{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:08:39Z","timestamp":1791410919045,"version":"4.3.3"},"reference-count":36,"publisher":"Elsevier BV","issue":"25","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,12,27]],"date-time":"2017-12-27T00:00:00Z","timestamp":1514332800000},"content-version":"vor","delay-in-days":391,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.jacc.2016.10.041","type":"journal-article","created":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T14:16:10Z","timestamp":1482156970000},"page":"2733-2744","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":217,"title":["Sex-Based Differences in Outcomes With Transcatheter Aortic Valve Therapy"],"prefix":"10.1016","volume":"68","author":[{"given":"Jaya","family":"Chandrasekhar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Dangas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreekanth","family":"Vemulapalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Suchindran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit N.","family":"Vora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usman","family":"Baber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana","family":"Mehran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2016.10.041_bib1","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1001\/jama.2015.1474","article-title":"Clinical outcomes at 1 year following transcatheter aortic valve replacement","volume":"313","author":"Holmes","year":"2015","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2016.10.041_bib2","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.1056\/NEJMoa1500893","article-title":"Effect of availability of transcatheter aortic-valve replacement on clinical practice","volume":"373","author":"Reinohl","year":"2015","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2016.10.041_bib3","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1001\/jama.2013.282043","article-title":"Outcomes following transcatheter aortic valve replacement in the United States","volume":"310","author":"Mack","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2016.10.041_bib4","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jacc.2015.05.024","article-title":"Revisiting sex equality with transcatheter aortic valve replacement outcomes: a collaborative, patient-level meta-analysis of 11,310 patients","volume":"66","author":"O'Connor","year":"2015","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2016.10.041_bib5","doi-asserted-by":"crossref","first-page":"377","DOI":"10.7326\/M15-0121","article-title":"Sex-specific differences at presentation and outcomes among patients undergoing transcatheter aortic valve replacement: a cohort study","volume":"164","author":"Kodali","year":"2016","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jacc.2016.10.041_bib6","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1016\/j.jacc.2014.08.052","article-title":"Incidence, predictors, and prognostic impact of late bleeding complications after transcatheter aortic valve replacement","volume":"64","author":"Genereux","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2016.10.041_bib7","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.jacc.2012.07.003","article-title":"Vascular complications after transcatheter aortic valve replacement: insights from the PARTNER (Placement of AoRTic TraNscathetER Valve) trial","volume":"60","author":"Genereux","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2016.10.041_bib8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S1010-7940(02)00208-7","article-title":"Validation of European System for Cardiac Operative Risk Evaluation (EuroSCORE) in North American cardiac surgery","volume":"22","author":"Nashef","year":"2002","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jacc.2016.10.041_bib9","unstructured":"STS. Online STS Adult Cardiac Risk Surgery Calculator. Available at: http:\/\/riskcalc.sts.org\/stswebriskcalc. Accessed April 1, 2016."},{"key":"10.1016\/j.jacc.2016.10.041_bib10","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1510\/icvts.2006.138313","article-title":"The performance of the EuroSCORE and the Society of Thoracic Surgeons mortality risk score: the gender factor","volume":"6","author":"Ad","year":"2007","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"10.1016\/j.jacc.2016.10.041_bib11","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.jacc.2011.10.877","article-title":"Sex-related differences in clinical presentation and outcome of transcatheter aortic valve implantation for severe aortic stenosis","volume":"59","author":"Hayashida","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2016.10.041_bib12","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.jacc.2012.05.009","article-title":"Sex differences in mortality after transcatheter aortic valve replacement for severe aortic stenosis","volume":"60","author":"Humphries","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2016.10.041_bib13","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.jtcvs.2012.09.002","article-title":"Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document","volume":"145","author":"Kappetein","year":"2013","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jacc.2016.10.041_bib14","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","article-title":"A\u00a0proportional hazards model for the subdistribution of a competing risk","volume":"94","author":"Fine","year":"1999","journal-title":"J\u00a0Am Stat Assoc"},{"key":"10.1016\/j.jacc.2016.10.041_bib15","first-page":"46","article-title":"Development and validation of a risk prediction model for in-hospital mortality after transcatheter aortic valve replacement","volume":"1","author":"Edwards","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2016.10.041_bib16","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1016\/j.jacc.2014.01.036","article-title":"Sex-related differences in outcomes after transcatheter or surgical aortic valve replacement in patients with severe aortic stenosis: insights from the PARTNER Trial (Placement of Aortic Transcatheter Valve)","volume":"63","author":"Williams","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2016.10.041_bib17","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.amjcard.2013.03.024","article-title":"Predictors of one-year mortality after transcatheter aortic valve implantation for severe symptomatic aortic stenosis","volume":"112","author":"Zahn","year":"2013","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2016.10.041_bib18","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/j.jcin.2012.06.011","article-title":"The impact of frailty status on survival after transcatheter aortic valve replacement in older adults with severe aortic stenosis: a single-center experience","volume":"5","author":"Green","year":"2012","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2016.10.041_bib19","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.jcin.2012.07.002","article-title":"Working toward a frailty index in transcatheter aortic valve replacement: a major move away from the \u201ceyeball test.