{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T13:56:42Z","timestamp":1787579802142,"version":"build-2736575974"},"reference-count":13,"publisher":"Elsevier BV","issue":"15","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"vor","delay-in-days":380,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American College of Cardiology"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.jacc.2024.03.001","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T18:07:16Z","timestamp":1712599636000},"page":"1367-1369","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Unlocking the Gates of ISCHEMIA"],"prefix":"10.1016","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4878-8146","authenticated-orcid":false,"given":"Josip Andelo","family":"Borovac","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jacc.2024.03.001_bib1","doi-asserted-by":"crossref","first-page":"e34","DOI":"10.15420\/ecr.2021.16","article-title":"ISCHEMIA trial: key questions and answers","volume":"16","author":"Lopez-Sendon","year":"2021","journal-title":"Eur Cardiol Rev"},{"key":"10.1016\/j.jacc.2024.03.001_bib2","article-title":"Revascularization in stable coronary artery disease","volume":"377","author":"Al-Lamee","year":"2022","journal-title":"BMJ"},{"key":"10.1016\/j.jacc.2024.03.001_bib3","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.tcm.2021.10.011","article-title":"Clinical application of results of the ISCHEMIA trial","volume":"33","author":"Schnur","year":"2023","journal-title":"Trends Cardiovasc Med"},{"key":"10.1016\/j.jacc.2024.03.001_bib4","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1056\/NEJMoa070829","article-title":"Optimal medical therapy with or without PCI for stable coronary disease","volume":"356","author":"Boden","year":"2007","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2024.03.001_bib5","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1056\/NEJMoa1915922","article-title":"Initial invasive or conservative strategy for stable coronary disease","volume":"382","author":"Maron","year":"2020","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jacc.2024.03.001_bib6","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1056\/NEJMoa1916370","article-title":"Health-status outcomes with invasive or conservative care in coronary disease","volume":"382","author":"Spertus","year":"2020","journal-title":"N\u00a0Engl J Med"},{"issue":"2","key":"10.1016\/j.jacc.2024.03.001_bib7","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jacc.2021.09.005","article-title":"2021 ACC\/AHA\/SCAI guideline for coronary artery revascularization: executive summary: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"79","author":"Lawton","year":"2022","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2024.03.001_bib8","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1093\/eurheartj\/ehu278","volume":"35","author":"Windecker","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jacc.2024.03.001_bib9","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","article-title":"2019 ESC guidelines for the diagnosis and management of chronic coronary syndromes: the task force for the diagnosis and management of chronic coronary syndromes of the European Society of Cardiology (ESC)","volume":"41","author":"Knuuti","year":"2020","journal-title":"Eur Hear J"},{"issue":"15","key":"10.1016\/j.jacc.2024.03.001_bib10","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.jacc.2024.02.019","article-title":"Variation in health status with invasive vs conservative management of chronic coronary disease","volume":"83","author":"Arnold","year":"2024","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jacc.2024.03.001_bib11","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1161\/CIRCULATIONAHA.121.057363","article-title":"Comprehensive quality-of-life outcomes with invasive versus conservative management of chronic coronary disease in ISCHEMIA","volume":"145","author":"Mark","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.jacc.2024.03.001_bib12","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1001\/jamacardio.2020.7478","article-title":"Interpretation of the Seattle Angina Questionnaire as an outcome measure in clinical trials and clinical care","volume":"6","author":"Thomas","year":"2021","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jacc.2024.03.001_bib13","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1161\/CIR.0000000000001162","article-title":"Shared decision-making and cardiovascular health: a scientific statement from the American Heart Association","volume":"148","author":"Himmelfarb","year":"2023","journal-title":"Circulation"}],"container-title":["Journal of the American College of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073510972400487X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073510972400487X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T01:04:58Z","timestamp":1744765498000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073510972400487X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":13,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["S073510972400487X"],"URL":"https:\/\/doi.org\/10.1016\/j.jacc.2024.03.001","relation":{},"ISSN":["0735-1097"],"issn-type":[{"value":"0735-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Unlocking the Gates of ISCHEMIA","name":"articletitle","label":"Article Title"},{"value":"Journal of the American College of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2024.03.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jacc.2024.02.019","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 by the American College of Cardiology Foundation. Published by Elsevier.","name":"copyright","label":"Copyright"}]}}