{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T07:22:34Z","timestamp":1793604154774,"version":"4.5.0"},"reference-count":111,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T00:00:00Z","timestamp":1674000000000},"content-version":"vor","delay-in-days":382,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["119127"],"award-info":[{"award-number":["119127"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["1R01AG066914"],"award-info":[{"award-number":["1R01AG066914"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["1R01HL128914"],"award-info":[{"award-number":["1R01HL128914"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HL141434 01A1"],"award-info":[{"award-number":["HL141434 01A1"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01AG066010"],"award-info":[{"award-number":["R01AG066010"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL092577"],"award-info":[{"award-number":["R01HL092577"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000056","name":"National Institute of Nursing Research","doi-asserted-by":"publisher","award":["R01NR018443"],"award-info":[{"award-number":["R01NR018443"]}],"id":[{"id":"10.13039\/100000056","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["AHA_18SFRN34110082"],"award-info":[{"award-number":["AHA_18SFRN34110082"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001009","name":"Bristol-Myers Squibb Foundation","doi-asserted-by":"publisher","award":["1R01AG054476-01A1"],"award-info":[{"award-number":["1R01AG054476-01A1"]}],"id":[{"id":"10.13039\/100001009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001009","name":"Bristol-Myers Squibb Foundation","doi-asserted-by":"publisher","award":["1R01AG062637-01A1"],"award-info":[{"award-number":["1R01AG062637-01A1"]}],"id":[{"id":"10.13039\/100001009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001009","name":"Bristol-Myers Squibb Foundation","doi-asserted-by":"publisher","award":["P30AG010161"],"award-info":[{"award-number":["P30AG010161"]}],"id":[{"id":"10.13039\/100001009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001009","name":"Bristol-Myers Squibb Foundation","doi-asserted-by":"publisher","award":["R01 AG062689-02"],"award-info":[{"award-number":["R01 AG062689-02"]}],"id":[{"id":"10.13039\/100001009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001009","name":"Bristol-Myers Squibb Foundation","doi-asserted-by":"publisher","award":["R01AG 056653"],"award-info":[{"award-number":["R01AG 056653"]}],"id":[{"id":"10.13039\/100001009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001009","name":"Bristol-Myers Squibb Foundation","doi-asserted-by":"publisher","award":["R01AG051635"],"award-info":[{"award-number":["R01AG051635"]}],"id":[{"id":"10.13039\/100001009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001009","name":"Bristol-Myers Squibb Foundation","doi-asserted-by":"publisher","award":["U24AG057437"],"award-info":[{"award-number":["U24AG057437"]}],"id":[{"id":"10.13039\/100001009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","award":["CTQJ230A12001"],"award-info":[{"award-number":["CTQJ230A12001"]}],"id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.jacc.2021.10.037","type":"journal-article","created":{"date-parts":[[2022,1,10]],"date-time":"2022-01-10T20:42:16Z","timestamp":1641847336000},"page":"166-179","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":122,"title":["Management of Atrial Fibrillation in Patients 75 Years and Older"],"prefix":"10.1016","volume":"79","author":[{"given":"Annabelle Santos","family":"Volgman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gatha","family":"Nair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radmila","family":"Lyubarova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faisal M.","family":"Merchant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela","family":"Mason","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne B.","family":"Curtis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanette K.","family":"Wenger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neelum T.","family":"Aggarwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James N.","family":"Kirkpatrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emelia J.","family":"Benjamin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.jacc.2021.10.037_bib1","doi-asserted-by":"crossref","first-page":"e254","DOI":"10.1161\/CIR.0000000000000950","article-title":"Heart disease and stroke statistics-2021 update: a report from the American Heart Association","volume":"143","author":"Virani","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2021.10.037_bib2","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1001\/archinte.1995.00430050045005","article-title":"Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications","volume":"155","author":"Feinberg","year":"1995","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jacc.2021.10.037_bib3","doi-asserted-by":"crossref","first-page":"2982","DOI":"10.1016\/j.jacc.2020.11.010","article-title":"Global burden of cardiovascular diseases and risk factors, 1990-2019: update from the GBD 2019 