{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:37:27Z","timestamp":1792640247097,"version":"4.5.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,12,7]],"date-time":"2017-12-07T00:00:00Z","timestamp":1512604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.jacc.2017.11.053","type":"journal-article","created":{"date-parts":[[2018,1,29]],"date-time":"2018-01-29T14:16:57Z","timestamp":1517235417000},"page":"513-523","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":151,"title":["18F\u2013Sodium Fluoride Uptake in Abdominal\u00a0Aortic Aneurysms"],"prefix":"10.1016","volume":"71","author":[{"given":"Rachael O.","family":"Forsythe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc R.","family":"Dweck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia M.B.","family":"McBride","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex T.","family":"Vesey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott I.","family":"Semple","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anoop S.V.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip D.","family":"Adamson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Wallace","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakub","family":"Kaczynski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyang","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin J.R.","family":"van Beek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calum D.","family":"Gray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Fletcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Lucatelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksander","family":"Marin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Burns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Tambyraja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roderick T.A.","family":"Chalmers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme","family":"Weir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Mitchard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Tavares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer M.J.","family":"Robson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E.","family":"Newby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2017.11.053_bib1","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1002\/bjs.9838","article-title":"Age-specific incidence, risk factors and outcome of acute abdominal aortic aneurysms in a defined population","volume":"102","author":"Howard","year":"2015","journal-title":"Br J Surg"},{"key":"10.1016\/j.jacc.2017.11.053_bib2","unstructured":"Office for National Statistics. Leading causes of death 2013. Available at: http:\/\/visual.ons.gov.uk\/wp-content\/uploads\/2015\/02\/Leading-Causes-of-Deaths-20131.csv. Accessed February 16,\u00a02017."},{"key":"10.1016\/j.jacc.2017.11.053_bib3","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1161\/01.CIR.0000133279.07468.9F","article-title":"Abdominal aortic aneurysm expansion: risk factors and time intervals for surveillance","volume":"110","author":"Brady","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2017.11.053_bib4","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1001\/jama.2013.950","article-title":"Surveillance intervals for small abdominal aortic aneurysms: a meta-analysis","volume":"309","author":"Bown","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2017.11.053_bib5","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.jamcollsurg.2004.07.031","article-title":"Discontinuous, staccato growth of abdominal aortic aneurysms","volume":"199","author":"Kurvers","year":"2004","journal-title":"J\u00a0Am Coll Surg"},{"key":"10.1016\/j.jacc.2017.11.053_bib6","first-page":"161","article-title":"Autopsy study of unoperated abdominal aortic-aneurysms\u2014case for early resection","volume":"56","author":"Darling","year":"1977","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2017.11.053_bib7","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1136\/heartjnl-2015-308779","article-title":"Monitoring the biological activity of abdominal aortic aneurysms: beyond ultrasound","volume":"102","author":"Forsythe","year":"2016","journal-title":"Heart"},{"key":"10.1016\/j.jacc.2017.11.053_bib8","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1155\/2009\/352319","article-title":"A\u00a0systematic review of studies examining inflammation associated cytokines in human abdominal aortic aneurysm samples","volume":"26","author":"Golledge","year":"2009","journal-title":"Dis Markers"},{"key":"10.1016\/j.jacc.2017.11.053_bib9","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/S1078-5884(96)80183-3","article-title":"Angiogenesis in abdominal aortic aneurysms","volume":"11","author":"Thompson","year":"1996","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jacc.2017.11.053_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/ncomms8495","article-title":"Identifying active vascular micro-calcification by 18F-sodium fluoride positron emission tomography","volume":"6","author":"Irkle","year":"2015","journal-title":"Nat Commun"},{"key":"10.1016\/j.jacc.2017.11.053_bib11","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.116.004976","article-title":"18F-fluoride and 18F-fluorodeoxyglucose positron emission tomography after transient ischemic attack or minor ischemic stroke. case-control study","volume":"10","author":"Vesey","year":"2017","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.jacc.2017.11.053_bib12","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/S0140-6736(13)61754-7","article-title":"18F-fluoride positron emission tomography for identification of ruptured and high-risk coronary atherosclerotic plaques: a prospective clinical trial","volume":"383","author":"Joshi","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2017.11.053_bib13","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2014-000190","article-title":"MRI using ultrasmall superparamagnetic particles of iron oxide in patients under surveillance for abdominal aortic