{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T07:03:42Z","timestamp":1791529422140,"version":"4.3.4"},"reference-count":34,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T00:00:00Z","timestamp":1693958400000},"content-version":"vor","delay-in-days":370,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jacc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.jacc.2022.06.022","type":"journal-article","created":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T15:01:24Z","timestamp":1661785284000},"page":"982-994","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Validated Model for Prediction of Adverse Cardiac Outcome in Patients With Fabry Disease"],"prefix":"10.1016","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9514-110X","authenticated-orcid":false,"given":"Christopher","family":"Orsborne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Bradley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura J.","family":"Bonnett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke A.","family":"Pleva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josephine H.","family":"Naish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David G.","family":"Clark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nik","family":"Abidin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Woolfson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano","family":"Nucifora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Schmitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Jovanovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher A.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna B.","family":"Reid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.jacc.2022.06.022_bib1","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1136\/jmg.2008.065904","article-title":"Natural course of Fabry disease: changing pattern of causes of death in FOS","volume":"46","author":"Mehta","year":"2009","journal-title":"J\u00a0Med Genet"},{"issue":"6","key":"10.1016\/j.jacc.2022.06.022_bib2","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1136\/heartjnl-2018-313699","article-title":"Global longitudinal strain, myocardial storage and hypertrophy in Fabry disease","volume":"105","author":"Vijapurapu","year":"2019","journal-title":"Heart"},{"issue":"2","key":"10.1016\/j.jacc.2022.06.022_bib3","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)","volume":"42","author":"Harris","year":"2009","journal-title":"J\u00a0Biomed Inform"},{"issue":"12","key":"10.1016\/j.jacc.2022.06.022_bib4","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1136\/heartjnl-2014-306782","article-title":"Clinical and genetic predictors of major cardiac events in\u00a0patients with Anderson\u2013Fabry Disease","volume":"101","author":"Patel","year":"2015","journal-title":"Heart"},{"issue":"1","key":"10.1016\/j.jacc.2022.06.022_bib5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s12968-020-00610-6","article-title":"Standardized image interpretation and post-processing in CMR","volume":"22","author":"Schulz-Menger","year":"2020","journal-title":"J\u00a0Cardiovasc Magn Reson"},{"issue":"3","key":"10.1016\/j.jacc.2022.06.022_bib6","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1080\/10976640600572889","article-title":"Normalized left ventricular systolic and diastolic function by steady state free precession CMR","volume":"8","author":"Maceira","year":"2006","journal-title":"J\u00a0Cardiovasc Magn Reson"},{"key":"10.1016\/j.jacc.2022.06.022_bib7","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/s12968-015-0152-y","article-title":"Left atrial structure and functional quantitation using CMR and multimodality tissue tracking","volume":"17","author":"Zareian","year":"2015","journal-title":"J\u00a0Cardiovasc Magn Reson"},{"issue":"11","key":"10.1016\/j.jacc.2022.06.022_bib8","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.119.009404","article-title":"Prognostic implications of global longitudinal strain by feature-tracking cardiac magnetic resonance in ST-elevation myocardial infarction","volume":"12","author":"Reindl","year":"2019","journal-title":"Circ Cardiovasc Imaging"},{"issue":"1","key":"10.1016\/j.jacc.2022.06.022_bib9","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s12968-017-0389-8","article-title":"Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2\u2217 and extracellular volume","volume":"19","author":"Messroghli","year":"2017","journal-title":"J\u00a0Cardiovasc Magn Reson"},{"issue":"3","key":"10.1016\/j.jacc.2022.06.022_bib10","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1161\/CIRCIMAGING.112.000192","article-title":"Comprehensive validation of cardiovascular magnetic resonance techniques for the assessment of myocardial extracellular volume","volume":"6","author":"Miller","year":"2013","journal-title":"Circ Cardiovasc Imaging"},{"issue":"13","key":"10.1016\/j.jacc.2022.06.022_bib11","first-page":"e272","article-title":"Guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death","volume":"138","author":"Al-Khatib","year":"2018","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.jacc.2022.06.022_bib12","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/eurheartj\/ehaa612","article-title":"ESC guidelines for the diagnosis and management of atrial fibrillation","volume":"42","author":"Hindricks","year":"2021","journal-title":"Eur Heart J"},{"issue":"2","key":"10.1016\/j.jacc.2022.06.022_bib13","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1161\/CIRCULATIONAHA.114.014508","article-title":"Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis","volume":"131","author":"Collins","year":"2015","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.jacc.2022.06.022_bib14","first-page":"1","article-title":"Multivariate imputation by chained equations in R","volume":"45","author":"van Buuren","year":"2011","journal-title":"J\u00a0Stat Softw"},{"key":"10.1016\/j.jacc.2022.06.022_bib15","series-title":"Regression Modeling Strategies","author":"Harrell","year":"2015"},{"issue":"2","key":"10.1016\/j.jacc.2022.06.022_bib16","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/1467-9868.00125","article-title":"Smoothing