Study","volume":"76","author":"Roth","year":"2020","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib4","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jacc.2019.01.011","volume":"74","author":"January","year":"2019","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib5","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1093\/europace\/euy117","article-title":"PREVEntion and regReSsive Effect of weight-loss and risk factor modification on Atrial Fibrillation: the REVERSE-AF study","volume":"20","author":"Middeldorp","year":"2018","journal-title":"Europace"},{"key":"10.1016\/j.jacc.2021.10.037_bib6","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.1001\/jama.2013.280521","article-title":"Effect of weight reduction and cardiometabolic risk factor management on symptom burden and severity in patients with atrial fibrillation: a randomized clinical trial","volume":"310","author":"Abed","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2021.10.037_bib7","unstructured":"ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). Identifier NCT03713775. LOSE-AF: can Weight Loss Help Patients With Atrial Fibrillation? 2018 (The Cochrane Controlled Trials Register (CCTR\/CENTRAL). Oxford: Update Software. Updated quarterly. Accessed September 17, 2021. https:\/\/ClinicalTrials.gov\/show\/NCT03713775"},{"key":"10.1016\/j.jacc.2021.10.037_bib8","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1056\/NEJMoa1817591","article-title":"Alcohol abstinence in drinkers with atrial fibrillation","volume":"382","author":"Voskoboinik","year":"2020","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2021.10.037_bib9","doi-asserted-by":"crossref","first-page":"4759","DOI":"10.1093\/eurheartj\/ehab315","article-title":"Lower risk of stroke after alcohol abstinence in patients with incident atrial fibrillation: a nationwide population-based cohort study","volume":"42","author":"Lee","year":"2021","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2021.10.037_bib10","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.ahj.2014.12.024","article-title":"Impact of obstructive sleep apnea and continuous positive airway pressure therapy on outcomes in patients with atrial fibrillation-Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)","volume":"169","author":"Holmqvist","year":"2015","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacc.2021.10.037_bib11","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1056\/NEJMoa1606599","article-title":"CPAP for prevention of cardiovascular events in obstructive sleep apnea","volume":"375","author":"McEvoy","year":"2016","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2021.10.037_bib12","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1161\/HYPERTENSIONAHA.120.14766","article-title":"Effect of intensive blood pressure lowering on the risk of atrial fibrillation","volume":"75","author":"Soliman","year":"2020","journal-title":"Hypertension"},{"key":"10.1016\/j.jacc.2021.10.037_bib13","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s12933-019-0983-1","article-title":"Risk of atrial fibrillation in persons with type 2 diabetes and the excess risk in relation to glycaemic control and renal function: a Swedish cohort study","volume":"19","author":"Seyed Ahmadi","year":"2020","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.jacc.2021.10.037_bib14","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/s12933-020-01105-5","article-title":"SGLT2 inhibitors and atrial fibrillation in type 2 diabetes: a systematic review with meta-analysis of 16 randomized controlled trials","volume":"19","author":"Li","year":"2020","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.jacc.2021.10.037_bib15","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.ijcard.2011.08.081","article-title":"Thiazolidinediones can prevent new onset atrial fibrillation in patients with non-insulin dependent diabetes","volume":"156","author":"Chao","year":"2012","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib16","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/s12933-014-0123-x","article-title":"Association of metformin with lower atrial fibrillation risk among patients with type 2 diabetes mellitus: a population-based dynamic cohort and in\u00a0vitro studies","volume":"13","author":"Chang","year":"2014","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.jacc.2021.10.037_bib17","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1161\/CIRCULATIONAHA.108.785626","article-title":"Physical activity and incidence of atrial fibrillation in older adults: the Cardiovascular Health Study","volume":"118","author":"Mozaffarian","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2021.10.037_bib18","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1093\/europace\/euw169","article-title":"Self-reported physical activity and major adverse events in patients with atrial fibrillation: a report from the EURObservational Research Programme Pilot Survey on Atrial Fibrillation (EORP-AF) General Registry","volume":"19","author":"Proietti","year":"2017","journal-title":"Europace"},{"key":"10.1016\/j.jacc.2021.10.037_bib19","doi-asserted-by":"crossref","first-page":"e750","DOI":"10.1161\/CIR.0000000000000748","article-title":"Lifestyle