{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T01:05:19Z","timestamp":1792890319790,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"20","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T00:00:00Z","timestamp":1637107200000},"content-version":"vor","delay-in-days":381,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100011949","name":"Abbott Vascular","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011949","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.jacc.2020.09.547","type":"journal-article","created":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T12:24:16Z","timestamp":1602764656000},"page":"2289-2301","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":226,"title":["Percutaneous Coronary Intervention for Vulnerable Coronary Atherosclerotic Plaque"],"prefix":"10.1016","volume":"76","author":[{"given":"Gregg W.","family":"Stone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiko","family":"Maehara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziad A.","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claes","family":"Held","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuaki","family":"Matsumura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Kj\u00f8ller-Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans Erik","family":"B\u00f8tker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Maeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Engstr\u00f8m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rune","family":"Wiseth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"Persson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thor","family":"Trovik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulf","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan K.","family":"James","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary S.","family":"Mintz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ovidiu","family":"Dressler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Crowley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ori","family":"Ben-Yehuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Erlinge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2020.09.547_bib1","doi-asserted-by":"crossref","first-page":"C13","DOI":"10.1016\/j.jacc.2005.10.065","article-title":"Pathology of the vulnerable plaque","volume":"47","author":"Virmani","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2020.09.547_bib2","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1161\/01.CIR.79.4.733","article-title":"Circadian variation and triggers of onset of acute cardiovascular disease","volume":"79","author":"Muller","year":"1989","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2020.09.547_bib3","doi-asserted-by":"crossref","first-page":"2997","DOI":"10.1093\/eurheartj\/ehaa227","article-title":"Vulnerable plaques and patients: state-of-the-art","volume":"41","author":"Tomaniak","year":"2020","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2020.09.547_bib4","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jacc.2009.02.068","article-title":"Computed tomographic angiography characteristics of atherosclerotic plaques subsequently resulting in acute coronary syndrome","volume":"54","author":"Motoyama","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2020.09.547_bib5","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1056\/NEJMoa1002358","article-title":"A\u00a0prospective natural-history study of coronary atherosclerosis [published correction appears in N Engl J Med 201124;365:2040]","volume":"364","author":"Stone","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2020.09.547_bib6","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.jcmg.2011.05.005","article-title":"Association between IVUS findings and adverse outcomes in patients with coronary artery disease: the VIVA (VH-IVUS in Vulnerable Atherosclerosis) Study","volume":"4","author":"Calvert","year":"2011","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jacc.2020.09.547_bib7","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1093\/eurheartj\/eht484","article-title":"In\u00a0vivo detection of high-risk coronary plaques by\u00a0radiofrequency intravascular ultrasound and\u00a0cardiovascular outcome: results of the ATHEROREMO-IVUS study","volume":"35","author":"Cheng","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2020.09.547_bib8","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1016\/S0140-6736(19)31794-5","article-title":"Identification of patients and plaques vulnerable to future coronary events with near-infrared spectroscopy intravascular ultrasound imaging: a prospective, cohort study [published correction appears in Lancet 2019;394:1618]","volume":"394","author":"Waksman","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2020.09.547_bib9","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/eurheartj\/ehz520","article-title":"Relationship between coronary plaque morphology of the left anterior descending artery and 12\u00a0months clinical outcome: the CLIMA study [published correction appears in Eur Heart J 2020;41:393]","volume":"41","author":"Prati","year":"2020","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2020.09.547_bib10","first-page":"1","article-title":"Vulnerable plaque: definition, diagnosis, and treatment","volume":"28","author":"Moreno","year":"2010","journal-title":"Cardiol Clin"},{"key":"10.1016\/j.jacc.2020.09.547_bib11","doi-asserted-by":"crossref","first-page":"746","DOI":"10.4244\/EIJY14M10_06","article-title":"Bioresorbable vascular scaffold treatment induces the formation of neointimal cap that seals the underlying plaque without compromising the luminal dimensions: a concept based on serial optical coherence tomography data","volume":"11","author":"Bourantas","year":"2015","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jacc.2020.09.547_bib12","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.ahj.2013.02.015","article-title":"Early detection and invasive passivation of future culprit lesions: a future potential or an unrealistic pursuit of chimeras?","volume":"165","author":"Bourantas","year":"2013","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacc.2020.09.547_bib13","first-page":"1271","article-title":"Head-to-head comparison of the neointimal response between metallic and bioresorbable everolimus-eluting scaffolds using optical coherence tomography","volume":"4","author":"Gomez-Lara","year":"2011","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jacc.2020.09.547_bib14","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.jcin.2013.05.034","article-title":"Effect of the endothelial shear stress patterns on neointimal proliferation following drug-eluting bioresorbable vascular scaffold implantation: an optical coherence tomography study","volume":"7","author":"Bourantas","year":"2014","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2020.09.547_bib15","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.119.008768","article-title":"Nonculprit lesion plaque morphology in patients with ST-segment-elevation myocardial infarction: results from the COMPLETE Trial optical coherence tomography