{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:45:29Z","timestamp":1789155929457,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","issue":"23","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T00:00:00Z","timestamp":1686700800000},"content-version":"vor","delay-in-days":378,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.jacc.2022.03.357","type":"journal-article","created":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T08:28:30Z","timestamp":1648888110000},"page":"2325-2330","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":97,"title":["Prospective Evaluation of Autonomic\u00a0Dysfunction in Post-Acute Sequela of COVID-19"],"prefix":"10.1016","volume":"79","author":[{"given":"Sameer M.","family":"Jamal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David B.","family":"Landers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1293-8496","authenticated-orcid":false,"given":"Steven M.","family":"Hollenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoltan G.","family":"Turi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taya V.","family":"Glotzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Tancredi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph E.","family":"Parrillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2022.03.357_bib1","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/s41591-021-01283-z","article-title":"Post-acute COVID-19 syndrome","volume":"27","author":"Nalbandian","year":"2021","journal-title":"Nat Med"},{"issue":"7","key":"10.1016\/j.jacc.2022.03.357_bib2","doi-asserted-by":"crossref","first-page":"999","DOI":"10.7326\/M21-1043","article-title":"Toward understanding COVID-19 recovery: National Institutes of Health Workshop on Postacute COVID-19","volume":"174","author":"Lerner","year":"2021","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jacc.2022.03.357_bib3","doi-asserted-by":"crossref","first-page":"6571","DOI":"10.1038\/s41467-021-26513-3","article-title":"Burdens of post-acute sequelae of COVID-19 by severity of acute infection, demographics and health status. Burdens of post-acute sequelae of COVID-19 by severity of acute infection, demographics and health status","volume":"12","author":"Xie","year":"2021","journal-title":"Nat Commun"},{"key":"10.1016\/j.jacc.2022.03.357_bib4","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S0140-6736(20)32656-8","article-title":"6-month consequences of COVID-19 in patients discharged from hospital: a cohort study","volume":"397","author":"Huang","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.jacc.2022.03.357_bib5","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.cmi.2020.09.052","article-title":"Follow-up of adults with noncritical COVID-19 two months after symptom onset","volume":"27","author":"Carvalho-Schneider","year":"2021","journal-title":"Clin Microbiol Infect"},{"issue":"5","key":"10.1016\/j.jacc.2022.03.357_bib6","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s10286-020-00727-9","article-title":"A\u00a0case report of postural tachycardia syndrome after COVID-19","volume":"30","author":"Miglis","year":"2020","journal-title":"Clin Auton Res"},{"issue":"6","key":"10.1016\/j.jacc.2022.03.357_bib7","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s10286-020-00733-x","article-title":"Acute hyperhidrosis and postural tachycardia in a COVID-19 patient","volume":"30","author":"Umapathi","year":"2020","journal-title":"Clin Auton Res"},{"issue":"11","key":"10.1016\/j.jacc.2022.03.357_bib8","doi-asserted-by":"crossref","first-page":"4302","DOI":"10.19102\/icrm.2020.111102","article-title":"New-onset postural orthostatic tachycardia syndrome following Coronavirus disease 2019 infection","volume":"11","author":"Kanjwal","year":"2020","journal-title":"J\u00a0Innov Cardiac Rhythm Manage"},{"issue":"4","key":"10.1016\/j.jacc.2022.03.357_bib9","first-page":"573","article-title":"Long-haul post-COVID-19 symptoms presenting as a variant of a postural orthostatic tachycardia syndrome: the Swedish experience","volume":"3","author":"Johansson","year":"2021","journal-title":"J\u00a0Am Coll Cardiol Case Rep"},{"issue":"2","key":"10.1016\/j.jacc.2022.03.357_bib10","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s12026-021-09185-5","article-title":"Postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders after COVID-19 infection: a case series of 20 patients","volume":"69","author":"Blitshteyn","year":"2021","journal-title":"Immunol Res"},{"issue":"4","key":"10.1016\/j.jacc.2022.03.357_bib11","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1053\/eupc.2000.0125","article-title":"'The Italian Protocol': a simplified head-up tilt testing potentiated with oral nitroglycerin to assess patients with unexplained syncope","volume":"2","author":"Bartoletti","year":"2000","journal-title":"Europace"},{"key":"10.1016\/j.jacc.2022.03.357_bib12","series-title":"Chapter 7. Tilt