and risk factor modification for reduction of atrial fibrillation: a scientific statement from the American Heart Association","volume":"141","author":"Chung","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2021.10.037_bib20","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.jacc.2004.09.076","article-title":"Antiarrhythmic effect of carvedilol after acute myocardial infarction: results of the Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction (CAPRICORN) trial","volume":"45","author":"McMurray","year":"2005","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib21","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1177\/2047487317715769","article-title":"Atrial fibrillation and the risk for myocardial infarction, all-cause mortality and heart failure: a systematic review and meta-analysis","volume":"24","author":"Ruddox","year":"2017","journal-title":"Eur J Prev Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib22","article-title":"Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium","volume":"2","author":"Alonso","year":"2013","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jacc.2021.10.037_bib23","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1161\/CIRCULATIONAHA.110.986661","article-title":"Mortality associated with atrial fibrillation in patients with myocardial infarction: a systematic review and meta-analysis","volume":"123","author":"Jabre","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2021.10.037_bib24","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1161\/CIRCULATIONAHA.115.018614","article-title":"Atrial fibrillation begets heart failure and vice versa: temporal associations and differences in preserved versus reduced ejection fraction","volume":"133","author":"Santhanakrishnan","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2021.10.037_bib25","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1093\/eurheartj\/ehp222","article-title":"A\u00a0history of atrial fibrillation and outcomes in chronic advanced systolic heart failure: a propensity-matched study","volume":"30","author":"Ahmed","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2021.10.037_bib26","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.1161\/01.CIR.0000072767.89944.6E","article-title":"Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study","volume":"107","author":"Wang","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2021.10.037_bib27","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1093\/eurheartj\/ehl484","article-title":"Prevention of atrial fibrillation onset by beta-blocker treatment in heart failure: a meta-analysis","volume":"28","author":"Nasr","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2021.10.037_bib28","doi-asserted-by":"crossref","first-page":"2926","DOI":"10.1161\/01.CIR.0000072793.81076.D4","article-title":"Enalapril decreases the incidence of atrial fibrillation in patients with left ventricular dysfunction: insight from the Studies Of Left Ventricular Dysfunction (SOLVD) trials","volume":"107","author":"Vermes","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2021.10.037_bib29","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.ahj.2004.09.033","article-title":"Valsartan reduces the incidence of atrial fibrillation in patients with heart failure: results from the Valsartan Heart\u00a0Failure Trial (Val-HeFT)","volume":"149","author":"Maggioni","year":"2005","journal-title":"Am Heart J"},{"key":"10.1016\/j.jacc.2021.10.037_bib30","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1056\/NEJMoa1409077","article-title":"Angiotensin-neprilysin inhibition versus enalapril in heart failure","volume":"371","author":"McMurray","year":"2014","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2021.10.037_bib31","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1093\/eurheartj\/ehi115","article-title":"Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS)","volume":"26","author":"Flather","year":"2005","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2021.10.037_bib32","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.2215\/CJN.01860217","article-title":"eGFR and Albuminuria in relation to risk of incident atrial fibrillation: a meta-analysis of the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Cardiovascular Health Study","volume":"12","author":"Bansal","year":"2017","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.jacc.2021.10.037_bib33","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s40266-019-00722-4","article-title":"Clinical outcomes of rate vs rhythm control for atrial fibrillation in older people: a systematic review and meta-analysis","volume":"37","author":"Depoorter","year":"2020","journal-title":"Drugs Aging"},{"key":"10.1016\/j.jacc.2021.10.037_bib34","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s40266-018-0532-8","article-title":"Choice and outcomes of rate control versus rhythm control in elderly patients with atrial fibrillation: a report from the REPOSI Study","volume":"35","author":"Paciullo","year":"2018","journal-title":"Drugs Aging"},{"key":"10.1016\/j.jacc.2021.10.037_bib35","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1111\/jgs.16062","article-title":"Rate