{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T08:07:00Z","timestamp":1767514020964,"version":"build-2065373602"},"reference-count":13,"publisher":"Elsevier BV","issue":"20","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,11,19]],"date-time":"2020-11-19T00:00:00Z","timestamp":1605744000000},"content-version":"vor","delay-in-days":384,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.jacc.2019.08.1059","type":"journal-article","created":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T15:54:55Z","timestamp":1573487695000},"page":"2493-2495","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Progression of Aortic Regurgitation"],"prefix":"10.1016","volume":"74","author":[{"given":"Jean-Louis","family":"Vanoverschelde","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Vancraeynest","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2019.08.1059_bib1","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1056\/NEJMe0807001","article-title":"Calcific aortic stenosis. Time to look more closely at the valve","volume":"359","author":"Otto","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2019.08.1059_bib2","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1056\/NEJM200008313430903","article-title":"Predictors of outcome in severe, asymptomatic aortic stenosis","volume":"343","author":"Rosenhek","year":"2000","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2019.08.1059_bib3","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1056\/NEJMoa041451","article-title":"Quantitative determinants of the outcome of asymptomatic mitral regurgitation","volume":"352","author":"Enriquez-Sarano","year":"2005","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2019.08.1059_bib4","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/S0735-1097(99)00313-7","article-title":"Progression of mitral regurgitation: a prospective Doppler echocardiographic study","volume":"34","author":"Enriquez-Sarano","year":"1999","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2019.08.1059_bib5","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1161\/CIRCULATIONAHA.117.033173","article-title":"Clinical outcome of degenerative mitral regurgitation. Critical importance of echocardiographic quantitative assessment in routine practice","volume":"138","author":"Antoine","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2019.08.1059_bib6","doi-asserted-by":"crossref","first-page":"2938","DOI":"10.1016\/j.jacc.2018.09.049","article-title":"Asymptomatic severe aortic stenosis with preserved ejection fraction. Early surgery versus conservative management","volume":"72","author":"Bohbot","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2019.08.1059_bib7","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1161\/01.CIR.98.18.1949","article-title":"Guidelines for the management of patients with valvular heart disease","volume":"98","author":"Bonow","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2019.08.1059_bib8","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1161\/01.CIR.99.14.1851","article-title":"Mortality and morbidity of aortic regurgitation in clinical practice. A long-term follow-up study","volume":"99","author":"Dujardin","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2019.08.1059_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jcmg.2007.10.008","article-title":"Quantitative echocardiographic determinants of clinical outcome in asymptomatic patients with aortic regurgitation: A prospective study","volume":"1","author":"Detaint","year":"2008","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jacc.2019.08.1059_bib10","doi-asserted-by":"crossref","first-page":"2480","DOI":"10.1016\/j.jacc.2019.08.1058","article-title":"Predictors of progression in patients with stage B aortic regurgitation","volume":"74","author":"Yang","year":"2019","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2019.08.1059_bib11","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0894-7317(98)70087-2","article-title":"Progressive enlargement of the regurgitant orifice in patients with aortic regurgitation","volume":"11","author":"Reimold","year":"1998","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.jacc.2019.08.1059_bib12","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1530\/ERP-17-0002","article-title":"Clinical events and echocardiographic lesion progression rate in subjects with mild of moderate aortic regurgitation","volume":"3","author":"Badiani","year":"2017","journal-title":"Echo Res Pract"},{"key":"10.1016\/j.jacc.2019.08.1059_bib13","doi-asserted-by":"crossref","first-page":"e292","DOI":"10.1161\/CIR.0000000000000241","article-title":"Eligibility and disqualification recommendations for competitive athletes with cardiovascular abnormalities: Task Force 5: valvular heart disease","volume":"132","author":"Bonow","year":"2015","journal-title":"Circulation"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109719377307?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109719377307?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:24:54Z","timestamp":1760016294000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109719377307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":13,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["S0735109719377307"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2019.08.1059","relation":{},"ISSN":["0735-1097"],"issn-type":[{"type":"print","value":"0735-1097"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Progression of Aortic Regurgitation","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2019.08.1059","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2019.08.1058","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}