_bib9","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jacc.2013.08.723","article-title":"Prevalence and outcomes of unoperated patients with severe symptomatic mitral regurgitation and heart failure: comprehensive analysis to determine the potential role of MitraClip for this unmet need","volume":"63","author":"Goel","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib10","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.jacc.2013.10.021","article-title":"Improved functional status and quality of life in prohibitive surgical risk patients with degenerative mitral regurgitation after transcatheter mitral valve repair","volume":"64","author":"Lim","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib11","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1056\/NEJMoa1009355","article-title":"Percutaneous repair or surgery for mitral regurgitation","volume":"364","author":"Feldman","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2015.12.054_bib12","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jacc.2013.04.030","article-title":"4-Year results of a randomized controlled trial of percutaneous repair versus surgery for mitral regurgitation","volume":"62","author":"Mauri","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib13","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1016\/j.jacc.2005.07.065","article-title":"Percutaneous mitral valve repair using the edge-to-edge technique. Six-month results of the EVEREST phase I clinical trial","volume":"46","author":"Feldman","year":"2005","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib14","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.jacc.2013.03.060","article-title":"The STS-ACC Transcatheter Valve Therapy National Registry: a new partnership and infrastructure for the introduction and surveillance of medical devices and therapies","volume":"62","author":"Carroll","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib15","unstructured":"American College of Cardiology, Society of Thoracic Surgeons. ACC\/STS TVT Registry: home. Available at: https:\/\/www.ncdr.com\/TVT\/Home\/Default.aspx. Accessed February 6,\u00a02015."},{"key":"10.1016\/j.jacc.2015.12.054_bib16","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1001\/jama.2013.282043","article-title":"Outcomes following transcatheter aortic valve replacement in the United States","volume":"310","author":"Mack","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2015.12.054_bib17","unstructured":"American College of Cardiology, Society of Thoracic Surgeons. ACC\/STS TVT Registry: data collection. Available at: https:\/\/www.ncdr.com\/webncdr\/tvt\/home\/data-collection. Accessed February 6,\u00a02015."},{"key":"10.1016\/j.jacc.2015.12.054_bib18","unstructured":"Society of Thoracic Surgeons. Online STS adult cardiac surgery risk calculator. Available at: http:\/\/riskcalc.sts.org\/STSWebRiskCalc273. Accessed February 6,\u00a02015."},{"key":"10.1016\/j.jacc.2015.12.054_bib19","unstructured":"American College of Cardiology, Society of Thoracic Surgeons. ACC\/STS TVT Registry: participant directory. Available at: https:\/\/www.ncdr.com\/WebNCDR\/tvt\/home\/participantdirectory. Accessed February 6,\u00a02015."},{"key":"10.1016\/j.jacc.2015.12.054_bib20","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.jacc.2010.12.005","article-title":"Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium","volume":"57","author":"Leon","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib21","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/j.jacc.2012.09.001","article-title":"Updated standardized endpoint definition for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document","volume":"60","author":"Kappetein","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib22","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.jacc.2014.06.1166","article-title":"Percutaneous mitral valve edge-to-edge repair. In-hospital results and 1-year follow-up of 628 patients of the 2011\u20132012 pilot European Sentinel Registry","volume":"64","author":"Nickenig","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib23","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.jacc.2013.12.062","article-title":"Percutaneous mitral valve repair for mitral regurgitation in high-risk patients: results of the EVEREST II study","volume":"64","author":"Glower","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib24","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1016\/j.jacc.2013.02.094","article-title":"Percutaneous mitral valve interventions in the real world. Early and 1-year results from the ACCESS-EU, a prospective, multicenter, nonrandomized post-approval study of the MitraClip therapy in Europe","volume":"62","author":"Maisano","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib25","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/j.1540-8183.2011.00688.x","article-title":"In-hospital outcome of patients with severe mitral valve regurgitation classified as inoperable and treated with the MitraClip