or rhythm control in older atrial fibrillation patients: risk of fall-related injuries and syncope","volume":"67","author":"Dalgaard","year":"2019","journal-title":"J\u00a0Am Geriatr Soc"},{"key":"10.1016\/j.jacc.2021.10.037_bib36","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.amjcard.2018.09.036","article-title":"Meta-analysis of effects of digoxin on survival in patients with atrial fibrillation or heart failure: an update","volume":"123","author":"Vamos","year":"2019","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib37","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/j.jacc.2017.12.060","article-title":"Digoxin and mortality in patients with atrial fibrillation","volume":"71","author":"Lopes","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib38","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1001\/jama.2020.23138","article-title":"Effect of digoxin vs bisoprolol for heart rate control in atrial fibrillation on patient-reported quality of life: the RATE-AF Randomized Clinical Trial","volume":"324","author":"Kotecha","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2021.10.037_bib39","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1001\/jama.2019.0693","article-title":"Effect of catheter ablation vs antiarrhythmic drug therapy on mortality, stroke, bleeding, and cardiac arrest among patients with atrial fibrillation: the CABANA Randomized Clinical Trial","volume":"321","author":"Packer","year":"2019","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2021.10.037_bib40","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.hrthm.2014.09.049","article-title":"Benefits and risks of catheter ablation in elderly patients with atrial fibrillation","volume":"12","author":"Nademanee","year":"2015","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacc.2021.10.037_bib41","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1111\/j.1540-8167.2008.01183.x","article-title":"Long-term clinical efficacy and risk of catheter ablation for atrial fibrillation in the elderly","volume":"19","author":"Zado","year":"2008","journal-title":"J\u00a0Cardiovasc Electrophysiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib42","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1111\/j.1540-8167.2012.02293.x","article-title":"Catheter ablation of atrial fibrillation in octogenarians: safety and outcomes","volume":"23","author":"Santangeli","year":"2012","journal-title":"J\u00a0Cardiovasc Electrophysiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib43","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1540-8159.2009.02604.x","article-title":"Long-term clinical efficacy and risk of catheter ablation for atrial fibrillation in octogenarians","volume":"33","author":"Bunch","year":"2010","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib44","doi-asserted-by":"crossref","first-page":"2200","DOI":"10.1161\/CIRCULATIONAHA.112.109330","article-title":"Outcomes of Medicare beneficiaries undergoing catheter ablation for atrial fibrillation","volume":"126","author":"Piccini","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2021.10.037_bib45","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.hrthm.2018.12.019","article-title":"Propensity-matched comparison of cryoballoon and radiofrequency ablation for atrial fibrillation in elderly patients","volume":"16","author":"Ikenouchi","year":"2019","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.jacc.2021.10.037_bib46","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1016\/j.jacc.2018.03.019","article-title":"Arrhythmias in Patients\u00a0\u226580 Years of Age: Pathophysiology, Management, and Outcomes","volume":"71","author":"Curtis","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib47","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1007\/s00392-019-01471-5","article-title":"Procedural success, safety and patients satisfaction after second ablation of atrial fibrillation in the elderly: results from the German Ablation Registry","volume":"108","author":"Fink","year":"2019","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib48","doi-asserted-by":"crossref","first-page":"3999","DOI":"10.1093\/eurheartj\/ehy555","article-title":"A\u00a0randomized controlled trial of atrioventricular junction ablation and cardiac resynchronization therapy in patients with permanent atrial fibrillation and narrow QRS","volume":"39","author":"Brignole","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2021.10.037_bib49","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1111\/pace.14223","article-title":"Arrhythmia profile and ablation-outcome in elderly women with atrial fibrillation undergoing first catheter ablation","volume":"44","author":"Natale","year":"2021","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib50","first-page":"626","article-title":"Efficacy and safety of the second-generation cryoballoon ablation for the treatment of persistent atrial fibrillation in elderly patients","volume":"37","author":"Vermeersch","year":"2021","journal-title":"J\u00a0Arrhythm"},{"key":"10.1016\/j.jacc.2021.10.037_bib51","first-page":"149","article-title":"Opportunistic screening for atrial fibrillation