aneurysms to predict rupture or surgical repair: MRI for abdominal aortic aneurysms to predict rupture or surgery\u2014the MA3RS study","volume":"2","author":"McBride","year":"2015","journal-title":"Open Heart"},{"key":"10.1016\/j.jacc.2017.11.053_bib14","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1067\/mva.2000.102131","article-title":"Ultrasonic measurement of abdominal aortic aneurysm wall compliance: a reproducibility study","volume":"31","author":"Wilson","year":"2000","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jacc.2017.11.053_bib15","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1583\/04-1239.1","article-title":"Heterogeneity of tensile strength and matrix metalloproteinase activity in the wall of abdominal aortic aneurysms","volume":"11","author":"Vallabhaneni","year":"2004","journal-title":"J\u00a0Endovasc Ther"},{"key":"10.1016\/j.jacc.2017.11.053_bib16","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.116.005131","article-title":"Optimization and reproducibility of aortic valve 18F-fluoride positron emission tomography in patients with aortic stenosis","volume":"9","author":"Pawade","year":"2016","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.jacc.2017.11.053_bib17","doi-asserted-by":"crossref","first-page":"503","DOI":"10.2967\/jnumed.115.154385","article-title":"PET assessment of vascular inflammation and atherosclerotic plaques: SUV or TBR?","volume":"56","author":"Chen","year":"2015","journal-title":"J\u00a0Nucl Med"},{"key":"10.1016\/j.jacc.2017.11.053_bib18","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1016\/S0140-6736(11)61383-4","article-title":"Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial","volume":"378","author":"Fayad","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2017.11.053_bib19","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.ahj.2011.05.006","article-title":"Rationale and design of dal-PLAQUE: a study assessing efficacy and safety of dalcetrapib on progression or regression of atherosclerosis using magnetic resonance imaging and 18F-fluorodeoxyglucose positron emission tomography\/computed tomography","volume":"162","author":"Fayad","year":"2011","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacc.2017.11.053_bib20","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.jacc.2013.04.066","article-title":"Intensification of statin therapy results in a rapid reduction in atherosclerotic inflammation: results of a multicenter fluorodeoxyglucose-positron emission tomography\/computed tomography feasibility study","volume":"62","author":"Tawakol","year":"2013","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2017.11.053_bib21","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.ejvs.2016.05.002","article-title":"Inflammation as a predictor of abdominal aortic aneurysm growth and rupture: a systematic review of imaging biomarkers","volume":"52","author":"Jalalzadeh","year":"2016","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jacc.2017.11.053_bib22","article-title":"Hybrid PET\/CT and PET\/MRI imaging of vulnerable coronary plaque and myocardial scar tissue in acute myocardial infarction","author":"Marchesseau","year":"2017","journal-title":"J\u00a0Nucl Cardiol"},{"key":"10.1016\/j.jacc.2017.11.053_bib23","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.2967\/jnumed.112.115873","article-title":"18F-FDG uptake assessed by PET\/CT in abdominal aortic aneurysms is associated with cellular and molecular alterations prefacing wall deterioration and rupture","volume":"54","author":"Courtois","year":"2013","journal-title":"J\u00a0Nucl Med"},{"key":"10.1016\/j.jacc.2017.11.053_bib24","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.jvs.2008.03.059","article-title":"Increased 18F-fluorodeoxyglucose uptake in abdominal aortic aneurysms in positron emission\/computed tomography is associated with inflammation, aortic wall instability, and acute symptoms","volume":"48","author":"Reeps","year":"2008","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jacc.2017.11.053_bib25","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1161\/CIRCIMAGING.112.000415","article-title":"Multifactorial relationship between 18F-fluoro-deoxy-glucose positron emission tomography signaling and biomechanical properties in unruptured aortic aneurysms","volume":"7","author":"Nchimi","year":"2014","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.jacc.2017.11.053_bib26","doi-asserted-by":"crossref","first-page":"2310","DOI":"10.1007\/s00259-014-2865-9","article-title":"18F-FDG PET-CT uptake is a feature of both normal diameter and aneurysmal aortic wall and is not related to aneurysm size","volume":"41","author":"Barwick","year":"2014","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.jacc.2017.11.053_bib27","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1007\/s00259-011-1799-8","article-title":"What is the relationship between 18F-FDG aortic aneurysm uptake on PET\/CT and future growth rate?","volume":"38","author":"Kotze","year":"2011","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.jacc.2017.11.053_bib28","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1161\/CIRCULATIONAHA.117.028433","article-title":"Aortic wall inflammation predicts abdominal aortic aneurysm expansion, rupture and need for surgical repair","volume":"136","year":"2017","journal-title":"Circulation"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109717417797?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109717417797?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:15:22Z","timestamp":1760015722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109717417797"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["S0735109717417797"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2017.11.053","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"18F\u2013Sodium Fluoride Uptake in Abdominal\u00a0Aortic Aneurysms","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2017.11.053","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}]}}