Table Testing. Syncope: Mechanisms and Management","first-page":"76","author":"Grubb","year":"2008"},{"key":"10.1016\/j.jacc.2022.03.357_bib13","first-page":"397","article-title":"Syncope in children and adolescents","volume":"33","author":"Kanjwal","year":"2015","journal-title":"CardiolClin"},{"key":"10.1016\/j.jacc.2022.03.357_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1540-8167.2005.00318.x","article-title":"The postural tachycardia syndrome: as concise guide to diagnosis and management","volume":"17","author":"Grubb","year":"2006","journal-title":"J\u00a0Cardiovasc Electrophysiol"},{"key":"10.1016\/j.jacc.2022.03.357_bib15","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/j.jacc.2018.11.059","article-title":"Postural orthostatic tachycardia syndrome. JACC Focus Seminar","volume":"73","author":"Bryarly","year":"2019","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.jacc.2022.03.357_bib16","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0002-9149(99)80079-4","article-title":"Value of head-up testing potentiated with sublingual nitroglycerine to assess the origin of unexplained syncope","volume":"76","author":"Raviele","year":"1995","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2022.03.357_bib17","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.jacc.2004.04.038","article-title":"Sublingual nitroglycerine used in routine tilt testing provokes a cardiac output-mediated vasovagal response","volume":"44","author":"Gisolf","year":"2004","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.jacc.2022.03.357_bib18","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/S0002-9149(99)00413-0","article-title":"Usefulness of tilt test\u2013induced patterns of heart rate and blood pressure using a two-stage protocol with glyceryl trinitrate provocation in patients with syncope of unknown origin","volume":"84","author":"Kurbaan","year":"1999","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jacc.2022.03.357_bib19","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/S0025-6196(11)61027-6","article-title":"Postural orthostatic tachycardia syndrome: the Mayo Clinic experience","volume":"82","author":"Thieben","year":"2007","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.jacc.2022.03.357_bib20","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1212\/WNL.43.1_Part_1.132","article-title":"Idiopathic postural orthostatic tachycardia syndrome: an attenuated form of acute pandysautonomia?","volume":"43","author":"Schondorf","year":"1993","journal-title":"Neurology"},{"key":"10.1016\/j.jacc.2022.03.357_bib21","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.amjmed.2009.09.018","article-title":"Orthostatic syndromes differ in syncope frequency","volume":"123","author":"Ojha","year":"2010","journal-title":"Am J Med"},{"key":"10.1016\/j.jacc.2022.03.357_bib22","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1111\/pace.13441","article-title":"Role of implantable loop recorders in patients with postural orthostatic tachycardia syndrome","volume":"41","author":"Kanjwal","year":"2018","journal-title":"Pacing Clin Electrophysiol"},{"issue":"1","key":"10.1016\/j.jacc.2022.03.357_bib23","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3934\/Neuroscience.2021004","article-title":"Postural orthostatic tachycardia syndrome in patients of orthostatic intolerance symptoms: an ambispective study","volume":"8","author":"Chouksey","year":"2020","journal-title":"AIMS Neurosci"},{"issue":"2","key":"10.1016\/j.jacc.2022.03.357_bib24","first-page":"84","article-title":"The Postural Tachycardia Syndrome (POTS): pathophysiology, diagnosis & management","volume":"6","author":"Raj","year":"2006","journal-title":"Indian Pacing Electrophysiol J"},{"issue":"5","key":"10.1016\/j.jacc.2022.03.357_bib25","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1111\/j.1540-8159.2010.02994.x","article-title":"Neurocardiogenic syncope coexisting with postural orthostatic tachycardia syndrome in patients suffering from orthostatic intolerance: a combined form of autonomic dysfunction","volume":"34","author":"Kanjwal","year":"2011","journal-title":"Pacing Clin Electrophysiol"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109722045818?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109722045818?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:50:18Z","timestamp":1760017818000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109722045818"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":25,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["S0735109722045818"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2022.03.357","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prospective Evaluation of Autonomic\u00a0Dysfunction in Post-Acute Sequela of COVID-19","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2022.03.357","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}