device","volume":"25","author":"Divchev","year":"2012","journal-title":"J\u00a0Interv Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib26","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1016\/j.amjcard.2013.01.300","article-title":"One- and twelve-month safety and efficacy outcomes of patients undergoing edge-to-edge percutaneous mitral valve repair (from the GRASP Registry)","volume":"111","author":"Grasso","year":"2013","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2015.12.054_bib27","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.acvd.2013.03.059","article-title":"Initial French experience of percutaneous mitral valve repair with the MitraClip: a multicenter national registry","volume":"106","author":"Armoiry","year":"2013","journal-title":"Arch Cardiovasc Dis"},{"key":"10.1016\/j.jacc.2015.12.054_bib28","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1093\/eurjhf\/hft046","article-title":"One year clinical efficacy and reverse cardiac remodeling in patients with severe mitral regurgitation and reduce ejection fraction after MitraClip implantation","volume":"15","author":"Pleger","year":"2013","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.jacc.2015.12.054_bib29","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1093\/eurheartj\/ehq050","article-title":"Acute outcomes of MitraClip therapy for mitral regurgitation in high-surgical-risk patients: emphasis on adverse valve morphology and severe left ventricular dysfunction","volume":"31","author":"Franzen","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2015.12.054_bib30","doi-asserted-by":"crossref","first-page":"84","DOI":"10.4244\/EIJV9I1A13","article-title":"Acute outcomes after MitraClip therapy in highly aged patients: results from the German Transcatheter Mitral Valve Interventions (TRAMI) Registry","volume":"9","author":"Schillinger","year":"2013","journal-title":"Eurointervention"},{"key":"10.1016\/j.jacc.2015.12.054_bib31","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1093\/ejcts\/ezs294","article-title":"MitraClip therapy and surgical mitral repair in patients with moderate to severe left ventricular failure causing functional mitral regurgitation: a single-centre experience","volume":"42","author":"Taramasso","year":"2012","journal-title":"Eur J CT Surg"},{"key":"10.1016\/j.jacc.2015.12.054_bib32","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.jcin.2014.01.171","article-title":"Survival of transcatheter mitral valve repair compared with surgical and conservative treatment in high-surgical-risk patients","volume":"7","author":"Swaans","year":"2014","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2015.12.054_bib33","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1136\/heartjnl-2012-303105","article-title":"Predictors for efficacy of percutaneous mitral valve repair using the MitraClip system: the results of the MitraSwiss registry","volume":"99","author":"Surder","year":"2013","journal-title":"Heart"},{"key":"10.1016\/j.jacc.2015.12.054_bib34","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1161\/CIRCULATIONAHA.112.001402","article-title":"Learning minimally invasive mitral valve surgery: a cumulative sum sequential probability analysis of 3,895 operations from a single high-volume center","volume":"128","author":"Holzhey","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2015.12.054_bib35","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1002\/ccd.22961","article-title":"Transcatheter aortic valve implantation: lessons from the learning curve of the first 270 high-risk patients","volume":"78","author":"Gurvitch","year":"2011","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2015.12.054_bib36","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.jcin.2014.01.159","article-title":"The learning curve in percutaneous repair of paravalvular prosthetic regurgitation: an analysis of 200 cases","volume":"7","author":"Sorajja","year":"2014","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2015.12.054_bib37","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1093\/ehjci\/jeu114","article-title":"Association of tricuspid regurgitation with clinical and echocardiographic outcomes after percutaneous mitral valve repair with the MitraClip System: 30-day and 12-month follow-up from the GRASP Registry","volume":"15","author":"Ohno","year":"2014","journal-title":"Eur Heart J Cardiovasc Imaging"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109716002308?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109716002308?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,2]],"date-time":"2022-07-02T06:43:28Z","timestamp":1656744208000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109716002308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":37,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["S0735109716002308"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2015.12.054","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Initial Experience With Commercial Transcatheter Mitral Valve Repair in\u00a0the\u00a0United States","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2015.12.054","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}