with a single lead device in geriatric patients","volume":"17","author":"Zwart","year":"2020","journal-title":"J\u00a0Geriatr Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib52","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1093\/europace\/euaa190","article-title":"Screen-detected atrial fibrillation predicts mortality in elderly subjects","volume":"23","author":"Zink","year":"2021","journal-title":"Europace"},{"key":"10.1016\/j.jacc.2021.10.037_bib53","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1161\/CIRCULATIONAHA.120.047633","article-title":"Research Priorities in Atrial Fibrillation Screening: A Report From a National Heart, Lung, and Blood Institute Virtual Workshop","volume":"143","author":"Benjamin","year":"2021","journal-title":"Circulation"},{"issue":"10310","key":"10.1016\/j.jacc.2021.10.037_bib54","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1016\/S0140-6736(21)01698-6","article-title":"Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial","volume":"398","author":"Svendsen","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2021.10.037_bib55","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s40256-020-00457-3","article-title":"Non-adherence to thromboprophylaxis guidelines in atrial fibrillation: a narrative review of the extent of and factors in guideline non-adherence","volume":"21","author":"Gebreyohannes","year":"2021","journal-title":"Am J Cardiovasc Drugs"},{"key":"10.1016\/j.jacc.2021.10.037_bib56","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s11239-019-01937-3","article-title":"Determinants of anticoagulant therapy in atrial fibrillation at discharge from a geriatric ward: cross sectional study","volume":"49","author":"Wojszel","year":"2020","journal-title":"J\u00a0Thromb Thrombolysis"},{"key":"10.1016\/j.jacc.2021.10.037_bib57","doi-asserted-by":"crossref","first-page":"223","DOI":"10.2174\/157488610791698253","article-title":"Contraindications for anticoagulation in older patients with atrial fibrillation; a narrative review","volume":"5","author":"Tulner","year":"2010","journal-title":"Curr Drug Saf"},{"key":"10.1016\/j.jacc.2021.10.037_bib58","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.2146\/ajhp160756","article-title":"Trends in utilization of warfarin and direct oral anticoagulants in older adult patients with atrial fibrillation","volume":"74","author":"Alalwan","year":"2017","journal-title":"Am J Health Syst Pharm"},{"key":"10.1016\/j.jacc.2021.10.037_bib59","doi-asserted-by":"crossref","first-page":"2524","DOI":"10.1111\/bcp.14071","article-title":"Incidence of direct oral anticoagulant use in patients with nonvalvular atrial fibrillation and characteristics of users in 6 European countries (2008-2015): A cross-national drug utilization study","volume":"85","author":"Ib\u00e1\u00f1ez","year":"2019","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.jacc.2021.10.037_bib60","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1002\/phar.2158","article-title":"Trends and variation in oral anticoagulant choice in patients with atrial fibrillation, 2010-2017","volume":"38","author":"Zhu","year":"2018","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.jacc.2021.10.037_bib61","doi-asserted-by":"crossref","first-page":"749","DOI":"10.2147\/CIA.S159373","article-title":"Hospitalized frail elderly patients - atrial fibrillation, anticoagulation and 12\u00a0months' outcomes","volume":"13","author":"Ekerstad","year":"2018","journal-title":"Clin Interv Aging"},{"key":"10.1016\/j.jacc.2021.10.037_bib62","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1093\/eurheartj\/eht483","article-title":"Clinical course of atrial fibrillation in older adults: the importance of cardiovascular events beyond stroke","volume":"35","author":"Piccini","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2021.10.037_bib63","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1001\/jamainternmed.2021.1819","article-title":"Anticoagulant use for atrial fibrillation among persons with advanced dementia at the end of life","volume":"181","author":"Ouellet","year":"2021","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.jacc.2021.10.037_bib64","doi-asserted-by":"crossref","first-page":"O14","DOI":"10.1093\/eurheartj\/suaa178","article-title":"Stroke and bleeding risk stratification in atrial fibrillation: a critical appraisal","volume":"22","author":"Lane","year":"2020","journal-title":"Eur Heart J Suppl"},{"key":"10.1016\/j.jacc.2021.10.037_bib65","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/eurheartj\/ehaa612","volume":"42","author":"Hindricks","year":"2021","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2021.10.037_bib66","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.amjmed.2014.05.003","article-title":"Stroke and bleeding risk co-distribution in real-world patients with atrial fibrillation: the Euro Heart Survey","volume":"127","author":"Marcucci","year":"2014","journal-title":"Am J Med"},{"key":"10.1016\/j.jacc.2021.10.037_bib67","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-017157","article-title":"Improved risk stratification of patients with atrial fibrillation: an integrated GARFIELD-AF tool for the