\u201d","volume":"5","author":"Rodes-Cabau","year":"2012","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2016.10.041_bib20","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1002\/ccd.25991","article-title":"Poor mobility predicts adverse outcome better than other frailty indices in patients undergoing transcatheter aortic valve implantation","volume":"86","author":"Cockburn","year":"2015","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2016.10.041_bib21","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1002\/ccd.26328","article-title":"Poor mobility independently predicts mortality in TAVI: are we closer to a universal definition for frailty?","volume":"86","author":"Chandrasekhar","year":"2015","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2016.10.041_bib22","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMoa1514616","article-title":"Transcatheter or surgical aortic-valve replacement in intermediate-risk patients","volume":"374","author":"Leon","year":"2016","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2016.10.041_bib23","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1056\/NEJMoa1103510","article-title":"Transcatheter versus surgical aortic-valve replacement in high-risk patients","volume":"364","author":"Smith","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2016.10.041_bib24","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1016\/j.cjca.2015.04.023","article-title":"Transfemoral vs non-transfemoral access for transcatheter aortic valve implantation: a systematic review and meta-analysis","volume":"31","author":"Chandrasekhar","year":"2015","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.jacc.2016.10.041_bib25","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.jcin.2012.03.009","article-title":"Access for transcatheter aortic valve replacement: which is the preferred route?","volume":"5","author":"Mack","year":"2012","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2016.10.041_bib26","doi-asserted-by":"crossref","first-page":"2810","DOI":"10.1001\/jama.283.21.2810","article-title":"Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease","volume":"283","author":"Iribarren","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2016.10.041_bib27","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0009-9260(84)80228-7","article-title":"Age-related changes in the abdominal aorta shown by computed tomography","volume":"35","author":"Dixon","year":"1984","journal-title":"Clin Radiol"},{"key":"10.1016\/j.jacc.2016.10.041_bib28","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.jcin.2012.09.007","article-title":"Aortic root dimensions among patients with severe aortic stenosis undergoing transcatheter aortic valve\u00a0replacement","volume":"6","author":"Buellesfeld","year":"2013","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2016.10.041_bib29","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.jcin.2011.03.019","article-title":"Transfemoral aortic valve implantation new criteria to predict vascular complications","volume":"4","author":"Hayashida","year":"2011","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2016.10.041_bib30","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1016\/j.jacc.2015.10.021","article-title":"Annual outcomes with transcatheter valve therapy: from the STS\/ACC TVT Registry","volume":"66","author":"Holmes","year":"2015","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2016.10.041_bib31","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1161\/CIRCULATIONAHA.109.929893","article-title":"Comparison between transcatheter and surgical prosthetic valve implantation in patients with severe aortic stenosis and reduced left ventricular ejection fraction","volume":"122","author":"Clavel","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2016.10.041_bib32","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.1161\/CIRCULATIONAHA.109.927764","article-title":"Regression of myocardial hypertrophy after aortic valve replacement: faster in women?","volume":"122 Suppl 11","author":"Petrov","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2016.10.041_bib33","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.jcin.2014.02.011","article-title":"Early regression of severe left ventricular hypertrophy after transcatheter aortic valve replacement is associated with decreased hospitalizations","volume":"7","author":"Lindman","year":"2014","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2016.10.041_bib34","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jcct.2015.12.004","article-title":"3D printing based on cardiac CT assists anatomic visualization prior to transcatheter aortic valve replacement","volume":"10","author":"Ripley","year":"2016","journal-title":"J\u00a0Cardiovasc Comput Tomogr"},{"key":"10.1016\/j.jacc.2016.10.041_bib35","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/nrcardio.2016.42","article-title":"Big data analytics to improve cardiovascular care: promise and challenges","volume":"13","author":"Rumsfeld","year":"2016","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jacc.2016.10.041_bib36","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1161\/CIRCULATIONAHA.115.018610","article-title":"Study of cardiovascular health outcomes in the era of claims data: the Cardiovascular Health Study","volume":"133","author":"Psaty","year":"2016","journal-title":"Circulation"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109716368450?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109716368450?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T15:52:16Z","timestamp":1536162736000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109716368450"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":36,"journal-issue":{"issue":"25","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S0735109716368450"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2016.10.041","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sex-Based Differences in Outcomes With Transcatheter Aortic Valve Therapy","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2016.10.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}