substudys","volume":"13","author":"Pinilla-Echeverri","year":"2020","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2020.09.547_bib16","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1016\/j.jacc.2014.08.045","article-title":"Effect of atorvastatin therapy on fibrous cap thickness in coronary atherosclerotic plaque as assessed by optical coherence tomography: the EASY-FIT study","volume":"64","author":"Komukai","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2020.09.547_bib17","first-page":"996","article-title":"Long-term invasive follow-up of the everolimus-eluting bioresorbable vascular scaffold: five-year results of multiple invasive imaging modalities","volume":"11","author":"Simsek","year":"2016","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jacc.2020.09.547_bib18","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1016\/j.jcmg.2020.02.028","article-title":"Shear stress estimated by quantitative coronary angiography predicts plaques prone to progress and cause events","volume":"13","author":"Bourantas","year":"2020","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jacc.2020.09.547_bib19","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.jcmg.2017.01.031","article-title":"Role of low endothelial shear stress and plaque characteristics in the prediction of nonculprit major adverse cardiac events: the PROSPECT study","volume":"11","author":"Stone","year":"2018","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jacc.2020.09.547_bib20","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.jcin.2015.01.032","article-title":"Plaque characterization to inform the prediction and prevention of periprocedural myocardial infarction during percutaneous coronary intervention: the CANARY trial (Coronary Assessment by Near-infrared of Atherosclerotic Rupture-prone Yellow)","volume":"8","author":"Stone","year":"2015","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2020.09.547_bib21","doi-asserted-by":"crossref","first-page":"4112","DOI":"10.1093\/eurheartj\/ehy562","volume":"39","author":"Stone","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2020.09.547_bib22","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","article-title":"2019 ESC guidelines for the diagnosis and management of chronic coronary syndromes","volume":"41","author":"Knuuti","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2020.09.547_bib23","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1136\/hrt.2004.041798","article-title":"Pathologic assessment of the vulnerable human coronary plaque","volume":"90","author":"Kolodgie","year":"2004","journal-title":"Heart"},{"key":"10.1016\/j.jacc.2020.09.547_bib24","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1016\/j.jcin.2020.05.024","article-title":"Revascularization deferral of non-culprit stenoses based on fractional flow reserve: one-year outcomes of 8579 patients","volume":"13","author":"Cerrato","year":"2020","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2020.09.547_bib25","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1056\/NEJMoa1907775","article-title":"Complete revascularization with multivessel PCI for myocardial infarction","volume":"381","author":"Mehta","year":"2019","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2020.09.547_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcmg.2012.01.005","article-title":"Residual plaque burden in patients with acute coronary syndromes after successful percutaneous coronary intervention","volume":"5","author":"McPherson","year":"2012","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jacc.2020.09.547_bib27","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jcin.2019.09.047","article-title":"Randomized comparison between everolimus-eluting bioresorbable scaffold and metallic stent: multimodality imaging through 3 years","volume":"13","author":"Onuma","year":"2020","journal-title":"J\u00a0Am Coll Cardiol Intv"},{"key":"10.1016\/j.jacc.2020.09.547_bib28","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1056\/NEJMoa1614954","article-title":"Bioresorbable scaffolds versus metallic stents in routine PCI","volume":"376","author":"Wykrzykowska","year":"2017","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2020.09.547_bib29","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1001\/jamacardio.2019.4101","article-title":"Time-varying outcomes with the absorb bioresorbable vascular scaffold during 5-year follow-up: a systematic meta-analysis and individual patient data pooled study","volume":"4","author":"Stone","year":"2019","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jacc.2020.09.547_bib30","doi-asserted-by":"crossref","first-page":"2863","DOI":"10.1016\/j.jacc.2017.09.1106","article-title":"Effect of technique on outcomes following bioresorbable vascular scaffold implantation: analysis from the ABSORB trials","volume":"70","author":"Stone","year":"2017","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2020.09.547_bib31","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.4244\/EIJ-D-16-00247","article-title":"Clinical outcomes of a real-world cohort following bioresorbable vascular scaffold implantation utilising an optimised implantation strategy","volume":"12","author":"Tanaka","year":"2017","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jacc.2020.09.547_bib32","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.4244\/EIJ-D-16-00974","article-title":"Predilation, sizing and post-dilation scoring in\u00a0patients undergoing everolimus-eluting bioresorbable scaffold implantation for prediction of cardiac adverse events: development and internal validation of the PSP score","volume":"12","author":"Ortega-Paz","year":"2017","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jacc.2020.09.547_bib33","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1080\/14779072.2018.1473034","article-title":"Imaging-guided pre-dilatation, stenting, post-dilatation: a protocolized approach highlighting the importance of intravascular imaging for implantation of bioresorbable scaffolds","volume":"16","author":"Ali","year":"2018","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"10.1016\/j.jacc.2020.09.547_bib34","article-title":"Absorb bioresorbable vascular scaffold outcomes following implantation with routine intravascular imaging guidance","author":"Costantini","year":"2020","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jacc.2020.09.547_bib35","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.jacc.2006.09.047","article-title":"Selective clearance of macrophages in atherosclerotic plaques by autophagy","volume":"49","author":"Verheye","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109720372405?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109720372405?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:37:00Z","timestamp":1760017020000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109720372405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":35,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["S0735109720372405"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2020.09.547","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Percutaneous Coronary Intervention for Vulnerable Coronary Atherosclerotic Plaque","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2020.09.547","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}