prediction of mortality, stroke and bleed in patients with and without anticoagulation","volume":"7","author":"Fox","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.jacc.2021.10.037_bib68","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1161\/STROKEAHA.114.007199","article-title":"Stroke and major bleeding risk in elderly patients aged\u00a0\u226575 years with atrial fibrillation: the Loire Valley atrial fibrillation project","volume":"46","author":"Lip","year":"2015","journal-title":"Stroke"},{"key":"10.1016\/j.jacc.2021.10.037_bib69","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/S0140-6736(13)62343-0","article-title":"Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials","volume":"383","author":"Ruff","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2021.10.037_bib70","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1007\/s11606-020-05777-3","article-title":"Comparative Safety and effectiveness of direct-acting oral anticoagulants versus warfarin: a national cohort study of nursing home residents","volume":"35","author":"Alcusky","year":"2020","journal-title":"J\u00a0Gen Intern Med"},{"key":"10.1016\/j.jacc.2021.10.037_bib71","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0213614","article-title":"Effectiveness and safety of oral anticoagulants in older adults with non-valvular atrial fibrillation and heart failure","volume":"14","author":"Amin","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.jacc.2021.10.037_bib72","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1016\/j.amjcard.2019.02.060","article-title":"Meta-analysis of direct-acting oral anticoagulants compared with warfarin in patients >75 years of age","volume":"123","author":"Malik","year":"2019","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib73","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1016\/j.amjcard.2020.02.028","article-title":"Comparing major bleeding risk in outpatients with atrial fibrillation or flutter by oral anticoagulant type (from the National Cardiovascular Disease Registry's Practice Innovation and Clinical Excellence Registry)","volume":"125","author":"Wong","year":"2020","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib74","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7326\/M19-3671","article-title":"Association between treatment with apixaban, dabigatran, rivaroxaban, or warfarin and risk for osteoporotic fractures among patients with atrial fibrillation: a population-based cohort study","volume":"173","author":"Lau","year":"2020","journal-title":"Ann Intern Med"},{"issue":"9","key":"10.1016\/j.jacc.2021.10.037_bib75","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.7326\/M20-7141","article-title":"Frailty and clinical outcomes of direct oral anticoagulants versus warfarin in older adults with atrial fibrillation: a cohort study","volume":"174","author":"Kim","year":"2021","journal-title":"Ann Intern Med"},{"issue":"2","key":"10.1016\/j.jacc.2021.10.037_bib76","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2021-001737","article-title":"Anticoagulation trends in adults aged 65 years and over with atrial fibrillation: a cohort study","volume":"8","author":"Lund","year":"2021","journal-title":"Open Heart"},{"key":"10.1016\/j.jacc.2021.10.037_bib77","first-page":"353","article-title":"Apixaban in patients with atrial fibrillation and severe renal dysfunction: findings from a national registry","volume":"23","author":"Elis","year":"2021","journal-title":"Isr Med Assoc J"},{"key":"10.1016\/j.jacc.2021.10.037_bib78","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1056\/NEJMoa2012883","article-title":"Low-dose edoxaban in very elderly patients with atrial fibrillation","volume":"383","author":"Okumura","year":"2020","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2021.10.037_bib79","article-title":"Management of atrial fibrillation in older patients by morbidity burden: insights from Get With The Guidelines-Atrial Fibrillation","volume":"9","author":"Dalgaard","year":"2020","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jacc.2021.10.037_bib80","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1001\/archinte.159.7.677","article-title":"Choosing antithrombotic therapy for elderly patients with atrial fibrillation who are at risk for falls","volume":"159","author":"Man-Son-Hing","year":"1999","journal-title":"Arch Intern Med"},{"issue":"8","key":"10.1016\/j.jacc.2021.10.037_bib81","article-title":"Effectiveness and safety of apixaban, dabigatran, and rivaroxaban versus warfarin in frail patients with nonvalvular atrial fibrillation","volume":"7","author":"Martinez","year":"2018","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jacc.2021.10.037_bib82","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.amjmed.2017.10.036","article-title":"Clinical outcomes and history of fall in patients with atrial fibrillation treated with oral anticoagulation: insights from the ARISTOTLE Trial","volume":"131","author":"Rao","year":"2018","journal-title":"Am J Med"},{"key":"10.1016\/j.jacc.2021.10.037_bib83","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/j.jacc.2016.06.034","article-title":"Edoxaban versus warfarin in atrial