parameter selection in nonparametric regression using an improved Akaike information criterion","volume":"60","author":"Hurvich","year":"1998","journal-title":"J\u00a0R Stat Soc"},{"key":"10.1016\/j.jacc.2022.06.022_bib17","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/1471-2288-9-57","article-title":"Combining estimates of interest in prognostic modelling studies after multiple imputation","volume":"9","author":"Marshall","year":"2009","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.jacc.2022.06.022_bib18","series-title":"Flexible Imputation of Missing Data","author":"van Buuren","year":"2018"},{"issue":"21","key":"10.1016\/j.jacc.2022.06.022_bib19","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1002\/sim.8570","article-title":"Graphical calibration curves and the integrated calibration index for survival models","volume":"39","author":"Austin","year":"2020","journal-title":"Stat Med"},{"key":"10.1016\/j.jacc.2022.06.022_bib20","series-title":"Multiple Imputation for Nonresponse in Surveys","author":"Rubin","year":"1987"},{"issue":"4","key":"10.1016\/j.jacc.2022.06.022_bib21","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.ymgme.2018.02.014","article-title":"Fabry disease revisited: management and treatment recommendations for adult patients","volume":"123","author":"Ortiz","year":"2018","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.jacc.2022.06.022_bib22","author":"Hiwot"},{"key":"10.1016\/j.jacc.2022.06.022_bib23","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s13023-015-0253-6","article-title":"Recommendations for initiation and cessation of\u00a0enzyme replacement therapy in patients with Fabry disease","volume":"10","author":"Biegstraaten","year":"2015","journal-title":"Orphanet J Rare Dis"},{"issue":"30","key":"10.1016\/j.jacc.2022.06.022_bib24","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1093\/eurheartj\/eht439","article-title":"A\u00a0novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy","volume":"35","author":"O'Mahony","year":"2014","journal-title":"Eur Heart J"},{"issue":"11 Pt 2","key":"10.1016\/j.jacc.2022.06.022_bib25","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1016\/j.jcmg.2019.06.031","article-title":"Myocardial T1 and ECV measurement: underlying concepts and technical considerations","volume":"12","author":"Robinson","year":"2019","journal-title":"J\u00a0Am Coll Cardiol Img"},{"issue":"3","key":"10.1016\/j.jacc.2022.06.022_bib26","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1136\/jmedgenet-2011-100407","article-title":"Fabry International Prognostic Index: a predictive severity score for Anderson-Fabry disease","volume":"49","author":"Hughes","year":"2012","journal-title":"J\u00a0Med Genet"},{"issue":"9","key":"10.1016\/j.jacc.2022.06.022_bib27","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.jacc.2010.11.018","article-title":"Cardiovascular events in patients with Fabry disease: natural history data from the Fabry Registry","volume":"57","author":"Patel","year":"2011","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.jacc.2022.06.022_bib28","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1148\/radiol.2019191385","article-title":"Left ventricular hypertrophy and late gadolinium enhancement at cardiac MRI are associated with adverse cardiac events in Fabry disease","volume":"294","author":"Hanneman","year":"2020","journal-title":"Radiology"},{"issue":"1","key":"10.1016\/j.jacc.2022.06.022_bib29","first-page":"136","article-title":"Left ventricle mass index, a confounding variable of global longitudinal strain to be noticed","volume":"114","author":"Correia","year":"2020","journal-title":"Arq Bras Cardiol"},{"issue":"1","key":"10.1016\/j.jacc.2022.06.022_bib30","doi-asserted-by":"crossref","first-page":"e20","DOI":"10.1016\/S2589-7500(20)30267-3","article-title":"Diagnosis and risk stratification in hypertrophic cardiomyopathy using machine learning wall thickness measurement","volume":"3","author":"Augusto","year":"2021","journal-title":"Lancet Digit Health\/"},{"issue":"5","key":"10.1016\/j.jacc.2022.06.022_bib31","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1681\/ASN.2016090964","article-title":"Characterization of classical and nonclassical Fabry disease","volume":"28","author":"Arends","year":"2017","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"8","key":"10.1016\/j.jacc.2022.06.022_bib32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0182379","article-title":"Retrospective study of long-term outcomes of enzyme replacement therapy in Fabry disease","volume":"12","author":"Arends","year":"2017","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.jacc.2022.06.022_bib33","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1007\/s10554-020-02105-y","article-title":"Does left ventricular function predict cardiac outcome in Anderson-Fabry disease?","volume":"37","author":"Spinelli","year":"2021","journal-title":"Int J Cardiovasc Imaging"},{"issue":"FI2","key":"10.1016\/j.jacc.2022.06.022_bib34","doi-asserted-by":"crossref","first-page":"f153","DOI":"10.1093\/europace\/eux261","article-title":"Ventricular arrhythmia and sudden cardiac death in Fabry disease","volume":"20","author":"Baig","year":"2018","journal-title":"Europace"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109722054705?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0735109722054705?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:50:21Z","timestamp":1760017821000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0735109722054705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":34,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["S0735109722054705"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2022.06.022","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Validated Model for Prediction of Adverse Cardiac Outcome in Patients With Fabry Disease","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2022.06.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.","name":"copyright","label":"Copyright"}]}}