fibrillation patients at risk of falling: ENGAGE AF-TIMI 48 Analysis","volume":"68","author":"Steffel","year":"2016","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib84","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1007\/s40266-021-00870-6","article-title":"Impact of fall risk and direct oral anticoagulant treatment on quality-adjusted life-years in older adults with atrial fibrillation: a Markov Decision Analysis","volume":"38","author":"Wei","year":"2021","journal-title":"Drugs Aging"},{"key":"10.1016\/j.jacc.2021.10.037_bib85","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.thromres.2016.10.006","article-title":"Cost-effectiveness of non-vitamin K antagonist oral anticoagulants for stroke prevention in patients with atrial fibrillation at high risk of bleeding and normal kidney function","volume":"150","author":"Hernandez","year":"2017","journal-title":"Thromb Res"},{"key":"10.1016\/j.jacc.2021.10.037_bib86","doi-asserted-by":"crossref","first-page":"j5058","DOI":"10.1136\/bmj.j5058","article-title":"Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis","volume":"359","author":"L\u00f3pez-L\u00f3pez","year":"2017","journal-title":"BMJ"},{"key":"10.1016\/j.jacc.2021.10.037_bib87","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1161\/STROKEAHA.111.000402","article-title":"Cost-effectiveness of apixaban, dabigatran, rivaroxaban, and warfarin for stroke prevention in atrial fibrillation","volume":"44","author":"Harrington","year":"2013","journal-title":"Stroke"},{"key":"10.1016\/j.jacc.2021.10.037_bib88","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.ijcard.2016.06.087","article-title":"Cost-effectiveness modelling of novel oral anticoagulants incorporating real-world elderly patients with atrial fibrillation","volume":"220","author":"Zhao","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib89","doi-asserted-by":"crossref","first-page":"745","DOI":"10.2147\/CEOR.S317078","article-title":"Cost-effectiveness of apixaban versus other direct oral anticoagulants and warfarin in the prevention of thromboembolic complications among Finnish patients with non-valvular atrial fibrillation","volume":"13","author":"Hallinen","year":"2021","journal-title":"Clinicoecon Outcomes Res"},{"key":"10.1016\/j.jacc.2021.10.037_bib90","first-page":"911","article-title":"A\u00a0Real-world observational study of hospitalization and health care costs among nonvalvular atrial fibrillation patients prescribed oral anticoagulants in the U.S. Medicare Population","volume":"24","author":"Amin","year":"2018","journal-title":"J\u00a0Manag Care Spec Pharm"},{"key":"10.1016\/j.jacc.2021.10.037_bib91","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.thromres.2019.07.026","article-title":"Healthcare resource utilization and costs among patients with direct oral anticoagulant or warfarin-related major bleeding","volume":"182","author":"Xu","year":"2019","journal-title":"Thromb Res"},{"key":"10.1016\/j.jacc.2021.10.037_bib92","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1080\/03007995.2017.1345729","article-title":"Risk of stroke\/systemic embolism, major bleeding and associated costs in non-valvular atrial fibrillation patients who initiated apixaban, dabigatran or rivaroxaban compared with warfarin in the United States Medicare population","volume":"33","author":"Amin","year":"2017","journal-title":"Curr Med Res Opin"},{"key":"10.1016\/j.jacc.2021.10.037_bib93","doi-asserted-by":"crossref","first-page":"2844","DOI":"10.1161\/STROKEAHA.118.022596","article-title":"Anticoagulation Therapy for Atrial Fibrillation in Patients With Alzheimer's Disease","volume":"49","author":"Ruiz Vargas","year":"2018","journal-title":"Stroke"},{"key":"10.1016\/j.jacc.2021.10.037_bib94","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jacc.2014.04.029","article-title":"Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial","volume":"64","author":"Holmes","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib96","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.amjcard.2020.09.017","article-title":"Comparison in patients\u00a0< 75 years of age - versus - those > 75 years on one-year-events with atrial fibrillation and left atrial appendage occluder (from the Prospective Multicenter German LAARGE Registry)","volume":"136","author":"Nasasra","year":"2020","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib97","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1007\/s00380-019-01428-8","article-title":"Efficacy and safety of left atrial appendage closure in non-valvular atrial fibrillation in patients over 75 years","volume":"34","author":"Yu","year":"2019","journal-title":"Heart Vessels"},{"key":"10.1016\/j.jacc.2021.10.037_bib98","first-page":"51","article-title":"Is dual therapy the correct strategy in frail elderly patients with atrial fibrillation and acute coronary syndrome?","volume":"17","author":"Menditto","year":"2020","journal-title":"J\u00a0Geriatr Cardiol"},{"key":"10.1016\/j.jacc.2021.10.037_bib99","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.ccl.2020.07.006","article-title":"Antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention","volume":"38","author":"Camaj","year":"2020","journal-title":"Cardiol Clin"},{"key":"10.1016\/j.jacc.2021.10.037_bib100","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1111\/ggi.14242","article-title":"Relationship between number of medications and incidence of falls or bone fracture in elderly patients with non-valvular atrial fibrillation: Shinken database analysis","volume":"21","author":"Fujisawa","year":"2021","journal-title":"Geriatr Gerontol Int"},{"key":"10.1016\/j.jacc.2021.10.037_bib101","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1093\/eurheartj\/ehz386","article-title":"Risk of dementia in stroke-free patients diagnosed with atrial fibrillation: data from a population-based cohort","volume":"40","author":"Kim","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2021.10.037_bib102","doi-asserted-by":"crossref","first-page":"e1732","DOI":"10.1212\/WNL.0000000000006456","article-title":"Atrial fibrillation, antithrombotic treatment, and cognitive aging: a population-based study","volume":"91","author":"Ding","year":"2018","journal-title":"Neurology"},{"key":"10.1016\/j.jacc.2021.10.037_bib103","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1093\/europace\/eux031","article-title":"Does atrial fibrillation cause cognitive decline and dementia?","volume":"20","author":"Dietzel","year":"2018","journal-title":"Europace"},{"key":"10.1016\/j.jacc.2021.10.037_bib104","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/joim.12902","article-title":"Atrial fibrillation increases the risk of dementia amongst older adults even in the absence of stroke","volume":"286","author":"Ryd\u00e9n","year":"2019","journal-title":"J\u00a0Intern Med"},{"key":"10.1016\/j.jacc.2021.10.037_bib105","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.ejim.2017.08.010","article-title":"Relationship between atrial fibrillation and cognitive decline in individuals aged 80 and older","volume":"46","author":"Proietti","year":"2017","journal-title":"Eur J Intern Med"},{"issue":"11","key":"10.1016\/j.jacc.2021.10.037_bib106","doi-asserted-by":"crossref","first-page":"3459","DOI":"10.1161\/STROKEAHA.120.033338","article-title":"Comparing warfarin and 4 direct oral anticoagulants for the risk of dementia in patients with atrial fibrillation","volume":"52","author":"Lee","year":"2021","journal-title":"Stroke"},{"key":"10.1016\/j.jacc.2021.10.037_bib108","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1159\/000506923","article-title":"Rates and determinants for the use of anticoagulation treatment before stroke in patients with known atrial fibrillation","volume":"10","author":"Giustozzi","year":"2020","journal-title":"Cerebrovasc Dis Extra"},{"key":"10.1016\/j.jacc.2021.10.037_bib109","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1161\/STROKEAHA.120.030138","article-title":"Initial stroke severity in patients with atrial fibrillation according to antithrombotic therapy before ischemic stroke","volume":"51","author":"Jung","year":"2020","journal-title":"Stroke"},{"key":"10.1016\/j.jacc.2021.10.037_bib113","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1001\/jama.2018.3097","article-title":"Interventions to prevent falls in community-dwelling older adults: US Preventive Services Task Force recommendation statement","volume":"319","author":"Grossman","year":"2018","journal-title":"JAMA"},{"key":"10.1016\/j.jacc.2021.10.037_bib114","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2018.8280","article-title":"Effectiveness of tai ji quan vs multimodal and stretching exercise interventions for reducing injurious falls in older adults at high risk of falling: follow-up analysis of a randomized clinical trial","volume":"2","author":"Li","year":"2019","journal-title":"JAMA Network Open"},{"issue":"1","key":"10.1016\/j.jacc.2021.10.037_bib115","first-page":"CD012424","article-title":"Exercise for preventing falls in older people living in the community","volume":"1","author":"Sherrington","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jacc.2021.10.037_bib116","first-page":"739","article-title":"Under-reporting and under-representation of racial\/ethnic minorities in major atrial fibrillation clinical trials","volume":"6","author":"Sarraju","year":"2020","journal-title":"J\u00a0Am Coll Cardiol EP"}],"updated-by":[{"DOI":"10.1016\/j.jacc.2022.03.362","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T00:00:00Z","timestamp":1652745600000}}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109721081419?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109721081419?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T07:07:17Z","timestamp":1722323237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109721081419"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":111,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["S0735109721081419"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2021.10.037","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.jacc.2022.03.362","asserted-by":"object"}]},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Management of Atrial Fibrillation in Patients 75 Years and Older","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2021.10.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}